IDCases最新文献_第3页

A case of disseminated blastomycosis in New England 新英格兰播散性芽孢菌病1例。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02139

Cole Royer , Matthew Owens , Kenrick Wysong , Michael Madrid , Katrina Moreau

{"title":"A case of disseminated blastomycosis in New England","authors":"Cole Royer , Matthew Owens , Kenrick Wysong , Michael Madrid , Katrina Moreau","doi":"10.1016/j.idcr.2024.e02139","DOIUrl":"10.1016/j.idcr.2024.e02139","url":null,"abstract":"<div><div><em>Blastomyces</em> infections are classified as dimorphic fungal infections commonly seen geographically throughout the Mississippi and Ohio River Valleys, St. Laurence Seaways, as well as the Canadian providences of Ontario Manitoba, and Saskatchewan. Although primarily endemic in the Midwestern United States, there has been a rise in cases throughout New England. Factors that could contribute to this rise of blastomycosis include a changing climate, increasing use of immunosuppressive medications as well as a greater recognition of this disease. Initial presentation of blastomycosis follows the inhalation of fungal spores which can cause flu-like symptoms or mimic acute pneumonia. Blastomycosis can also present as a disseminated infection through extrapulmonary spread in both immunocompromised and immunocompetent hosts and cases present at similar rates within the population. Here we present a case of disseminated blastomycosis in a patient from New England with no reported pre-existing risk factors. The patient developed blastomycosis osteomyelitis in the left elbow which prompted surgical intervention as well as a 12-month regimen of voriconazole therapy. This case outlines the need to adopt better surveillance practices for blastomycosis in non-endemic areas as well as highlights the imperative role of healthcare staff in implementing proper reporting measures to track the spread of blastomycosis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02139"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Babesiosis with low parasitemia as a cause of secondary hemophagocytic lymphohistiocytosis in a previously healthy adult 低寄生虫血症的巴贝斯虫病是先前健康成人继发性噬血细胞性淋巴组织细胞增多症的原因

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02172

Max W. Jacobs , Joseph M. Rocco , Lisa K. Andersen , Thomas E. Robertson

引用次数: 0

Acute peritonitis secondary to spontaneous rupture of hepatic hydatid cyst: A case report and literature review 肝包虫囊肿自发性破裂继发急性腹膜炎1例并文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02166

Imen Ben Ismail , Elmontassar Belleh Zaafouri, Hakim Zenaidi, Saber Rebii, Ayoub Zoghlami

{"title":"Acute peritonitis secondary to spontaneous rupture of hepatic hydatid cyst: A case report and literature review","authors":"Imen Ben Ismail , Elmontassar Belleh Zaafouri, Hakim Zenaidi, Saber Rebii, Ayoub Zoghlami","doi":"10.1016/j.idcr.2025.e02166","DOIUrl":"10.1016/j.idcr.2025.e02166","url":null,"abstract":"<div><div>Spontaneous intraperitoneal rupture of hepatic hydatid cysts is a rare but serious complication that can lead to significant morbidity and mortality due to risks such as anaphylactic shock and secondary peritoneal hydatidosis. This report presents the case of a 59-year-old male farmer from a rural area of Tunisia who presented with severe abdominal pain, nausea, and vomiting. Diagnostic imaging revealed a large hepatic cyst with free peritoneal fluid, indicating a ruptured hydatid cyst. Emergency surgery involved cyst evacuation, peritoneal lavage, and drainage. Postoperatively, the patient developed a transient biliary fistula but recovered well with albendazole therapy to prevent recurrence. Six months post-surgery, the patient remains asymptomatic. The case underscores the importance of considering hydatid disease in acute abdomen diagnoses in endemic regions and highlights the critical role of imaging and timely surgical intervention. The literature review indicates variability in the prevalence of cyst rupture and emphasizes the need for a comprehensive approach combining surgery and antiparasitic treatment for effective management and recurrence prevention.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02166"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A complicated case of refractory multiple drug-resistant peritoneal dialysis-associated peritonitis due to teratoma 畸胎瘤致难治性多重耐药腹膜透析相关性腹膜炎的复杂病例

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02209

Li-Yan Mao , Yi Tang , Juan Yang

引用次数: 0

Early diagnosis of progressive multifocal leukoencephalopathy in untreated HIV infection via ultrasensitive PCR testing for JC virus: A case report JC病毒超敏PCR检测早期诊断未经治疗的HIV感染者进行性多灶性脑白质病1例

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02229

Kenji Nakano , Akira Kawashima , Takato Nakamoto , Kazuo Nakamichi , Ryo Kuwata , Seitaro Abe , Eri Inoue , Naokatsu Ando , Haruka Uemura , Daisuke Mizushima , Takahiro Aoki , Katsuji Teruya , Hiroyuki Gatanaga

{"title":"Early diagnosis of progressive multifocal leukoencephalopathy in untreated HIV infection via ultrasensitive PCR testing for JC virus: A case report","authors":"Kenji Nakano , Akira Kawashima , Takato Nakamoto , Kazuo Nakamichi , Ryo Kuwata , Seitaro Abe , Eri Inoue , Naokatsu Ando , Haruka Uemura , Daisuke Mizushima , Takahiro Aoki , Katsuji Teruya , Hiroyuki Gatanaga","doi":"10.1016/j.idcr.2025.e02229","DOIUrl":"10.1016/j.idcr.2025.e02229","url":null,"abstract":"<div><div>Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease triggered by the reactivation of JC virus (JCV) in individuals with immunodeficiency, particularly those with untreated human immunodeficiency virus (HIV) infection. This case report describes a 46-year-old HIV-positive man who initially presented with neurological symptoms and was incorrectly diagnosed as cerebral infarction. Although standard real-time polymerase chain reaction (PCR) testing for JCV in cerebrospinal fluid (CSF) at a commercial laboratory was negative, neuroimaging and clinical suspicion prompted ultrasensitive PCR testing at a national laboratory. This test detected a low viral load of JCV (28 copies/mL), confirming the diagnosis of PML. The patient underwent treatment with antiretroviral therapy and corticosteroids to prevent immune reconstitution inflammatory syndrome; however, his neurological symptoms persisted. This case highlights the importance of ultrasensitive CSF JCV testing for early PML diagnosis when standard PCR tests are inconclusive, particularly in HIV patients with atypically low JCV levels. It also highlights the diagnostic challenges of PML and emphasizes the clinical value of advanced PCR techniques for timely and accurate diagnosis in similar cases.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02229"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skull bone lytic lesions: A rare form of multifocal skeletal tuberculosis 颅骨溶解性病变：一种罕见的多灶性骨结核

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02228

Nazmun Naher, Chowdhury Adnan Sami, Md Mizanur Rahman Khan, Shohael Mahmud Arafat, Abed Hussain Khan

{"title":"Skull bone lytic lesions: A rare form of multifocal skeletal tuberculosis","authors":"Nazmun Naher, Chowdhury Adnan Sami, Md Mizanur Rahman Khan, Shohael Mahmud Arafat, Abed Hussain Khan","doi":"10.1016/j.idcr.2025.e02228","DOIUrl":"10.1016/j.idcr.2025.e02228","url":null,"abstract":"<div><div>Tuberculosis (TB) is a complex disease that can mimic numerous diseases involving different organ systems, making diagnosing TB challenging. Multifocal tubercular osteomyelitis is a rare form of skeletal TB that represents only a minority of all skeletal TB cases. Our patient, a 24-year-old immunocompetent male, complained of a low-grade fever that rises in the evening, scalp aches, right-sided chest pain, and non-inflammatory back pain with rest pain for six months. He had lost six kilograms over this period of illness. He was anemic, with mildly tender swelling in the right parietal region of the scalp. Diffuse tenderness was present over the dorsal spine and right side of the chest, with no evidence of gibbus. Multifocal skeletal tuberculosis was diagnosed based on the presence of lytic lesions in the skull, ribs, and vertebrae, along with high erythrocyte sedimentation rate and high tracer uptake on a bone scan, with a biopsy report showing a granulomatous lesion from the vertebra. After six months of anti-TB therapy, during a scheduled follow-up visit, the patient showed significant improvement in pain and general well-being, with an improvement of the skull lytic lesion on the x-ray. Multifocal tubercular osteomyelitis is rare in immunocompetent males without pulmonary involvement. Early recognition and subsequent treatment could prevent severe complications from bone destruction in these cases.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02228"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tropheryma whipplei infection presenting as indolent endophthalmitis 乳头状瘤感染表现为眼内炎

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02178

Rami Waked , Jeffrey K. Moore , Brandon Winward , Sophia Ham , Howard W. Hoyt , Leyla Azis

{"title":"Tropheryma whipplei infection presenting as indolent endophthalmitis","authors":"Rami Waked , Jeffrey K. Moore , Brandon Winward , Sophia Ham , Howard W. Hoyt , Leyla Azis","doi":"10.1016/j.idcr.2025.e02178","DOIUrl":"10.1016/j.idcr.2025.e02178","url":null,"abstract":"<div><div><em>Tropheryma whipplei</em> (<em>T. whipplei</em>) infection can be difficult to diagnose due to its variable clinical manifestations and the limitations of standard diagnostic tests. This case describes a 78-year-old male with blurry vision and floaters in his right eye five months after cataract surgery, along with new onset weight loss and arthralgias. Ophthalmologic examination revealed inflammation and posterior vitritis, and vitreous biopsy identified <em>T. whipplei</em> via broad-range bacterial PCR, despite negative vitreous cultures and unremarkable flow cytometry. Gastrointestinal endoscopic and cerebrospinal fluid studies revealed no pathological or molecular evidence of the disease, complicating the diagnosis. Treatment with intravenous ceftriaxone followed by oral trimethoprim-sulfamethoxazole for 12 months resulted in resolution of symptoms and inflammation, with normalization of laboratory markers. This case underscores the diagnostic utility of broad-range bacterial PCR in atypical infections and highlights Whipple infection as a differential diagnosis in ocular presentations. Comprehensive interdisciplinary evaluation was critical for effective management.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02178"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous anthrax rapidly progressed into septic anthrax resulting in death – A case report 皮肤炭疽迅速发展为脓毒性炭疽导致死亡1例报告

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02216

Yufei Lyu , Shiyuan Li , Dongshu Wang , Meijie Feng , Wenjun Li , Xiankai Liu , Jia Zhou , Li Nie , Chao Pan , Shujuan Yu , Yan Guo , Hua Shao

引用次数: 0

Black tongue caused by linezolid in children: One case report and literature review 利奈唑胺致儿童黑舌1例报告并文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02181

Chunyu Zhang , Hongxia Shen , Jing Zhang , Lujie Xu , Meixing Yan , Chang Liu

引用次数: 0

Isolated tuberculoma involving multiple paranasal sinuses with aggressive features in an immunocompetent individual masquerading as a malignant neoplasm: A rarity unveiled with review of literature 孤立性结核瘤累及多个副鼻窦，具有侵袭性特征，免疫功能正常的个体伪装成恶性肿瘤：罕见的发现与文献回顾

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02179

Shaivy Malik , Rajat , Charanjeet Ahluwalia

{"title":"Isolated tuberculoma involving multiple paranasal sinuses with aggressive features in an immunocompetent individual masquerading as a malignant neoplasm: A rarity unveiled with review of literature","authors":"Shaivy Malik , Rajat , Charanjeet Ahluwalia","doi":"10.1016/j.idcr.2025.e02179","DOIUrl":"10.1016/j.idcr.2025.e02179","url":null,"abstract":"<div><div>Isolated primary tuberculoma of the paranasal sinuses is an exceedingly rare form of extra-pulmonary tuberculosis (EPTB), particularly in immunocompetent individuals. Its presentation is often atypical, mimicking aggressive neoplasms due to features such as local bone destruction, which complicates diagnosis and may lead to unnecessary invasive interventions. We report the case of a 32-year-old immunocompetent male presenting with chronic right nasal obstruction, rhinorrhoea, facial puffiness, hyposmia, and intermittent fever. Imaging revealed a heterogeneous mass in the right frontal, ethmoidal, and maxillary sinuses, with extensive bony erosion suggestive of a malignant etiology. Histopathological examination of biopsy tissue, however, demonstrated granulomatous inflammation with Langhans giant cells, necrosis, and acid-fast bacilli on Ziehl-Neelsen staining, confirming tuberculoma. Anti-tubercular treatment (ATT) was promptly initiated post-biopsy, leading to complete symptom resolution and no recurrence. This case sheds light on the importance of including tuberculoma in the differential diagnosis of aggressive sinonasal lesions in immunocompetent patients despite their rarity, and highlights the critical role of histopathology and ATT in effective management, potentially preventing extensive surgical resections and associated morbidity.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02179"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0