Fukushima Journal of Medical Science最新文献_第5页

Serum uric acid level in Japanese university enrollees. 日本大学在校生血清尿酸水平。

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Fukushima Journal of Medical Science Pub Date : 2026-07-01 Epub Date: 2026-01-08 DOI: 10.5387/fms.25-00038

Eisuke Takano, Hiroyuki Terawaki, Satoko Tajirika, Minako Kawamoto, Ryo Horita, Taku Fukao, Takafumi Ito, Junichiro James Kazama, Mayumi Yamamoto

引用次数: 0

Leukocytoclastic vasculitis of the extremities secondary to pancreatic cancer and Escherichia coli abscess; An unusual case of distinct etiologies in the same patient. 胰腺癌和大肠杆菌脓肿继发的四肢白细胞破裂性血管炎；同一患者不同病因的罕见病例。

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Fukushima Journal of Medical Science Pub Date : 2026-07-01 Epub Date: 2026-02-18 DOI: 10.5387/fms.25-00029

Shuhei Yoshida, Eiji Suzuki, Takashi Kanno, Yasuhito Iwao, Hajime Odajima, Yuya Sumichika, Kenji Saito, Takuro Shimbo, Kiyoshi Migita

引用次数: 0

Infectious mononucleosis with ampicillin rash and a positive rapid streptococcal antigen test: a case report. 传染性单核细胞增多症伴氨苄西林疹和快速链球菌抗原试验阳性：1例报告。

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Fukushima Journal of Medical Science Pub Date : 2026-07-01 Epub Date: 2026-02-05 DOI: 10.5387/fms.25-00033

Shuhei Honda, Tomoyuki Watanabe

引用次数: 0

Symptoms experienced by Japanese women seeking treatment for premenstrual symptoms and age-related differences: a cross-sectional study. 日本妇女寻求经前症状治疗的症状和年龄相关差异：一项横断面研究

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Fukushima Journal of Medical Science Pub Date : 2026-06-25 DOI: 10.5387/fms.26-00003

Mariko Ogawa, Kumiko Valckx, Miho Iida, Kiyoshi Takamatsu, Toshifumi Takahashi

{"title":"Symptoms experienced by Japanese women seeking treatment for premenstrual symptoms and age-related differences: a cross-sectional study.","authors":"Mariko Ogawa, Kumiko Valckx, Miho Iida, Kiyoshi Takamatsu, Toshifumi Takahashi","doi":"10.5387/fms.26-00003","DOIUrl":"https://doi.org/10.5387/fms.26-00003","url":null,"abstract":"BackgroundTo improve the management of premenstrual disorders, it is important to understand the prevalence of symptoms and their relationship with age among patients seeking treatment.MethodsIn this retrospective cross-sectional study, we investigated the prevalence of 31 premenstrual symptoms among 199 patients (aged 20-49 years) who visited a gynecology clinic seeking treatment for premenstrual symptoms between November 2022 and May 2023. We also compared symptom prevalence across age groups.ResultsWomen in their 20s comprised the largest group, with 89.9% reporting dysmenorrhea. Fatigue (71.9%) and mood swings (70.9%) were the most prevalent moderate-to-severe symptoms, with psychological symptoms reported more frequently than physical symptoms. Multivariable logistic regression analysis showed that, compared with women in their 20s (reference group), those in their 40s had significantly lower odds of experiencing changes in appetite (adjusted odds ratio [aOR]:0.10), overeating (aOR:0.19), and specific food cravings (aOR:0.09), independent of potential confounders.ConclusionsPsychological symptoms were the most common among gynecological patients seeking treatment for premenstrual disorders. Eating-related symptoms differed by age group. Future longitudinal studies using validated prospective symptom records are warranted.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic dysfunction-associated fatty liver disease and its clinical implications in heart failure. 代谢功能障碍相关的脂肪肝疾病及其在心力衰竭中的临床意义

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Fukushima Journal of Medical Science Pub Date : 2026-06-25 DOI: 10.5387/fms.26-00009

Yoshinori Suzuki, Tomofumi Misaka, Satoshi Okochi, Ryo Ogawara, Yu Sato, Tetsuro Yokokawa, Akihiko Sato, Takeshi Shimizu, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Akiomi Yoshihisa, Yasuchika Takeishi

{"title":"Metabolic dysfunction-associated fatty liver disease and its clinical implications in heart failure.","authors":"Yoshinori Suzuki, Tomofumi Misaka, Satoshi Okochi, Ryo Ogawara, Yu Sato, Tetsuro Yokokawa, Akihiko Sato, Takeshi Shimizu, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Akiomi Yoshihisa, Yasuchika Takeishi","doi":"10.5387/fms.26-00009","DOIUrl":"https://doi.org/10.5387/fms.26-00009","url":null,"abstract":"Background: Heart-liver metabolic crosstalk contributes to heart failure pathophysiology. Metabolic dysfunction-associated fatty liver disease (MAFLD) has been proposed as a new disease entity based on positive metabolic criteria. However, the clinical implications of MAFLD in heart failure remain to be fully elucidated.Methods and results: We enrolled 457 hospitalized patients with symptomatic stage C/D heart failure who underwent abdominal ultrasonography for liver assessment. MAFLD was diagnosed based on the presence of hepatic steatosis and metabolic dysfunction. Overall, 20.1% of patients met the criteria for MAFLD. Patients with MAFLD were younger, had higher tricuspid annular plane systolic excursion (TAPSE), and lower B-type natriuretic peptide levels compared to those without MAFLD. In multivariate logistic regression analysis, TAPSE remained independently associated with MAFLD. During a median follow-up period of 1127 days, Kaplan-Meier analysis demonstrated that patients with MAFLD showed a higher event-free survival from all-cause mortality, but not from composite cardiac events. In multivariable Cox proportional hazards analysis, MAFLD was not independently associated with all-cause mortality.Conclusions: MAFLD was common among the hospitalized patients with heart failure. Although MAFLD appeared to be associated with lower overall mortality, MAFLD was not independently associated with mortality from any cause or future cardiac events.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between post-traumatic stress symptoms and physical and mental conditions of disaster rehabilitation supporters during support activities. 灾后应激症状与灾后重建支持者在支助活动中的身心状况之间的关系。

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Fukushima Journal of Medical Science Pub Date : 2026-06-25 DOI: 10.5387/fms.26-00005

Yuki Watanabe, Jun Nomura, Akie Watanabe, Kenichi Sugano, Yoshinari Funami, Toshimi Sato, Shoji Yabuki, Tetsuo Hayashi

{"title":"Association between post-traumatic stress symptoms and physical and mental conditions of disaster rehabilitation supporters during support activities.","authors":"Yuki Watanabe, Jun Nomura, Akie Watanabe, Kenichi Sugano, Yoshinari Funami, Toshimi Sato, Shoji Yabuki, Tetsuo Hayashi","doi":"10.5387/fms.26-00005","DOIUrl":"https://doi.org/10.5387/fms.26-00005","url":null,"abstract":"Background: Post-traumatic stress disorder (PTSD) has been reported among both survivors and response workers following large natural disasters. The Japan Disaster Rehabilitation Assistance Team (JRAT) provides rehabilitation-focused support;however, few studies have examined post-traumatic stress symptoms (PTSS) among JRAT members. This study investigated the relationship between PTSS and the physical and mental conditions of JRAT members during support activities.Methods: A questionnaire on job type, activity location, sleep quality, meal quality, fatigue, physical symptoms, and psychological symptoms was distributed among 23 JRAT members one month after deployment. PTSS were assessed using the Impact of Event Scale-Revised (IES-R), a self-report screening questionnaire.Results: Overall, 27.3% of participants were classified into the probable PTSS group. Compared with the non-probable group, they reported significantly poorer sleep quality, more physical symptoms, and greater fatigue, whereas psychological symptoms were more common in the non-probable group.Conclusion: Our findings suggest that limited disaster relief experience, discrepancies between expectations and reality, and stress responses during relief activities may be associated with higher PTSS levels among JRAT members, underscoring the importance of comprehensive management of both physical and mental health across deployment phases.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in characteristics and body mass index-SD after guanfacine extended-release administration for ADHD children. 胍法辛缓释后ADHD儿童特征和体重指数sd的变化。

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Fukushima Journal of Medical Science Pub Date : 2026-06-09 DOI: 10.5387/fms.26-00007

Yukihiko Kawasaki, Yuichi Suzuki, Kyohei Miyazaki, Naoko Suzuki, Megumi Hoshina, Hiroyuki Morita, Asako Kato And Hayato Go

{"title":"Changes in characteristics and body mass index-SD after guanfacine extended-release administration for ADHD children.","authors":"Yukihiko Kawasaki, Yuichi Suzuki, Kyohei Miyazaki, Naoko Suzuki, Megumi Hoshina, Hiroyuki Morita, Asako Kato And Hayato Go","doi":"10.5387/fms.26-00007","DOIUrl":"https://doi.org/10.5387/fms.26-00007","url":null,"abstract":"Aim: To clarify the change in characteristics and body mass index standard deviation (BMI-SD) after guanfacine extended-release (GXR) administration for attention-deficit/hyperactivity disorder (ADHD) children, we undertook a clinical survey of ADHD children. Methods:Among 209 pediatric patients with ADHD, two groups were selected:those who patients were received GXR monotherapy (Group 1) and those who were treated with non-pharmacological therapy alone (Group 2). Results:1) BMI-SD scores before and after treatment were 0.56±1.05, 0.76±1.21, respectively, in Group 1 and 0.33±1.18, 0.46±1.15, respectively, in Group 2. The frequency of patients with a BMI-SD score more than 2.0 SD before and at about 2 years after treatment were 7.8% and 13.7%, respectively, in Group 1 and 4.1% and 8.2%, respectively, in Group 2. There were no significant differences between these values before and after treatment. 2) ADHD Rating Scale (ADHD-RS) scores and the improvement rate for each score in Group 1 were higher than those in Group 2. 3) In Group 1, the ADHD-RS scores at the most recent follow-up were significantly lower than those before treatment. Conclusion:GXR administration did not affect obesity in ADHD patients and reduced the characteristics of ADHD, suggesting its usefulness in managing ADHD patients.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative worsening of diastolic function after transcatheter aortic valve implantation is associated with adverse clinical outcomes in patients with heart failure with preserved ejection fraction and severe aortic stenosis. 经导管主动脉瓣置入术后舒张功能恶化与保留射血分数和严重主动脉狭窄的心力衰竭患者的不良临床结局相关。

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Fukushima Journal of Medical Science Pub Date : 2026-05-27 DOI: 10.5387/fms.26-00002

Yu Sato, Akiomi Yoshihisa, Akito Okabe, Naoto Ohashi, Yutaro Sato, Kazuya Sakamoto, Yuuki Muto, Akihiko Sato, Takeshi Shimizu, Tomofumi Misaka, Takashi Kaneshiro, Masayoshi Oikawa, Atsushi Kobayashi, Kazuhiko Nakazato, Yasuchika Takeishi

{"title":"Perioperative worsening of diastolic function after transcatheter aortic valve implantation is associated with adverse clinical outcomes in patients with heart failure with preserved ejection fraction and severe aortic stenosis.","authors":"Yu Sato, Akiomi Yoshihisa, Akito Okabe, Naoto Ohashi, Yutaro Sato, Kazuya Sakamoto, Yuuki Muto, Akihiko Sato, Takeshi Shimizu, Tomofumi Misaka, Takashi Kaneshiro, Masayoshi Oikawa, Atsushi Kobayashi, Kazuhiko Nakazato, Yasuchika Takeishi","doi":"10.5387/fms.26-00002","DOIUrl":"https://doi.org/10.5387/fms.26-00002","url":null,"abstract":"Purpose: This study investigated the prognostic significance of perioperative changes in diastolic function in patients with heart failure with preserved ejection fraction (HFpEF) and severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI).Methods: A total of 123 HFpEF patients (left ventricular ejection fraction ≥50%) with severe AS were evaluated using echocardiography before and within one week after TAVI. Based on changes in diastolic function, patients were classified into the control group with unchanged or improved function (n=105;85.4%) and the worsened group (n=18;14.6%). We compared patient characteristics and prognosis between the two groups.Results: There were no significant differences in age or sex between the groups. The worsened group exhibited lower preoperative peak aortic jet velocity and lower mean aortic valve pressure gradient compared with the control group. Lower preoperative values in these parameters were associated with a higher risk of a worsened diastolic function after TAVI. Eleven major adverse cardiovascular and cerebrovascular events occurred after TAVI. Worsened diastolic function was associated with major adverse cardiovascular and cerebrovascular events (hazard ratio 5.163;p=0.007).Conclusion: Perioperative worsening of diastolic function was associated with poor prognosis in patients with HFpEF and severe AS undergoing TAVI.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical factors associated with arteriovenous fistula patency among Japanese patients undergoing hemodialysis: a single-center retrospective study. 与日本血液透析患者动静脉瘘通畅相关的临床因素：一项单中心回顾性研究

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Fukushima Journal of Medical Science Pub Date : 2026-05-27 DOI: 10.5387/fms.26-00015

Hiroki Ejiri, Kenichi Tanaka, Hiroshi Kimura, Yukiko Kouchi, Naoto Yoshida, Hiroaki Shimmura, Hiroshi Kawaguchi, Akihiko Ozaki, Masaharu Tsubokura, Junichiro James Kazama

{"title":"Clinical factors associated with arteriovenous fistula patency among Japanese patients undergoing hemodialysis: a single-center retrospective study.","authors":"Hiroki Ejiri, Kenichi Tanaka, Hiroshi Kimura, Yukiko Kouchi, Naoto Yoshida, Hiroaki Shimmura, Hiroshi Kawaguchi, Akihiko Ozaki, Masaharu Tsubokura, Junichiro James Kazama","doi":"10.5387/fms.26-00015","DOIUrl":"https://doi.org/10.5387/fms.26-00015","url":null,"abstract":"Introduction: Adequate vascular access is essential for stable hemodialysis treatment. Several clinical factors have been reported to affect arteriovenous fistula (AVF) patency;however, data focusing on Japanese patients remain limited. This study aimed to evaluate one-year AVF patency rates and associated clinical factors in Japanese patients.Methods: We retrospectively analyzed 580 patients who underwent AVF creation at a single center between July 2013 and December 2020. One-year AVF patency rates were estimated using the Kaplan-Meier method, and factors associated with AVF failure were examined using Cox proportional hazards regression.Results: The overall one-year primary, assisted primary, and secondary AVF patency rates were 15.4%, 78.3%, and 79.1%, respectively. In multivariate analyses, older age (adjusted HR 1.02, 95% CI 1.00-1.04), reduced preoperative cardiac function (ejection fraction ≤50%;adjusted HR 1.98, 95% CI 1.20-3.26), and catheter use at dialysis initiation (adjusted HR 1.51, 95% CI 1.02-2.22) were associated with an increased risk of AVF failure.Conclusions: In Japanese patients undergoing hemodialysis, older age, reduced cardiac function, and catheter use at dialysis initiation were factors associated with one-year AVF failure. These findings highlight the importance of minimizing catheter use and assessing cardiovascular status when planning vascular access.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of late retrograde type A aortic dissection after hybrid aortic arch repair. 复合主动脉弓修复术后晚期逆行A型主动脉夹层1例。

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Fukushima Journal of Medical Science Pub Date : 2026-05-02 DOI: 10.5387/fms.25-00044

Keiichi Ishida, Yuki Seto, Shinya Takase

{"title":"A case of late retrograde type A aortic dissection after hybrid aortic arch repair.","authors":"Keiichi Ishida, Yuki Seto, Shinya Takase","doi":"10.5387/fms.25-00044","DOIUrl":"https://doi.org/10.5387/fms.25-00044","url":null,"abstract":"Retrograde type A aortic dissection (RTAD) after thoracic endovascular aortic repair (TEVAR) is a rare but potentially fatal complication. We report a case of very late-onset RTAD occurring 9 years after hybrid aortic arch repair. An 81-year-old man with a history of TEVAR with cervical debranching for subacute thrombosed RTAD, which later developed an ulcer-like projection, presented with dizziness and back pain. Acute RTAD with cardiac tamponade was diagnosed, and emergent ascending aortic replacement with resection of the entry tear-located at the proximal edge of the stent on the lesser curvature-was performed. Postoperatively, the patient required prolonged ventilatory support for respiratory failure and developed pyothorax secondary to aspiration pneumonia. He was ultimately discharged home on postoperative day 188 after rehabilitation. This case underscores the importance of a distinct pathophysiology in late RTAD, in which progressive aortic wall degeneration and biomechanical fatigue over time-rather than procedural factors-may contribute to dissection. Continuous imaging surveillance and strict cardiovascular risk factor management are essential, even in the absence of early complications.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0