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Mumps-associated hepatitis: A rare clinical presentation

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02207

Mikiyas G. Teferi , Abel K. Gulma , Meron T. Akalu , Getaw W. Hassen , Elias M. Gashaw , Nahom D. Gerer

{"title":"Mumps-associated hepatitis: A rare clinical presentation","authors":"Mikiyas G. Teferi , Abel K. Gulma , Meron T. Akalu , Getaw W. Hassen , Elias M. Gashaw , Nahom D. Gerer","doi":"10.1016/j.idcr.2025.e02207","DOIUrl":"10.1016/j.idcr.2025.e02207","url":null,"abstract":"<div><h3>Introduction</h3><div>Mumps is a viral infection that principally affects the salivary glands, but it results in a range of complications, including orchitis, pancreatitis, and meningoencephalitis. Hepatic involvement is exceedingly rare and underreported in adults. Here, we present a peculiar case of mumps-associated hepatitis, highlighting its diagnostic challenges, clinical course, and management.</div></div><div><h3>Case presentation</h3><div>An unvaccinated 20-year-old male presented with a two-week history of fever, malaise, and bilateral parotid gland swelling, along with nausea, anorexia, and right upper quadrant discomfort. Tender parotid gland enlargement, scleral icterus, and bilateral testicular tenderness were noted on examination. The laboratory results revealed that the liver enzymes were significantly high, with a positive mumps virus IgM serology test; the following conditions were excluded: hepatitis A, B, C, Epstein–Barr, and cytomegalovirus. The patient was treated conservatively through hydration maintenance, pain relief, and rest. Consistent with a self-limiting course of mumps associated with hepatitis, liver functions normalized over four weeks.</div></div><div><h3>Discussion</h3><div>Mumps virus is an RNA paramyxovirus that affects glandular tissues. Although rare, case reports suggest that transient hepatitis can result from direct viral invasion or immune-mediated injury. The diagnosis requires high clinical suspicion, as symptoms overlap with other causes of viral hepatitis. The main treatment focuses on providing constant supportive care, which is usually sufficient, and the prognosis tends to be favorable.</div></div><div><h3>Conclusion</h3><div>Hepatitis is a rare but possible complication of mumps, especially in patients who have elevated liver enzymes. This case serves as a reminder that all healthcare professionals must be vigilant in atypical presentations of mumps to guarantee appropriate treatment and avoid unnecessary tests.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02207"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mycotic cyst: Case report 真菌性囊肿1例。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02120

Oviya Selvam , Yogindher Singh R. , M.D. Gowthaman , Manobalan K. , K. Subashree

引用次数: 0

Disseminated Mycobacterium Chelonae infection in an immunocompromised adult: An uncommon etiology of skin infection 一名免疫力低下的成年人感染了散播的螯状分枝杆菌：一种不常见的皮肤感染病因。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02132

Biruk Amare, Andrew Mangano, Moumita Sarker, Sagun Adhikari

{"title":"Disseminated Mycobacterium Chelonae infection in an immunocompromised adult: An uncommon etiology of skin infection","authors":"Biruk Amare, Andrew Mangano, Moumita Sarker, Sagun Adhikari","doi":"10.1016/j.idcr.2024.e02132","DOIUrl":"10.1016/j.idcr.2024.e02132","url":null,"abstract":"<div><div><em>Mycobacterium Chelonae</em> is a rapidly growing nontuberculous mycobacterium (NTM) that is ubiquitous in the environment and is associated with skin and soft tissue infections (1). Because <em>Mycobacterium Chelonae</em> is an opportunistic infection, it can present as skin abscess, cellulitis, osteomyelitis, pulmonary infection or disseminated infections, particularly in individuals with compromised immune systems or underlying lung conditions such as cystic fibrosis or bronchiectasis. <em>M.Chelonae</em> is one of the most pathogenic rapidly growing mycobacteria (RGM). Diagnosing RGM and distinguishing it from Mycobacterium tuberculosis is important because public health tracking and management is different in these two organisms. Antibiotic susceptibility testing can also provide valuable clues to the species identification of RGM as each species has a specific in vitro antibiotic susceptibility pattern (2). Although incidence of <em>M. Chelonae</em> is increasing, these infections often remain misdiagnosed. This case report discusses the clinical presentation, diagnostic challenges, the rationale for early empiric treatment, and therapeutic options for <em>M. Chelonae</em> infection, emphasizing the importance of timely intervention in immunocompromised individuals.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02132"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scrub typhus associated with reactive arthritis: A case report and literature review

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02143

Shinya Yamanaka , Kazuhiro Ishikawa , Miyako Kon , Junko Aoki , Kunimichi Saeki , Junta Tanaka

{"title":"Scrub typhus associated with reactive arthritis: A case report and literature review","authors":"Shinya Yamanaka , Kazuhiro Ishikawa , Miyako Kon , Junko Aoki , Kunimichi Saeki , Junta Tanaka","doi":"10.1016/j.idcr.2024.e02143","DOIUrl":"10.1016/j.idcr.2024.e02143","url":null,"abstract":"<div><div>Scrub typhus (tsutsugamushi disease) is an acute febrile illness caused by <em>Orientia tsutsugamushi</em>, often found in Asia and Oceania. The presence of an eschar, characterized by a crust, is a key diagnostic finding. Many symptoms of this disease are already known, however reactive arthritis following scrub typhus is very rare. Here, we present a case of 79-year-old man who was referred to our hospital because of continuous fever and left shoulder pain. We found 4-fold rise in <em>Orientia tsutugamushi</em>-specific IgG titer using paired serum samples and <em>Orientia</em> sp. genes by real-time PCR from a crust of right thigh. And the left shoulder joint image was consistent with aseptic arthritis; thus we diagnosed as scrub typhus with reactive arthritis. This case highlights the importance of recognizing reactive arthritis as a symptom of scrub typhus. In this report, we also review published cases of reactive arthritis associated with scrub typhus, and we suppose that this arthritis related to this infection may recover after antibiotic use and have a good prognosis. Physicians' awareness of newly appeared arthritis may contribute to facilitate early diagnosis, and may improve the course of such patients.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02143"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive management of actinomycetoma in a young male: A case report from Somalia

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02141

Mohamed Adam Mahamud , Claude M. Muvunyi , Ayman Ahmed , Emmanuel Edwar Siddig

{"title":"Comprehensive management of actinomycetoma in a young male: A case report from Somalia","authors":"Mohamed Adam Mahamud , Claude M. Muvunyi , Ayman Ahmed , Emmanuel Edwar Siddig","doi":"10.1016/j.idcr.2024.e02141","DOIUrl":"10.1016/j.idcr.2024.e02141","url":null,"abstract":"<div><div>Mycetoma is a neglected tropical disease that predominantly affects individuals in low socioeconomic strata, primarily in tropical and subtropical regions. This case report describes a 20-year-old male student from Bahdo City, Somalia, who presented with a persistent cervical mass following a history of trauma. The patient exhibited vital signs within normal limits, and imaging studies, including ultrasound and computed tomography, revealed well-defined cystic masses. A Fine Needle Aspiration cytology confirmed the diagnosis of actinomycetoma by revealing sheets of neutrophils, multinucleated giant cells, and branching filamentous bacteria structures. The patient was treated with co-trimoxazole and amikacin, resulting in significant improvement after three months, highlighting the critical role of early diagnosis and appropriate medical management in enhancing patient outcomes. This report emphasizes the importance of thorough clinical evaluation and the use of cytological methods, particularly in resource-limited settings, to expedite the diagnosis and treatment of actinomycetoma.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02141"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histoplasmosis – More common than we realize

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02180

Ujjwayini Ray , Soma Dutta, Arpita Sutradhar

引用次数: 0

Pneumocystis pneumonia with multiple nodules on computed tomography

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02200

Saori Ikeda , Noriyo Yanagawa

引用次数: 0

Meningitis caused by Streptococcus pyogenes triggered by malignant otitis externa: A case report

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02214

Ayako Shirai , Daisuke Ono , Kazuyuki Mimura , Kei Yamamoto , Takayuki Kawamura , Yujin Nozaki , Sunao Tanaka , Masaomi Yamamoto , Hideaki Ohno , Kunihisa Tsukada , Hideaki Oka

{"title":"Meningitis caused by Streptococcus pyogenes triggered by malignant otitis externa: A case report","authors":"Ayako Shirai , Daisuke Ono , Kazuyuki Mimura , Kei Yamamoto , Takayuki Kawamura , Yujin Nozaki , Sunao Tanaka , Masaomi Yamamoto , Hideaki Ohno , Kunihisa Tsukada , Hideaki Oka","doi":"10.1016/j.idcr.2025.e02214","DOIUrl":"10.1016/j.idcr.2025.e02214","url":null,"abstract":"<div><div>A previously healthy 58-year-old male initially presented to a healthcare facility with otorrhea in his left ear, accompanied by a scab in both the auricle and ear canal, with a lesion protruding from the left cavity and oozing discharge (day 0). The following day, the patient was transferred to our facility with fever and altered consciousness. Imaging studies, including computed tomography and magnetic resonance imaging, revealed a soft tissue mass in the left maxillary, ethmoid and sphenoid sinuses, and diffuse pus within the subdural space over the bilateral frontoparietal regions. Cerebrospinal fluid (CSF) analysis showed elevated opening pressure, increased white blood cell count, predominance of polymorphonuclear leukocytes, elevated protein levels, and reduced glucose levels compared to the serum. <em>Streptococcus pyogenes</em> was identified in ear discharge, CSF, and blood cultures using matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The presence of a papilloma in the left nasal cavity suggested that malignant otitis externa (MOE) served as the entry point for infection, leading to meningitis. The patient was treated with a combination of ceftriaxone and vancomycin, followed by ceftriaxone and cefotaxime, surgical resection of the tumor, and local debridement for infection control. To date, this is the first reported case of <em>S. pyogenes</em>-induced meningitis secondary to MOE. Although rare, the detection of <em>S. pyogenes</em> in otitis externa emphasizes the necessity of comprehensive evaluation of ear pathology to enable effectively source control as well as manage related infections and complications.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02214"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe disseminated Talaromyces marneffei infection in idiopathic CD4 lymphopenia

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02148

Bingkun Li , Tiantian Li , Qian Lu , Dong Liang , Cunwei Cao

引用次数: 0

Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02167

Xin Xiang , Jian Zheng , Cheng-Wei Ma , Lei Ruan, Jing-Zheng Zhuang, Qing-Chun Li

引用次数: 0