IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02147

Kento Furuya , Naoya Itoh

{"title":"Urethrocutaneous fistula and subcutaneous abscess in the inguinal region with bacteremia caused by Bilophila wadsworthia in a Japanese patient: A case report","authors":"Kento Furuya , Naoya Itoh","doi":"10.1016/j.idcr.2025.e02147","DOIUrl":"10.1016/j.idcr.2025.e02147","url":null,"abstract":"<div><div><em>Bilophila wadsworthia</em> is an anaerobic, gram-negative bacillus commonly associated with acute appendicitis. However, bacteremia is exceedingly rare. Herein, we report a case of <em>B. wadsworthia</em> bacteremia associated with a urethrocutaneous fistula and a subcutaneous abscess in the left inguinal region. A 75-year-old man was referred to our hospital due to persistent fever despite piperacillin treatment. The patient was diagnosed with a urethrocutaneous fistula and a subcutaneous abscess in the left inguinal region. <em>B. wadsworthia</em> was isolated from his blood culture and identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Subsequently, the patient underwent a four-week course of piperacillin-tazobactam therapy. Since a susceptibility breakpoint has not been established for <em>B. wadsworthia</em>, standardized treatment guidelines are currently unavailable. This case represents the first successful treatment of <em>B. wadsworthia</em> bacteremia with piperacillin-tazobactam, suggesting it may be an effective therapeutic option for infections caused by <em>B. wadsworthia</em>.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02147"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual Peril: A rare case of simultaneous Bartonella and Brucella Endocarditis with unique epidemiological and clinical challenges

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02161

Qusai Alqudah , Akankcha Alok , Vidya S. Kollu

引用次数: 0

Disseminated histoplasmosis with oral involvement and co-infection with Pneumocystis in a patient with HIV: A case report 播散性组织胞浆菌病伴口腔感染并合并肺囊虫病1例

IF 1.1

IDCases Pub Date : 2024-11-26 DOI: 10.1016/j.idcr.2024.e02119

Susanne O Ajao , Nehar Damle , Michelle Zhao , Gabriela Ferreira , Keith K Kaye , John P Mills

{"title":"Disseminated histoplasmosis with oral involvement and co-infection with Pneumocystis in a patient with HIV: A case report","authors":"Susanne O Ajao , Nehar Damle , Michelle Zhao , Gabriela Ferreira , Keith K Kaye , John P Mills","doi":"10.1016/j.idcr.2024.e02119","DOIUrl":"10.1016/j.idcr.2024.e02119","url":null,"abstract":"<div><div>Oral manifestations of disseminated histoplasmosis are rare but can present in immunocompromised individuals. We report a case of disseminated Histoplasmosis presenting with presumed oral involvement and <em>Pneumocystis jirovecii</em> pneumonia in a seropositive HIV individual. A 32-year-old male with HIV presented to the emergency department for a two-week history of abdominal pain and a tongue ulcer in the setting of significant weight loss, blood-tinged sputum, and non-adherence with antiretroviral therapy for three years. Physical exam revealed a verrucous ulcer on the lateral aspect of the tongue. CT scan of the chest revealed diffuse bilateral pulmonary nodules and ground glass opacities. At presentation, his CD4 + count was 12 cells/mm<sup>3</sup>. During his hospitalization, he developed acute hypoxic respiratory failure requiring non-invasive ventilation. His urine histoplasma antigen was positive at greater than 25 ng/mL and liposomal amphotericin was started. Shortly thereafter, <em>Pneumocystis jirovecii</em> PCR on bronchoalveolar lavage returned positive prompting additional therapy with trimethoprim-sulfamethoxazole. At discharge, the patient had no respiratory symptoms and near-resolution of his tongue ulcer.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02119"},"PeriodicalIF":1.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clostridial gas gangrene involving the brain, gallbladder, heart, and soft tissue: A case report and literature review 累及大脑、胆囊、心脏和软组织的梭状芽孢杆菌气性坏疽：病例报告和文献综述

IF 1.1

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e02073

Ashton D. Hall , Joshua M. Ferreri , Jennifer E. Baker , Eleanor A. Powell , Imran Ahmed , Timothy T. Klostermeier , Keith M. Luckett

{"title":"Clostridial gas gangrene involving the brain, gallbladder, heart, and soft tissue: A case report and literature review","authors":"Ashton D. Hall , Joshua M. Ferreri , Jennifer E. Baker , Eleanor A. Powell , Imran Ahmed , Timothy T. Klostermeier , Keith M. Luckett","doi":"10.1016/j.idcr.2024.e02073","DOIUrl":"10.1016/j.idcr.2024.e02073","url":null,"abstract":"<div><p>Clostridial gas gangrene (CGG) is among the most rapidly spreading infections in humans, with mortality rates approaching 100 % if not treated promptly. Most cases follow traumatic inoculation, although spontaneous infections occur in a minority of patients with immunodeficiency. Spontaneous CGG is primarily caused by <em>Clostridium septicum</em>, whereas traumatic infection is associated with <em>Clostridium perfringens</em>. Patients with CGG present abruptly with rapidly progressive symptoms, underscoring the importance of early recognition, prompt surgical intervention, and appropriate antimicrobial therapy. We describe an illustrative case of spontaneous CGG caused by <em>C. perfringens</em> in a polymorbid 73-year-old female patient. Despite aggressive medical and surgical management, she succumbed to metastatic infection within 48 h of presentation.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"38 ","pages":"Article e02073"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001495/pdfft?md5=0f086d239b55083580bb1cff5f7ad56d&pid=1-s2.0-S2214250924001495-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142171761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of Bacillus subtilis variant natto-induced persistent bacteremia with liver and splenic abscesses in an immunocompetent patient 一例罕见的枯草芽孢杆菌变异纳豆诱发的持续性菌血症，免疫功能正常的患者伴有肝脾脓肿

IF 1.5

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e01925

Tetsuro Amemiya , Kiyofumi Ohkusu , Miku Murayama , Tomokiyo Yamamoto , Naoya Itoh

{"title":"A rare case of Bacillus subtilis variant natto-induced persistent bacteremia with liver and splenic abscesses in an immunocompetent patient","authors":"Tetsuro Amemiya , Kiyofumi Ohkusu , Miku Murayama , Tomokiyo Yamamoto , Naoya Itoh","doi":"10.1016/j.idcr.2024.e01925","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01925","url":null,"abstract":"<div><p><em>Bacillus subtilis var. natto</em>, a low-pathogenic bacterium used in the traditional Japanese food \"natto\" (fermented soybeans), has rarely been reported as a pathogen of infectious diseases in humans. Herein, we report the first case of persistent bacteremia caused by <em>B. subtilis var. natto</em> in an immunocompetent patient without any gastrointestinal involvement. A 53-year-old Japanese woman who had been consuming natto every day was admitted to our hospital with complaints of fever and chills. <em>B. subtilis</em> was isolated from blood cultures collected during the initial visit. Abdominal contrast-enhanced computed tomography (CT) showed multiple low-absorption areas in the liver and spleen. Treatment commenced with vancomycin; however, <em>Bacillus sp.</em> was re-detected in the blood culture on day 4 after treatment initiation. The blood culture on day 8 was negative. Subsequently, the treatment was switched to ampicillin-sulbactam and oral amoxicillin-clavulanic acid, and the patient recovered after 28 days of treatment from the time the blood cultures became negative. Contrast-enhanced CT of the abdomen at the end of treatment showed that the multiple low-absorption areas in the liver and spleen had disappeared. Later, the variant of the bacteria was identified as <em>B. subtilis var. natto</em> by DNA analysis. <em>B. subtilis var. subtilis</em> and <em>B. subtilis var. natto</em> cannot be distinguished using matrix-assisted laser desorption/ionization-time of flight mass spectrometry or 16S rRNA analysis. Biotin auxotrophy of <em>B. subtilis var. natto</em> is used to distinguish between the two variants.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"35 ","pages":"Article e01925"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000015/pdfft?md5=a945a8508e139d40307a82fc0daf4b1d&pid=1-s2.0-S2214250924000015-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139487562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of Staphylococcus epidermidis osteomyelitis in the absence of spine hardware 一例无脊柱硬件的表皮葡萄球菌骨髓炎病例

IF 1.5

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e01928

Erin Coonahan , Bita Shahrvini , Morgan Birabaharan , Nikdokht Farid , Annie Cowell

{"title":"A case of Staphylococcus epidermidis osteomyelitis in the absence of spine hardware","authors":"Erin Coonahan , Bita Shahrvini , Morgan Birabaharan , Nikdokht Farid , Annie Cowell","doi":"10.1016/j.idcr.2024.e01928","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01928","url":null,"abstract":"<div><p><em>Staphylococcus epidermidis</em> is a typically indolent pathogen that is often considered a blood culture contaminant. It is a rare and unexpected cause of osteomyelitis, especially in the absence of recent surgical intervention or orthopedic implants. We highlight a case in which a 90-year-old Caucasian male with no recent spine surgery was found to have osteomyelitis of the lumbar spine and repeat positive blood cultures for methicillin resistant <em>Staphylococcus epidermidis</em> (MRSE). Further investigation revealed a history of mitral valve replacement and a new diagnosis of endocarditis leading to persistent bacteremia and seeding of his lumbar vertebrae. This case demonstrates that <em>S. epidermidis</em> can cause vertebral osteomyelitis resulting in severe complications that are more similar to highly pathogenic bacteria. We describe the steps to diagnosing this chronic undetected infection and related comorbidities.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"35 ","pages":"Article e01928"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000040/pdfft?md5=cfdd5cb8158848fb335d83e108f2dd73&pid=1-s2.0-S2214250924000040-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139493224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Latent melioidosis activation presenting with urinary tract infection and bacteremia 以尿路感染和菌血症为表现的潜伏美拉德氏病激活症

IF 1.5

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e02007

Seohyeon Im , Ariane Paz y Mino , Estefany Garces , Sarah Altamimi

引用次数: 0

White piedra on pediatric scalp: A case report 小儿头皮上的白色斑块：病例报告

IF 1.5

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e02002

Julia Brigagão de Carvalho Sugai , Nayara Pelizaro Di Rito , Alexandre Lourenço , Ronei Luciano Mamoni , Ana Carolina Da Mota Falleiros , Celia Antonia Xavier de Moraes Alves , Glaucos Ricardo Paraluppi

引用次数: 0

A rare case of candida osteomyelitis of the mandible associated with osteoradionecrosis and biofilm formation 一例罕见的下颌骨念珠菌骨髓炎，伴有骨坏死和生物膜形成

IF 1.1

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e02029

Gabriel A. Godart, Sammer M. Elwasila, Ravindra V. Durvasula

{"title":"A rare case of candida osteomyelitis of the mandible associated with osteoradionecrosis and biofilm formation","authors":"Gabriel A. Godart, Sammer M. Elwasila, Ravindra V. Durvasula","doi":"10.1016/j.idcr.2024.e02029","DOIUrl":"10.1016/j.idcr.2024.e02029","url":null,"abstract":"<div><p><em>Candida</em> osteomyelitis, in general, is a relatively rare manifestation compared to its bacterial counterparts. The mandible's involvement is rarer, lacking established management and fewer guidelines. Herein, we aim to illustrate the significant challenge in treatment, namely due to the persistent and resistant nature of <em>Candida albicans</em>-associated biofilm. A multidisciplinary approach involving adjunctive use of antifungals with surgical interventions is typically necessary and feasible in this case. However, surgical interventions may not always be possible in challenging instances in which the patient may be structurally (including osteoradionecrosis) and vascularly compromised, raising questions about the feasibility of standard-of-care as well as the success of alternative therapies aimed at disrupting biofilm formation. Clinicians should maintain a high index of suspicion for complicating, deep-seated Candidiasis in at-risk populations and endeavor to treat as aggressively as possible to limit recurrent disease owing to persistence.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02029"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001057/pdfft?md5=28b58305e182e75a7496dbc9d447e7ed&pid=1-s2.0-S2214250924001057-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141729088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival in a pediatric patient with cerebral aspergillosis: A case report 脑曲霉菌病儿科患者的存活率：病例报告

IF 1.5

IDCases Pub Date : 2024-01-01 DOI: 10.1016/j.idcr.2024.e01948

Ana Paula Ramírez-Acosta , Lilian Danae Acosta-Yebra , Mariela Guadalupe Macedo-Montero , Gilberto Flores-Vargas , Nicolás Padilla-Raygoza

{"title":"Survival in a pediatric patient with cerebral aspergillosis: A case report","authors":"Ana Paula Ramírez-Acosta , Lilian Danae Acosta-Yebra , Mariela Guadalupe Macedo-Montero , Gilberto Flores-Vargas , Nicolás Padilla-Raygoza","doi":"10.1016/j.idcr.2024.e01948","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01948","url":null,"abstract":"<div><p>Aspergillosis is an infrequent infection in the Central Nervous System with a mortality rate higher than 95 %. Early diagnosis is challenging and crucial. In this report, we present the case of a six-year-old female with an intense headache accompanied by left hemiparesis, gaze deviation, horizontal nystagmus, and vomiting of mucous content on five occasions. After several approaches, a cerebrospinal fluid PCR resulted positive for <em>Aspergillus</em> spp., and then management started with amphotericin B at 2.6 mg/kg/day and was managed to have voriconazole. She survived, and two years after her first hospital admission, she suffered from cerebral aspergillosis sequelae. An area of improvement is the coordination between the request and delivery of studies outside the institution. In this case, the patient´s mother did not report the analysis results on time, delaying the diagnosis.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01948"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000246/pdfft?md5=d094d59ad0529dd6463d3d1419e6f002&pid=1-s2.0-S2214250924000246-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140618547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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