Journal of Audiology and Otology最新文献

{"title":"Ear Symptoms and Earphone Usage: A Web-Based Survey Study.","authors":"Ga-Young Kim, Mini Jo, Young Sang Cho, Il Joon Moon","doi":"10.7874/jao.2024.00192","DOIUrl":"https://doi.org/10.7874/jao.2024.00192","url":null,"abstract":"<p><strong>Background and objectives: </strong>: This study aimed to investigate the potential impact of earphone use on the occurrence of otitis externa (OE) by conducting a survey.</p><p><strong>Subjects and methods: </strong>: This study included 517 participants. The questionnaire comprised 22 items divided into three categories; general information, earphone use, and OE. The questionnaire was designed using Google Forms and distributed through a notice posted on a hospital bulletin board. This notice included a QR code that enabled any interested individual to participate, and the responses were collected automatically.</p><p><strong>Results: </strong>: The proportion of respondents who had experienced OE at least once was 21%. Among them, 33.7% experienced OE within the preceding month. For \"adhering to the recommendation usage time,\" individuals who responded \"likely\" had a 0.440 (odds ratio=0.440, 95% confidence interval=0.195-0.993) times higher likelihood; they were at lower risk of experiencing OE compared to those who responded \"very unlikely.\"</p><p><strong>Conclusions: </strong>: Our findings suggest that proper earphone use can reduce the risk of OE. Despite the lack of a significant relationship between earphone type, physical activity, and cleaning practices, continued adherence to these factors is recommended to prevent OE.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Study of the Time of Onset of Hearing Loss in Bus Drivers Following Exposure to Occupational Noise.","authors":"H M Apoorva, Jayaram Mannarukrishnaiah","doi":"10.7874/jao.2024.00626","DOIUrl":"https://doi.org/10.7874/jao.2024.00626","url":null,"abstract":"<p><strong>Background and objectives: </strong>: Occupational noise exposure is a significant risk factor for hearing loss, affecting approximately 5% of the global population. Although noise-induced hearing loss is commonly associated with reduced sensitivity to pure tones, there is limited information regarding when this hearing loss begins after noise exposure. This study aimed to investigate the time of onset of hearing loss in bus drivers exposed to noise for varying durations.</p><p><strong>Subjects and methods: </strong>: The study involved 102 bus drivers aged 25-40 years who had been exposed to noise for periods ranging from 6 months to over 10 years. A control group comprising 102 age-matched individuals without noise exposure was also included. Pure-tone audiometry was performed to assess hearing loss, and time of onset of hearing loss relative to noise exposure duration was evaluated.</p><p><strong>Results: </strong>: Bus drivers experienced only \"slight\" hearing loss, even after 10 years of noise exposure. By contrast, reduced sensitivity to pure tones was observed after 25 to 48 months of exposure.</p><p><strong>Conclusions: </strong>: This study confirms that prolonged noise exposure leads to \"slight\" hearing loss, which can appear as early as 25-48 months after exposure to noise. Among individuals under 40 years of age, significant hearing loss appeared to occur only after 10 or more years of exposure. These findings suggest that the impact of noise on hearing acuity may have been overestimated in previous studies.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Amplitudes of Binaural Interaction Components Elicited by Diverse Stimuli and Their Relationships With Behavioral Measures in Individuals With Normal Hearing.","authors":"Won So, Sungmin Lee","doi":"10.7874/jao.2024.00612","DOIUrl":"https://doi.org/10.7874/jao.2024.00612","url":null,"abstract":"<p><strong>Background and objectives: </strong>: This study was performed to comprehensively examine the amplitudes of the binaural interaction components (BICs) elicited by chirps, clicks, and 500 Hz tone-burst stimuli in individuals with normal hearing. Electrophysiological evidence of BICs was obtained and assessed for correlations with interaural time difference (ITD) and interaural level difference (ILD).</p><p><strong>Subjects and methods: </strong>: Sixteen adults (4 males and 12 females) with normal hearing participated in this study. Auditory brainstem responses (ABRs) to chirp, click, and 500 Hz tone-burst stimuli were recorded, and BICs were derived based on wave V. The behavioral thresholds of ITDs and ILDs across multiple frequencies were obtained and analyzed.</p><p><strong>Results: </strong>: BICs were found in most participants, regardless of stimulus type. The amplitudes of BICs elicited by chirps were the highest, followed by those elicited by clicks and 500 Hz tone-bursts. A significant correlation was found between the amplitudes of chirp-evoked BICs and the thresholds of 500 Hz ITDs and ILDs.</p><p><strong>Conclusions: </strong>:This study found that chirp stimuli may be effective in eliciting BIC and predicting behavioral binaural interaction processing at low frequencies.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Understanding the Molecular Dynamics of Autosomal Dominant Auditory Neuropathy: Unveiling a Novel DIAPH3 Gene Variant Associated With Sensorineural Hearing Loss and Bilateral Vestibular Aqueduct Enlargement.","authors":"Gianmaria Miolo, Francesco Margiotta, Alessandra Murgia, Lara Della Puppa, Giuseppe Corona","doi":"10.7874/jao.2024.00143","DOIUrl":"https://doi.org/10.7874/jao.2024.00143","url":null,"abstract":"<p><p>Auditory neuropathy is characterized by abnormal neural conduction in the auditory pathway despite normal outer hair cell function, exhibiting substantial genetic heterogeneity and phenotypic variability. We report the case of a 29-year-old male patient with hearing loss, bilateral enlargement of the vestibular aqueduct (EVA), and vestibular system dysfunction. Based on these features, which are tipically indicative of Pendred syndrome, a molecular investigation including the SLC26A4 gene was performed. This analysis identified a novel heterozygous missense variant, c.411A>C, in exon 4 of the DIAPH3 gene, likely associated with autosomal dominant auditory neuropathy. This point mutation results in substituting glutamic acid with aspartic acid at position 137 p.(Glu137Asp), in the functional Rho-GTPase-binding domain of the DIAPH3 protein. Segregation analysis of the parents and two siblings of the proband revealed the variant's de novo origin. According to the American College of Medical Genetics and Genomics criteria, this finding underscores the need to reclassify the variant as likely pathogenic. This is the first evidence of an association between a DIAPH3 variant and hearing loss coupled with bilateral EVA and vestibular system dysfunction. This finding contributes to a better understanding of the phenotypic complexity of disorders grouped within the auditory neuropathy spectrum.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Near-Infrared Spectroscopy Analysis of the Cognitive Functions of Elderly Patients With Hearing Loss.","authors":"Seung Jae Lee, Jiwon Choi, Hyun Bok Song, Jeong-Sug Kyong, Sang-Yeon Lee, Jun Ho Lee","doi":"10.7874/jao.2024.00318","DOIUrl":"10.7874/jao.2024.00318","url":null,"abstract":"<p><strong>Background and objectives: </strong>Age-related hearing loss is a modifiable risk factor for mild cognitive impairment (MCI); however, the potential mechanisms linking these conditions remain unclear. Therefore, in this study, we analyzed the cognitive function profiles of elderly patients with hearing loss via functional near-infrared spectroscopy (fNIRS) to determine the cortical activity differences between patients at risk of MCI and those with normal cognition. Materials and.</p><p><strong>Methods: </strong>Sixty-three elderly patients with bilateral, moderate, or severe hearing loss were prospectively recruited for this study. Their demographic information was obtained, and audiological evaluations and cognitive function tests were performed. Various instruments were used to assess the cognitive and depression domains. Additionally, fNIRS was used to image the brains of the normal group and group at risk of MCI.</p><p><strong>Results: </strong>fNIRS analysis of individual cognitive task data revealed that the normal group exhibited significantly higher oxygenated hemoglobin (HbO2) levels in all cognitive function tasks, except the Stroop color and word test, than the group at risk of MCI. Detailed comparisons of the Brodmann areas revealed that, compared to the group at risk of MCI, normal group exhibited significantly higher HbO2 levels in the right and left dorsolateral prefrontal cortices, ventrolateral prefrontal cortex, frontopolar cortex, and orbitofrontal cortex in the J1 task, right ventrolateral prefrontal cortex in the J2 task, and right orbitofrontal cortex in the J6 task.</p><p><strong>Conclusions: </strong>Measurement of fNIRS signals in the frontal lobes revealed different HbO2 signals between the normal group and group at risk of MCI during minimal hearing loss. Future studies should explore the causal link between hearing loss and cognitive impairment by analyzing the changes in cognitive function after auditory rehabilitation.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"29 1","pages":"38-48"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Exploratory Study of Peripheral Vestibular System in Users of Personal Listening Devices.","authors":"Teja Deepak Dessai, Kaushlendra Kumar, Rashmi J Bhat","doi":"10.7874/jao.2024.00164","DOIUrl":"10.7874/jao.2024.00164","url":null,"abstract":"<p><strong>Background and objectives: </strong>The widespread use of mobile phones and personal listening devices (PLDs) poses potential health risks, particularly noise-induced hearing loss. Among younger generations, high-volume PLD use is associated with auditory and vestibular system changes. Clinical vestibular testing, including vestibular-evoked myogenic potentials (VEMP) and the video head impulse test (vHIT), may reveal peripheral vestibular impacts from prolonged PLD exposure at volumes over 60%. This study examines VEMP and vHIT results in individuals with normal hearing who have had extended high-volume PLD exposure. Subjects and.</p><p><strong>Methods: </strong>A cross-sectional comparative study was conducted on individuals aged 15-24 years. All the participants had normal pure tone thresholds with \"A\" type tympanogram, present acoustic reflexes, and history of PLD usage. Participants were divided into groups according to PLD exposure of <1 year (group A), 1.1-2 years (group B), 2.1-3 years (group C), and 3.1-4 years (group D). The output sound pressure level (dB SPL) near the tympanic membrane was measured. Furthermore, cervical VEMP, ocular VEMP, and vHIT were assessed.</p><p><strong>Results: </strong>The VEMP and vHIT findings were statistically analyzed and compared across groups. The peak-to-peak amplitudes of VEMP showed a statistically significant difference between groups A and D.</p><p><strong>Conclusions: </strong>Potential subclinical damage to the otolith organs can be associated with increased PLD exposure. No damage to the semi-circular canals was observed as the participants used lower dBA values by the PLDs.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"29 1","pages":"22-30"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Different Types of Contralateral Suppression Tones on Otoacoustic Emission in Children With Autism Spectrum Disorder.","authors":"Fatin Nabilah Jamal, Ahmad Aidil Arafat Dzulkarnain, Nadzirah Ahmad Basri, Sarah Rahmat, Fatin Amira Shahrudin, Mohd Zulfaezal Che Azemin, Shahrul Na'im Sidek, Hazlina Md Yusof, Siti Rafiah Abd Hamid","doi":"10.7874/jao.2024.00353","DOIUrl":"10.7874/jao.2024.00353","url":null,"abstract":"<p><strong>Background and objectives: </strong>Auditory sensory gating deficits are abnormalities in patients with autism spectrum disorder (ASD) that may lead to sensory processing difficulties. It is particularly difficult for children with ASD to distinguish multiple auditory stimuli, which hinders them from focusing on a single auditory stimulus and separating unnecessary sounds. Suppression of otoacoustic emission (OAE) is an approach used to identify sensory gating deficits in the general population, specifically for children with ASD. This study aimed to investigate the suppression effect of various types of sound suppressors to measure their sensory gating capacity in children with ASD. Subjects and.</p><p><strong>Methods: </strong>Twenty children including 10 with ASD and 10 normally developing children aged 6-12 years were recruited for this study. One accessible ear was exposed to transient-evoked OAE, whereas the other was exposed to suppressor tones. Contralateral suppressors included white noise, Quranic recitations, environmental noise, and natural sound. The magnitude of OAE suppression was determined from the difference between the OAE amplitude with and without the masker (in dB sound pressure levels) for all sound types. The sound with the highest suppression effect was determined using effect size calculation and repeated-measures analysis of variance at a 95% confidence level. A high suppression effect may suggest a high sensory gating performance, whereas low suppression may indicate low sensory gating performance.</p><p><strong>Results: </strong>Based on the analysis, the sound with the highest suppression effect was that of the waterfall. The suppression results were supported by descriptive analysis findings and effect-size calculations.</p><p><strong>Conclusions: </strong>This study provides a better understanding of the alternative sound stimuli, besides the standard white noise tone, for the assessment of sensory gating deficits among children with ASD. Sounds with a high suppression effect have the potential to be used as sound therapy interventions for children with ASD as part of rehabilitation and therapy.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"29 1","pages":"49-56"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joy of Electronic Drawing for Operative Notes: Enhancing Surgical Documentation.","authors":"Jong Woo Chung","doi":"10.7874/jao.2024.00682","DOIUrl":"10.7874/jao.2024.00682","url":null,"abstract":"<p><p>This manuscript explores the integration of electronic drawings into surgical operative notes, highlighting their importance in improving the quality and utility of surgical documentation. Operative notes, as essential components of surgical practice, serve various purposes: they detail procedures, provide critical information to healthcare providers, guide treatment planning, and function as legal records. The transition from traditional hand-drawn illustrations to electronic drawings, enabled by the growing adoption of electronic medical record systems, has transformed surgical documentation. This digital approach offers multiple advantages, including better communication among healthcare providers, enhanced patient care, and more effective teaching tools for surgical residents. By delivering clear and intuitive visual depictions of complex procedures, electronic drawings enable faster information retrieval during time-sensitive consultations and promote a shared understanding among healthcare professionals. In conclusion, incorporating electronic drawings into operative notes significantly enriches surgical documentation, ultimately contributing to improved patient outcomes and advancing the discipline of surgery.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"29 1","pages":"64-66"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Approach to the Simulator Sickness Questionnaire.","authors":"Emel Uğur, Asime Kurter, Çağla Aydın, Bahriye Özlem Konukseven","doi":"10.7874/jao.2024.00444","DOIUrl":"10.7874/jao.2024.00444","url":null,"abstract":"<p><strong>Background and objectives: </strong>Virtual reality (VR) applications change the perception of reality, resulting in a feeling of being in a natural environment. The occurrence of cybersickness (CS) when using VR applications is a well-documented side effect, and the Simulator Sickness Questionnaire (SSQ) has been used to assess CS. Considering the speed of VR technology development, CS will likely become a frequently researched and discussed topics in the near future. Therefore, the aim of this study was to conduct a Turkish validity and reliability study and introduce the SSQ to Turkish medical literature. Materials and.</p><p><strong>Methods: </strong>A total of 160 healthy individuals (80 females and 80 males) aged >18 years (28.4±7.2 years) were included in our study. The SSQ was provided to the participants through Google Forms before and after the VR provocation experience and within the scope of the test and retest protocol.</p><p><strong>Results: </strong>The reliability and internal consistency of the questionnaire were observed at a high level (Cronbach's alpha=0.854, Spearman-Brown coefficient r=0.871). Factor analysis was performed and the questionnaire was divided into three subfactors, consistent with the original questionnaire. In the responses obtained from the participants before and after VR provocation, statistically significant differences were observed in 13 of the 16 items in the questionnaire that are related to VR provocation (p<0.05). Statistically, the differences in fatigue, dizziness, and vertigo were greater in females than in males (p<0.05).</p><p><strong>Conclusions: </strong>The Turkish version of the SSQ is an effective tool for measuring the side effects in VR environments. The inclusion of the SSQ in the Turkish literature enables the inclusion of non-English-speaking participants in research, especially for disciplines that consider peripheral and central vestibular disorders.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"29 1","pages":"57-63"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation, Cross-Cultural Adaptation, and Validation of the Eustachian Tube Dysfunction Patient Questionnaire for Assessing Eustachian Tube Dysfunction in Greece.","authors":"Sofia Anastasiadou, Petros Karkos, Jannis Constantinidis, Stefanos Triaridis, George Psillas","doi":"10.7874/jao.2024.00087","DOIUrl":"10.7874/jao.2024.00087","url":null,"abstract":"<p><strong>Background and objectives: </strong>Eustachian tube dysfunction (ETD) is prevalent among patients with ENT disorders, necessitating history-taking, clinical examination, and appropriate investigation for diagnosis. Eustachian Tube Dysfunction Patient Questionnaire (ETDQ-7) is a valuable tool for subjectively assessing symptom severity related to this condition. This study aims to adapt and validate the ETDQ-7 in Greece, ensuring its accuracy and efficacy in outpatient settings. Subjects and.</p><p><strong>Methods: </strong>The ETDQ-7 was translated into Greek following established methodology. Data were collected from 75 Greek patients diagnosed with ETD and 25 control patients without ETD. Participants completed the adapted ETDQ-7 and underwent a clinical examination, with statistical analysis correlating with their ETDQ-7 responses. Statistical analyses were performed to determine the questionnaire's reliability and validity.</p><p><strong>Results: </strong>Internal consistency and item analyses were performed to validate the questionnaire. Face and content validity were confirmed, and patients found the questionnaire easy to administer and complete. Test-retest reliability demonstrated similar internal consistency and a strong correlation between individual items and the total score. Discriminative validity revealed a statistically significant difference between the two patient groups, supporting the usefulness of the Greek version of ETDQ-7 in confirming the diagnosis of ETD.</p><p><strong>Conclusions: </strong>The Greek version of ETDQ-7 proves to be safe and effective for diagnosing ETD in Greek-speaking populations, complementing various investigative methods.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"29 1","pages":"13-21"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}