ARYA Atherosclerosis最新文献

{"title":"Predicting the presence and severity of coronary artery disease using surrogate markers of insulin resistance: A cross-sectional study.","authors":"Soodeh Jahangiri, Seyed Arad Mosalamiaghili, Reza Heydarzadeh, Mohammadali Yousefzadeh, Reza Golchin Vafa, Hooyar Zarifkar, Kasra Assadian, Sina Sohrabizadeh, Hourshad Zarifkar, Mehrdad Sadeghi, Nazanin Hosseini, Mohammad Montaseri, Seyed Ali Hosseini, Javad Kojuri","doi":"10.48305/arya.2025.42573.2960","DOIUrl":"10.48305/arya.2025.42573.2960","url":null,"abstract":"<p><strong>Background: </strong>The triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, Metabolic Score for Insulin Resistance (METS-IR), triglyceride-glucose (TyG) index, and triglyceride-glucose body mass index (TyG-BMI) have been associated with the occurrence and severity of coronary artery disease (CAD), although evidence remains limited.</p><p><strong>Methods: </strong>A total of 1,017 patients undergoing coronary angiography for the first time were included. Insulin resistance (IR) indices were calculated based on patients' laboratory data. Significant CAD was defined as more than 50% stenosis observed in coronary angiography¹.</p><p><strong>Results: </strong>A positive correlation was found between CAD and the TyG index (ρ = 0.083, p = 0.008). Patients with CAD had a significantly elevated TyG index (9.02 ± 0.62) compared to those with single-vessel disease (SVD) (8.87 ± 0.59) (p = 0.012). A strong association was observed between CAD and the TG/HDL-C ratio (ρ = 0.114, p < 0.001). Patients with multi-vessel disease exhibited a considerably higher index (4.47 ± 2.46) compared to those with SVD (3.77 ± 2.45) (p = 0.003). The TyG index cut-off was 9.22 (27.5% sensitivity, 79.3% specificity, 82.2% positive predictive value (PPV), and 23.89% negative predictive value (NPV)), while the TG/HDL-C ratio cut-off was 3.6 (44% sensitivity, 65.2% specificity, 81.5% PPV, and 25.5% NPV).</p><p><strong>Conclusion: </strong>Our findings indicate that the TG/HDL-C ratio, with a cut-off point of 3.6, and the TyG index, with a threshold of 9.22, are associated with the presence of CAD. (ClinicalTrials.gov registration number: NCT06237244).</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 1","pages":"44-53"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The study of electrocardiographic changes in 5-15 years old children referred with chest pain to Hajar and Imam Ali hospitals in Shahrekord, Southwestern Iran, in year 2017.","authors":"Nabiolah Asadpour, Mohammad Reza Malekahmadi, Soleiman Kheiri, Mohammad Esmaeili","doi":"10.48305/arya.2024.31309","DOIUrl":"10.48305/arya.2024.31309","url":null,"abstract":"<p><strong>Background: </strong>Chest pain is a common complaint among children referred to treatment centers. This study aimed to investigate the electrocardiographic changes in children aged 5-15 years with chest pain referred to Hajar and Imam Ali Hospitals of Shahrekord.</p><p><strong>Methods: </strong>In this descriptive-analytic study, 350 children with chest pain who were referred to Hajar and Imam Ali Hospitals were included. After clinical examination, electrocardiography was performed. Echocardiography was conducted in cases with electrocardiographic changes, and CPK-MB and troponin I tests were performed if required. Data were analyzed using SPSS-22 software.</p><p><strong>Results: </strong>The children's ages ranged from 5 to 15 years, with a mean of 10.6 ± 2.7 years. Abnormal electrocardiographic findings were observed in 28 (8%) of the 350 children. Findings included left axis deviation (2.6%), ST elevation (2.9%), ST depression (0.3%), shortened PR interval (0.9%), delta wave changes (0.06%), and cardiac hypertrophy (0.9%). Echocardiography was performed in 70 cases (23.33%), of which 28 (40%) were normal and 42 (60%) had abnormal findings. Mild changes were observed in 39 cases (55.7%), moderate changes in 2 cases (2.9%), and elevated pulmonary arterial pressure in 1 case (1.4%). Thirty girls (8.5%) and 12 boys (3.4%) experienced tachycardia, while 1 boy (0.2%) presented with bradycardia. Troponin I tests were conducted on 2 boys, with both results being negative.</p><p><strong>Conclusion: </strong>Given the importance of heart disease, electrocardiography is recommended for all children presenting with chest pain. Electrocardiography may also serve as a valuable tool for screening heart disease in such cases.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 1","pages":"15-21"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early experience of transcatheter aortic valve implantation (TAVI) procedure in Isfahan, Iran.","authors":"Amir Aris, Asieh Mansouri, Houman Dehghan, Faezeh Tabesh, Mohammad Amini, Alireza Khosravi Farsani","doi":"10.48305/arya.2025.43010.2995","DOIUrl":"10.48305/arya.2025.43010.2995","url":null,"abstract":"<p><strong>Background: </strong>Valve replacement is an optional treatment for patients with severe aortic stenosis (AS) and is associated with a better prognosis and improved quality of life. However, surgical valve replacement may result in severe complications, especially in the elderly. Transcatheter aortic valve replacement (TAVR) for treating symptomatic aortic stenosis has expanded exponentially, becoming a therapeutic option for intermediate- and high-risk patients. To thoroughly examine and monitor its practices and improve outcomes, our TAVI center in Isfahan established a detailed registry as the primary center for the TAVI procedure.</p><p><strong>Methods: </strong>This prospective study was conducted among all patients who underwent the TAVR procedure from September 2022 to December 2023 in Isfahan. Baseline characteristics (demographic, clinical, and procedural), 30-day outcomes, and one-year mortality data were collected.</p><p><strong>Results: </strong>A total of 50 patients underwent the TAVI procedure in Isfahan during our registry. Of these, 56% were male, and the mean age was 77.8 ± 6.7 years. The mean calculated STS score was 5.6. Cardiac death occurred in 4 patients (8%), one (2%) experienced a major vascular complication, 5 (10%) required new pacemaker implantation, and acute kidney injury was observed in 14%. Fever/sepsis occurred in 16%, cardiac tamponade in 6%, one patient (2%) had moderate AI, two patients experienced coronary obstructions, and one suffered a major cerebrovascular accident. Additionally, 4 patients (8%) developed atrial fibrillation, 1 (2%) had ventricular tachycardia, and 6 (12%) experienced AV block.</p><p><strong>Conclusion: </strong>We have shown good both 30-days outcome and one year mortality in our registry that could be a proper option in treating severe AS with comorbidities instead of surgical aortic valve replacement.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 2","pages":"18-27"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of abdominal obesity with the incidence of in-stent restenosis and thrombosis.","authors":"","doi":"10.48305/arya.2025.43542.3033","DOIUrl":"10.48305/arya.2025.43542.3033","url":null,"abstract":"<p><strong>Background: </strong>Given the association between obesity and increased risks of cardiovascular diseases, the acceleration of atherosclerosis, and the significance of patient outcomes after percutaneous coronary intervention (PCI), this study aimed to investigate the relationship between abdominal obesity and the incidence of in-stent restenosis (ISR) or stent thrombosis (ST) following PCI.</p><p><strong>Methods: </strong>This cross-sectional study included 5,980 patients who underwent angioplasty at Chamran Specialty Heart Hospital from March 2023 to February 2025. Of this population, 105 patients who developed ISR or ST and returned to the hospital were evaluated. Their demographic and clinical characteristics were recorded, and waist circumference was measured to assess abdominal obesity.</p><p><strong>Results: </strong>The findings revealed that ISR and ST occurred in 66 (86.8%) and 10 (13.2%) cases, respectively, among patients with abdominal obesity, whereas in patients without abdominal obesity, these complications were observed in 25 (86.2%) and 4 (13.8%) cases, respectively (P > 0.050). Additionally, the incidence of ISR or ST was reported to occur over a longer period in patients without abdominal obesity, whereas it was observed within a shorter timeframe after PCI in patients with abdominal obesity (P < 0.05).</p><p><strong>Conclusion: </strong>According to the results of this study, the prevalence of abdominal obesity was higher in patients with complications of ISR or ST after PCI. Also the incidence of ISR or ST occurred in a longer period of time in patients without abdominal obesity after PCI and in a shorter period of time after PCI in patients with abdominal obesity.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 2","pages":"43-50"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic findings of hospitalized children with covid-19: A cross-sectional study in southeast Iran.","authors":"Mohammad Mehdi Bagheri, Reza Sinaei, Fateme Dortaj, Mehran Ilaghi, Shirin Aboutalebi","doi":"10.48305/arya.2025.42750.2975","DOIUrl":"10.48305/arya.2025.42750.2975","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular involvement represents a potentially serious complication associated with novel coronavirus disease 2019 (COVID-19), particularly among pediatric patients. Data regarding echocardiographic findings remain sparse, especially in low- and middle-income countries. The primary objective of this study was to investigate the echocardiographic findings of hospitalized children with COVID-19 in southeast Iran.</p><p><strong>Methods: </strong>This was a cross-sectional study of hospitalized pediatric COVID-19 patients in Kerman, southeast Iran, between March 2020 and March 2022. Clinical records of patients who had undergone transthoracic echocardiograms were evaluated. Demographic and clinical data, as well as echocardiographic findings-including left ventricular (LV) dysfunction, coronary involvement, valvular abnormalities, and pericardial effusion-were noted. Serum inflammatory markers were also assessed.</p><p><strong>Results: </strong>Data from a total of 188 children were analyzed. The mean age (± standard deviation) was 52.7 ± 4.9 months, and 61.4% were male. In terms of disease severity, 36.1% were categorized as moderate, 47.9% as severe, and 16.0% as multisystem inflammatory syndrome in children (MIS-C). Overall, 92.0% had abnormal echocardiographic findings-most commonly pericardial effusion (55.9%), valvular dysfunction (44.1%), coronary artery involvement (36.7%), and LV dysfunction (19.1%). Mitral regurgitation (36.2%) and tricuspid regurgitation (19.7%) were the most common valvular involvements. Moreover, coronary ectasia (19.7%) and dilatation (13.3%) were the prominent coronary abnormalities. LV dysfunction and valvular abnormalities were associated with increased mechanical ventilation, ICU admission, and mortality. Elevated erythrocyte sedimentation rate (ESR) was associated with valvular dysfunction, while higher NT-proBNP was associated with LV dysfunction.</p><p><strong>Conclusion: </strong>Hospitalized children had a high prevalence of echocardiographic abnormalities, with LV and valvular dysfunction correlating with worse prognosis and inflammation. Echocardiography appears valuable for risk stratification in ventilator support and Intensive Care Unit (ICU) admission in pediatric patients; however, further research is needed on long-term cardiac sequelae.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 4","pages":"6-14"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluate gender differences in patients with left main coronary artery disease.","authors":"Mohammad Haji Aghajani, Mohammad Parsa Mahjoob, Abdolreza Babamahmoodi, Roxana Sadeghi, Naser Kachoueian, Reza Hamneshin Behbahani","doi":"10.48305/arya.2024.42805.2979","DOIUrl":"10.48305/arya.2024.42805.2979","url":null,"abstract":"<p><strong>Background: </strong>Left main coronary artery disease (LMCAD) is a potentially life-threatening situation. The medical treatment of LMCAD can lead to critical cardiovascular events. The association between LMCAD and gender has been studied in the medical field.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at Imam Hossein Hospital in Tehran. At the beginning of the project, patient files were collected for 6,250 individuals who presented with heart complaints between 2016 and 2021 and underwent angiography examinations. These files were reviewed, and patients diagnosed with left main coronary artery disease during the angiography were identified.</p><p><strong>Results: </strong>After reviewing 6,250 angiography results from 2016 to 2021, it was found that 274 patients had significant stenosis in the left main coronary artery, resulting in a prevalence of LMCAD of 4.38%. The mean age of the 274 patients with LMCAD was 65.98 ± 10.29 years, and 22.63% of them had premature CAD. Males constituted 75.18% of the group, with 25.18% being smokers. Common comorbidities included hypertension (51.82%), diabetes (42.70%), and chronic kidney disease (13.50%). The gender-based analysis highlighted variations, with women being older on average (P = 0.007), more likely to have premature left main involvement (P = 0.011), and exhibiting lower rates of smoking (P < 0.001) and chronic kidney diseases (P = 0.013) but higher prevalence of hypertension (P < 0.001) and diabetes (P = 0.011) compared to men.</p><p><strong>Conclusion: </strong>Our findings showed that these gender-specific differences are crucial for tailored management strategies in patients with left main coronary artery disease. Further research is needed to optimize outcomes for this high-risk population.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 1","pages":"1-6"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatopathy and acute kidney injury Following Corrective Cardiac Surgery with cardiopulmonary bypass pump in Pediatric with Congenital Heart Defects.","authors":"Forod Salehi Abarghouei, Tayyebeh Chahkandi, Sayeh Shaban, Seyyed Farhad Raeiszadeh Bajestani, Mohammad Hosein Soleimani, Ahmad Amouzeshi, Shiva Salehi","doi":"10.48305/arya.2025.42947.2989","DOIUrl":"10.48305/arya.2025.42947.2989","url":null,"abstract":"<p><strong>Background: </strong>Congenital heart defects (CHDs) are common anomalies in children. Cardiopulmonary bypass (CPB) is widely used in cardiac surgeries, but it is associated with complications. Liver and kidney injuries frequently occur during CPB. This study aimed to evaluate liver and kidney damage in pediatric patients with CHDs undergoing cardiac surgery with CPB.</p><p><strong>Methods: </strong>This retrospective study examined 51 patients with CHDs who underwent cardiac surgery with CPB at Vali-Asr and Razi hospitals in Birjand, Iran. The study period spanned from 2013 to 2019. Patient information was extracted from hospital records and compiled into checklists, which included demographic data, disease severity, liver function tests, cardiac ejection fraction, and serum levels of hematocrit, direct and indirect bilirubin, albumin, total protein, and creatinine.</p><p><strong>Results: </strong>Among the patients, 52.9% were male and 47.1% were female, with a mean age of 37 months. A total of 78.4% had cyanotic CHDs.After surgery, the levels of AST, ALT, and ALKP increased significantly (P < 0.001), while the levels of indirect bilirubin, albumin, and total protein decreased (P < 0.001). The cardiac ejection fraction also improved following surgery (P < 0.001). However, changes in creatinine and direct bilirubin were not significant. Notably, AST levels were markedly higher in deceased patients compared to survivors.</p><p><strong>Conclusion: </strong>This study revealed significant alterations in liver enzyme levels in patients undergoing cardiac surgery using CPB, potentially indicating liver damage during the procedure. Furthermore, elevated postoperative AST levels were associated with a higher risk of mortality.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 2","pages":"10-17"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of TGF-β1 variation in type 1 diabetes and cardiovascular complications.","authors":"Zohreh Jadali","doi":"10.48305/arya.2025.43337.3016","DOIUrl":"10.48305/arya.2025.43337.3016","url":null,"abstract":"","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"21 2","pages":"1-2"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between GJB2 gene (producing Cx26 protein) and the ventricular storm: A case report.","authors":"Mohammad Hossein Nikoo, Mohammad Reza Hatamnejad, Zahra Emkanjoo, Alireza Arjangzadeh, Mehdi Motahari Moadab, Mehdi Bazrafshan, Hamed Bazrafshan Drissi","doi":"10.48305/arya.2023.11842.0","DOIUrl":"10.48305/arya.2023.11842.0","url":null,"abstract":"<p><strong>Background: </strong>A structural heart disease or functional electrical abnormalities can cause an electrical storm.</p><p><strong>Case presentation: </strong>We present a young boy with an electrical storm who had no cardiac risk factors and a positive family history of sudden cardiac death. The stepwise diagnostic approach was ineffective in determining previously known causes as the origin of the electrical storm. However, whole-exome sequencing (with Next Generation Illumina Sequencing) revealed a mutation in the GJB2 (NM_004004:exon2:c.G71A:p.W24X) gene.</p><p><strong>Conclusion: </strong>A mutation in the GJB2 gene, which forms the connexin 26 protein, a crucial component of the myocytes' intercalated disc of gap junction complex between the myocytes, results in an abnormal electrical cell-by-cell conductance, and, eventually, ventricular storm. General anesthesia was used to control the storm, and intracardiac pacing was fruitful in ceasing the subsequent VT storms.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"1-7"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forty-seven years of Iranian cardiovascular disease scientific publication: A bibliometric and altmetric analysis.","authors":"Ali Ouchi, Fezzeh Ebrahimi, Leila Nemati Anaraki, Seyed Abedin Hoseini Ahangari, Nasim Ansari","doi":"10.48305/arya.2024.42080.2918","DOIUrl":"10.48305/arya.2024.42080.2918","url":null,"abstract":"<p><strong>Background: </strong>The present study was conducted to investigate the scientific contributions of Iranians in the field of cardiovascular research, as indexed in the Scopus database, using bibliometric and altmetric methods.</p><p><strong>Methods: </strong>This applied study was conducted with a scientometric approach, utilizing bibliometric and altmetric indicators. The research population consisted of the scientific works of Iranian researchers in the field of cardiovascular diseases, indexed in the Scopus database over a period of 47 years. For bibliometric analysis and the generation of co-citation, co-occurrence, and co-authorship maps, the authors employed VOS Viewer software and the bibliometrix package in the R programming language. In the final stage, articles mentioned on social media were analyzed and evaluated using an altmetric approach.</p><p><strong>Results: </strong>The results indicated that the commencement point for the publication of documents was 1975, and there has been a steep increase in recent years. Moreover, the documents were primarily research articles out of 6853 retrieved documents, and a limited number of documents were single-authored. Other findings also revealed the co-authorship map of authors and the co-occurrence of words, highly cited authors and institutions, and highly frequent keywords, signifying the scientific collaboration of Iranian researchers with the United States and England. Altmetric analysis also demonstrated that 43.41% of documents were shared at least once on social media and had an Altmetric Attention score. Furthermore, the analysis of altmetric indices showed that Mendeley, Twitter, and News had the highest share of document mentions on social media, respectively.</p><p><strong>Conclusion: </strong>The findings of the study can offer valuable information to researchers, managers, and policy makers to become aware of the current state of research in the field of cardiovascular diseases and implement the necessary policies to inform society and enhance public health status.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"17-30"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}