IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-04-21 DOI: 10.1016/j.idcr.2026.e02577

Ju Wang, Jun Qiu, Chaogui Zhang

{"title":"Crusted scabies complicated by septic shock: a fatal case report with incidental detection of Sarcoptes scabiei DNA in peripheral blood","authors":"Ju Wang, Jun Qiu, Chaogui Zhang","doi":"10.1016/j.idcr.2026.e02577","DOIUrl":"10.1016/j.idcr.2026.e02577","url":null,"abstract":"<div><div>Crusted scabies is a severe form of scabies characterized by massive mite burden and profound immune dysregulation. Secondary bacterial infection is common and may progress to sepsis with fatal outcomes. We report a fatal case of crusted scabies complicated by septic shock in a 58-year-old man with diabetes mellitus and chronic dermatitis. The patient presented with diffuse erythroderma, extensive hyperkeratotic crusts, and deep skin fissures, and several household members had similar pruritic skin lesions. Laboratory investigations revealed marked eosinophilia, extremely elevated serum immunoglobulin E levels, and multiorgan dysfunction. Peripheral blood metagenomic next-generation sequencing identified multiple bacterial pathogens and incidentally detected Sarcoptes scabiei DNA. Despite broad-spectrum antimicrobial therapy, antiparasitic treatment, and intensive supportive care, the patient deteriorated and died. This case highlights crusted scabies as a potentially lethal condition when complicated by severe bacterial infection and underscores the need for cautious interpretation of parasitic DNA detected in blood, particularly in non-invasive ectoparasitic diseases.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"44 ","pages":"Article e02577"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herpes zoster mimicking sciatica: A diagnostic pitfall in immunocompetent middle-aged adult with low back pain 带状疱疹模拟坐骨神经痛：一个诊断缺陷在免疫功能正常的中年人腰痛

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-05-04 DOI: 10.1016/j.idcr.2026.e02598

Daisuke Hori , Yuichi Sakamoto

{"title":"Herpes zoster mimicking sciatica: A diagnostic pitfall in immunocompetent middle-aged adult with low back pain","authors":"Daisuke Hori , Yuichi Sakamoto","doi":"10.1016/j.idcr.2026.e02598","DOIUrl":"10.1016/j.idcr.2026.e02598","url":null,"abstract":"<div><div>Herpes zoster (HZ) involving lumbosacral dermatomes can mimic sciatica, leading to diagnostic delays. While HZ is more common in older or immunocompromised individuals, it can occur in immunocompetent middle-aged adults, presenting diagnostic challenges due to atypical presentations, particularly in patients with chronic pain. We report a 40-year-old immunocompetent male with chronic low back pain who presented with an erythematous gluteal rash and acute radiating left leg pain following a chiropractic session. The rash was initially misdiagnosed as eczema at a dermatology clinic, and the leg pain was attributed to lumbar radiculopathy due to the temporal association with mechanical intervention. The patient’s own attribution of symptoms, together with the initial clinical framing, led to a delay in recognizing the underlying viral etiology. By Day 6, the clinical evolution of the rash into grouped vesicles and the presence of marked allodynia, despite a negative straight leg raise test, supported the diagnosis of lumbosacral HZ. Treatment with oral famciclovir resulted in rapid symptomatic improvement. This case underscores the importance of considering HZ in the differential diagnosis of acute radicular pain, even in the absence of typical early vesicular eruptions. It also highlights how cognitive biases—such as anchoring to a musculoskeletal cause and framing by the primary dermatological complaint—can impede diagnostic reasoning. Clinicians should maintain a high index of suspicion for HZ in patients with unilateral radicular pain and remain vigilant against cognitive pitfalls to ensure timely antiviral intervention.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"44 ","pages":"Article e02598"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147944976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corynebacterium silvaticum in a game-handling butcher: A new zoonotic pathogen of human infections 一种新的人类感染的人畜共患病原体

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-05-14 DOI: 10.1016/j.idcr.2026.e02610

Andreas Sing , Alexandra Dangel , Vyacheslav G. Melnikov , Hildegard Angermeier , Katja Bengs , Robert B. Brauer , Anja Berger

引用次数: 0

BCG gone rogue: A case report of disseminated Mycobacterium bovis 卡介苗叛变：传播性牛分枝杆菌1例报告

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-05-14 DOI: 10.1016/j.idcr.2026.e02609

Youssef Saklawi , Margaret Conrad , Mary Ann Kirkconnell Hall , Wassim Abdallah , Hady Samaha

{"title":"BCG gone rogue: A case report of disseminated Mycobacterium bovis","authors":"Youssef Saklawi , Margaret Conrad , Mary Ann Kirkconnell Hall , Wassim Abdallah , Hady Samaha","doi":"10.1016/j.idcr.2026.e02609","DOIUrl":"10.1016/j.idcr.2026.e02609","url":null,"abstract":"<div><h3>Introduction</h3><div>Bacillus Calmette–Guérin (BCG) bladder instillation is an effective therapy for non–muscle-invasive bladder cancer. Disseminated <em>Mycobacterium bovis</em> infection is a rare but potentially life-threatening complication. Despite increasing use of intravesical BCG, evidence-based guidance regarding its administration in immunocompromised patients remains limited. Here, we report a case of disseminated <em>M. bovis</em> infection presenting as fever of unknown origin.</div></div><div><h3>Case presentation</h3><div>A 59-year-old man presented to the hospital with fevers and chills. His past medical history was significant for renal transplantation with subsequent graft failure. He was maintained on tacrolimus 3 mg twice daily and prednisone 10 mg daily. He also had a history of bladder cancer treated with intravesical BCG immunotherapy 2 years prior to presentation. His hospital course was complicated by persistent undulating fevers. Computed tomography of the chest revealed a small cavitary lesion in the right upper lobe, and positron emission tomography imaging demonstrated increased uptake in the right iliopsoas muscle. A QuantiFERON Gold tuberculosis test was positive. Thirty days after presentation, acid-fast bacillus (AFB) blood cultures obtained at initial presentation, as well as AFB cultures from bronchoalveolar lavage and iliopsoas aspirate, grew pyrazinamide-resistant <em>Mycobacterium tuberculosis</em> complex. Subsequent sequencing identified <em>M. bovis</em>, consistent with disseminated infection related to prior intravesical BCG therapy.</div></div><div><h3>Conclusion</h3><div>This case of fever of unknown origin was ultimately attributed to disseminated <em>M. bovis</em> infection, likely related to prior intravesical BCG therapy in an immunocompromised patient. Early recognition of this rare complication is critical, as disseminated <em>M. bovis</em> infection may present with severe systemic illness and multi-organ involvement.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"44 ","pages":"Article e02609"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147944887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of infective endocarditis caused by Streptococcus gordonii complicated with bacterial meningitis and cerebral infarction —— Application of metagenomic next-generation sequencing (mNGS) 戈多氏链球菌致感染性心内膜炎合并细菌性脑膜炎合并脑梗死1例——新一代宏基因组测序（mNGS）的应用

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-05-15 DOI: 10.1016/j.idcr.2026.e02608

Jinchun Ye , Lu Ye , Wei Sun , Shuhua Xie , Zhaohui Lai

{"title":"A case of infective endocarditis caused by Streptococcus gordonii complicated with bacterial meningitis and cerebral infarction —— Application of metagenomic next-generation sequencing (mNGS)","authors":"Jinchun Ye , Lu Ye , Wei Sun , Shuhua Xie , Zhaohui Lai","doi":"10.1016/j.idcr.2026.e02608","DOIUrl":"10.1016/j.idcr.2026.e02608","url":null,"abstract":"<div><div>This study reports a case of infective endocarditis (IE) caused by <em>Streptococcus gordonii</em>. The patient presented with cerebral infarction as the initial manifestation, complicated by bacterial meningitis and mitral regurgitation. The diagnosis of <em>Streptococcus gordonii</em>-induced infective endocarditis was facilitated by metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF). <em>Streptococcus gordonii</em> was detected by CSF mNGS within 40 h after admission, which was 30 h earlier than the positive result of blood culture. During anti-infective therapy, the patient experienced recurrent thromboembolic events and underwent emergency mechanical thrombectomy due to occlusion of the left vertebral artery. Despite aggressive treatment, the patient eventually died of heart failure. This case indicates that <em>Streptococcus gordonii</em> is a rare pathogen of infective endocarditis, and its clinical presentation complicated by cerebral infarction and bacterial meningitis is distinctive; particularly, complex cases requiring mechanical thrombectomy are extremely rare in clinical practice. As an important complement to conventional bacterial culture, mNGS can shorten diagnostic delay, especially in patients with negative blood or CSF cultures. For patients with concurrent cerebral infarction and meningitis, the possibility of infective endocarditis should be highly suspected, and indications for valve replacement surgery should be evaluated as early as possible in high-risk cases.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"44 ","pages":"Article e02608"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147995116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment of tuberculous wounds using Maggot Debridement Therapy (MDT): A case report 应用蛆虫清创治疗结核性伤口成功一例报告

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-05-05 DOI: 10.1016/j.idcr.2026.e02593

Pin Zuo , Linxuan Zou , Rujia Zhou , Renbo Li , Junwei Zong , Shouyu Wang , Jian Sun

引用次数: 0

Gordonia bronchialis chronic tenosynovitis of the right wrist and hand in an immunocompetent patient: A case report 支气管Gordonia慢性腱鞘炎右腕和手在免疫功能正常的病人：一个病例报告

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-04-19 DOI: 10.1016/j.idcr.2026.e02580

Donnapa Suparatit , Phadungkiat Khamnoi , Parichat Salee

{"title":"Gordonia bronchialis chronic tenosynovitis of the right wrist and hand in an immunocompetent patient: A case report","authors":"Donnapa Suparatit , Phadungkiat Khamnoi , Parichat Salee","doi":"10.1016/j.idcr.2026.e02580","DOIUrl":"10.1016/j.idcr.2026.e02580","url":null,"abstract":"<div><div><em>Gordonia bronchialis</em> is a rare aerobic, gram-positive, weakly acid-fast actinomycete that is increasingly recognized as a human pathogen following advances in microbiologic identification. However, it remains frequently misidentified because of phenotypic overlap with <em>Mycobacterium</em> and <em>Nocardia</em> species. Musculoskeletal infections caused by this organism are exceptionally uncommon. We report a 67-year-old immunocompetent male farmer who presented with a one-year history of progressive swelling and functional impairment of the right wrist and hand. Magnetic resonance imaging demonstrated chronic flexor tenosynovitis with extensive rice body formation. The patient underwent open surgical tenosynovectomy. Routine bacterial, fungal, and molecular investigations were negative. Synovial tissue submitted for mycobacterial culture yielded slow-growing colonies after prolonged incubation, which were identified as <em>G. bronchialis</em> using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Prolonged oral antimicrobial therapy with amoxicillin–clavulanate, doxycycline, and ciprofloxacin resulted in marked clinical improvement without recurrence. This case highlights <em>G. bronchialis</em> as a rare cause of chronic tenosynovitis mimicking tuberculous infection and underscores the importance of extended culture incubation and advanced diagnostic techniques in evaluating indolent, culture-negative musculoskeletal infections.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"44 ","pages":"Article e02580"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147747225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Missed opportunities and near-miss diagnoses in congenital syphilis: A case series of five infants at a tertiary care centre in Nepal 先天性梅毒的错失机会和差点错过的诊断：尼泊尔三级保健中心的五名婴儿的病例系列

IF 0.9

IDCases Pub Date : 2026-01-01 Epub Date: 2026-09-09 DOI: 10.1016/j.idcr.2026.e02751

Srijana Basnet, Luna Bajracharya, Rachana Shrestha, Pradeep Gupta, Prabina Shrestha

引用次数: 0

A rare case of primary lingual mucormycosis in an uncontrolled diabetic patient 一例罕见的原发性舌毛霉菌病在一个未控制的糖尿病患者。

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-05-24 DOI: 10.1016/j.idcr.2026.e02615

Alushika Jain , Nikita Bora , Amit Toshniwal

引用次数: 0

Streptobacillus moniliformis bacteremia in an afebrile patient: A rare case report 发热病人单核芽孢杆菌菌血症：罕见病例报告

IF 1

IDCases Pub Date : 2026-01-01 Epub Date: 2026-06-02 DOI: 10.1016/j.idcr.2026.e02632

Zirong Wu , Lin Zhang , Li Shi , Chunhua Wang , Weiliang Cao

{"title":"Streptobacillus moniliformis bacteremia in an afebrile patient: A rare case report","authors":"Zirong Wu , Lin Zhang , Li Shi , Chunhua Wang , Weiliang Cao","doi":"10.1016/j.idcr.2026.e02632","DOIUrl":"10.1016/j.idcr.2026.e02632","url":null,"abstract":"<div><div>Rat-bite fever (RBF), caused by <em>Streptobacillus moniliformis</em>, typically presents with fever, rash, and polyarthralgia, but we report an atypical afebrile case in a 36-year-old woman who presented with severe arthralgia and purpuric rash without fever. Laboratory findings revealed leukocytosis, elevated inflammatory markers (CRP 118.77 mg/L, ESR 64 mm/h), and acute kidney injury. Two sets of blood cultures grew <em>Streptobacillus moniliformis</em>, identified by Gram stain, colony morphology, and MALDI-TOF mass spectrometry (Bruker system, score 2.50). Antimicrobial susceptibility testing, performed according to CLSI M100 guidelines, demonstrated sensitivity to penicillin (MIC 0.032 mg/L), ceftriaxone, and other antibiotics. The patient was treated with intravenous penicillin (1.6 million units every 8 h for 14 days) and showed clinical improvement before discharge. This case underscores that fever may be absent in RBF and highlights that, in patients with compatible symptoms (e.g., rash, arthralgia) and potential rodent exposure, blood cultures should be considered even in the absence of fever, especially when other infectious or inflammatory causes are being evaluated, to avoid diagnostic delay.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"45 ","pages":"Article e02632"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148183603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IDCases最新文献