International Journal of Surgical Oncology最新文献_第6页

Hepatic marker combination provides relevant score to predict severe morbidity after colorectal metastases-related major hepatectomy 肝标志物联合应用可为预测结直肠癌转移相关大肝切除术后的严重发病率提供相关评分

IF 1.5

International Journal of Surgical Oncology Pub Date : 2018-11-26 DOI: 10.31487/j.JSO.2018.01.004

A. Pontallier, C. Laurent, E. Buscail, F. Muscari, J. Adam, L. Chiche, S. Dabernat, V. Vendrely

{"title":"Hepatic marker combination provides relevant score to predict severe morbidity after colorectal metastases-related major hepatectomy","authors":"A. Pontallier, C. Laurent, E. Buscail, F. Muscari, J. Adam, L. Chiche, S. Dabernat, V. Vendrely","doi":"10.31487/j.JSO.2018.01.004","DOIUrl":"https://doi.org/10.31487/j.JSO.2018.01.004","url":null,"abstract":"Background and objectives: After hepatic resection, liver failure is not diagnosed until the postoperative \u0000day-5. The aim was to identify a biomarker predictive of severe morbidity, the day after major hepatectomy. \u0000Methods: This retrospective study included patients undergoing major hepatectomy for colorectal \u0000metastases, plasma hepatic marker concentrations being determined at postoperative day-one. Outcomes \u0000were 30-day severe morbidity (Dindo III to V) and grade C post-hepatectomy liver failure. \u0000Results: A total of 433 patients were included. Thirty-day severe morbidity, 90-day mortality and grade-C \u0000post-hepatectomy liver failure rates were 15.5%, 2.5% and 2.5% respectively. Using cut-offs determined \u0000by receiver operating characteristic curves the association of serum bilirubin ? 2.1 mg/dL (? 2 N) and \u0000aspartate-amino-transferase ? 450 IU/L (? 10 N) was selected for the best biochemical predictors of severe \u0000morbidity (sensitivity 38%, specificity 94%) and post-hepatectomy failure (sensitivity 100%, specificity \u000091%). In multivariate analysis, this score was independently associated with severe morbidity (HR = 5.98, \u000095% IC 2.65-13.89; P < 0.0001) \u0000Conclusions: The association of plasma bilirubin ? 2.1 mg/dL and aspartate-amino-transferase ? 450 IU/L \u0000is identified as a relevant predictor of severe morbidity and post-hepatectomy failure as early as the first \u0000postoperative day after major hepatectomy for colorectal metastases.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"116 1","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85828804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Cervical Cancer: Predictive Relevance of Preoperative 3-Tesla Multiparametric Magnetic Resonance Imaging. 早期宫颈癌:术前3-特斯拉多参数磁共振成像的预测相关性。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2018-08-01 eCollection Date: 2018-01-01 DOI: 10.1155/2018/9120753

Hyun Jin Roh, Kyung Bin Kim, Jong Hwa Lee, Hwa Jung Kim, Yong-Soon Kwon, Sang Hun Lee

{"title":"Early Cervical Cancer: Predictive Relevance of Preoperative 3-Tesla Multiparametric Magnetic Resonance Imaging.","authors":"Hyun Jin Roh, Kyung Bin Kim, Jong Hwa Lee, Hwa Jung Kim, Yong-Soon Kwon, Sang Hun Lee","doi":"10.1155/2018/9120753","DOIUrl":"https://doi.org/10.1155/2018/9120753","url":null,"abstract":"Objective: We assess the predictive significance of preoperative 3-Tesla multiparametric MRI findings.Methods: A total of 260 patients with FIGO IA2-IIA cervical cancer underwent primary surgical treatment between 2007 and 2016. Univariable and multivariable logistic regression analyses were used to assess the incremental prognostic significance.Results: The clinical predictive factors associated with pT2b disease were MRI parametrial invasion (PMI) (adjusted odds ratio (AOR) 3.77, 95% confidence interval(CI) 1.62-8.79; P=0.02) and MRI uterine corpus invasion (UCI) (AOR 9.99, 95% CI 4.11-24.32; P<0.0001). In multivariable analysis, for underdiagnoses, histologically squamous carcinoma versus adenocarcinoma and adenosquamous carcinoma (AOR 2.07, 95% CI 1.06-4.07; P=0.034) and MRI tumor size (AOR 0.76, 95% CI 0.63-0.92; P=0.005) were significant predictors; for overdiagnoses, these results were MRI tumor size (AOR 1.51, 95% CI 1.06-2.16; P=0.023), MRI PMI (AOR 71.73, 95% CI 8.89-611.38; P<0.0001) and MRI UCI (AOR 0.19, 95% CI 0.01-1.01; P=0.051).Conclusion: PMI and UCI on T2-weighted images through preoperative 3T MRI are useful coefficients for accurate prediction of the pT2b stage; however, careful surveillance is required. Therefore, preoperative decision-making for early cervical cancer patients based on MRI diagnosis should be considered carefully, particularly in the presence of factors that are known to increase the likelihood of misdiagnosis.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2018 ","pages":"9120753"},"PeriodicalIF":1.5,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/9120753","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36438440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Adrenal Metastasis of Hepatocellular Carcinoma in Patients following Liver Resection or Liver Transplantation: Experience from a Tertiary Referral Center. 肝切除或肝移植后肝癌患者肾上腺转移:来自三级转诊中心的经验。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2018-07-29 eCollection Date: 2018-01-01 DOI: 10.1155/2018/4195076

Eva M Teegen, Martina T Mogl, Johann Pratschke, Nada Rayes

{"title":"Adrenal Metastasis of Hepatocellular Carcinoma in Patients following Liver Resection or Liver Transplantation: Experience from a Tertiary Referral Center.","authors":"Eva M Teegen, Martina T Mogl, Johann Pratschke, Nada Rayes","doi":"10.1155/2018/4195076","DOIUrl":"https://doi.org/10.1155/2018/4195076","url":null,"abstract":"Introduction: Adrenal metastasis of hepatocellular carcinoma (HCC) is a rare entity and can be treated by resection, local ablative therapy, or systemic therapy. Unfortunately, data about treatment outcome, especially in liver transplant recipients, are rare.Patients and methods: From 2005 to 2015, 990 liver resections and 303 liver transplantations because of HCC were performed at our clinic. We retrospectively analyzed treatment outcome of the patients with metachronous adrenal metastasis of HCC, who received either resection, local ablation, or surveillance only.Results: 10 patients were identified (0.8%). 7 patients received liver transplantation for primary HCC therapy, 3 liver resection, and 1 a local ablative therapy. 8 patients underwent adrenalectomy (one via retroperitoneoscopy), one was treated with local ablation, and one had surveillance only. Seven out of eight patients had no surgical complications and one experienced a pancreatic fistula, treated conservatively. 37.5% of the resected patients had recurrence 1 year after adrenalectomy and 75% after 2 years. The mean survival time after primary diagnosis of HCC was 96.6±22.4 months. After adrenalectomy, the mean survival time was 112.4±25.2 months. The mean time until tumor recurrence was 13.2±3.8 in the total cohort and 15.8±3.8 months in patients after adrenalectomy. The estimated overall survival after adrenalectomy was 77.2±17.4 months.Conclusion: Metachronous adrenal metastasis occured in less than 1% of HCC patients. Adrenalectomy is a safe procedure and leads to acceptable survival rates even after liver transplantion. Therefore, it should be performed whenever the primary tumor is well controlled and the patient is in adequate physical condition.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2018 ","pages":"4195076"},"PeriodicalIF":1.5,"publicationDate":"2018-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/4195076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36435437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Myxoid Liposarcoma: Prognostic Factors and Metastatic Pattern in a Series of 148 Patients Treated at a Single Institution. 肌样脂肪肉瘤：一个机构治疗的 148 例患者的预后因素和转移模式。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2018-05-16 eCollection Date: 2018-01-01 DOI: 10.1155/2018/8928706

Francesco Muratori, Leonardo Bettini, Filippo Frenos, Nicola Mondanelli, Daniela Greto, Lorenzo Livi, Alessandro Franchi, Giuliana Roselli, Maurizio Scorianz, Rodolfo Capanna, Domenico Campanacci

{"title":"Myxoid Liposarcoma: Prognostic Factors and Metastatic Pattern in a Series of 148 Patients Treated at a Single Institution.","authors":"Francesco Muratori, Leonardo Bettini, Filippo Frenos, Nicola Mondanelli, Daniela Greto, Lorenzo Livi, Alessandro Franchi, Giuliana Roselli, Maurizio Scorianz, Rodolfo Capanna, Domenico Campanacci","doi":"10.1155/2018/8928706","DOIUrl":"10.1155/2018/8928706","url":null,"abstract":"Objectives: The authors reported a retrospective study on myxoid liposarcomas (MLs), evaluating factors that may influence overall survival (OS), local recurrence-free survival (LRFS), metastasis-free survival (MFS), and analyzing the metastatic pattern.Methods: 148 MLs were analyzed. The sites of metastases were investigated.Results: Margins (p = 0.002), grading (p = 0,0479), and metastasis (p < 0,0001) were significant risk factors affecting overall survival (OS). Type of presentation (p = 0.0243), grading (p = 0,0055), margin (p = 0.0001), and local recurrence (0.0437) were risk factors on metastasis-free survival (MFS). Authors did not observe statistically significant risk factors for local recurrence-free survival (LRFS) and reported 55% extrapulmonary metastases and 45% pulmonary metastases.Conclusion: Margins, grading, presentation, local recurrence, and metastasis were prognostic factors. Extrapulmonary metastases were more frequent in myxoid liposarcoma.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2018 ","pages":"8928706"},"PeriodicalIF":1.5,"publicationDate":"2018-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36288323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Granulosa Cell Tumor of the Ovary: A Retrospective Study of 31 Cases and a Review of the Literature. 卵巢颗粒细胞瘤31例临床分析及文献复习。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2018-03-29 eCollection Date: 2018-01-01 DOI: 10.1155/2018/4547892

Manel Dridi, Nesrine Chraiet, Rim Batti, Mouna Ayadi, Amina Mokrani, Khedija Meddeb, Yosra Yahiaoui, Henda Raies, Amel Mezlini

{"title":"Granulosa Cell Tumor of the Ovary: A Retrospective Study of 31 Cases and a Review of the Literature.","authors":"Manel Dridi, Nesrine Chraiet, Rim Batti, Mouna Ayadi, Amina Mokrani, Khedija Meddeb, Yosra Yahiaoui, Henda Raies, Amel Mezlini","doi":"10.1155/2018/4547892","DOIUrl":"https://doi.org/10.1155/2018/4547892","url":null,"abstract":"Background: Adult granulosa cell tumors (AGCTs) are the most common sex cord-stromal tumors. Unlike epithelial ovarian tumors, they occur in young women and are usually detected at an early stage. The aim of this study was to report the clinical and pathological characteristics of AGCT patients and to identify the prognostic factors.Methods: All cases of AGCTs, treated at Salah Azaïz Institute between 1995 and 2010, were retrospectively included. Kaplan-Meier's statistical method was used to assess the relapse-free survival and the overall survival.Results: The final cohort included 31 patients with AGCT. The mean age was 53 years (35-73 years). Patients mainly presented with abdominal mass and/or pain (61%, n = 19). Mean tumor size was 20 cm. The majority of patients had a stage I disease (61%, n = 19). Two among 3 patients with stage IV disease had liver metastasis. Mitotic index was low in 45% of cases (n = 14). Surgical treatment was optimal in almost all cases (90%, n = 28). The median follow-up time was 14 years (1-184 months). Ten patients relapsed (32%) with a median RFS of 8.4 years (6.8-9.9 years). Mean overall survival was 13 years (11-15 years). Stage I disease and low-to-intermediate mitotic index were associated with a better prognosis in univariate analysis (resp., p = 0.05 and p = 0.02) but were not independent prognostic factors.Conclusion: GCTs have a long natural history with common late relapses. Hence, long active follow-up is recommended. In Tunisian patients, hepatic metastases were more frequent than occidental series. The prognosis remains good and initial staging at diagnosis is an important prognostic factor.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2018 ","pages":"4547892"},"PeriodicalIF":1.5,"publicationDate":"2018-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/4547892","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36127276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

Radical Gastrectomy: Still the Cornerstone of Curative Treatment for Gastric Cancer in the Perioperative Chemotherapy Era-A Single Institute Experience over a Decade. 胃癌根治术:围手术期化疗时代胃癌根治性治疗的基石——十多年来单院经验

IF 1.5

International Journal of Surgical Oncology Pub Date : 2018-01-14 eCollection Date: 2018-01-01 DOI: 10.1155/2018/9371492

Harsh Kanhere, Raghav Goel, Ben Finlay, Markus Trochsler, Guy Maddern

{"title":"Radical Gastrectomy: Still the Cornerstone of Curative Treatment for Gastric Cancer in the Perioperative Chemotherapy Era-A Single Institute Experience over a Decade.","authors":"Harsh Kanhere, Raghav Goel, Ben Finlay, Markus Trochsler, Guy Maddern","doi":"10.1155/2018/9371492","DOIUrl":"https://doi.org/10.1155/2018/9371492","url":null,"abstract":"Background and objectives: Most gastric cancer patients now undergo perioperative chemotherapy (POCT) based on the MAGIC trial results. POCT consists of neoadjuvant chemotherapy (NACT) as well as postoperative adjuvant chemotherapy. This study assessed the applicability of perioperative chemotherapy and the impact of radical gastrectomy encompassing a detailed lymph-node resection on outcomes of gastric cancer.Methods: Medical and pathology records of all gastric carcinoma resections were reviewed from 2006 onwards. Pathological details, number of lymph-nodes resected, and proportion of involved nodes, reasons for nonadministration of NACT, complications, recurrence, and survival data were analysed.Results: Only twenty-eight (37.8%) out of 74 patients underwent NACT and only nine completed POCT. NACT was declined due to comorbidities/patient refusal n = 24, early stage n = 14, and emergency presentation n = 8. Patients receiving NACT were much younger. Anastomotic leaks, hospital-mortality, lymph-node yield, and proportion of involved lymph-nodes were similar in both groups. Thirty-two patients died due to recurrence with lymph-node involvement heralding higher recurrence risk and much poorer survival (HR 2.66; p = 0.013).Conclusion: More than 60% patients with resectable gastric carcinoma did not undergo NACT. Radical gastrectomy with lymphadenectomy remained the cornerstone of treatment in this period.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2018 ","pages":"9371492"},"PeriodicalIF":1.5,"publicationDate":"2018-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/9371492","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35938788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Pancreatogastrostomy versus Pancreatojejunostomy: An Up-to-Date Meta-Analysis of RCTs. 胰胃吻合术与胰空肠吻合术:一项最新的随机对照试验荟萃分析。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2017-01-01 Epub Date: 2017-07-17 DOI: 10.1155/2017/7526494

Konstantinos Perivoliotis, Eleni Sioka, Athina Tatsioni, Ioannis Stefanidis, Elias Zintzaras, Dimitrios Zacharoulis

{"title":"Pancreatogastrostomy versus Pancreatojejunostomy: An Up-to-Date Meta-Analysis of RCTs.","authors":"Konstantinos Perivoliotis, Eleni Sioka, Athina Tatsioni, Ioannis Stefanidis, Elias Zintzaras, Dimitrios Zacharoulis","doi":"10.1155/2017/7526494","DOIUrl":"https://doi.org/10.1155/2017/7526494","url":null,"abstract":"Background: A meta-analysis was conducted in order to provide an up-to-date comparison of pancreatogastrostomy (PG) and pancreatojejunostomy (PJ), after pancreatoduodenectomy (PD), in terms of clinically significant postoperative pancreatic fistula (POPF) and other postoperative complications.Methods: This meta-analysis was conducted according to the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic literature search in MEDLINE and Cochrane Central Register of Controlled Clinical Trials was performed. Fixed Effects or Random Effects model was used, based on the Cochran Q test.Results: In total, 10 studies (1629 patients) were included. There was no statistical significance between PG and PJ regarding the rate of clinically significant POPF (OR: 0.70, 95%CI: 0.46-1.06). PG was associated with a higher rate of postpancreatoduodenectomy haemorrhage (PPH) (OR: 1.52, 95%CI: 1.08-2.14). There was no difference between the two techniques in terms of clinically significant PPH (OR: 1.35, 95%CI: 0.95-1.93) and clinically significant postoperative delayed gastric emptying (DGE) (OR: 0.98, 95%CI: 0.59-1.63).Discussion: There is no difference between the two anastomotic techniques regarding the rate of clinically significant POPF. Given several limitations, more large scale high quality RCTs are required.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2017 ","pages":"7526494"},"PeriodicalIF":1.5,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/7526494","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35314866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Noninvasive Encapsulated Follicular Variant of Papillary Thyroid Cancer: Clinical Lessons from a Community-Based Endocrine Surgical Practice. 无创包膜滤泡型甲状腺乳头状癌:来自社区内分泌外科实践的临床经验。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2017-01-01 Epub Date: 2017-04-13 DOI: 10.1155/2017/4689465

Allan Golding, Dana Shively, David N Bimston, R Mack Harrell

{"title":"Noninvasive Encapsulated Follicular Variant of Papillary Thyroid Cancer: Clinical Lessons from a Community-Based Endocrine Surgical Practice.","authors":"Allan Golding, Dana Shively, David N Bimston, R Mack Harrell","doi":"10.1155/2017/4689465","DOIUrl":"https://doi.org/10.1155/2017/4689465","url":null,"abstract":"Objective. Retrospective studies have found that noninvasive encapsulated follicular variant of papillary thyroid cancer (EFVPTC) exhibits highly indolent clinical behavior. We studied the clinical features of our patients with noninvasive EFVPTC tumors culled from a community endocrine surgical practice registry over the past four years. Methods. We interrogated the Memorial Center for Integrative Endocrine Surgery (MCIES) Registry for all recorded encapsulated follicular variant of papillary cancer pathologic diagnoses. We identified a subgroup of patients without capsular or vascular invasion and studied their clinical characteristics. Results. Thirty-seven patients met inclusion and exclusion criteria. The typical patient was young and female. Nodules averaged 3.1 cm in greatest dimension by ultrasound evaluation. Thirteen patients were found to have synchronous malignancies elsewhere in the thyroid (35%). At the time of this writing, we have not seen a clinical recurrence in any of our 37 noninvasive EFVPTC patients. Conclusions. Early clinical follow-up data suggests that the majority of noninvasive EFVPTC tumors exhibit indolent behavior, but clinical decision-making with regard to completion thyroidectomy, central lymph node dissection, and adjunctive radioiodine therapy often depends on the amount and type of synchronous thyroid cancer detected elsewhere in the thyroid gland and the central neck.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2017 ","pages":"4689465"},"PeriodicalIF":1.5,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/4689465","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34982393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers. 局部晚期右结肠癌的整体胰十二指肠切除术。

IF 1.5

International Journal of Surgical Oncology Pub Date : 2017-01-01 Epub Date: 2017-07-02 DOI: 10.1155/2017/5179686

Cihan Ağalar, Aras Emre Canda, Tarkan Unek, Selman Sokmen

{"title":"En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers.","authors":"Cihan Ağalar, Aras Emre Canda, Tarkan Unek, Selman Sokmen","doi":"10.1155/2017/5179686","DOIUrl":"https://doi.org/10.1155/2017/5179686","url":null,"abstract":"Locally advanced right colon cancer may invade adjacent tissue and organs. Direct invasion of the duodenum and pancreas necessitates an en bloc resection. Previously, this challenging procedure was associated with high morbidity and mortality; however, today, this procedure can be done more safely in experienced centers. The aim of this study is to report our experience on en bloc right colectomy with pancreaticoduodenectomy for locally advanced right colon cancers. Between 2000 and 2012, 5 patients underwent en bloc multivisceral resection. No major morbidities or perioperative mortalities were observed. Median disease-free survival time was 24.5 months and median overall survival time was 42.1 (range: 4.5-70.4) months in our series. One patient lived 70 months after multivisceral resection and underwent cytoreductive surgery and total pelvic exenteration during the follow-up period. In locally advanced right colon tumors, all adhesions should be considered as malign invasion and separation should not be done. The reasonable option for this patient is to perform en bloc pancreaticoduodenectomy and right colectomy. This procedure may result in long-term survival with acceptable morbidity and mortality rates. Multidisciplinary teamwork and multimodality treatment alternatives may improve the results.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2017 ","pages":"5179686"},"PeriodicalIF":1.5,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/5179686","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35205921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Results from Survey to Assess Current Trends in Surgical Practice in the Management of Women with Early Stage Cervical Cancer within the BGCS Community with an Emphasis on Routine Frozen Section Examination. 以常规冷冻切片检查为重点的BGCS社区早期宫颈癌妇女外科治疗现状调查结果

IF 1.5

International Journal of Surgical Oncology Pub Date : 2017-01-01 Epub Date: 2017-07-17 DOI: 10.1155/2017/2962450

Kumar Gubbala, Alexandros Laios, Thulumuru Kavitha Madhuri, Pubudu Pathiraja, Krishnayan Haldar, Sean Kehoe

{"title":"Results from Survey to Assess Current Trends in Surgical Practice in the Management of Women with Early Stage Cervical Cancer within the BGCS Community with an Emphasis on Routine Frozen Section Examination.","authors":"Kumar Gubbala, Alexandros Laios, Thulumuru Kavitha Madhuri, Pubudu Pathiraja, Krishnayan Haldar, Sean Kehoe","doi":"10.1155/2017/2962450","DOIUrl":"https://doi.org/10.1155/2017/2962450","url":null,"abstract":"In the UK, more than 3,200 new cases of cervical cancer are diagnosed each year. Early stage cervical cancer (IA2-IB1) treatment comprises central surgery mainly in the form of radical hysterectomy or fertility sparing surgery including trachelectomy as well as systematic pelvic lymphadenectomy to detect metastases and adjust treatment accordingly. Given the variation in determining the lymph node (LN) status, a major prognosticator, we reviewed the current UK practice of LN assessment in women undergoing surgery for early cervical cancer. A 7-question, web-based survey, screened by the BGCS committee, was circulated amongst BGCS members. The overall response rate was 51%. Only 12.5% of the respondents routinely performed frozen section examination (FSE); the main reasons for not doing FSE were the pressure on theatre time (54.5%) and the lack of available facilities (48.5%). When positive pelvic nodal disease was detected, in 21 out of 50 (42%) the planned radical hysterectomy (RH) was aborted. More than 70% of the respondents routinely performed RH without any prior resort to pelvic lymphadenectomy. Pretreatment surgical para-aortic LN assessment was performed by 20% of the respondents. The survey confirms the diversity of the UK practice patterns in the surgical treatment of early cervical cancer.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2017 ","pages":"2962450"},"PeriodicalIF":1.5,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/2962450","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35314865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4