ARYA Atherosclerosis最新文献

{"title":"The association between GJB2 gene (producing Cx26 protein) and the ventricular storm: A case report.","authors":"Mohammad Hossein Nikoo, Mohammad Reza Hatamnejad, Zahra Emkanjoo, Alireza Arjangzadeh, Mehdi Motahari Moadab, Mehdi Bazrafshan, Hamed Bazrafshan Drissi","doi":"10.48305/arya.2023.11842.0","DOIUrl":"10.48305/arya.2023.11842.0","url":null,"abstract":"<p><strong>Background: </strong>A structural heart disease or functional electrical abnormalities can cause an electrical storm.</p><p><strong>Case presentation: </strong>We present a young boy with an electrical storm who had no cardiac risk factors and a positive family history of sudden cardiac death. The stepwise diagnostic approach was ineffective in determining previously known causes as the origin of the electrical storm. However, whole-exome sequencing (with Next Generation Illumina Sequencing) revealed a mutation in the GJB2 (NM_004004:exon2:c.G71A:p.W24X) gene.</p><p><strong>Conclusion: </strong>A mutation in the GJB2 gene, which forms the connexin 26 protein, a crucial component of the myocytes' intercalated disc of gap junction complex between the myocytes, results in an abnormal electrical cell-by-cell conductance, and, eventually, ventricular storm. General anesthesia was used to control the storm, and intracardiac pacing was fruitful in ceasing the subsequent VT storms.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"1-7"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forty-seven years of Iranian cardiovascular disease scientific publication: A bibliometric and altmetric analysis.","authors":"Ali Ouchi, Fezzeh Ebrahimi, Leila Nemati Anaraki, Seyed Abedin Hoseini Ahangari, Nasim Ansari","doi":"10.48305/arya.2024.42080.2918","DOIUrl":"10.48305/arya.2024.42080.2918","url":null,"abstract":"<p><strong>Background: </strong>The present study was conducted to investigate the scientific contributions of Iranians in the field of cardiovascular research, as indexed in the Scopus database, using bibliometric and altmetric methods.</p><p><strong>Methods: </strong>This applied study was conducted with a scientometric approach, utilizing bibliometric and altmetric indicators. The research population consisted of the scientific works of Iranian researchers in the field of cardiovascular diseases, indexed in the Scopus database over a period of 47 years. For bibliometric analysis and the generation of co-citation, co-occurrence, and co-authorship maps, the authors employed VOS Viewer software and the bibliometrix package in the R programming language. In the final stage, articles mentioned on social media were analyzed and evaluated using an altmetric approach.</p><p><strong>Results: </strong>The results indicated that the commencement point for the publication of documents was 1975, and there has been a steep increase in recent years. Moreover, the documents were primarily research articles out of 6853 retrieved documents, and a limited number of documents were single-authored. Other findings also revealed the co-authorship map of authors and the co-occurrence of words, highly cited authors and institutions, and highly frequent keywords, signifying the scientific collaboration of Iranian researchers with the United States and England. Altmetric analysis also demonstrated that 43.41% of documents were shared at least once on social media and had an Altmetric Attention score. Furthermore, the analysis of altmetric indices showed that Mendeley, Twitter, and News had the highest share of document mentions on social media, respectively.</p><p><strong>Conclusion: </strong>The findings of the study can offer valuable information to researchers, managers, and policy makers to become aware of the current state of research in the field of cardiovascular diseases and implement the necessary policies to inform society and enhance public health status.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"17-30"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The assessment of no-reflow phenomenon incidence in early versus delayed percutaneous coronary intervention following a primary fibrinolysis.","authors":"Afshin Amirpour, Mohammad Amin Behjati, Reihaneh Zavar, Ehsan Shirvani, Ehsan Zarepour, Razieh Hassannejad, Masoumeh Sadeghi, Raheleh Janghorbanian Poodeh, Ali Safaei, Shahin Sanaei, Nazanin Mahin Parvar","doi":"10.48305/arya.2024.42104.2921","DOIUrl":"10.48305/arya.2024.42104.2921","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous coronary intervention (PCI) is the gold standard approach to ST-Segment Elevation Myocardial Infarction (STEMI). Fibrinolysis followed by PCI has been recommended. The current study aims to investigate the no-reflow phenomenon incidence in patients undergoing post-thrombolytic therapy PCI.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on 250 patients with STEMI who primarily received fibrinolytic therapy followed by early (3-24 hours) (n=231) or delayed (> 24 hours) (n=19) PCI. They were also subcategorized into four intervals: <6 hours (n=98), 6-12 hours (n=93), 12-24 hours (n=38), and ≥24 hours (n=21). The demographic and medical data of the patients were retrieved. The Thrombolysis in Myocardial Infarction score (TIMI) was assessed at baseline and at the end of PCI. A TIMI score other than 3 was defined as no-reflow.</p><p><strong>Results: </strong>The incidence of the no-reflow phenomenon was not associated with any of the underlying demographic and medical characteristics of the patients (P-value>0.05). Despite the significantly higher rate of improvement in TIMI grading among those undergoing early PCI (P-value=0.04), as well as within less than 6 hours after thrombolytic therapy (P-value=0.031), the rate of the no-reflow phenomenon did not differ between the groups, neither by sorting them as early versus delayed (P-value=0.518) nor by categorizing them into four intervals (P-value=0.367).</p><p><strong>Conclusion: </strong>Based on the findings of the current study, early PCI after fibrinolysis led to significantly improved TIMI flow. However, the incidence of no-reflow did not differ between the groups with early versus delayed post-fibrinolysis PCI.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"31-40"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiomyopathy discovered during pregnancy: Insights from speckle tracking echocardiography in a cohort of pregnant patients.","authors":"Parvin Bahrami, Azam Soleimani, Reihaneh Zavar, Hosein Masoumi, Farzad Adelparvar","doi":"10.48305/arya.2024.42400.2932","DOIUrl":"10.48305/arya.2024.42400.2932","url":null,"abstract":"<p><strong>Background: </strong>Heart failure (HF) is considered the leading cause of cardiac-related morbidity and mortality during pregnancy. Peripartum cardiomyopathy (PPCM) presents diagnostic challenges, often mirroring dilated cardiomyopathy (DCM). The aim of the study is to evaluate echocardiographic features, including global and segmental longitudinal strain values, in pregnant women with a history of newly diagnosed left ventricular systolic dysfunction (LVSD) in the third trimester of pregnancy.</p><p><strong>Methods: </strong>This cross-sectional study, conducted in two referral cardio-obstetric clinics in Isfahan, Iran, enrolled pregnant women with newly diagnosed LV systolic dysfunction in the third trimester of pregnancy. A multidisciplinary pregnancy heart team assessed the patients. Reevaluation of patients and advanced echocardiographic investigation, including speckle tracking echocardiography (STE), were performed at least six months after delivery.</p><p><strong>Results: </strong>The study included 26 pregnant women. Baseline characteristics revealed varying NYHA functional classes and etiologies, including DCM or non-dilated LV cardiomyopathy and PPCM. Undiagnosed DCM with exacerbation during pregnancy or non-dilated LV cardiomyopathy were the most probable causes for LV systolic dysfunction (65.4%). In five cases, peripartum cardiomyopathy was more relevant. The mean global longitudinal strain (GLS) was -16.94% and -13.95% in PPCM and DCM, respectively. Significantly different regional longitudinal strain numbers among different LV segments in PPCM were observed (P=.042), whereas the segmental strain in DCM patients did not differ.</p><p><strong>Conclusion: </strong>When LVSD is discovered late in pregnancy, it is not easy for the authors to differentiate between peripartum cardiomyopathy and other cardiomyopathies. Advanced echocardiographic techniques, particularly GLS analysis, may be valuable in differentiating between these conditions.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"8-16"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of balloon pulmonary valvuloplasty on longitudinal changes in right ventricular strain and strain rate in pediatric pulmonary stenosis.","authors":"Alireza Ahmadi, Mohammad Reza Sabri, Mehdi Ghaderian, Davood Ramezani Nezhad, Bahar Dehghan, Chehreh Mahdavi, Mohsen Sedighi","doi":"10.48305/arya.2023.41893.2906","DOIUrl":"10.48305/arya.2023.41893.2906","url":null,"abstract":"<p><strong>Background: </strong>Balloon Pulmonary Valvuloplasty (BPV) is a procedure for Pulmonary Stenosis (PS) treatment. In this study, right ventricle (RV) performance was determined through 2D-Speckle Tracking Echocardiography (2D-STE).</p><p><strong>Methods: </strong>The study involved 25 diagnosed children with PS undergoing BPV and 25 normal children. They were examined using 2D-STE and Linear Mixed Model (LMM) approach was used to determine changes in Pulmonary Valve Peak Gradient (PVPG), Tricuspid Annular Plane Systolic Excursion (TAPSE), strain and Strain Rate (SR) for RV, and Ejection Fraction for Left Ventricle (LVEF).</p><p><strong>Results: </strong>Notable differences were found between two groups in TAPSE (<i>P=0.001</i>), global strain (<i>P=0.001</i>), apical septal strain (<i>P=0.024</i>), middle septal strain (<i>P=0.001</i>), basal septal strain (<i>P=0.001</i>), apical lateral SR (<i>P=0.001</i>), middle lateral SR (<i>P=0.007</i>), basal lateral SR (<i>P=0.001</i>), and apical septal SR (<i>P=0.001</i>). Post-BPV, there was an increase in LVEF (<i>P=0.001</i>) and TAPSE (<i>P=0.001</i>) but PVPG decreased (<i>P=0.001</i>). Following BPV, an increase was observed in apical lateral strain (<i>P=0.004</i>), middle septal strain (<i>P=0.001</i>), apical septal strain (<i>P=0.003</i>), middle septal strain (<i>P=0.001</i>), basal septal strain (<i>P=0.048</i>), apical septal SR (<i>P=0.025</i>), and middle septal SR (<i>P=0.023</i>). Gender was remarkably correlated with mean changes in basal lateral strain (<i>P=0.019</i>), middle septal strain (<i>P=0.037</i>), and middle septal SR (<i>P=0.020</i>). Age of PS children was related to mean change in basal septal strain (<i>P=0.031</i>) and basal septal SR (<i>P=0.018</i>).</p><p><strong>Conclusion: </strong>Strain and SR in RV improved post-BPV in children with PS. The gender and age of the children revealed remarkable effects on RV strain and SR changes after BPV.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"41-49"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of myocardial infarction in the elderly: A systematic review and meta-analysis.","authors":"Fatemeh Rajati, Mojgan Rajati, Maryam Chegeni, Mohsen Kazeminia","doi":"10.48305/arya.2024.42327.2930","DOIUrl":"10.48305/arya.2024.42327.2930","url":null,"abstract":"<p><strong>Background: </strong>Myocardial Infarction (MI) refers to the destruction and death of cells in the myocardium of the heart. Its prevalence increases with age due to changes in the cardiovascular system. The aim of the present study was to combine, summarize, standardize, resolve inconsistencies in the results of studies, and investigate the impact of potential factors on the prevalence rate of MI in the elderly through a systematic review and meta-analysis.</p><p><strong>Methods: </strong>This systematic review and meta-analysis was conducted from 1987 to March 2022. All relevant published studies were searched in PubMed, Embase, Scopus, Web of Science (WoS) databases, and Google Scholar search engine using related MeSH/Emtree and Free Text words. The heterogeneity among studies was quantified using the I² index.</p><p><strong>Results: </strong>In the initial search, 35453 studies were identified. After eliminating irrelevant studies, finally, 29 articles with a sample size of 3279136 subjects were included in the meta-analysis. After combining the results of the studies included in the meta-analysis, the total prevalence of MI in the elderly was estimated to be 17.6% (95% CI: 12.8 - 23.7%), 16.1% (95% CI: 11.0 - 22.8%) in males, and 12.5% (95% CI: 9.2 - 16.8%) in females. The prevalence of MI increased with the year of publication and the mean age of the elderly (P < 0.001).</p><p><strong>Conclusion: </strong>The results showed that due to the high prevalence of myocardial infarction (MI) in the elderly, it should be addressed within healthcare systems and policy makers should pay more attention to prevention of MI. However, considering the inclusion of heterogeneous studies, the pooled estimation should be interpreted with caution.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"61-73"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardioprotective effects of aerobic training in diabetic rats: Reducing cardiac apoptotic indices and oxidative stress for a healthier heart.","authors":"Mohammad Ali Gharaat, Hamid Reza Choobdari, Mohsen Sheykhlouvand","doi":"10.48305/arya.2024.41976.2911","DOIUrl":"10.48305/arya.2024.41976.2911","url":null,"abstract":"<p><strong>Background: </strong>The present study evaluated the effects of aerobic training with variable intensities on apoptotic indices of cardiac tissue in fatty diabetic rats.</p><p><strong>Methods: </strong>Twenty-four male Wistar rats were randomly divided into non-diabetic (ND, n=8), trained diabetic (TD, n=8), and control diabetic (CD, n=8) groups. Following a high-fat dietary regimen, type 2 diabetes was induced by streptozotocin, with blood glucose levels above 300 mg/dL considered indicative of diabetes. The TD group underwent aerobic exercise five times a week for six weeks. Subsequently, measurements were taken for left ventricular end-diastolic (LVEDV) and end-systolic volumes (LVESV), ejection fraction (EF%), catalase, caspase-9, P53, glucose, insulin, and HOMA-IR.</p><p><strong>Results: </strong>Aerobic training led to a significant decrease in blood glucose levels (P < 0.01), caspase-9 (P < 0.05), HOMA-IR (P < 0.05), and P53 expression (P < 0.001) compared with the CD group. LVEDV and LVESV decreased significantly (P < 0.05 for both), while LVEF increased significantly (P < 0.05). Catalase activation showed an insignificant increase in the TD group pre- to post-training compared to CD.</p><p><strong>Conclusion: </strong>Incremental aerobic exercise training (6 weeks) may exert a cardioprotective effect in diabetic rats by reducing apoptosis and oxidative stress indices, while simultaneously increasing aerobic fitness and reducing body weight.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 2","pages":"50-60"},"PeriodicalIF":0.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D deficiency and atrial fibrillation: A cross sectional single center study.","authors":"Amir Askarinejad, Hooman Bakhshandeh, Mona Heidarali, Sara Adimi, Zahra Ghaemmaghami, Majid Haghjoo","doi":"10.48305/arya.2024.42018.2915","DOIUrl":"10.48305/arya.2024.42018.2915","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) augments the risk of stroke by 4-5 times. Vitamin D is pivotal in numerous metabolic pathways. A handful of studies have explored the correlation between vitamin D deficiency (VDD) and AF outcomes. Hence, the authors sought to assess the relationship between VDD and AF outcomes.</p><p><strong>Methods: </strong>From December 2021 to February 2023, 190 patients with AF were incorporated into the authors' study. Given the seasonal fluctuation of vitamin D levels, these levels were examined from the start of December until the end of March.</p><p><strong>Results: </strong>The final analysis comprised 190 patients (55.8% male) with an average age of 46.22±15.03. Vitamin D deficiency, insufficiency, and sufficiency were noted in 77 (40.5%), 46 (24.2%), and 67 (35.3%) patients, respectively. Fatigue and syncope were significantly more prevalent in the VDD group than in other groups. Three-vessel disease was more frequent in the VDD group (p-value=0.04). Mortality was more prevalent in patients with VDD (6.31%) compared to the VDI (2.10%) and VDS (0.05%) groups (p = 0.03). Successful cardioversion was significantly more prevalent in the VDS group (p = 0.03).</p><p><strong>Conclusion: </strong>A sufficient level of vitamin D was linked with a better response to cardioversion. However, low vitamin D levels are correlated with higher mortality in AF patients.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 1","pages":"31-40"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142009667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of home care on individuals with chronic heart failure: A comprehensive review.","authors":"Faramarz Kalhor, Amir Shahzeydi, Mohsen Taghadosi","doi":"10.48305/arya.2024.42356.2931","DOIUrl":"10.48305/arya.2024.42356.2931","url":null,"abstract":"<p><strong>Background: </strong>Heart failure is a widespread condition linked to elevated mortality rates, readmission incidents, and healthcare expenditures. Home care has emerged as a promising strategy for managing patients with heart failure. This study seeks to comprehensively review the impact of home care on individuals diagnosed with heart failure.</p><p><strong>Methods: </strong>A comprehensive review was conducted by searching for relevant articles in Persian and English using keywords such as 'Nursing,' 'Home care,' 'Home care services,' Health Care Costs,' 'Heart diseases,' and 'Heart failure' across various databases including SID, Magiran, Ovid, Scopus, Web of Science, CINAHL, ProQuest, Embase and Medline. The search was limited to articles published between 2000 and 2023, focusing on those suitable for the study's purpose.</p><p><strong>Results: </strong>A total of 1,260 articles were initially identified. After eliminating duplicate and irrelevant articles, evaluating the availability of full texts, and applying entry and exit criteria, as well as utilizing the CONSORT, STROBE checklist, and JBI Checklist for qualitative assessment of the studies, a total of 13 English articles were deemed suitable for inclusion in the final review. These studies utilized various study designs to investigate the effects of home care on patients with heart failure.</p><p><strong>Conclusion: </strong>The findings of this study suggest that home care has a positive impact on the quality of life, knowledge, and self-care of patients with heart failure. Additionally, it has been shown to reduce healthcare costs, readmission rates, and mortality. Therefore, it is recommended to prioritize home care for patients with chronic heart failure following discharge.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"45-56"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of traditional atherosclerotic risk factors in newly diagnosed colorectal and breast cancer patients.","authors":"Mohammad Rayati, Noushin Mohammadifard, Zamaneh Vafaei, Masood Shekarchizadeh, Samaneh Mostafavi, Reihaneh Zavar, Ali Darakhshandeh, Mehran Sharifi, Farzaneh Ashrafi, Mohammadreza Khosravifarsani, Ali Akhavan, Fariborz Mokarian, Nadia Najafizadeh, Alireza Sadeghi, Maryam Mirpourian, Jamshid Najafian, Nizal Sarrafzadegan","doi":"10.48305/arya.2024.41900.2908","DOIUrl":"10.48305/arya.2024.41900.2908","url":null,"abstract":"<p><p>Due to the shared risk factors between cardiovascular disease (CVD) and certain cancers such as breast cancer (BC) and colorectal cancer (CRC), our study aimed to assess the CVD risk factors among newly diagnosed patients with BC and CRC. The study utilized baseline data from the ongoing Cardiovascular Events in Breast and Colorectal Cancers (CIBC) cohort study conducted in Isfahan since 2019. Only patients who had recently been diagnosed with BC or CRC and had not undergone any treatment were included in the study. Trained interviewers administered questionnaires to collect information on the demographic, socioeconomic, and smoking status of the participants. Additionally, metabolic and physical factors were measured following established guidelines. A total of 542 patients were included in the study, with 394 (72.7%) diagnosed with BC, 147 (27.1%) with CRC, and one patient having both conditions. The average age of BC patients was 49.46±11.15 years, which was younger compared to CRC patients. The majority of patients (90.8%) were nonsmokers, and a significant proportion (91.2%) did not engage in sufficient physical activity. Less than half of the patients exhibited hypertension, while the prevalence of diabetes was comparatively lower. Obesity, particularly abdominal obesity, was more common among BC patients compared to CRC patients. In our population, we observed that patients with CRC had a higher mean age compared to those with BC, and they exhibited a higher prevalence of common metabolic risk factors. On the other hand, obesity was more prevalent among BC patients. In terms of the shared risk factors between CVD and BC, our population experienced menarche within the expected timeframe, and the mean age of menopause was also within the normal range.</p>","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 4","pages":"1-6"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}