ARYA Atherosclerosis最新文献_第3页

In-hospital mortality of acute ST-elevation myocardial infarction (STEMI) and its predictors-using Yazd Cardiovascular Diseases Registry, YCDR.

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42893.2985

Mohsen Mohammadi, Seyedeh Mahdieh Namayandeh, Masoud Mirzaei, Mohsen Askari Shahi, Seyed Mahmoud Sadr Bafighi, Hamidreza Dehghan

{"title":"In-hospital mortality of acute ST-elevation myocardial infarction (STEMI) and its predictors-using Yazd Cardiovascular Diseases Registry, YCDR.","authors":"Mohsen Mohammadi, Seyedeh Mahdieh Namayandeh, Masoud Mirzaei, Mohsen Askari Shahi, Seyed Mahmoud Sadr Bafighi, Hamidreza Dehghan","doi":"10.48305/arya.2024.42893.2985","DOIUrl":"10.48305/arya.2024.42893.2985","url":null,"abstract":"Background: The purpose of this study was estimate and identify in hospital mortality predictors factors for patients with acute ST elevation myocardial infarction (STEMI).Methods: This study is a retrospective cohort study based on data from the Yazd Cardiovascular Diseases Registry (YCDR) from 2015-2018 in Yazd Province, Iran, focusing on hospitalized patients with ST-elevation myocardial infarction (STEMI). The primary outcome was in-hospital mortality in STEMI patients. A total of 1861 patients with STEMI were analyzed. Multivariable logistic regression was used to determine death predictive factors for in-hospital mortality in STEMI patients. The significance level of the model was considered to be 5% and the software was used for analysis.Results: The study included 1,861 patients with STEMI. Among them, 103 (5.5%) individuals died during admission the hospital. After multivariable logistic regression, the following variables were identified as death predictive factors for in-hospital mortality of STEMI: having a history of CVA (OR: 5.6, 95% CI: 2.2-20.3), killip class IV (OR: 6.4, 95%CI: 1.5-11.2), lower ejection fraction (OR: 3.6, 95% CI: 1.2-9.8), lower HDL cholesterol (OR: 1.2, 95% CI: 1.01-2.3), and lower hemoglobin (OR: 1.4, 95% CI: 1.3-2.9).Conclusion: This study found that lower ejection fraction, lower hemoglobin levels, Killip class IV, having a history of CVA, and low HDL cholesterol levels are important death predictive factors for hospital mortality in patients with STEMI. Health policy in STEMI management must consider these factors to improve hospital prognosis.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 6","pages":"6-16"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Importance of ECG findings in COVID-19 patients: Predictor of in-hospital prognosis. COVID-19 患者心电图结果的重要性：院内预后的预测因素。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2023.41600.2887

Mahsa Behnemoon, Mojhdeh Mehrno, Vahid Alinejad

{"title":"Importance of ECG findings in COVID-19 patients: Predictor of in-hospital prognosis.","authors":"Mahsa Behnemoon, Mojhdeh Mehrno, Vahid Alinejad","doi":"10.48305/arya.2023.41600.2887","DOIUrl":"10.48305/arya.2023.41600.2887","url":null,"abstract":"Background: Cardiac injury in COVID-19 patients confers a worse prognosis. The interpretation of electrocardiography can be beneficial in the early diagnosis of probable cardiac involvement. After adjusting for other variables, we sought to determine if the initial ECG on admission could add additional prognostic value.Methods: In this single-center cross-sectional study, 1165 patients with a positive COVID-19 PCR between Feb 2020 and Nov 2021 were enrolled in our study. Patients were grouped according to their admitted units, and survivors to hospital discharge or non-survivors. Predictors of ICU admission and in-hospital mortality were determined using univariate analysis and a logistic regression model.Results: The mean age was 55.6 ± 16.2 years and 52% were male. Out of 1165 patients, 149 deaths (12.8%) were recorded during hospitalization. Sinus tachycardia was the most common dysrhythmia, followed by premature atrial and ventricular beats, sinus bradycardia, and atrial fibrillation (28.6%, 5.6%, 3.9%, and 2.1%, respectively). Age (p<0.001), sex (p=0.006), history of diabetes mellitus (p=0.002), hypertension (p=0.018), ischemic heart disease (p=0.004), and cancer (p<0.001) were more frequent among non-survivors. Among ECG findings, tachycardia, low voltage QRS, ST-T changes, and dysrhythmia were related to an increased mortality risk. However, in regression analysis, only sex (OR 1.89, 95% CI 1.2 to 2.9, p=0.004), age (OR 1.03, 95% CI 1.02 to 1.05, p<0.001), and initial tachycardia (OR 1.02, 95% CI 1.01 to 1.03, p<0.001) were independent predictors of in-hospital mortality.Conclusion: Our data suggest that initial electrocardiographic findings could be helpful in distinguishing patients with an increased risk for ICU admission or in-hospital death.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 1","pages":"41-50"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142009663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platelet-enriched microRNAs as novel biomarkers in atherosclerotic and cardiovascular disease patients. 血小板富集microrna作为动脉粥样硬化和心血管疾病患者的新生物标志物。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.41664.2898

Parisa Masoudikabir, Mohammadreza Shirazy, Fatemeh Sigarchian Taghizadeh, Mohamad Esmail Gheydari, Mohsen Hamidpour

{"title":"Platelet-enriched microRNAs as novel biomarkers in atherosclerotic and cardiovascular disease patients.","authors":"Parisa Masoudikabir, Mohammadreza Shirazy, Fatemeh Sigarchian Taghizadeh, Mohamad Esmail Gheydari, Mohsen Hamidpour","doi":"10.48305/arya.2024.41664.2898","DOIUrl":"10.48305/arya.2024.41664.2898","url":null,"abstract":"Background: Cardiovascular disease (CVD) is a global health challenge. Various studies have shown that genetic and environmental factors play roles in the development and progression of CVD. Small non-coding RNAs, namely microRNAs (miRs), regulate gene expression and have key roles in essential cellular processes such as apoptosis, cell cycle, differentiation, and proliferation. Currently, clinical studies highlight the critical role of platelets and miRs in coronary thrombosis, atherosclerosis, and CVD.Methods: Using search engines such as PubMed and Scopus, articles studying platelet miRs and their effects on atherosclerosis and cardiovascular disease were reviewed.Results: This article presents a comprehensive analysis of the association of platelet-related miRs as prognostic, diagnostic, and therapeutic biomarkers with the pathogenesis of atherosclerosis and cardiovascular disease.Conclusion: Taken together, data show that platelet-related miRs not only play important roles in the initial development of atherosclerosis and cardiovascular disease (CVD), but they are also considered prognostic and diagnostic biomarkers in CVD.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 4","pages":"47-67"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and efficacy of mobile application to improve medication adherence for persons with cardiac disease. 提高心脏病患者服药依从性的移动应用程序的开发和疗效。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42169.2924

Raziyeh Ghafouri, Roxana Karbaschi, AliReza Mashhadi Hosein, Shakila Sharifian

{"title":"Development and efficacy of mobile application to improve medication adherence for persons with cardiac disease.","authors":"Raziyeh Ghafouri, Roxana Karbaschi, AliReza Mashhadi Hosein, Shakila Sharifian","doi":"10.48305/arya.2024.42169.2924","DOIUrl":"10.48305/arya.2024.42169.2924","url":null,"abstract":"Background: Patients with cardiovascular disease need to adhere to their treatment and care recommendations to prevent the progression of their condition and improve their quality of life. In this regard, this study was conducted to develop a mobile application and test its effectiveness in improving medication adherence among persons with cardiac disease.Methods: The study was conducted in two stages. The first stage involved the preparation of the \"Mobile Application for Persons with Cardiac Disease\" using the cascade model. In the second stage, 121 patients who were hospitalized in the cardiac intensive care unit of Ayatollah Taleghani Medical Education Center of Tehran from March to August 2023 were enrolled. The participants were randomly assigned to either the control group (63 people) or the intervention group (58 people). The study collected data using a medication adherence questionnaire on the 7th, 14th, and 21st day after discharge and compared the results with the control group. The data were analyzed using SPSS 20.Results: The average age of the control group was 56.75 ± 11.38 years, and the average age of the intervention group was 57.03 ± 11.55 years. The comparison of the average medication adherence with independent t-tests showed a significant difference between the intervention and control groups on the 7th, 14th, and 21st day after discharge (P<0.01). The results of the repeated measures test in each group also showed that the difference between the groups increased over time (P<0.001).Conclusion: The results of the study showed that the mobile application is effective in improving medication adherence among heart patients.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"28-36"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical performance and safety of the Vector® percutaneous transluminal coronary angioplasty balloon catheter: A single-arm, multicenter, retrospective post-marketing clinical study.

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42702.2971

Preeti Vani, Arvind Patel, Kumar Abhishek, Kailash Goyal

{"title":"Clinical performance and safety of the Vector® percutaneous transluminal coronary angioplasty balloon catheter: A single-arm, multicenter, retrospective post-marketing clinical study.","authors":"Preeti Vani, Arvind Patel, Kumar Abhishek, Kailash Goyal","doi":"10.48305/arya.2024.42702.2971","DOIUrl":"10.48305/arya.2024.42702.2971","url":null,"abstract":"Background: The present post-marketing clinical study was conducted over a 12-month follow-up period to monitor the clinical outcomes of patients treated with the Vector® Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter for the dilatation of coronary lesions. The semi-compliant balloon improves balloon-to-vessel wall apposition and minimizes balloon slippage during PTCA, which could reduce complications and improve clinical outcomes. This investigation aimed to assess the safety and effectiveness of the Vector® PTCA Balloon Catheter in real-world settings.Methods: A retrospective study was conducted to investigate the safety and efficacy of the Vector® PTCA Balloon Catheter in 125 patients who underwent pre-dilatation and post-dilatation. The primary outcome of the study was major adverse cardiac events (MACE), a composite endpoint encompassing target-lesion revascularization (TLR), cardiac death, and myocardial infarction (MI).Results: The Vector® PTCA Balloon Catheter has shown promising results in a small group of patients undergoing dilatation of normal and intricate coronary artery lesions, reflecting a 100% procedural success rate. The successful delivery to the target lesion, deployment, and subsequent retrieval of the device during the index procedure led to a 100% device success rate without any technical issues. A total of 3.2% (4) patients experienced MACE during the 12-month follow-up, with 1.6% (2) MI, 1.6% (2) TLR, and no cardiovascular deaths..Conclusion: This study demonstrated the favorable safety and reliability of the Vector® PTCA Balloon Catheter in patients with angina, MI, and a history of coronary artery disease in a real-world setting.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 6","pages":"17-26"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the impact of bioenergy economy-based health improvement (BEHI) as a mind-body intervention on laboratory, clinical and psychological factors in post-MI patients: A randomized controlled trial. 评估基于生物能源经济的健康改善（BEHI）作为心身干预对心肌梗死后患者实验室、临床和心理因素的影响：一项随机对照试验

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2023.41115.2847

Mahboubeh Farzanegan, Marsa Sadat Hashemi Jazi, Afsoon Derakhshan Jan, Masoumeh Sadeghi, Hamidreza Roohafza

{"title":"Evaluating the impact of bioenergy economy-based health improvement (BEHI) as a mind-body intervention on laboratory, clinical and psychological factors in post-MI patients: A randomized controlled trial.","authors":"Mahboubeh Farzanegan, Marsa Sadat Hashemi Jazi, Afsoon Derakhshan Jan, Masoumeh Sadeghi, Hamidreza Roohafza","doi":"10.48305/arya.2023.41115.2847","DOIUrl":"10.48305/arya.2023.41115.2847","url":null,"abstract":"Background: Patients with ischemic heart disease often exhibit various psychological factors that increase the risk of future cardiovascular events. Therefore, in addition to rehabilitation programs, there is a need for more interventional psychotherapy. Bioenergy Economy-based Health Improvement (BEHI) is a mind-body intervention that may address these issues. This study aimed to evaluate the effectiveness of the BEHI program on laboratory, clinical, and psychological factors in post-myocardial infarction (MI) patients.Methods: In this study, 52 post-MI patients were randomly divided into two groups. One group received cardiac rehabilitation combined with the BEHI program, while the other group received only cardiac rehabilitation. Laboratory data, clinical characteristics, and psychological variables were evaluated at baseline, immediately after the intervention, and four months post-intervention (follow-up).Results: Among the participants, the mean age was 59.97 ± 6.32 years, and 98.07% were male. The results showed a significant improvement in the mean scores of metabolic equivalents (METs), depression, and anxiety in participants who received the BEHI program and the rehabilitation program (p values: 0.006, 0.038, and 0.028, respectively).Conclusion: These findings suggest that incorporating mind-body interventions like the BEHI program into cardiac rehabilitation can enhance physical and psychological outcomes for patients recovering from MI.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 4","pages":"14-22"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term and long-term clinical outcomes of percutaneous coronary intervention on saphenous vein grafts. 经皮冠状动脉介入治疗隐静脉移植物的近期和长期临床效果。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.41338.2867

Salman Nikfarjam, Arsalan Salari, Fardin Mirbolouk, Aseme Pourrajabi, Mohammad Ghasemi, Seyed Amir Ghadiri Asli, Seyedeh Behnaz Masoum Zadeh Kiaee, Seyed Aboozar Fakhr-Mousavi, Mohammad Ebrahim Ghafari

{"title":"Short-term and long-term clinical outcomes of percutaneous coronary intervention on saphenous vein grafts.","authors":"Salman Nikfarjam, Arsalan Salari, Fardin Mirbolouk, Aseme Pourrajabi, Mohammad Ghasemi, Seyed Amir Ghadiri Asli, Seyedeh Behnaz Masoum Zadeh Kiaee, Seyed Aboozar Fakhr-Mousavi, Mohammad Ebrahim Ghafari","doi":"10.48305/arya.2024.41338.2867","DOIUrl":"10.48305/arya.2024.41338.2867","url":null,"abstract":"Background: Ischemic heart disease (IHD) is the leading cause of 16% of deaths globally. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are the main treatment options. Saphenous vein grafts (SVGs) remain the most frequently used conduits for CABG. In addition, PCI in cases previously undergoing CABG is related to worse long-term outcomes. This study aimed to evaluate PCI's short-term and long-term clinical outcomes on SVGs.Methods: Sixty-three patients who underwent PCI on SVGs from 2017 to 2019 were enrolled. Short-term and long-term cardiac outcomes of patients in the 6-month follow-up, including major adverse cardiac events (MACE) and all causes of death, were collected. The collected data were also analyzed through statistical methods.Results: The mean age of the subjects was 63.26 ± 8.74 years. Out of 63 patients, five patients (7.94%) died. Two of them died because of cardiac death a day after PCI, and three other cases passed away during the 6 months after angioplasty. Four and three cases had non-fatal myocardial infarction and stroke 6 months after PCI, respectively.Conclusion: In conclusion, in patients with coronary artery disease, PCI and CABG are complementary therapies. Revascularization on saphenous vein grafts seems to be a safe and practical technique in patients.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"7-11"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal trend of short-term mortality in acute myocardial between 2000-2017: A multi-centric Iranian registry. 2000-2017年急性心肌短期死亡率的时间趋势：一项多中心伊朗登记

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2023.42291.2929

Mohammad Hossein Paknahad, Zahra Teimouri-Jervekani, Hamidreza Roohafza, Nizal Sarrafzadegan, Fatemeh Nouri, Shima Nasirian, Fatereh Baharlouei Yancheshmeh, Masoumeh Sadeghi

{"title":"Temporal trend of short-term mortality in acute myocardial between 2000-2017: A multi-centric Iranian registry.","authors":"Mohammad Hossein Paknahad, Zahra Teimouri-Jervekani, Hamidreza Roohafza, Nizal Sarrafzadegan, Fatemeh Nouri, Shima Nasirian, Fatereh Baharlouei Yancheshmeh, Masoumeh Sadeghi","doi":"10.48305/arya.2023.42291.2929","DOIUrl":"10.48305/arya.2023.42291.2929","url":null,"abstract":"Background: The study explores the enduring challenges of cardiovascular disease mortality, emphasizing myocardial infarction rates as a proxy for cardiovascular disease in Iran. It analyzes the 28-day mortality trends after Acute Myocardial Infarction (AMI) from 2000 to 2017.Methods: This retrospective cohort study is based on data from a multi-centric hospital-based registry in Isfahan. Univariate and multivariate frailty Cox regression analyses were performed to identify Hazard Ratios (HRs) for the 28-day mortality rate of AMI based on age, gender, and living region.Results: The study enrolled 121,284 patients with an average age of 62.00±12.82 years. Older age than 65 years was found to be associated with an increased risk of AMI (HR: 3.2, 95% CI: 2.7-3.8 from 2000 to 2002 and HR: 4.6, 95% CI: 3.7-5.7 for 2015-2017). There was also an association between living in the urban region and a decreased risk of AMI from 2000 to 2005 (HR: 0.64, 95% CI: 0.46-0.90), from 2000 to 2002 (HR: 0.55, 95% CI: 0.43-0.71 for 2003-2005). Results showed that the trend of change in 28-day mortality declined more significantly from 2006 to 2017 compared to 2000-2002. Younger age (61.76±12.69 vs 71.12±11.73), female gender (HR:0.77, 95%CI: 0.67,0.89), and living in urban regions (HR: 0.69, 95%CI: (0.52,0.94) were the protective factors for the 28-days mortality rate of AMI.Conclusion: It can be concluded that 28-day mortality had a descending trend from 2006 to 2017. Older age, male gender, and living in a rural region were the risk factors that affected the 28-day mortality rate of AMI.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"37-44"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive power of glycated hemoglobin in detecting severity of coronary artery disease in non-diabetic patients: A cross-sectional study in southern Iran. 糖化血红蛋白检测非糖尿病患者冠状动脉疾病严重程度的预测能力：伊朗南部的一项横断面研究

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42463.2936

Shahin Abbaszadeh, Shideh Rafati, Daryoush Mamikhani, Mahdieh Emami, Nahid Shahabi

{"title":"Predictive power of glycated hemoglobin in detecting severity of coronary artery disease in non-diabetic patients: A cross-sectional study in southern Iran.","authors":"Shahin Abbaszadeh, Shideh Rafati, Daryoush Mamikhani, Mahdieh Emami, Nahid Shahabi","doi":"10.48305/arya.2024.42463.2936","DOIUrl":"10.48305/arya.2024.42463.2936","url":null,"abstract":"Background: The relationship between hemoglobin A1c (HbA1c) levels and coronary artery disease (CAD) severity is still a matter of debate in non-diabetic patients. This study aimed to determine the association between HbA1c and the severity of CAD in non-diabetic patients.Methods: The present cross-sectional study was conducted in 2018-2019 on 133 non-diabetic patients with stable angina, unstable angina, or myocardial infarction (MI). They were selected through systematic random sampling. The data were collected by taking a complete medical history, calculating the SYNTAX score, and measuring HbA1c.Results: A SYNTAX score of >22 was significantly correlated with age, left ventricular ejection fraction, HbA1c, and total cholesterol. The mean SYNTAX score was higher in male patients, those with HbA1c >5.6, and patients with a primary clinical presentation of MI. The association between the SYNTAX score and HbA1c was found to be statistically significant (r = 0.659; P < .001). The odds of having a SYNTAX score of >22 for those with HbA1c >5.6 was 5.48 times higher than for those with HbA1c ≤ 5.6 (odds ratio [OR], 5.48; P < .001). The odds of three-vessel disease in individuals with an HbA1c level greater than 5.6 were found to be 4.80 times higher than in those with HbA1c levels at or below 5.6 (OR, 4.80; P = 0.002).Conclusion: The present findings showed that HbA1c has the potential to predict the severity of CAD in non-diabetic individuals. HbA1c, even at levels within the normal range, was significantly correlated with SYNTAX scores.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 5","pages":"15-24"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-procedural necrotizing fasciitis following femoral coronary angiography in patient with chronic endocarditis: A case report. 慢性心内膜炎患者行股冠状动脉造影后坏死性筋膜炎1例。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42517.2944

Hosein Masoumi, Ehsan Shirvani, Fereshteh Sattar

{"title":"Post-procedural necrotizing fasciitis following femoral coronary angiography in patient with chronic endocarditis: A case report.","authors":"Hosein Masoumi, Ehsan Shirvani, Fereshteh Sattar","doi":"10.48305/arya.2024.42517.2944","DOIUrl":"10.48305/arya.2024.42517.2944","url":null,"abstract":"Background: Necrotizing fasciitis is a life-threatening soft tissue infection characterized by rapid tissue necrosis, often leading to sepsis and multisystem organ failure. Necrotizing fasciitis can rarely occur as a post-procedural complication, particularly following cardiac catheterization or angiography. This case report presents the clinical presentation and management of a 64-year-old female with a history of chronic endocarditis and valvular involvement who developed necrotizing fasciitis after femoral coronary angiography.Case presentation: A 64-year-old female with a history of chronic endocarditis and valvular involvement underwent femoral coronary angiography as part of her cardiac evaluation. On the first postoperative day, the patient developed worsening pain, swelling, and redness in her right lower extremity, which worsened despite antibiotic therapy and pain management. The patient was diagnosed with necrotizing fasciitis. An emergent right lower extremity fasciotomy was performed to debride the necrotic tissue and release the tension caused by acute compartment syndrome.Conclusion: This case underscores the importance of maintaining a high index of suspicion for NF in patients with persistent soft tissue infection symptoms post-procedure. Early recognition, prompt diagnosis, and aggressive surgical intervention are crucial for the successful management of post-procedural NF following femoral coronary angiography. This report emphasizes the need for a multidisciplinary approach and vigilance in caring for patients to ensure optimal outcomes in such rare but severe complications.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 5","pages":"1-5"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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