Indian Journal of Nuclear Medicine最新文献

{"title":"Atypical Appearance on Radioiodine Scintigraphy Due to Achalasia Cardia - A Potential Diagnostic Pitfall.","authors":"Kunal Ramesh Chandekar, Nishikant Avinash Damle, Chandrasekhar Bal","doi":"10.4103/ijnm.ijnm_87_24","DOIUrl":"10.4103/ijnm.ijnm_87_24","url":null,"abstract":"<p><p>We present the case of a 36-year-old woman with papillary thyroid cancer (PTC) who had undergone thyroidectomy and nodal dissection. In addition to thyroid remnant and nodal metastases, initial postoperative radioiodine (RAI) diagnostic whole-body scintigraphy showed abnormal diffusely increased linear band-like uptake in the thorax corresponding to the esophageal contour, raising suspicion of lower esophageal obstruction. Retrospective inquiry revealed a history of long-standing, progressive dysphagia. Findings of computed tomography, barium swallow study, and esophageal manometry were consistent with achalasia cardia. She underwent high-dose RAI therapy for PTC and laparoscopic cardio-myotomy for achalasia cardia. This case report aims to familiarize nuclear medicine physicians with the appearance of achalasia cardia on RAI scintigraphy, which may mask surrounding lymph nodal or vertebral metastases. Such a finding when encountered should also prompt further work-up and appropriate management.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"406-408"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FDG PET Scan in Cutaneous Rosai-Dorfman-Destombes Disease.","authors":"Shrikant Vasantrao Solav, Chakor Vora, Rajlaxmi Jagtap, Shailendra Savale, Ishtiyaq Shaikh, Aman Solav","doi":"10.4103/ijnm.ijnm_121_24","DOIUrl":"10.4103/ijnm.ijnm_121_24","url":null,"abstract":"<p><p>Rosai-Dorfman-Destombes (RDD) disease is also called as sinus histiocytosis and is characterized by enlarged lymph nodes and previously called as non-Langerhans cell histiocytosis. Based on pathologic, molecular, and genetic features, RDD disease has been classified into sporadic noncutaneous (classical nodal, extranodal, neoplasia associated, and autoimmune associated), familial (H syndrome, autoimmune lymphoproliferative syndrome related, and familial NOS), and cutaneous subtypes. Cutaneous RDD disease is not associated with lymphadenopathy or visceral organ involvement. The disease is usually localized and has relatively better long-term prognosis. Presented here is a case of indurated plaque-like skin lesions over the abdomen. ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography scan revealed FDG avid cutaneous-subcutaneous soft-tissue lesions. Histology confirmed the diagnosis of cutaneous RDD disease.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"396-398"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Report on the \"Brics International Forum on Nuclear Medicine\" June 19-21, 2024, Saint Petersburg, Russia.","authors":"Maroor Raghavan Ambikalmajan Pillai, Prabhu Ethiraj","doi":"10.4103/ijnm.ijnm_100_24","DOIUrl":"10.4103/ijnm.ijnm_100_24","url":null,"abstract":"","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"418-420"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Usefulness of FDG PET-CT in the Routine Staging of Gastric Cancer: A Retrospective Analysis from the Lead Cancer Center, Pakistan.","authors":"Jamshed Ali, Sara Baloch, Iftikhar Qayum, Amer Rehman Farooqui, Kashif Sajjad, Zubair Shabbir Khanzada","doi":"10.4103/ijnm.ijnm_69_24","DOIUrl":"10.4103/ijnm.ijnm_69_24","url":null,"abstract":"<p><strong>Background: </strong>Accurate staging of tumors is paramount in the management of cancer patients. Current noninvasive modalities like computed tomography (CT) and fluorodeoxyglucose positron emission tomography (FDG PET) scan offer viable approaches to stage the disease; however, the role of FDG PET-CT in gastric cancer remains unclear, in comparison to esophageal and gastroesophageal junction cancers, where they have proven usefulness.</p><p><strong>Aim: </strong>The primary outcome was to assess the usefulness of FDG PET-CT in staging gastric cancer in our population. The secondary outcome was to compare the positive yield of PET-CT with staging laparoscopy and avidity of FDG PET-CT scan in gastric cancer.</p><p><strong>Materials and methods: </strong>In our institution, FDG PET-CT is routinely used in staging gastric cancer, where CT scan does not show metastases. We did a retrospective analysis of data of gastric cancer patients, who were not known to have metastatic disease, who underwent pretreatment staging workup at our institute between January 2018 and December 2022. Tumor and lymph node (LN) avidity and their association with Lauren classification was assessed. Multivariate regression analysis for factors associated with metastases on FDG PET-CT scan with tumor size, nodal status, and node avidity was also assessed. Data were analyzed using SPSS version 26 for descriptive and comparative statistics; multivariate regression analysis was performed to identify factors affecting the diagnosis of metastases on PET-CT. <i>P</i> =0.05 was considered statistically significant.</p><p><strong>Results: </strong>Tumor avidity was shown in 181 (89.16%) patients, and LN avidity in 80 (39.4%) patients. This was independent of the Lauren classification. In addition, previously unidentified metastases were highlighted in 16 (8%) patients. Multivariate regression analysis for factors associated with metastases on FDG PET-CT scan showed a significant association with tumor size (<i>P</i> < 0.001), nodal status (<i>P</i> = 0.005), and node avidity (<i>P</i> = 0.024).</p><p><strong>Conclusions: </strong>FDG PET-CT scan can identify an additional 8% of previously unidentified metastases, thereby playing a useful role in the staging workup of advanced gastric cancer patients. Approximately 90% of gastric cancers and 40% of LNs were PET avid in our population.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"347-352"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[18F]FDG- PET/CT Imaging Spectrum of the Most Prevalent Adrenal Lesions.","authors":"Man Mohan Singh, Pravin Suresh Pareek, Lavish Kakkar, Priyamedha Bose Thakur, Satyawati Deswal","doi":"10.4103/ijnm.ijnm_63_24","DOIUrl":"10.4103/ijnm.ijnm_63_24","url":null,"abstract":"<p><p>Detection of adrenal lesions either incidentally, or in symptomatic cases and/or during staging/restaging of oncological cases, it is very crucial to know the adrenal lesion is benign or malignant. Fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) helps in this comprehensive evaluating process. Here, we present the most frequently facing adrenal lesions in routine oncological PET/CT scans. The aim of this presentation is to know the FDG uptake spectrum of various adrenal lesions on PET/CT scan so that increase the diagnostic accuracy and spectrum of differential diagnosis.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"370-375"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Atlas of Gallium-68-fibroblast Activation Protein Inhibitor (FAPI) in Oncology and Nononcology Imaging.","authors":"Shrikant Vasantrao Solav, Rajlaxmi Rangrao Jagtap, Shailendra V Savale","doi":"10.4103/ijnm.ijnm_70_24","DOIUrl":"10.4103/ijnm.ijnm_70_24","url":null,"abstract":"<p><p>Fibroblast activation protein (FAP) is a quinoline-based membrane bound glycoprotein enzyme. It is not expressed in normal adult tissue except for the myometrium and sometimes in pancreas. The expression increases in inflammation and in cancer-associated fibroblasts. Gallium 68-FAP inhibitor (FAPI) is known to localize in various neoplasms by the virtue of their property of cancer-associated fibroblast activity. Fibroblasts are also known to be associated in inflammatory and infectious condition such as cholecystitis, pyelonephritis, and tuberculosis. Immunoglobulin G4 related disease (IgG4RD) is characterized by infiltration of various tissues with IgG4-rich lymphoplasmacytic fibrotic tissue and has been reported to express cancer-associated fibroblast. The time-tested molecule for cancer imaging F18-fluorode-oxyglucose requires 4-6 h of fasting state. Ga68-FAPI does not require fasting. This pictorial essay illustrates various entities, cancerous as well as noncancerous using Ga68-FAPI positron emission tomography computed tomography (PET CT) imaging.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"360-369"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Cross-sectional and Correlative Imaging in Differentiated Thyroid Carcinoma with Unusual Presentation of Adrenal Metastases - Case Series and Review of Literature.","authors":"Piyush Aggarwal, Venkata Subramanian Krishnaraju, Ashwani Sood, Yamini Mathur, Anish Bhattacharya, Bhagwant Rai Mittal","doi":"10.4103/ijnm.ijnm_76_24","DOIUrl":"10.4103/ijnm.ijnm_76_24","url":null,"abstract":"<p><p>Differentiated thyroid carcinoma (DTC) metastasizing to the adrenal glands is very infrequent. We present three cases of DTC with adrenal metastasis in their follow-up, in which two were from follicular thyroid carcinoma and one from papillary thyroid carcinoma along with review of literature to emphasize the role of cross-sectional and correlative imaging in DTC with adrenal metastasis.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"399-405"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> Study to Compare Stability and Homogeneity of Various Routinely Used Meals for Gastric Emptying Scintigraphy (GES) for Solids and Validating Radiolabeled Idli (Savory Cake) as an Improved Alternate Vegetarian Meal.","authors":"Prathamesh Rajai, Natasha Singh, Divya Shivdasani, Melwika Pereira","doi":"10.4103/ijnm.ijnm_132_23","DOIUrl":"10.4103/ijnm.ijnm_132_23","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to compare the stability and homogeneity of various routinely used meals for gastric emptying scintigraphy (GES) for solids and to validate an improved vegetarian well uniformly radiolabeled solid meal for GES, which is easily fully consumed by patients in view of their common symptoms in such indications and in keeping with Indian food culture.</p><p><strong>Materials and methods: </strong>Following various types of solid meal preparations were labeled with 3 mCi of 99 mTc sulfur colloid (SC), and image of each meal was acquired on General Electric (GE) Infinia Hawkeye 4 camera: (1) Meal of 4 slice bread + 20 g butter with calorific value ≈ 356 kcal. (2) 4 slice bread + 30 g jam with calorific value ≈ 332 kcal. (3) 4 slice bread + 70 ml of milk with calorific value ≈ 243 kcal. (4) 150 g of sagu (sabudana) +5 ml refined vegetable oil + 10 g peanuts (sagu khichdi) with calorific value ≈ 324 kcal. (5) 4 idli + 2 tablespoon green chutney with calorific value ≈ 280 kcal. (6) 70 g wheat + 50 ml water + 5 ml refined vegetable oil with calorific value ≈ 237 kcal. (7) Meal of 75 g of idli mix + 80 ml water + 10 g butter with calorific value ≈ 310 kcal. All radiolabeled meals were subjected to the radiolabeled stability test procedure to calculate labeling efficiency which was compared.</p><p><strong>Results: </strong>Idli meal prepared with radiotracer added to the batter mixture itself, with a calorific value ≈ 310 kcal showed the highest uniform Tc99 m SC distribution in comparison to all other meal preparations.</p><p><strong>Conclusions: </strong>Radiolabeled idli (savory cake) prepared with radiotracer added to the batter mixture itself, appears to be an ideal vegetarian meal in comparison to all other meal preparations for gastric emptying scintigraphy studies, especially among patients with specific dietary restrictions.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"335-340"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Autonomously Functioning Thyroid Nodule: An Unusual Imaging Finding.","authors":"Tejasvini Singhal, Kanhaiyalal Agrawal, Tara Prasad Tripathy, Girish Kumar Parida","doi":"10.4103/ijnm.ijnm_40_24","DOIUrl":"10.4103/ijnm.ijnm_40_24","url":null,"abstract":"<p><p>A 48-year-old female, a known case of ulcerative colitis, on routine workup, was incidentally detected to have biochemical hyperthyroidism. ^99mTc pertechnetate thyroid scintigraphy performed for the evaluation of hyperthyroidism revealed two foci of increased tracer uptake in the right thyroid lobe with suppressed uptake in the rest of the thyroid gland consistent with dual autonomously functioning thyroid nodules.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"393-395"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[18F]FDG- PET/CT in Staging and Restaging of Fetal Type Adenocarcinoma of the Lung: A Case Report and a Review of the Literature.","authors":"Pietro Bellini, Francesco Dondi, Gian Luca Viganò, Francesco Bertagna","doi":"10.4103/ijnm.ijnm_113_24","DOIUrl":"10.4103/ijnm.ijnm_113_24","url":null,"abstract":"<p><p>Fetal type adenocarcinoma (FTA) is a rare malignant tumor of the lung that histologically resembles an embryonic lung. Due to its rarity, no studies had investigated the possible role of the ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) in the initial assessment and/or in the restaging of the disease yet. We present a case of a male patient with tongue carcinoma and incidental findings of well-differentiated FTA at [¹⁸F]FDG PET/CT. The patient was treated by specific therapy and also performed a subsequent [¹⁸F]FDG PET/CT scan that showed a significant reduction of the uptake on lung lesion. This case highlights the potential role and usefulness of PET imaging for staging and posttherapeutic restaging of well-differentiated FTA. The review of the available literature underlined the rarity of the disease since only seven reports were present. Anyway, a possible role of the [¹⁸F]FDG PET/CT in the staging of FTA is conceivable.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"39 5","pages":"376-380"},"PeriodicalIF":0.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}