En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers.

IF 1.6 Q4 ONCOLOGY
International Journal of Surgical Oncology Pub Date : 2017-01-01 Epub Date: 2017-07-02 DOI:10.1155/2017/5179686
Cihan Ağalar, Aras Emre Canda, Tarkan Unek, Selman Sokmen
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引用次数: 13

Abstract

Locally advanced right colon cancer may invade adjacent tissue and organs. Direct invasion of the duodenum and pancreas necessitates an en bloc resection. Previously, this challenging procedure was associated with high morbidity and mortality; however, today, this procedure can be done more safely in experienced centers. The aim of this study is to report our experience on en bloc right colectomy with pancreaticoduodenectomy for locally advanced right colon cancers. Between 2000 and 2012, 5 patients underwent en bloc multivisceral resection. No major morbidities or perioperative mortalities were observed. Median disease-free survival time was 24.5 months and median overall survival time was 42.1 (range: 4.5-70.4) months in our series. One patient lived 70 months after multivisceral resection and underwent cytoreductive surgery and total pelvic exenteration during the follow-up period. In locally advanced right colon tumors, all adhesions should be considered as malign invasion and separation should not be done. The reasonable option for this patient is to perform en bloc pancreaticoduodenectomy and right colectomy. This procedure may result in long-term survival with acceptable morbidity and mortality rates. Multidisciplinary teamwork and multimodality treatment alternatives may improve the results.

局部晚期右结肠癌的整体胰十二指肠切除术。
局部晚期右结肠癌可侵犯邻近组织和器官。直接侵犯十二指肠和胰腺需要进行整体切除。以前,这种具有挑战性的手术与高发病率和死亡率有关;然而,今天,这个过程可以在有经验的中心更安全地完成。本研究的目的是报告我们对局部晚期右结肠癌进行整体右结肠切除联合胰十二指肠切除术的经验。2000年至2012年间,5例患者接受了整体多脏器切除术。未观察到主要发病率或围手术期死亡率。在我们的研究中,中位无病生存时间为24.5个月,中位总生存时间为42.1个月(范围:4.5-70.4)。1例患者在多脏器切除后存活了70个月,并在随访期间接受了细胞减少手术和全盆腔切除术。局部进展的右结肠肿瘤,所有粘连应考虑为恶性侵犯,不应进行分离。该患者的合理选择是进行整体胰十二指肠切除术和右结肠切除术。该手术可导致长期生存,发病率和死亡率可接受。多学科的团队合作和多模式的治疗方案可以改善结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
5
审稿时长
20 weeks
期刊介绍: International Journal of Surgical Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of surgical oncology.
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