IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01984
Jacob Beery , Kevin Roberston , Ashley Hynes , Adam Douglas , John Peters , Ryan Freedle , Robin Chamberland , Kevin Reilly , Getahun Abate
{"title":"Campylobacter gastroenteritis and bacteremia in an asplenic patient with a recent history of Yersinia Enterocolitis: Case report and literature review","authors":"Jacob Beery , Kevin Roberston , Ashley Hynes , Adam Douglas , John Peters , Ryan Freedle , Robin Chamberland , Kevin Reilly , Getahun Abate","doi":"10.1016/j.idcr.2024.e01984","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01984","url":null,"abstract":"<div><p>In this case report, we present a patient with a history of splenectomy and two recent hospital admissions for severe gastroenteritis with sepsis. The first hospital admission was for <em>Yersinia enterocolitica</em> and the second admission was for <em>Campylobacter fetus</em> gastroenteritis with bacteremia. During both admissions, the patient was treated with a prolonged course of antibiotics and later discharged with full recovery. In our review, we address the risk of enterocolitis in splenectomized patients.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01984"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221425092400060X/pdfft?md5=019e3a8b6ab8cda2abd88e7f8467b869&pid=1-s2.0-S221425092400060X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140906479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acquired bedaquiline and fluoroquinolones resistance during treatment follow-up in Oromia Region, North Shewa, Ethiopia","authors":"Getu Diriba , Ayinalem Alemu , Betselot Zerihun Ayano , Bazezew Yenew , Michael Hailu , Bedo Buta , Amanuel Wondimu , Zigba Tefera , Zerihun Ababu , Yerosen Ebisa , Shewki Moga , Gemechu Tadesse","doi":"10.1016/j.idcr.2024.e01988","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01988","url":null,"abstract":"<div><h3>Background</h3><p>Bedaquiline (BDQ) is an effective drug currently used for multidrug-resistant or rifampicin-resistant TB (MDR/RR-TB) and pre-extensively drug-resistant TB (pre-XDR-TB) treatment. However, resistance to this new drug is emerging. We discussed the characteristics of the first patient in Ethiopia who acquired BDQ and fluoroquinolones (FQs) resistance during treatment follow-up.</p></div><div><h3>Case report</h3><p>In this case report, we present the case of a 28-year-old male pulmonary TB patient diagnosed with MDR-TB who is a resident of the Oromia Region of North Shewa, Mulona Sululta Woreda, Ethiopia. Sputum specimen was collected initially and for treatment monitoring using culture and for phenotypic drug susceptibility testing (DST) to first-line and second-line TB drugs. Initially, the patient was infected with a mycobacterial strain resistant to the first-line anti-TB drugs Rifampicin (RIF), Isoniazid (INH), and Pyrazinamide (PZA). Later, during treatment, he acquired additional drug resistance to ethambutol (EMB), ofloxacin (OFX), levofloxacin (LFX), moxifloxacin (MFX), and BDQ. The patient was tested with MTBDR<em>plus</em> and MTBDR<em>sl</em> to confirm the presence of resistance-conferring mutation and mutation was detected in <em>rpoB, katG,</em> and <em>gyrA</em> genes. Finally, the patient was registered as having extensively drug-resistant tuberculosis (XDR-TB) and immediately started an individualized treatment regimen.</p></div><div><h3>Conclusion</h3><p>This case report data has revealed the evolution of BDQ resistance during treatment with a BDQ-containing regimen in Ethiopia. Therefore, there is a need for DST to new second-line drugs to monitor and prevent the spread of DR-TB.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01988"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000647/pdfft?md5=66283ef993a21b78e32db7140ead6942&pid=1-s2.0-S2214250924000647-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140948454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02026
Nathan B. Price , Emily S. Cormack , Kathryn R. Matthias , Kareem W. Shehab
{"title":"Chronic paronychia associated with fluconazole use in two pediatric patients with coccidioidomycosis","authors":"Nathan B. Price , Emily S. Cormack , Kathryn R. Matthias , Kareem W. Shehab","doi":"10.1016/j.idcr.2024.e02026","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02026","url":null,"abstract":"<div><p>Azoles are frequently used to treat systemic mycoses but have been associated with a number of adverse effects of the skin and skin appendages. Herein we describe two cases of chronic paronychia in pediatric patients receiving fluconazole for coccidioidomycosis. Their clinical characteristics are described, and the literature reviewed.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02026"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001021/pdfft?md5=aa5a9af2af549bff7c108e1acc30ebe0&pid=1-s2.0-S2214250924001021-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02019
Abdullah Balkhair , Badriya Al Adawi , Prashanth Kumar , Saja Mohammed , Saleh Baawain , Ruqaiya Al Harrasi , Glenneth Gallenero
{"title":"Melioidosis in a returned traveler: Case report and review of the imported cases in Oman","authors":"Abdullah Balkhair , Badriya Al Adawi , Prashanth Kumar , Saja Mohammed , Saleh Baawain , Ruqaiya Al Harrasi , Glenneth Gallenero","doi":"10.1016/j.idcr.2024.e02019","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02019","url":null,"abstract":"<div><p>Melioidosis is an emerging tropical infectious disease in travelers. We present a case of travel related melioidosis in a 65-year-old man with chronic obstructive pulmonary disease and end stage renal disease following a two-week business trip to Thailand and attendance of the Songkran festival. This case emphasizes that vigilance, heightened clinical suspicion, and use of appropriate microbiology diagnostic tools are of paramount importance for a timely diagnosis and successful management. With the ever-increasing global travel, infectious diseases specialists, microbiologists, and public health professionals are constantly challenged by unfamiliar infections in returned travelers.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02019"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000957/pdfft?md5=5816a6cfcf7dffc6fbcd5a639847f24d&pid=1-s2.0-S2214250924000957-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01939
El Mawla Zeinab , Zoghaib Dima , Al Saylami Haji
{"title":"Empyema Necessitans: A Case Report","authors":"El Mawla Zeinab , Zoghaib Dima , Al Saylami Haji","doi":"10.1016/j.idcr.2024.e01939","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01939","url":null,"abstract":"<div><h3>Introduction</h3><p>TB is a well-recognized cause of pulmonary infection. Empyema Necessitans is a rare complication of untreated empyema, mainly caused by mycobacterium tuberculosis. It mainly affects immunocompromised individuals.</p></div><div><h3>Case presentation</h3><p>We present a case of 28 years old gentleman, Sudanese, with intermittent fever, non-productive cough, weight loss and night sweats. Chest X-ray then CT chest revealed a large right pleural collection invading the chest wall. Chest tube was inserted, fluid analysis was taken, and a bronchoscopy was done. A diagnosis of Empyema Necessitans was confirmed and patient was started on anti-TB regimen with clinical improvement.</p></div><div><h3>Conclusion</h3><p>Empyema Necessitans is a severe disease, complicating pulmonary tuberculosis. Diagnosis can be a challenge. Surgical and medical approaches are both crucial in the treatment of EN. This case highlights the importance of early recognition and diagnosis of this rare but aggressive condition particularly in TB endemic area.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01939"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000155/pdfft?md5=1e97398dd5af86d1e67811a3ac42a879&pid=1-s2.0-S2214250924000155-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140342295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post operative abdominal wall mucormycosis infection after laparotomy for bowel perforation","authors":"Neha Kumta , Lawrence Huang , Gururaj Nagaraj , Lindsey Papacostas , Shradha Subedi","doi":"10.1016/j.idcr.2024.e01998","DOIUrl":"10.1016/j.idcr.2024.e01998","url":null,"abstract":"<div><p>Mucormycosis is a devastating disease with a high mortality rate, typically affecting immunosuppressed individuals. Postoperative surgical site infections due to mucromycosis are rare, with only a handful of cases reported in the literature. Here, we describe a fatal case of post operative abdominal wound infection caused by mucormycosis in an immunocompetent man in his 70 s, who developed the infection following a laparotomy for bowel perforation. Initially, the growth of fungal species from a superficial wound swab was not considered significant until the patient exhibited signs of worsening sepsis. Limited operative debridement was performed for prognostication, in accordance with the family’s wishes. There was evidence of extensive significant invasive fungal infection, marked by necrosis extending into the abdominal wall fat and muscle. The patient was then transitioned to comfort measures and subsequently died. This case emphasizes the importance of maintaining a high level of clinical suspicion for mucormycosis, even in patients with minimal risk factors, and highlights the importance of prompt and aggressive treatment.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01998"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221425092400074X/pdfft?md5=bbe4305f394eda5a124eb88c4a6d586c&pid=1-s2.0-S221425092400074X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141130359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multidrug-resistant aeromonas caviae causing cystitis in a renal failure patient","authors":"Jiao Zhou , Tianbing Xiao , Yuqing Huang , Jianrong Tang , Xiaobing Zhang , Bei Jia , Jianguo Wu","doi":"10.1016/j.idcr.2024.e01999","DOIUrl":"10.1016/j.idcr.2024.e01999","url":null,"abstract":"<div><p>A 49-year-old female with multiple myeloma complicated by renal failure had dysuria. The urine culture revealed multidrug-resistant <em>aeromonas caviae</em> during her hospital stay. Her symptoms and signs significantly improved after receiving a seven-day course of piperacillin-tazobactam treatment. She had no history of urinary tract infections(UTIs). On follow-up, she felt clinically well. <em>Aeromonas caviae</em> is a rare cause of UTI. We review previous cases of <em>aeromonas caviae</em> UTIs. The purpose of this case report is to assist in the diagnosis and management of a<em>eromonas caviae</em> cystitis.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e01999"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000751/pdfft?md5=9669a6fe85732fae90331b46509afb7d&pid=1-s2.0-S2214250924000751-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141144057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral scrofuloderma: An incessant entity","authors":"Parakriti Gupta , Ivneet Kour , Varsha Gupta , Varinder Saini , Lipika Singhal","doi":"10.1016/j.idcr.2024.e02097","DOIUrl":"10.1016/j.idcr.2024.e02097","url":null,"abstract":"<div><div>Scrofuloderma is most common presentation of cutaneous tuberculosis in India. A 15-years-old immunocompetent male presented with bilateral cervical necrotising lesions and was treated with ATTx9 months, without improvement. Patient was diagnosed with scrofuloderma and ZN staining revealed 2+acid-fast bacilli. Cartridge-based nucleic acid amplification test showed rifampicin resistance. Patient was initiated on shorter regimen, but deferred treatment owing to technical portal problems. After 3 months, neck swelling had enlarged and he was started on multi-drug regimen x24 months. This underlines requisite to consider scrofuloderma in differentials of bilateral cervical lesions and to periodically monitor compliance to prevent subsequent emergence of resistance.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"38 ","pages":"Article e02097"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142652423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01930
Jiafeng Zhang , Yaoting Liu , Hongkun Wu , Lin Zhou
{"title":"Is Shigella an under-recognized pathogen? A case of pyogenic cervical spondylitis caused by Escherichia coli and Shigella flexneri infection","authors":"Jiafeng Zhang , Yaoting Liu , Hongkun Wu , Lin Zhou","doi":"10.1016/j.idcr.2024.e01930","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01930","url":null,"abstract":"<div><p><em>Shigella</em> typically causes gastrointestinal infections, and extra-intestinal manifestations are rare. We report the first known case of pyogenic cervical spondylitis co-infected with <em>Escherichia coli</em> and <em>Shigella flexneri</em>, highlighting the diagnostic challenges and clinical implications. A 53-year-old woman presented with neck pain for one month. MRI revealed C6 and C7 vertebrae abscesses. The patient underwent anterior cervical debridement and bone-graft fusion. Intraoperative pus culture grew <em>Escherichia coli</em>, while metagenomic next-generation sequencing detected both <em>Escherichia coli</em> and <em>Shigella</em> species. Intravenous imipenem 500 mg every 6 h was administered, leading to full wound healing at a 6-month follow-up. This case emphasizes the importance of considering <em>Shigella</em> infection in the differential diagnosis of pyogenic spondylitis and demonstrates the utility of a multi-pronged diagnostic approach.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"35 ","pages":"Article e01930"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000064/pdfft?md5=47c725f08544c11e6d5dc088853105cc&pid=1-s2.0-S2214250924000064-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139674671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01966
Chuanchuan Liu , Hainin Fan
{"title":"Epididymal alveolar echinococcosis and tuberculosis co-infection: A case report","authors":"Chuanchuan Liu , Hainin Fan","doi":"10.1016/j.idcr.2024.e01966","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01966","url":null,"abstract":"<div><p>Alveolar echinococcosis (AE) is a common and significant public health problem caused by the larvae of the <em>Echinococcus multilocularis</em>. The occurrence of epididymal AE is rare and often overlooked in combination with mycobacterium tuberculosis infection. We report a case of a 34-year-old man who presented with right-sided scrotal enlargement with pain. Physical examination revealed an enlarged right scrotum with rupture. CT examination showed a blurred border and non-enhancing lesion on the right epididymis. Postoperative pathology and molecular biology identified an epididymal <em>E. multilocularis</em> infection. We report this rare case to emphasise the difficulty of preoperative diagnosis and the importance of complete surgical excision of the lesion.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01966"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000428/pdfft?md5=3397fe0fddeace7d11c53e33097aff05&pid=1-s2.0-S2214250924000428-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140607104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}