IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02235

Hiwot Mehari Beyene , Zenebe Daniel Getachew , Adugnaw Atnafu Atalay , Selamawit Tadesse Wendimagegn , Zeru Seyoum Wondimagegn

引用次数: 0

Corynebacterium striatum as a rare cause of septic arthritis in a native joint: A case report and review of the literature 纹状棒状杆菌作为一种罕见的原因，败血性关节炎在天然关节：一个病例报告和文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02275

Sakthi Gautham , Kaushik Kumar , Shiavax J. Rao

{"title":"Corynebacterium striatum as a rare cause of septic arthritis in a native joint: A case report and review of the literature","authors":"Sakthi Gautham , Kaushik Kumar , Shiavax J. Rao","doi":"10.1016/j.idcr.2025.e02275","DOIUrl":"10.1016/j.idcr.2025.e02275","url":null,"abstract":"<div><div>Septic arthritis commonly occurs due to gram-positive cocci and usually presents as acute monoarticular swelling and tenderness, often associated with systemic signs of sepsis. In rare scenarios, <em>Corynebacterium striatum,</em> a gram-positive bacillus, can cause septic arthritis. We present a rare case of native joint septic arthritis caused by <em>C. striatum</em> in an immunocompetent patient. A 74-year-old man with history of ESRD receiving HD presented with hematuria. He was found to have anemia and pyuria and was admitted for management of hematuria and UTI with ceftriaxone. Five days later, he developed new persistent fever and worsening leukocytosis, while receiving antibiotics. Examination revealed right knee swelling, erythema, and tenderness, with decreased range of motion. X-ray showed joint effusion for which he underwent right knee arthrocentesis and aspiration. Synovial fluid culture grew <em>C. striatum</em>, initially disregarded as a contaminant. Repeat cultures again grew <em>C. striatum</em>. He was treated with IV vancomycin and oral colchicine along with arthroscopic irrigation and debridement, and discharged on a 4-week course of vancomycin. <em>C. striatum</em> is typically a considered pathogen in immunocompromised individuals; however, emerging reports describe its role in infections among immunocompetent hosts. While <em>C. striatum</em> remains a rare cause of native joint septic arthritis, its isolation in multiple specimens in the appropriate clinical context should prompt clinicians to consider a true infection rather than contamination. Prompt identification and appropriate management is key to improving patient outcomes. Susceptibility testing helps guide targeted treatment for this emerging pathogen with increasing multi-drug resistance.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02275"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144178000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic cutaneous melioidosis with concomitant basal cell carcinoma 慢性皮肤类鼻疽病伴发基底细胞癌

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02255

Aldo Barajas-Ochoa, Julie Reznicek

引用次数: 0

Corrigendum to “An unusual case of varicella zoster encephalitis mimicking a glioblastoma on magnetic resonance imaging and magnetic resonance spectroscopy” [IDCases 39 (2025) e02124] “一个不寻常的水痘带状疱疹脑炎的磁共振成像和磁共振波谱模拟胶质母细胞瘤病例”的勘误表[IDCases 39 (2025) e02124]

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02127

Brenden Nago , Jeffrey E. Liu

引用次数: 0

Foscarnet-induced penile ulcer in a patient with cytomegalovirus coinfection refractory to ganciclovir and Clostridioides difficile: A case report 更昔洛韦和艰难梭菌难治性巨细胞病毒合并感染患者氟膦酸钠致阴茎溃疡1例

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02315

John Jairo Cardeño-Sánchez , Mariana Montoya-Castillo , Juan Ricardo Cadavid-Castrillón , Luis Felipe Higuita-Gutiérrez

{"title":"Foscarnet-induced penile ulcer in a patient with cytomegalovirus coinfection refractory to ganciclovir and Clostridioides difficile: A case report","authors":"John Jairo Cardeño-Sánchez , Mariana Montoya-Castillo , Juan Ricardo Cadavid-Castrillón , Luis Felipe Higuita-Gutiérrez","doi":"10.1016/j.idcr.2025.e02315","DOIUrl":"10.1016/j.idcr.2025.e02315","url":null,"abstract":"<div><div>Coinfections by cytomegalovirus and <em>Clostridioides difficile</em> are rare and can be life-threatening, especially in immunosuppressed patients. Their symptoms often overlap, thus generating a great diagnostic challenge, with the need for multiple diagnostic aids. Under certain conditions, combined antiviral treatment, requiring the addition of foscarnet, is necessary to control cytomegalovirus. The latter drug is relatively safe; however, adverse reactions should always be considered for proper management. We present a case of a patient with a history of Burkitt's lymphoma in complete remission, who received chemotherapy in the past, and currently is living with HIV with undetectable viral load and CD4+ count of 141 cells/mm3, who presented with cytomegalovirus coinfection with suspected resistance to ganciclovir and <em>Clostridioides difficile</em> colitis. The patient required treatment with foscarnet and developed a genital ulcer, secondary to this drug, and therefore it was necessary to suspend it.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02315"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alopecia as the initial presentation of secondary syphilis: A case report and review of literature 脱发作为第二梅毒的最初表现：一个病例报告和文献回顾

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02314

Sarah Alqhtani , Hala Danish , Raghad Alkharouby , Hadeel Altayeb

引用次数: 0

Diagnostic and therapeutic strategies for solitary pulmonary nodules mimicking malignancy: Insights from two cases of pulmonary tuberculosis 孤立性肺结节模拟恶性肿瘤的诊断和治疗策略：来自两例肺结核的见解

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02302

Xianlei Wang , Ying Zhang , Huan Zhang , Zhihua Zhang , Weile Xu

{"title":"Diagnostic and therapeutic strategies for solitary pulmonary nodules mimicking malignancy: Insights from two cases of pulmonary tuberculosis","authors":"Xianlei Wang , Ying Zhang , Huan Zhang , Zhihua Zhang , Weile Xu","doi":"10.1016/j.idcr.2025.e02302","DOIUrl":"10.1016/j.idcr.2025.e02302","url":null,"abstract":"<div><div>Pulmonary nodules present a diagnostic dilemma, particularly in differentiating tuberculous nodules from malignant lesions. Misdiagnosis may lead to unnecessary surgery or delayed treatment. We report two cases where solitary pulmonary nodules were initially suspected as malignancies but were ultimately diagnosed as pulmonary tuberculosis. In Case #1, a diabetic patient with a left lower lobe nodule underwent resection, and postoperative pathology and molecular tests confirmed tuberculosis. In Case #2, a patient with prior pulmonary surgery developed a new right upper lobe nodule. Despite malignant imaging features, CT-guided biopsy and GeneXpert plus nanopore sequencing confirmed Mycobacterium tuberculosis, and anti-tuberculosis therapy led to lesion absorption without repeat surgery. CT imaging alone is insufficient to distinguish tuberculosis from malignancy. Integrating percutaneous biopsy with molecular diagnostics is essential for accurate diagnosis. In high-risk patients, postoperative anti-tuberculosis treatment should be considered. An individualized, multidisciplinary approach is critical to avoid overtreatment and improve outcomes.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02302"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brevibacterium ravenspurgense bacteremia 乌鸦短杆菌菌血症

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02318

Fang Xingyan , Ou Xingkun , Hu Yonglin , Daimin Xiao

引用次数: 0

Exploring the granulomatous manifestations of secondary syphilis: A case report 探讨二期梅毒肉芽肿表现1例

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02286

Margaret Kaszycki , Olayemi Sokumbi , Jason Sluzevich

{"title":"Exploring the granulomatous manifestations of secondary syphilis: A case report","authors":"Margaret Kaszycki , Olayemi Sokumbi , Jason Sluzevich","doi":"10.1016/j.idcr.2025.e02286","DOIUrl":"10.1016/j.idcr.2025.e02286","url":null,"abstract":"<div><div>Syphilis, caused by <em>Treponema pallidum</em>, progresses through distinct stages, with secondary syphilis often being the first presentation within 6–11 weeks after exposure. Although referred to as the “great mimicker”, secondary syphilis has typical clinic and histopathological features. This report presents a case of secondary syphilis with absent palmoplantar involvement and unusual granulomatous pathological manifestations. Our patient presented with a diffuse headache and a spreading non-pruritic rash, which progressed to involve the chest, abdomen, upper extremities, and face. Diagnostic workup, including serology and biopsy, confirmed secondary syphilis with granulomatous inflammation. Histopathological examination revealed vacuolar interface dermatitis, neutrophilic mounds, and granulomatous inflammation, while a Treponema pallidum immunohistochemical stain identified spirochetes located primarily in the dermis. This case, representing the earliest documented instance of secondary granulomatous syphilis, challenges the typical association of granulomatous inflammation with tertiary syphilis and delayed hypersensitivity reactions. Instead, we propose that granuloma formation and the lack of palmoplantar involvement are an interrelated phenomena that occur concurrently in this rare subtype of secondary syphilis. We hypothesize that the sparing of the palms and soles, areas with thickened epidermis, may indicate a dermal-based granulomatous response. The patient responded well to IV penicillin therapy, highlighting the importance of early detection and treatment in managing syphilis with atypical histopathological features. With the recent increase in syphilis cases, this highlights the importance of recognizing both clinical and histopathological changes for prompt diagnosis and treatment.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02286"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post Varicella-Zoster virus transverse myelitis: Diagnostic and therapeutic challenges – A case report and literature review 后水痘带状疱疹病毒横贯脊髓炎：诊断和治疗的挑战- 1例报告和文献复习

IF 1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02336

Mohammad Mehdi Shadravan , Farnoosh Farshchian , Alireza Rajaei , Ilad Alavi Darazam , Reza Naseri , Faezeh Maghsudloo

{"title":"Post Varicella-Zoster virus transverse myelitis: Diagnostic and therapeutic challenges – A case report and literature review","authors":"Mohammad Mehdi Shadravan , Farnoosh Farshchian , Alireza Rajaei , Ilad Alavi Darazam , Reza Naseri , Faezeh Maghsudloo","doi":"10.1016/j.idcr.2025.e02336","DOIUrl":"10.1016/j.idcr.2025.e02336","url":null,"abstract":"<div><h3>Introduction</h3><div>Acute transverse myelitis (ATM) is a rare inflammatory disorder that affects the spinal cord, leading to sudden weakness, sensory deficits, and bowel/bladder dysfunction. Also rare, this condition can be caused by infections such as the Varicella-zoster virus (VZV) or can occur as a complication of systemic lupus erythematosus (SLE). It has been reported to be more prevalent in SLE patients compared to VZV infections. We present a case of a patient with a history of SLE and evidence of vesicular rash from VZV infection.</div></div><div><h3>Case report</h3><div>A 61-year-old female presented with progressive weakness in her lower limbs. Two weeks before, she had developed a vesicular rash due to a VZV infection in the T6-T9 dermatomes, which was followed by paraparesis, sensory loss, and urinary retention. She also had a history of SLE. During the physical examination, muscle strength and sensation were decreased in the lower limbs. MRI revealed central myelopathy from T6 to T10. In laboratory tests, VZV PCR was positive, and Aquaporin-4 was also negative. The patient was treated with IV corticosteroid pulse and ganciclovir, followed by plasma exchange. resulted in partial recovery.</div></div><div><h3>Conclusions</h3><div>This case highlights VZV-induced TM (VZV-TM) in an immunocompromised patient with underlying SLE. Despite overlapping etiologies, a thorough clinical, radiologic, and laboratory evaluation, including a positive CSF VZV PCR and the absence of a SLE flare, supported VZV-TM as the final diagnosis. Prompt antiviral therapy and escalation to plasma exchange led to substantial neurological recovery.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02336"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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