Fukushima Journal of Medical Science最新文献_第6页

Abdominal organ injury caused by seemingly minor blunt trauma with focal impact in children. 看似轻微的钝性创伤伴局灶性冲击致儿童腹部器官损伤。

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Fukushima Journal of Medical Science Pub Date : 2026-05-02 DOI: 10.5387/fms.26-00006

Takahiro Hosokawa, Yutaka Tanami, Yohei Sanmoto, Tetsuya Ishimaru, Hiroshi Kawashima

{"title":"Abdominal organ injury caused by seemingly minor blunt trauma with focal impact in children.","authors":"Takahiro Hosokawa, Yutaka Tanami, Yohei Sanmoto, Tetsuya Ishimaru, Hiroshi Kawashima","doi":"10.5387/fms.26-00006","DOIUrl":"https://doi.org/10.5387/fms.26-00006","url":null,"abstract":"Abdominal organ injuries in children are usually caused by traffic accidents, which are typically defined as high-energy injuries. We report abdominal organ injury cases not attributed to high-energy blunt trauma but seemingly minor blunt trauma with focal impact.Case 1:A 6-year-old patient was running in a park and slipped one day before. The FAST examination was positive, revealing hepatic injury. Computed tomography demonstrated a massive subcapsular hemorrhage of the liver.Case 2:A 6-year-old patient fell in a room the day before. She experienced trauma to the epigastrium after hitting a water bottle during the fall. The FAST examination was positive, revealing pancreatic injury. Computed tomography was performed and showed a hematoma anterior to the pancreas.Case 3:A 7-year-old girl was practicing bar pullovers one day before. FAST examination was negative;however, targeted ultrasonography revealed a hyperechoic lesion, and computed tomography revealed a hematoma in the duodenal wall.These cases had abdominal organ injury caused by seemingly minor blunt trauma with focal impact. Physical examination and abdominal ultrasound examination, including FAST and targeted ultrasonography, are essential for the early identification of pediatric patients requiring computed tomography.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An exploratory study of human papillomavirus detection in oral rinses from patients with recurrent respiratory papillomatosis. 复发性呼吸道乳头状瘤病患者口腔冲洗液中人乳头状瘤病毒检测的探索性研究。

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-09-02 DOI: 10.5387/fms.25-00026

Shigeyuki Murono, Hiroshi Yoshida, Tomokazu Yoshizaki

{"title":"An exploratory study of human papillomavirus detection in oral rinses from patients with recurrent respiratory papillomatosis.","authors":"Shigeyuki Murono, Hiroshi Yoshida, Tomokazu Yoshizaki","doi":"10.5387/fms.25-00026","DOIUrl":"10.5387/fms.25-00026","url":null,"abstract":"Purpose: Recurrent respiratory papillomatosis (RRP) is associated with low-risk types of human papillomavirus (HPV). With HPV DNA testing, the oral rinse of RRP patients may be a useful liquid biopsy, as previously shown in patients with oropharyngeal cancer.Methods: Oral rinse, along with palatine and pharyngeal tonsil swabs, were collected from seven patients with persistent RRP. HPV DNA detection was performed using polymerase chain reaction, followed by genotype identification.Results: HPV DNA was detected in five of seven oral rinse samples, but not in any palatine or pharyngeal tonsil swabs. HPV6 was identified in four of the five HPV-positive oral rinses, which was consistent with the RRP tissues.Conclusion: HPV DNA can be detected in oral rinses from patients with RRP, suggesting the utility of the oral rinse as a liquid biopsy. In contrast, neither the palatine nor the pharyngeal tonsils were reservoirs of HPV in study patients with RRP.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"177-181"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics of pediatric attention deficit hyperactivity disorder patients born with low birth weight, small for gestational age, or preterm. 低出生体重、小胎龄或早产儿童注意缺陷多动障碍的临床特征

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-08-26 DOI: 10.5387/fms.25-00021

Yukihiko Kawasaki, Yuichi Suzuki, Kyohei Miyazaki, Naoko Suzuki, Megumi Hoshina, Asako Kato, Hiroyuki Morita, Hayato Go

{"title":"Clinical characteristics of pediatric attention deficit hyperactivity disorder patients born with low birth weight, small for gestational age, or preterm.","authors":"Yukihiko Kawasaki, Yuichi Suzuki, Kyohei Miyazaki, Naoko Suzuki, Megumi Hoshina, Asako Kato, Hiroyuki Morita, Hayato Go","doi":"10.5387/fms.25-00021","DOIUrl":"10.5387/fms.25-00021","url":null,"abstract":"Aim: To clarify the frequency and characteristics of patients with attention deficit hyperactivity disorder (ADHD) born with low birth weight (LBW), very low birth weight (VLBW), small for gestational age (SGA), or preterm, we examined the clinical characteristics of ADHD patients.Methods: We collected data for 168 ADHD children, and the patients were retrospectively divided into each group according to birth weight, height, and gestational age.Results: 1) Patients with ADHD born with LBW, VLBW, SGA, or preterm accounted for 10.1%, 3.0%, 3.6%, or 6.5% of all patients, respectively. 2) ADHD-RS scores for hyperactivity disorder and the frequency of patients requiring ADHD drugs in the LBW infant group were higher than those in the non-LBW infant group. 3) ADHD-RS scores for hyperactivity disorder and total in the VLBW infant group were higher than those in the non-VLBW infant (birth weight:1,500-2,500 g) group. 4) The ADHD scores for attention-deficit and trouble score at the most recent follow-up patients born with SGA were higher than for non-SGA patients.Conclusions: These results suggest that it is necessary to pay attention to the appearance of neurodevelopment disorders such as ADHD when monitoring the progress of patients born with LBW or VLBW, and it is important to provide more appropriate management and therapeutic guidance for patients born with VLBW or SGA.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"79-87"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive outcomes of disease awareness information conveyed by high school students to their guardians. 高中生向其监护人传达疾病意识信息的积极效果。

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-11-15 DOI: 10.5387/fms.25-00020

Hiroyuki Terawaki, Masaru Isoyama, Yoshikazu Nemoto, Megumi Nakamura, Lihua Wang, Takafumi Ito

{"title":"Positive outcomes of disease awareness information conveyed by high school students to their guardians.","authors":"Hiroyuki Terawaki, Masaru Isoyama, Yoshikazu Nemoto, Megumi Nakamura, Lihua Wang, Takafumi Ito","doi":"10.5387/fms.25-00020","DOIUrl":"10.5387/fms.25-00020","url":null,"abstract":"Background: This questionnaire-based study aimed to evaluate whether health information conveyed by high school students can encourage their guardians to undergo annual health checks, regardless of their guardians' health literacy (HL) level.Methods: After a lecture to students by an internist on lifestyle-related diseases and chronic kidney disease (CKD), we asked their guardians (n = 1,027) if the students had shared information about the lecture with them and their willingness to participate in an annual health check. We also measured guardian HL using a self-administered questionnaire from which an HL score (minimum=1;maximum=5) could be derived.Results: The median HL score (with interquartile range) of guardians was 3.8 (3.2-4.0). Guardians whose children informed them about CKD were more likely than those who were not informed to plan health checks in the year ahead, regardless of their HL level.Conclusion: Our study demonstrated that the transmission of CKD information from high school students significantly encourages their guardians to schedule health checks, regardless of their HL level.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"141-151"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

2025 Fukushima Medical University International Symposium on the Fukushima Health Management Survey, "Fukushima's lessons for the future: promoting health and responding to disasters." 2025年福岛医科大学福岛健康管理调查国际研讨会，“福岛对未来的教训：促进健康和应对灾害。”

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2026-03-25 DOI: 10.5387/fms.25-00047

Hiroki Shimura, Seiji Yasumura

引用次数: 0

Fundamental study of digital subtraction angiography using dose characteristic analysis of different protocols in lower limb arterial disease. 数字减影血管造影在下肢动脉疾病不同治疗方案剂量特征分析中的基础研究。

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-10-23 DOI: 10.5387/fms.25-00015

Kazuya Kakuta, Koichi Chida, Masamichi Naruse, Shumpei Nemoto, Masamitsu Ikeda, Arifumi Hasegawa

{"title":"Fundamental study of digital subtraction angiography using dose characteristic analysis of different protocols in lower limb arterial disease.","authors":"Kazuya Kakuta, Koichi Chida, Masamichi Naruse, Shumpei Nemoto, Masamitsu Ikeda, Arifumi Hasegawa","doi":"10.5387/fms.25-00015","DOIUrl":"10.5387/fms.25-00015","url":null,"abstract":"AbstractWe clarified the differences between the two pre-set protocols for iodine-digital subtraction angiography (ICM-DSA) and carbon dioxide (CO2)-DSA in terms of radiation exposure to patients and physicians when patients diagnosed with lower extremity artery disease (LEAD) undergo ICM-DSA or CO2-DSA, and identified factors that affect radiation exposure when patients undergo ICM-DSA or CO2-DSA. CO2-and ICM-DSA yielded 149 and 272 vessels in 21 and 49 patients, respectively. Multiple regression analyses revealed strong positive linear correlations between total air kerma (kinetic energy released per unit mass) at the patient entrance reference point (Ka,r), the total kerma area product (KAP), and the total number of acquisitions for ICM-DSA and CO2-DSA, respectively. Compared to Ka,r, there were significant differences in the tube potentials, KAP, and spectral shaping filters in both DSA procedures. The linear correlations between Ka,r and the number of ICM-DSA and CO2-DSA images varied among dose types, with strong linear correlations observed when Ka,r was classified into the above three groups. The X-ray conditions for each DSA image differed, with CO2-DSA using a significantly higher tube potential and different spectral shaping filters compared to ICM-DSA. When performing DSA for LEAD, an optimized protocol for each type of ontrast agent should be used.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"97-107"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Participants' characteristics influencing pupillometry parameters in a community in Japan. 日本某社区参与者特征对瞳孔测量参数的影响

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-10-22 DOI: 10.5387/fms.24-00061

Yuki Ohashi, Yurie Kobashi, Hiromi Kawamata

{"title":"Participants' characteristics influencing pupillometry parameters in a community in Japan.","authors":"Yuki Ohashi, Yurie Kobashi, Hiromi Kawamata","doi":"10.5387/fms.24-00061","DOIUrl":"10.5387/fms.24-00061","url":null,"abstract":"This study aimed to investigate the factors influencing pupil diameter in individuals of a community in Japan, contributing to a broader understanding of the potential of pupillometry as a non-invasive and reliable health indicator. We used a pupillometry device, \"AiLive,\" developed by Mecara Inc. The participants were recruited during a sports festival (SPORTEC 2023), where Mecara Inc. hosted a booth event. The primary outcomes were pupillometry parameters, including the size of pupil parameters and velocity parameters. We analyzed the association between the primary outcome and participant characteristics, including age, sex, the presence of disease, and medication usage. Significant differences were observed between pupillometry parameters and age, sex, and having cataracts, notably pupil size parameters, while velocity parameters remained consistent across groups. These results highlight that the size of pupil parameters could be under-adjusted for age, sex, and the presence of cataracts;in contrast, velocity parameters might have potential as a diagnostic support tool without any adjustment of participants' characteristics.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"89-96"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating preoperative gemcitabine-based chemoradiation for resectable and borderline resectable pancreatic cancer: a phase 1 study. 评估术前以吉西他滨为基础的放化疗对可切除和临界可切除胰腺癌的疗效：一项1期研究。

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-10-23 DOI: 10.5387/fms.25-00013

Naoya Sato, Akira Kenjo, Teruhide Ishigame, Yasuhide Kofunato, Junichiro Haga, Makoto Muto, Shigeyuki Tsukida, Hiroto Chiba, Takayasu Azuma, Takashi Kimura, Shigeru Marubashi

{"title":"Evaluating preoperative gemcitabine-based chemoradiation for resectable and borderline resectable pancreatic cancer: a phase 1 study.","authors":"Naoya Sato, Akira Kenjo, Teruhide Ishigame, Yasuhide Kofunato, Junichiro Haga, Makoto Muto, Shigeyuki Tsukida, Hiroto Chiba, Takayasu Azuma, Takashi Kimura, Shigeru Marubashi","doi":"10.5387/fms.25-00013","DOIUrl":"10.5387/fms.25-00013","url":null,"abstract":"Purpose: Neoadjuvant pancreatic ductal adenocarcinoma (PDAC) treatment is evolving, and chemoradiotherapy (CRT) is emerging as a promising strategy for neoadjuvant therapy. Given the variability in radiotherapy protocols, this study aimed to evaluate the feasibility and safety of gemcitabine-based neoadjuvant chemoradiotherapy.Methods: In this single-arm, phase 1 clinical trial, 31 patients with PDAC were enrolled between April 2016 and August 2019. All patients received preoperative gemcitabine-based chemoradiotherapy with adverse events as the primary endpoint. Multichannel radiation was administered at a total dose of 54 Gy in daily fractions of 1.8 Gy (five fractions per week), which represents a novel aspect of this study.Results: Neoadjuvant therapy was completed in 24 patients, while seven were discontinued due to disease progression. The common adverse events included leukopenia (48.3%), thrombocytopenia (12.9%), and anemia (3.2%). Among the patients who underwent pancreatectomy, the R0 resection rate was 95.8%. Intention-to-treat analysis indicated a 2-year overall survival rate of 49.8% and a 2-year recurrence-free survival rate of 42.4%. High pretreatment CA19-9 levels were identified as predictive factors for overall survival (HR = 28.7, 95% CI:5.00-164.3).Conclusions: Gemcitabine-based neoadjuvant chemoradiotherapy is a feasible and effective approach for achieving high R0 resection rates in resectable and borderline PDAC.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"109-120"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expressive rhythm training improves consistency of rhythm production abilities in patients with schizophrenia. 表达性节奏训练提高精神分裂症患者节奏产生能力的一致性。

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2025-11-27 DOI: 10.5387/fms.25-00008

Yuichi Takahashi, Shinya Fujii, Hiroshi Hoshino, Takeyasu Kakamu, Takatomo Matsumoto, Shuntaro Aoki, Kazuko Kanno, Yuka Ueda, Ken Suzutani, Aya Sato, Yuhei Mori, Tomohiro Wada, Tetsuya Shiga, Shuntaro Itagaki, Hirooki Yabe, Itaru Miura

{"title":"Expressive rhythm training improves consistency of rhythm production abilities in patients with schizophrenia.","authors":"Yuichi Takahashi, Shinya Fujii, Hiroshi Hoshino, Takeyasu Kakamu, Takatomo Matsumoto, Shuntaro Aoki, Kazuko Kanno, Yuka Ueda, Ken Suzutani, Aya Sato, Yuhei Mori, Tomohiro Wada, Tetsuya Shiga, Shuntaro Itagaki, Hirooki Yabe, Itaru Miura","doi":"10.5387/fms.25-00008","DOIUrl":"10.5387/fms.25-00008","url":null,"abstract":"Patients with schizophrenia often experience deficits in timing and rhythm-processing abilities, yet the impact of group-based expressive rhythm training on these functions remains unclear. In this study, we examined the effects of short, daily rhythm training sessions on rhythm perception and production in patients with schizophrenia. Participants (N = 15) in an acute care ward received an average of 18.6 training sessions (15 minutes each). Rhythm abilities were assessed before and after the intervention using the Harvard Beat Assessment Test (H-BAT). Group-level analyses showed no significant changes in the mean values of H-BAT measures. However, correlation analysis revealed that the association between the two rhythm production subtests strengthened considerably post-training (from ρ = -0.539 to ρ = -0.896), indicating greater consistency in rhythm production performance. These findings suggest that expressive rhythm training may help stabilize rhythm output in patients with schizophrenia, even when average performance levels do not significantly change. This improvement in internal consistency provides new insights into the potential mechanisms linking schizophrenia pathology to impaired rhythmic processing and may contribute to the development of novel rehabilitation strategies for this population.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"121-130"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The change in the proportion of positive cases of dengue fever and influenza tests before and after the first case of COVID-19 in Cambodia: a preliminary observational prospective descriptive study. 柬埔寨第一例COVID-19病例前后登革热和流感检测阳性病例比例的变化：一项初步观察性前瞻性描述性研究

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Fukushima Journal of Medical Science Pub Date : 2026-04-01 Epub Date: 2026-01-08 DOI: 10.5387/fms.25-00028

Bun Kimchheng, Takachika Takimoto, Yurie Kobashi, Manabu Okawada

引用次数: 0