{"title":"Ultrasound findings of Fitz-Hugh-Curtis Syndrome (FHCS) associated with splenic tuberculosis in an HIV-positive male patient","authors":"Ibrahima Niang , Daouda Thioub , Mamadou Ly , Abdourahmane Ndong , Fallou Galass Niang , Abdoulaye Dione Diop , Sokhna Ba","doi":"10.1016/j.idcr.2024.e02036","DOIUrl":"10.1016/j.idcr.2024.e02036","url":null,"abstract":"<div><p>Fitz-Hugh-Curtis (FHCS) is characterized by an inflammation of the hepatic capsule concomitant or following pelvic infection due to <em>Chlamydia trachomatis</em> or <em>Neisseria gonorrhea</em>. It is a rare condition occurring most often in a woman of childbearing age and very rare in male patients. Splenic involvement is also a rare form of abdominal tuberculosis. The association of these two conditions is very uncommon. We report the exceptional case of a 58- year-old HIV-positive male patient, with whom abdominal ultrasound helped diagnose FHCS associated with abdominal tuberculosis invovlving the spleen.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02036"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001124/pdfft?md5=a4fb7863f78bfd6f08eb04bfa5b99aec&pid=1-s2.0-S2214250924001124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141963007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02057
S. Jawad Zafar , Zachary Wynne , Thomas John , Lauren Groft Buzzalino , Akira A. Shishido , David J. Riedel
{"title":"Cefazolin-induced hemolytic anemia in septic arthritis: A case report","authors":"S. Jawad Zafar , Zachary Wynne , Thomas John , Lauren Groft Buzzalino , Akira A. Shishido , David J. Riedel","doi":"10.1016/j.idcr.2024.e02057","DOIUrl":"10.1016/j.idcr.2024.e02057","url":null,"abstract":"<div><p>A 50-year-old woman living with untreated HIV and injection drug use presented with right shoulder pain. The shoulder exam and computed tomography (CT) scan were concerning for septic arthritis. She was started on empiric vancomycin and cefepime and underwent right shoulder debridement and humeral head resection. Bone cultures grew methicillin sensitive <em>Staphylococcus aureus</em> (MSSA); empiric broad-spectrum antibiotics were changed to cefazolin. The patient subsequently developed severe anemia refractory to blood transfusions approximately 6 days later. Further evaluation disclosed hemolytic anemia attributable to cefazolin. Antibiotic therapy was switched from cefazolin to daptomycin, and the patient was started on prednisone. She had sustained improvement in hemoglobin values above 6 g/dL without requiring further transfusions prior to hospital discharge. Drug-induced immune hemolytic anemia from cefazolin is rare but has been reported primarily in the perioperative setting. Here, we present a case following initiation of treatment for septic arthritis.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02057"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001331/pdfft?md5=fc10850bc36aaf21a9b683eaecf81019&pid=1-s2.0-S2214250924001331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141985033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02115
S. Belmahi , A. Saddari , H. Zrouri , Y. Sbibih , C. Ben moussa , O. Abdesselami , K. Ghomari , I. Alla , S. Kaddouri , A. Idrissi , S. Ezrari , E. Benaissa , Y. Ben Lahlou , M. Elouenass , A. Maleb
{"title":"Wound infection with multidrug-resistant Providencia rettgeri: About a case report and littérature review","authors":"S. Belmahi , A. Saddari , H. Zrouri , Y. Sbibih , C. Ben moussa , O. Abdesselami , K. Ghomari , I. Alla , S. Kaddouri , A. Idrissi , S. Ezrari , E. Benaissa , Y. Ben Lahlou , M. Elouenass , A. Maleb","doi":"10.1016/j.idcr.2024.e02115","DOIUrl":"10.1016/j.idcr.2024.e02115","url":null,"abstract":"<div><h3>Introduction and importance</h3><div><em>Providencia rettgeri</em>, a member of the <em>Morganellaceae</em> family within the <em>Enterobacterales</em> order, is predominantly associated with urinary tract infections in hospitalized individuals, particularly those with indwelling urinary catheters. However, wound infections caused by <em>P. rettgeri</em> are exceedingly rare, with an estimated incidence of around 0.1 %. Here, we present a case of wound infection in a healthy child caused by <em>P. rettgeri</em>, highlighting the rarity of the organism and emphasizing the importance of prompte identification and appropriate antibiotic therapy.</div></div><div><h3>Case report</h3><div>A 4-year-old child presented with a soft tissue abscess in the left calf, following an injury sustained from a tree trunk a few days prior. The patient underwent wound debridement and abscess drainage, followed by empirical antibiotic therapy with amoxicillin and clavulanic acid. Bacteriological samples collected intraoperatively revealed colonies of <em>P. rettgeri,</em> identified with high certainty using the BD Phoenix™ 100 automated system. Antimicrobial susceptibility testing showed resistance to several antibiotics but sensitivity to third-generation cephalosporins, amikacin, and aztreonam. Antibiotic therapy was adjusted accordingly, leading to clinical improvement and discharge after ten days of hospitalization</div></div><div><h3>Discussion</h3><div><em>P. rettgeri</em>, a Gram-negative bacillus, is a rare causative agent of wound infections. While predominantly associated with nosocomial urinary tract infections, it can rarely lead to various other infections, including wound infections, particularly in hospitalized or immunocompromised individuals. Resistance to multiple antibiotics, including carbapenems, poses challenges in treatment selection.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of considering <em>P. rettgeri</em> as a potential pathogen in wound infections, even in healthy individuals. Awareness of its presence and antibiotic susceptibility patterns is crucial for appropriate management and prevention of complications. Further studies are warranted to elucidate the epidemiology and clinical significance of <em>P. rettgeri</em> infections in different patient populations.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"38 ","pages":"Article e02115"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02105
A.R. Buonomo , L. Cattaneo , G. Viceconte , F. Calabria , G. Di Troia , A. Di Fusco , J. Mula , A. Cozzolino , L. Ametrano , A. D’Avolio , I. Gentile
{"title":"Long-term oritavancin therapy for shoulder prosthetic joint infection: A case guided by therapeutic drug monitoring (TDM)","authors":"A.R. Buonomo , L. Cattaneo , G. Viceconte , F. Calabria , G. Di Troia , A. Di Fusco , J. Mula , A. Cozzolino , L. Ametrano , A. D’Avolio , I. Gentile","doi":"10.1016/j.idcr.2024.e02105","DOIUrl":"10.1016/j.idcr.2024.e02105","url":null,"abstract":"<div><div>Oritavancin is a novel long-acting lipoglycopeptide with in vitro activity against methicillin-resistant (MR) Gram-positive pathogens and a good bactericidal activity even in presence of biofilm forming bacteria. It has been approved for acute bacterial skin and skin structure infections (ABSSSI), but recent reports have demonstrated possible off-label uses, as for prosthetic joint infections (PJI), which, in more than half of cases, are caused by MR Gram positive organisms.</div><div>W<strong>e</strong> reported a case of a man in his eighties with a late shoulder PJI caused by methicillin resistant <em>Staphyloccus epidermidis</em> (MRSE) with contraindications for surgical replacement and few oral therapeutic options for a long term suppressive antibiotic therapy. The prosthesis was retained, and the patient received ten outpatient sequential doses of 1200 mg of oritavancin for 28 weeks, based on therapeutic drug monitoring (TDM) as a guide for correct timing of administration of each dose. During oritavancin administration, the patient achieved clinical cure, with disappearance of the pain and regaining pre-infection joint mobility, with no side effects reported and no further surgery or hospitalization needed. The treatment is ongoing as a long-lasting suppressive antimicrobial therapy. Oritavancin could represent an excellent solution for treating PJI caused by MR organism, especially in patients who need a long-term suppressive therapy.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"38 ","pages":"Article e02105"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142652532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02117
Yuanwen Chen , Yisheng Zhou , Zhibin Xu
{"title":"Concurrent Klebsiella pneumoniae liver abscess and infective endocarditis: A rare case report and literature review","authors":"Yuanwen Chen , Yisheng Zhou , Zhibin Xu","doi":"10.1016/j.idcr.2024.e02117","DOIUrl":"10.1016/j.idcr.2024.e02117","url":null,"abstract":"<div><h3>Background</h3><div>Investigating the clinical characteristics and treatment strategies of pyogenic liver abscess (PLA) complicated by infective endocarditis (IE), this study draws on a successfully treated case of PLA caused by Klebsiella pneumoniae, alongside a literature review of similar cases.</div></div><div><h3>Case Summary</h3><div>We report a 50-year-old male with type 2 diabetes who presented with acute fever, chills, and a liver abscess. The patient was initially treated with intravenous ceftriaxone (2 g daily). Due to the onset of septic shock, the antibiotic regimen was escalated to piperacillin-tazobactam (4.5 g every 8 h) and levofloxacin (0.5 g daily). Ultrasound-guided percutaneous drainage of the liver abscess was performed, and blood cultures confirmed <em>Klebsiella pneumoniae</em>. Upon the development of infective endocarditis, the treatment was adjusted to a combination of ceftriaxone and amikacin for one week, followed by six weeks of ceftriaxone monotherapy, resulting in full recovery.</div></div><div><h3>Conclusion</h3><div>This case report illustrates the rare association of Klebsiella pneumoniae-induced PLA with IE in a diabetic patient. It emphasizes the importance of individualized treatment strategies, with insights drawn from this case contributing to the understanding of managing such complex infections. While the successful outcome of this case provides valuable clinical insights, it highlights the need for careful consideration in treatment approaches. The findings from this single case should guide clinicians in similar scenarios but should not be generalized without further evidence.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"38 ","pages":"Article e02117"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02049
Adam Cewers , Torgny Sunnerhagen , Patrik Gilje , Fredrik Wannheden , Jonas Bläckberg , Per Wierup , Mårten Larsson , Magnus Rasmussen
{"title":"Even a single positive blood culture may matter – A case of prosthetic valve infective endocarditis caused by Corynebacterium kroppenstedtii","authors":"Adam Cewers , Torgny Sunnerhagen , Patrik Gilje , Fredrik Wannheden , Jonas Bläckberg , Per Wierup , Mårten Larsson , Magnus Rasmussen","doi":"10.1016/j.idcr.2024.e02049","DOIUrl":"10.1016/j.idcr.2024.e02049","url":null,"abstract":"<div><p><em>Corynebacterium</em> is a skin commensal bacterium that can contaminate blood cultures. It is however also a rare cause of infective endocarditis (IE). Here we report a case of <em>Corynebacterium kroppenstedtii</em> aortic prosthesis IE in a 76-year-old man where only a single blood culture bottle was positive initially. <em>C. kroppenstedtii</em> is a very rare cause of IE, only reported two times previously. The diagnosis in our case was confirmed by repeated blood culture positivity and eventually by detection of DNA from <em>C. kroppenstedtii</em> on heart valves after valve exchange surgery. At surgery an aortic root abscess was detected and the valve was replaced by a homograft. Recovery was complicated by antibiotic-induced nephrotoxicity and treatment was concluded with moxifloxacin in combination with rifampicin. Recovery was uneventful. This case demonstrates that growth in even a single blood culture bottle may be important in patients with prosthetic heart valves.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02049"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001252/pdfft?md5=a4b5a56a62d82aa038dbdb247a4c5abc&pid=1-s2.0-S2214250924001252-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02039
Md. Mehedi Hasan, Fariha Fairouz, Amit Banik, Md. Jubaidul Islam, Jamal Uddin Ahmed
{"title":"Salmonella infective endocarditis in a young diabetic lady with device closure of PDA and VSD: A rare case report","authors":"Md. Mehedi Hasan, Fariha Fairouz, Amit Banik, Md. Jubaidul Islam, Jamal Uddin Ahmed","doi":"10.1016/j.idcr.2024.e02039","DOIUrl":"10.1016/j.idcr.2024.e02039","url":null,"abstract":"<div><p>The risk of infective endocarditis remains a major concern in patients with congenital heart disease; nevertheless, use of devices and prostheses in corrective surgery may have contributed to an increased incidence. Infective endocarditis due to Salmonella species are infrequently reported, therefore, their clinical presentations, prognosis and optimal treatment guideline are poorly described in literature. Here, we report a case of an 18-year-old diabetic lady with history of device closure of Patent ductus arteriosus and closure of peri-membranous small Ventricular septal defect in the year of 2005 and 2018 respectively who presented to us with high-grade fever for 10 days without any focal symptom. She was initially diagnosed as a case of Enteric fever based on serological tests for Salmonella species, later Transesophageal echocardiography confirmed infective endocarditis. The patient was treated with combination of antibiotics for a total 6-week duration. Although very rare, Salmonella have a predilection for the heart valves, particularly mitral and aortic valves. Diagnosis may be difficult, blood culture is often negative and a Transesophageal echocardiography should be performed without delay particularly in high risk patients. In most cases Salmonella endocarditis can be successfully treated with antimicrobials alone<em>.</em></p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02039"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221425092400115X/pdfft?md5=1ea3c31bf7ad0c2f9c078e9c8195e60a&pid=1-s2.0-S221425092400115X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02053
Helene G. Meyer , Balthasar L. Hug
{"title":"Aerococcus urinae endocarditis – A case report.","authors":"Helene G. Meyer , Balthasar L. Hug","doi":"10.1016/j.idcr.2024.e02053","DOIUrl":"10.1016/j.idcr.2024.e02053","url":null,"abstract":"<div><p><em>Aerococcus urinae</em> is a gram-positive coccus bacterium with a previously underestimated prevalence due to morphological similarities to other gram-positive cocci. Development of newer diagnostic technologies (such as matrix-assisted laser desorption ionization time-of-flight mass spectrometry MALDI-TOF) led to increased recognition of <em>Aerococcus urinae</em> as causative organism mainly for urinary tract infections. Its antibiotic susceptibility poses some challenges, with resistance to some drugs of choice for urinary tract infection. We report a case of a 69-year-old male with infective endocarditis of the mitral valve, who initially presented with fever and shoulder pain to the emergency department. The patient reported an episode of obstructive renal infection two weeks earlier, which was treated with trimethoprim-sulfamethoxazole. The unusual presentation with shoulder pain and a new heart murmur led to suspicion of endocarditis. Urine and blood cultures were positive for <em>Aerococcus urinae</em>, echocardiography revealed vegetations on the mitral valve with severe mitral insufficiency. After two weeks of antibiotic treatment, mitral valve replacement was performed, from which the patient recovered. Reports of <em>Aerococcus urinae</em> endocarditis are still limited in number. On the other side, <em>Aerococcus urinae</em> is an emerging bacterial uropathogen with greater relevance than previously believed. We review the case reports of <em>Aerococcus urinae</em> endocarditis and newest literature about its presentation, course, and clinical management.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02053"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221425092400129X/pdfft?md5=3cdc09a7abc3a2d193b5f319fc6ee689&pid=1-s2.0-S221425092400129X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141952607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02055
Mohammad Mehdi Sabahi , Mehrdad Mosadegh , Azin Kazemi , Razieh Amini , Shahab Mahmoudvand , Mojtaba Hedayat Yaghoubi , Mohammad Masoud Maleki , Zahra Sanaei , Farid Azizi Jalilian
{"title":"Parvovirus B19 and Parvovirus 4 infections among healthy blood donors; A prevalence report from Iran","authors":"Mohammad Mehdi Sabahi , Mehrdad Mosadegh , Azin Kazemi , Razieh Amini , Shahab Mahmoudvand , Mojtaba Hedayat Yaghoubi , Mohammad Masoud Maleki , Zahra Sanaei , Farid Azizi Jalilian","doi":"10.1016/j.idcr.2024.e02055","DOIUrl":"10.1016/j.idcr.2024.e02055","url":null,"abstract":"<div><h3>Background</h3><p>Parvoviruses, characterized by their tropism for blood cells, can manifest as asymptomatic infections. With their ability to persist in blood, assessing the prevalence of Parvovirus B19 (B19V) and Parvovirus 4 (PARV4) among healthy blood donors is essential for evaluating the potential transmission risks through blood transfusions, emphasizing the need for comprehensive screening protocols.</p></div><div><h3>Methods</h3><p>Four hundred blood donors participated in the study, with their blood specimens subjected to Real-Time PCR analysis for B19V and PARV4 nucleic acids after obtaining informed consent. Additionally, Complete Blood Count (CBC) assessments and determination of anti-B19 V-IgM and anti-B19 V-IgG antibody titers were performed using Enzyme-Linked Immunosorbent Assay (ELISA) for all collected samples.</p></div><div><h3>Results</h3><p>The results reveal that 12 out of 400 individuals (3 %) exhibited positive results for B19V DNA, while 6 out of 400 individuals (1.5 %) tested positive for PARV4 DNA. Additionally, 8 out of 400 individuals (2 %) displayed positive results for anti-B19V IgM, and 306 out of 400 individuals (76.5 %) exhibited positive results for anti-B19 IgG. Notably, one donation from a donor presenting anti-IgM antibodies was subsequently confirmed as B19V DNA-positive through Real-Time PCR. In the analysis of CBC, a significant disparity in platelet levels was observed between B19V-positive donors, PARV4-positive donors, and B19V-negative donors.</p></div><div><h3>Conclusions</h3><p>The study suggests that individuals at high risk, lacking detectable B19V antibodies, should undergo systematic screening and exclusion. This precaution is intended to minimize potential contamination risks within the studied cohort, despite the undefined pathogenesis and clinical implications of PARV4.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02055"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001318/pdfft?md5=0ba6a3d7da2b6a5263e09bccc294ab83&pid=1-s2.0-S2214250924001318-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141953361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01968
Ashton D. Hall , Laura Victoria Medina Rodriguez , Jared Vearrier , Kavya Patel , Bryan C. Hambley , Moises A. Huaman
{"title":"The great imitator: Tuberculosis with lymphadenopathy and splenomegaly","authors":"Ashton D. Hall , Laura Victoria Medina Rodriguez , Jared Vearrier , Kavya Patel , Bryan C. Hambley , Moises A. Huaman","doi":"10.1016/j.idcr.2024.e01968","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01968","url":null,"abstract":"<div><p>Tuberculosis (TB) is a leading infectious killer worldwide. Over two-thirds of new TB diagnoses in the United States occur among first-generation immigrants, especially within a year of migration. Hodgkin lymphoma (HL) accounts for a minority of lymphoma cases but presents similarly to disseminated or extrapulmonary TB. Clinical overlap between TB and HL increases patient risk of misdiagnosis. Concomitant presentation of both diseases is not uncommon but infrequently reported. We present a case of isoniazid-resistant TB with progressively worsening lymphadenopathy and splenomegaly despite appropriate TB treatment. The patient was diagnosed with HL following PET/CT and axillary lymph node biopsy.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01968"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000441/pdfft?md5=bd3ca549060c8ac8c507148049fda40e&pid=1-s2.0-S2214250924000441-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140607080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}