Journal of Optometry最新文献

{"title":"Prevalence of dry eye disease in the low vision population at the University of Colorado","authors":"Kaleb Abbott,&nbsp;Kara S. Hanson,&nbsp;James Lally","doi":"10.1016/j.optom.2023.100501","DOIUrl":"10.1016/j.optom.2023.100501","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the prevalence of diagnosed dry eye syndrome, meibomian gland dysfunction, and blepharitis amongst the low vision population.</p></div><div><h3>Methods</h3><p>A retrospective analysis was conducted on patients seen in the University of Colorado Low Vision Rehabilitation Service between the dates of 12/1/2017 and 12/1/2022. 74 ICD-10 codes were used to identify patients as having dry eye syndrome or not having dry eye syndrome. Data was further analyzed to determine the prevalence of blepharitis and meibomian gland dysfunction using 29 blepharitis and 9 meibomian gland dysfunction ICD-10 codes. Data were also analyzed to determine the age and sex of the patients with diagnosed dry eye syndrome.</p></div><div><h3>Results</h3><p>The percentage of patients with a diagnosis of dry eye syndrome by an eyecare provider was 38.02 %. The prevalence of dry eye syndrome by age group was 3.57 % for 0–19 years, 14.35 % for 20–39 years, 29.07 % for 40–59 years, 43.79 % for 60–79 years, and 46.21 % for 80 and above. The prevalence of meibomian gland dysfunction and blepharitis was 11.90 % and 9.1 % respectively. Dry eye syndrome prevalence amongst males was 31.59 % and 42.47 % for females.</p></div><div><h3>Conclusion</h3><p>This study demonstrates that dry eye syndrome in the low vision population is a significant co-morbidity occurring in over a third of patients in the University of Colorado Low Vision Rehabilitation Service. These findings are meaningful as ocular comfort should not be overlooked while managing complex visual needs.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100501"},"PeriodicalIF":2.3,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000493/pdfft?md5=8b489d8ad98bf28ac2ff838b1ab0dd72&pid=1-s2.0-S1888429623000493-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72015697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring visual acuity and spherical refraction with smartphone screens emitting blue light","authors":"Rosa María Salmerón-Campillo ,&nbsp;Félix Tomás Varona-Gómez ,&nbsp;Mari Ogino ,&nbsp;Stephen Hunter ,&nbsp;Vincent Hussey ,&nbsp;Donny W. Suh ,&nbsp;Rujuta Gore ,&nbsp;Mateusz Jaskulski ,&nbsp;Norberto López-Gil","doi":"10.1016/j.optom.2023.100494","DOIUrl":"10.1016/j.optom.2023.100494","url":null,"abstract":"<div><h3>Introduction</h3><p>A periodical self-monitoring of spherical refraction using smartphones may potentially allow a quicker intervention by eye care professionals to reduce myopia progression. Unfortunately, at low levels of myopia, the far point (FP) can be located far away from the eye which can make interactions with the device difficult. To partially remedy this issue, a novel method is proposed and tested wherein the longitudinal chromatic aberration (LCA) of blue light is leveraged to optically bring the FP closer to the eye.</p></div><div><h3>Methods</h3><p>Firstly, LCA was obtained by measuring spherical refraction subjectively using blue pixels in stimuli shown on organic light-emitting diode (OLED) screens and also grey stimuli with matching luminance. Secondly, the visual acuity (VA) measured with a smartphone located at 1.0 m and 1.5 m and displaying blue optotypes was compared with that obtained clinically standard measurements. Finally, the spherical over refraction obtained in blue light with a smartphone was compared with clinical over-refraction with black and white (B&amp;W) optotypes placed at 6 m.</p></div><div><h3>Results</h3><p>Mean LCA of blue OLED smartphone screens was −0.67 ± 0.11 D. No significant differences (<em>p</em> &gt; 0.05) were found between the VA measured with blue optotypes on a smartphone screen and an eye chart. Mean difference between spherical over-refraction measured subjectively by experienced subjects with smartphones and the one obtained clinically was 0.08 ± 0.34 D.</p></div><div><h3>Conclusions</h3><p>Smartphones using blue light can be used as a tool to detect changes in visual acuity and spherical refraction and facilitate monitoring of myopia progression.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 1","pages":"Article 100494"},"PeriodicalIF":2.3,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000420/pdfft?md5=d70ca5c2f5a333e0a5f081b4f16a9f1d&pid=1-s2.0-S1888429623000420-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71522918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silicone oil insulation effects on flash electroretinogram and visual evoked potential in patients with retinal detachment","authors":"Anastasia Papachristou ,&nbsp;Argiri Lambraki ,&nbsp;Trisevgeni Giannakopoulou ,&nbsp;Miltiadis K. Tsilimbaris ,&nbsp;Sotiris Plainis","doi":"10.1016/j.optom.2023.100502","DOIUrl":"10.1016/j.optom.2023.100502","url":null,"abstract":"<div><h3>Background</h3><p>Silicone oil is used as endotamponade following vitreoretinal surgery to maintain the retina reattached when indicated. This study investigates the hypothesis that silicone oil causes insulation effects on the retina by affecting its response to light.</p></div><div><h3>Methods</h3><p>Electrophysiological responses to a flash stimulus were recorded using full-field electroretinography (ERG) and visual evoked potentials (VEP). Recordings were performed in 9 patients who underwent surgery for retinal detachment, before (1–2 days) and after (2–3 weeks) silicone oil removal (SOR) in both the study and the control eye. Flash ERG and VEP recordings were performed according to the ISCEV standard protocol.</p></div><div><h3>Results</h3><p>Statistically significant differences were found in the study eye in the amplitudes of the ERG responses and their corresponding ratios, i.e. the amplitude after SOR over the amplitude before SOR, in all conditions tested. No differences were observed in the control eye. The mean ratio of photopic ERG response was 3.4 ± 2.4 for the study and 1.0 ± 0.3 for the control eye (<em>p</em>&lt;0.001). The mean ratio of ERG flicker response was 3.1 ± 2.4 and 1.0 ± 0.3, respectively (<em>p</em> = 0.003). Scotopic flash ERG ratio was 5.0 ± 4.4 for the study and 1.3 ± 0.6 for the control eye (<em>p</em> = 0.012). No differences were observed for the amplitude and latency of flash VEP response after SOR.</p></div><div><h3>Conclusions</h3><p>Silicone oil causes a reduction in flash ERG responses; no effect was found on flash VEP responses. ERGs in eyes filled with silicone oil should not be considered representative of retinal functionality, in contrast to VEPs, which are not affected by silicone oil presence.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100502"},"PeriodicalIF":2.3,"publicationDate":"2023-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S188842962300050X/pdfft?md5=cc7affeb50929090883f1478b39c323d&pid=1-s2.0-S188842962300050X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author response to ” Comment on: Photosensitivity and filter efficacy in albinism” JOPTOM-D-23-00096","authors":"Joaquim Torner Jordana ,&nbsp;Tanja Hansen ,&nbsp;Line Kessel","doi":"10.1016/j.optom.2023.100503","DOIUrl":"10.1016/j.optom.2023.100503","url":null,"abstract":"","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100503"},"PeriodicalIF":2.3,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000511/pdfft?md5=93f5a889a467ab6d1a9349899ee2a74d&pid=1-s2.0-S1888429623000511-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of the tear film on the intraocular pressure and the corneal biomechanical properties analyzed with the Ocular Response Analyzer","authors":"Filipe Da Silva,&nbsp;João M. M Linhares,&nbsp;Madalena Lira","doi":"10.1016/j.optom.2023.100488","DOIUrl":"10.1016/j.optom.2023.100488","url":null,"abstract":"<div><h3>Purpose</h3><p>As ocular dryness and glaucoma are more prevalent with increasing age, understanding how the tear film affects tonometry is important. The present study aims to understand the impact that changes in the tear film have on intraocular pressure (IOP), corneal hysteresis, and corneal resistance factor measurements.</p></div><div><h3>Methods</h3><p>Cross-sectional research was conducted and 37 patients were assessed. The tear film lipid layer and the non-invasive break-up time (NIBUT) were evaluated using the Tearscope Plus (Keeler, Windsor, UK). Dry eye symptoms were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire. IOP was measured using rebound tonometry and the Ocular Response Analyzer (ORA, Reichert). Corneal biomechanical properties were measured using ORA.</p></div><div><h3>Results</h3><p>It was found that an increase in the IOP measured with the iCare was directly correlated with the subclass that evaluated symptomatology associated with environmental factors (<em>r</em> = 0.414, <em>p</em>&lt;0.05, Spearman). Goldmann-correlated IOP (IOPg) and Corneal-compensated IOP (IOPcc) values were statistically significantly different between the various interferometric patterns (<em>p</em>&lt;0.05). It was also found that an increase in the corneal biomechanical properties measured with ORA was directly correlated with the overall scores obtained when using the OSDI and some of its subclasses.</p></div><div><h3>Conclusions</h3><p>Tear film interferometric patterns were shown to have some impact on the IOP measured using ORA. The IOP measured with iCare seems to be related to the symptomatology obtained from OSDI. Corneal biomechanical properties were related to the OSDI total score and some of its subclasses. An increase in symptomatology was associated with an increase in the measured biomechanical properties of the cornea.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100488"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000365/pdfft?md5=ef5581fd81f59337af4b560ee593186e&pid=1-s2.0-S1888429623000365-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical reading-related oculomotor assessment in visual snow syndrome","authors":"Barry Tannen ,&nbsp;Alina Sample ,&nbsp;Kenneth J. Ciuffreda ,&nbsp;Noah M. Tannen","doi":"10.1016/j.optom.2023.100500","DOIUrl":"10.1016/j.optom.2023.100500","url":null,"abstract":"<div><h3>Purpose</h3><p>Visual snow syndrome (VSS) is a complex neurological condition presenting with an array of sensory, motor, and perceptual dysfunctions and related visual and non-visual symptoms. Recent laboratory studies have found subtle, basic, saccadic-based abnormalities in this population. The objective of the present investigation was to determine if saccadic-related problems could be confirmed and extended using three common clinical reading-related eye movement tests having well-developed protocols and normative databases.</p></div><div><h3>Methods</h3><p>This was a retrospective analysis of 32 patients (ages 16–56 years) diagnosed with VSS in the first author's optometric practice. There was a battery of three reading-related tests: the Visagraph Reading Eye Movement Test, the Developmental Eye Movement (DEM) Test, and the RightEye Dynamic Vision Assessment Test, all performed using their standard documented protocols and large normative databases.</p></div><div><h3>Results</h3><p>A high frequency of oculomotor deficits was found with all three tests. The greatest percentage was revealed with the Visagraph (56%) and the least with the RightEye (23%). A total of 77% of patients failed at least one of the three tests.</p></div><div><h3>Conclusion</h3><p>The present findings confirm and extend earlier investigations revealing a high frequency of saccadic-based oculomotor problems in the VSS population, now including reading-related tasks. This is consistent with the more general oculomotor/motor problems found in these individuals.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100500"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000481/pdfft?md5=f9d4401eaf9b1c832c9194069039234f&pid=1-s2.0-S1888429623000481-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the impact of childhood vision impairment on reading and literacy in education","authors":"Lynne Loh,&nbsp;Mallika Prem-Senthil,&nbsp;Paul A. Constable","doi":"10.1016/j.optom.2023.100495","DOIUrl":"10.1016/j.optom.2023.100495","url":null,"abstract":"<div><h3>Purpose</h3><p>This systematic review evaluates current literature on the impact vision impairment has on reading and literacy levels within education.</p></div><div><h3>Methods</h3><p>Six databases were searched with inclusion criteria of trials or studies involving children who are blind or vision impaired, and impact on academic or school performance – including reading and literacy. 1262 articles were identified, with 61 papers undergoing full screening. Quality appraisal was performed using Critical Appraisal Skills Program (CASP) and seven articles deemed eligible for inclusion.</p></div><div><h3>Results</h3><p>Included articles achieved a quality score of over 70 % using the CASP checklists. Direct comparison of articles was not possible due to methodological differences in assessing reading and literacy levels. All seven studies investigated aspects of reading speed, with additional measures of reading performance, such as reading reserve, comprehension, and reading accuracy.</p></div><div><h3>Discussion</h3><p>Underlying trends highlighted students with a vision impairment do not perform at same level as their normally sighted peers with respect to reading performance - in terms of speed, but not ability. Additionally, early intervention to enhance literacy skills may help improve educational outcomes. Future direction should be aimed at identifying specific obstacles to learning these students face and providing interventions to improve academic outcomes.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100495"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000432/pdfft?md5=0114f1956d63993d9643cb47e7624d1b&pid=1-s2.0-S1888429623000432-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of computer vision syndrome: A systematic review and meta-analysis","authors":"Fabricio Ccami-Bernal ,&nbsp;David R. Soriano-Moreno ,&nbsp;Milton A. Romero-Robles ,&nbsp;Fernanda Barriga-Chambi ,&nbsp;Kimberly G. Tuco ,&nbsp;Sharong D. Castro-Diaz ,&nbsp;Janeth N. Nuñez-Lupaca ,&nbsp;Josmel Pacheco-Mendoza ,&nbsp;Tomas Galvez-Olortegui ,&nbsp;Vicente A. Benites-Zapata","doi":"10.1016/j.optom.2023.100482","DOIUrl":"10.1016/j.optom.2023.100482","url":null,"abstract":"<div><h3>Purpose</h3><p>This review aimed to estimate the prevalence of computer vision syndrome (CVS) in the general population and subgroups.</p></div><div><h3>Methods</h3><p>A search was conducted in the following the databases: PubMed, SCOPUS, EMBASE, and Web of Science until February 13, 2023. We included studies that assessed the prevalence of CVS in any population. The Joanna Briggs Institute's critical appraisal tool was used to evaluate the methodological quality. A meta-analysis of the prevalence of CVS was done using a random-effects model, assessing the sources of heterogeneity using subgroup and meta-regression analyses.</p></div><div><h3>Results</h3><p>A total of 103 cross-sectional studies with 66 577 participants were included. The prevalence of CVS was 69.0% (95% CI: 62.3 to 75.3; I²: 99.7%), ranging from 12.1 to 97.3% across studies. Point prevalence was higher in women than in men (71.4 vs. 61.8%), university students (76.1%), Africa (71.2%), Asia (69.9%), contact lens wearers (73.1% vs. 63.8%) in studies conducted before the COVID-19 pandemic (72.8%), and in those that did not use the CVS-Q questionnaire (75.4%). In meta-regression, using the CVS-Q scale was associated with a lower prevalence of CVS.</p></div><div><h3>Conclusion</h3><p>Seven out of ten people suffer from CVS. Preventive strategies and interventions are needed to decrease the prevalence of this condition which can affect productivity and quality of life. Future studies should standardize a definition of CVS.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 1","pages":"Article 100482"},"PeriodicalIF":2.3,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000304/pdfft?md5=cfb25c8a10182d12e0d87a3443262175&pid=1-s2.0-S1888429623000304-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of active vision therapy compared to conventional patching therapy on visual acuity and stereoacuity in children with amblyopia","authors":"Rinkal Suwal ,&nbsp;Mahesh Kumar Dev ,&nbsp;Bijay Khatri ,&nbsp;Deepak Khadka ,&nbsp;Arjun Shrestha ,&nbsp;Samata Sharma ,&nbsp;Madan Prasad Upadhyay","doi":"10.1016/j.optom.2023.100484","DOIUrl":"10.1016/j.optom.2023.100484","url":null,"abstract":"<div><h3>Purpose</h3><p>To compare improvements in visual acuity (VA) and stereoacuity between active vision therapy (AVT) and conventional patching therapy in children with amblyopia.</p></div><div><h3>Methods</h3><p>This study included 65 children aged 5 to 16 years (mean age±SD, 11.00±3.29 years) with unilateral amblyopia. Among them, 31 children underwent active vision therapy (AVT group), and 34 children underwent conventional patching therapy (patching group). AVT group underwent three sequential phases of AVT: Monocular phase (pursuit, saccades, fixation, visuomotor, eye-hand coordination, and central peripheral activities), biocular phase (diplopia awareness, antisuppression, monocular fixation in a binocular field, accommodative activities, bilateral integration, and fine motor activities) and binocular phase (fusion and stereopsis). Patching group patched their fellow eyes as per guidelines by Pediatric Eye Disease Investigator Group. Best-corrected monocular VA and stereoacuity were measured at baseline and after three months of therapy in both groups.</p></div><div><h3>Results</h3><p>There were significant improvements in the mean acuities in amblyopic eye (AE) in both AVT (0.32±0.11 logMAR, <em>p &lt;</em>0.001) and patching groups (0.27±0.19 logMAR, <em>p ˂</em> 0.001). However, there was no significant difference in mean acuity gains in AE between AVT and patching groups (<em>p</em> = 0.059). Mean gains in stereoacuities (log seconds of arc) were statistically significant in both AVT (0.81±0.34, <em>p &lt;</em> 0.001) and patching groups (0.32±0.34, <em>p &lt;</em> 0.001). The stereoacuity gain in the AVT group was significantly higher compared to patching group (<em>p &lt;</em> 0.001).</p></div><div><h3>Conclusion</h3><p>Active vision therapy had a better impact than conventional patching therapy in terms of improvement of stereoacuity but not in terms of VA when used for treating children with amblyopia.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 1","pages":"Article 100484"},"PeriodicalIF":2.3,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888429623000328/pdfft?md5=af8304ed5719f538aedacb82d830131e&pid=1-s2.0-S1888429623000328-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epithelial and stromal thickness profile and lens decentration in myopic orthokeratology","authors":"J. González-Pérez ,&nbsp;A. Sánchez-García ,&nbsp;M.A. Parafita","doi":"10.1016/j.optom.2023.100485","DOIUrl":"https://doi.org/10.1016/j.optom.2023.100485","url":null,"abstract":"<div><h3>Purpose</h3><p>To study topographic epithelial and total corneal thickness changes in myopic subjects undergoing successful orthokeratology treatment in connection with the objective assessment of contact lens decentration.</p></div><div><h3>Methods</h3><p>A prospective-observational and non-randomized study in 32 Caucasian myopic eyes undergoing Ortho-k for 3 months. Total, epithelial, and stromal thicknesses were studied before and after Ortho-k treatment, using optical coherence tomography with anterior segment application software. Central, paracentral, and mid-peripheral values are taken along 8 semi-meridians.</p></div><div><h3>Results</h3><p>The central average total corneal thickness was 4.72 ± 1.04 μm thinner after Ortho-K. The paracentral corneal thickness showed no significant changes (<em>p</em> = 0.137), while the mid-peripheral corneal thickness was increased by 3.25 ± 1.6 μm associating this increase exclusively to the epithelial plot (<em>p</em>&lt;0.001). When lens centration was assessed, a lens fitting decentration less than 1.0 mm was found for the whole sample, predominantly horizontal-temporal (87.5%) and vertical-inferior (50%) decentring. Corneal topographical analysis revealed a horizontal and vertical epithelial thickness asymmetric change profile with paracentral temporal thinnest values, and mid-peripheral nasal thickest values.</p></div><div><h3>Conclusions</h3><p>The present study found a central corneal thinning induced by Ortho-k lenses in subjects with moderate myopia, only associated with a change in epithelial thickness, as well as mid-peripheral thickening, that seems to be mainly epithelial in origin. The authors also found a tendency of contact lens decentration toward temporal and inferior areas conditioning an asymmetric epithelial redistribution pattern.</p></div>","PeriodicalId":46407,"journal":{"name":"Journal of Optometry","volume":"17 2","pages":"Article 100485"},"PeriodicalIF":2.3,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71735954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}