Fukushima Journal of Medical Science最新文献

{"title":"Peak IgG antibody titers against SARS-CoV-2 spike protein following immunization with the Pfizer/BioNTech BNT162b2 vaccine","authors":"Y. Kobashi, Y. Shimazu, T. Kawamura, Y. Nishikawa, F. Omata, Y. Kaneko, Tatsuhiko Kodama, M. Tsubokura","doi":"10.5387/fms.2021-28","DOIUrl":"https://doi.org/10.5387/fms.2021-28","url":null,"abstract":"Abstract This study investigated the immune response and outcome of BNT162b2 vaccination among 12 staff at a hospital in Fukushima, Japan. Blood samples were collected from participants before their first vaccination, with subsequent sampling performed during the participants’ work days for six weeks thereafter. Antibody titers peaked 6-13 days after the second vaccination (days 27-34 after the first), followed by a steady decrease. Six males had significantly lower peak antibody titers than six females (p = 0.016 with t-test); the older six (median age 53 years) had lower antibody titers than the younger six (median age 35 years) but without statistical significance (p value=0.24 with t-test).","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"68 1","pages":"67 - 70"},"PeriodicalIF":0.8,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41577952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of laparoscopic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumor.","authors":"Hiroyuki Hanayama,&nbsp;Masanori Katagata,&nbsp;Takahiro Sato,&nbsp;Hiroshi Nakano,&nbsp;Takuro Matsumoto,&nbsp;Takeshi Tada,&nbsp;Yohei Watanabe,&nbsp;Suguru Hayase,&nbsp;Hirokazu Okayama,&nbsp;Tomoyuki Momma,&nbsp;Tsunetaka Kato,&nbsp;Minami Hashimoto,&nbsp;Jun Nakamura,&nbsp;Takuto Hikichi,&nbsp;Zenichiro Saze,&nbsp;Koji Kono","doi":"10.5387/fms.2021-25","DOIUrl":"https://doi.org/10.5387/fms.2021-25","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic and endoscopic cooperative surgery (LECS) is a well-recognized surgical procedure for gastric gastrointestinal stromal tumor (GIST). In this report, we describe the clinical outcomes of LECS procedures for gastric GIST in our institution.</p><p><strong>Methods: </strong>We performed LECS procedures, including classical LECS, inverted LECS, closed LECS, and combination of laparoscopic and endoscopic approaches to neoplasia with non-exposure technique (CLEAN-NET), in 40 gastric intraluminal and intramural type GIST patients, whose tumors were ≤ 50 mm in diameter, between September 2012 and December 2020. The patient background, surgical outcomes, postoperative morbidity and mortality, as well as the tumors' clinicopathological characteristics were analyzed retrospectively.</p><p><strong>Results: </strong>Pathological findings showed that most patients had a low or very low risk of tumor recurrence, while one patient had a high risk according to the modified-Fletcher's classification. The median length of postoperative hospital stay was 7 days. Only one patient had severe postoperative grade III complications according to the Clavien-Dindo (C-D) classification, after closed LECS, but was treated successfully with endoscopic hemostasis for postoperative hemorrhage. The remaining patients treated with LECS did not have severe complications. During the follow-up period (median, 31 months), all patients were disease-free, with no tumor recurrence or metastases.</p><p><strong>Conclusion: </strong>LECS is a safe surgical procedure for gastric intraluminal and intramural type GIST ≤ 50 mm in diameter, with good clinical outcomes.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"68 3","pages":"169-174"},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/1c/2185-4610-68-169.PMC9840883.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10616826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between clinical neck symptoms and various evaluations ofcervical intervertebral disc degeneration by magnetic resonance imaging.","authors":"Haruka Otaki,&nbsp;Koji Otani,&nbsp;Takehiro Watanabe,&nbsp;Miho Sekiguchi,&nbsp;Shin-Ichi Konno","doi":"10.5387/fms.2021-20","DOIUrl":"10.5387/fms.2021-20","url":null,"abstract":"<p><strong>Purpose: </strong>Magnetic resonance imaging (MRI) is widely used to evaluate intervertebral disc degeneration. Recently, various evaluations of cervical disc degeneration using MRI have been conducted, but there is no gold standard. The purpose of this study was to compare the reproducibilities of previously reported classifications for evaluating cervical disc degeneration by MRI and their associations with clinical symptoms.</p><p><strong>Participants and methods: </strong>A total of 582 subjects underwent conventional MRI of the cervical spine. Disc degeneration was assessed in each intervertebral disc from C2/3 to C7/T1 using five different classifications: Matsumoto's grading system, Miyazaki's grading system, Nakashima's grading system, Jacobs' grading system, and Suzuki's grading system. MR images of 30 participants were used, and Cohen's kappa coefficient of agreement of each classification was calculated for intra-observer and inter-observer reliabilities. These five classifications of disc degeneration and changes of vertebral endplates were measured, and associations with clinical symptoms were assessed.</p><p><strong>Results: </strong>Kappa (κ) values of intra-observer agreement were higher for Jacobs' classification, whereas those of inter-observer agreement were higher for Nakashima's and Jacobs' classifications than for other classifications. The prevalences of neck pain and shoulder stiffness were 27.4% and 41.9%, respectively. There were no associations for any classifications of disc degeneration and Modic types with neck pain or shoulder stiffness. Only the presence of Schmorl's nodes was associated with neck pain.</p><p><strong>Conclusion: </strong>At present, there is no specific classification for cervical disc degeneration associated with clinical symptoms. Vertebral endplate changes might be associated with clinical symptoms. It may be necessary to create a new classification for better reproducibility of the evaluation of cervical disc degeneration.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"107-118"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/6c/2185-4610-67-107.PMC8784196.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39643349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between clinical symptoms of lumbar spinal stenosis and MRI axial imaging findings.","authors":"Yuki Fushimi,&nbsp;Koji Otani,&nbsp;Ryoji Tominaga,&nbsp;Masataka Nakamura,&nbsp;Miho Sekiguchi,&nbsp;Shin-Ichi Konno","doi":"10.5387/fms.2021-22","DOIUrl":"https://doi.org/10.5387/fms.2021-22","url":null,"abstract":"<p><strong>Purpose: </strong>In diagnosing lumbar spinal stenosis (LSS), Magnetic Resonance Imaging (MRI) is appropriate to confirm the presence of anatomical stenosis of the spinal canal or compression of the nerve roots. However, it is known that morphological LSS is often present in asymptomatic subjects. There is still controversy about the relationship between anatomical LSS and symptomatic LSS. The aim of this study was to assess the association between qualitative imaging findings on MRI of the lumbar spine and symptomatic LSS.</p><p><strong>Patients and methods: </strong>This was a cross-sectional study of 239 volunteers from an epidemiological survey that included 1,862 participants in total. MRI of the lumbar spine was evaluated in four categories: morphological grading of central stenosis and lateral recess stenosis, presence of the sedimentation sign, and severity of facet joint effusion. The relationship between these morphological evaluations and typical LSS symptoms as assessed by the self-administered, self-reported history questionnaire for lumbar spinal stenosis (LSS-SSHQ) was investigated by multiple logistic regression analysis.</p><p><strong>Results: </strong>The odds ratio of the most severe central stenosis to no stenosis was 15.5 (95%CI: 1.4-164.9). Only the most severe central stenosis was associated with typical LSS symptoms, but not all cases with typical LSS symptoms were due to severe central stenosis.</p><p><strong>Conclusion: </strong>Extreme severe central stenosis was strongly related to typical LSS symptoms. However, although subjects with severe central stenosis showed symptoms suggestive of LSS, these subjects did not always show typical LSS symptoms.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"150-160"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/b4/2185-4610-67-150.PMC8784199.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39718525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical course and background of nasopharyngeal antibiotic-resistant bacteria carriers among preschool children hospitalized for lower respiratory tract infection.","authors":"Aya Takeyama,&nbsp;Kenta Suzuki,&nbsp;Masaki Ito,&nbsp;Masatoki Sato,&nbsp;Koichi Hashimoto,&nbsp;Masahiko Katayose,&nbsp;Mitsuaki Hosoya","doi":"10.5387/fms.2021-07","DOIUrl":"https://doi.org/10.5387/fms.2021-07","url":null,"abstract":"<p><p>AbstractWe investigated the nasopharyngeal microbiota in preschool patients hospitalized with lower respiratory tract infection to clarify the relationships between culturable nasopharyngeal bacteria and prognosis. From 2016 to 2018, nasopharyngeal culture was performed on inpatients under 6 years of age with a lower respiratory tract infection. Among the 1,056 study patients, 1,046 provided nasopharyngeal samples that yielded positive cultures, yielding 1,676 isolated strains. Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, were isolated in 25%, 27%, and 31% of the samples, respectively, and were the major causes of respiratory tract infection in these children. The only factor associated with the isolation of antibiotic-resistant strains from the nasopharynx was daycare attendance, which did not affect clinical severity, such as duration of fever and hospitalization. This study demonstrated that resistant bacteria in the nasopharynx did not affect the severity of lower respiratory tract infection and supports the use of narrow-spectrum antimicrobial agents in accordance with published guidelines when initiating therapy for pediatric patients with community-acquired pneumonia.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"143-149"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/4e/2185-4610-67-143.PMC8784195.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39643348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First trimester heterotopic pregnancy with shock treated laparoscopically, followed by uneventful term pregnancy and normal birth.","authors":"Shinji Nomura,&nbsp;Hyo Kyozuka,&nbsp;Toki Jin,&nbsp;Mimori Fujimori,&nbsp;Daisuke Suzuki,&nbsp;Kenichi Sato,&nbsp;Takashi Imamura,&nbsp;Yasuhisa Nomura","doi":"10.5387/fms.2021-14","DOIUrl":"https://doi.org/10.5387/fms.2021-14","url":null,"abstract":"<p><p>Heterotopic pregnancy (HP), a coexistence of intrauterine and ectopic pregnancies, is extremely rare. Although there have been many reports of maternal outcomes in pregnant women with HP, they have not described fetal neurodevelopmental outcomes and survival. A 30-year-old Japanese woman in early gestation who had undergone two previous cesarean deliveries was transferred to our hospital with vital signs of shock. HP was confirmed by ultrasonography and laparoscopic surgery, and right salpingectomy was performed. At term, a 2,875 g neonate was delivered via cesarean section without any complications.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"168-171"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/21/2185-4610-67-168.PMC8784197.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39570365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a self-administered questionnaire for the screening of cervical myelopathy. Part 2, investigation of its characteristics in surgical cases.","authors":"Hiroshi Kobayashi,&nbsp;Koji Otani,&nbsp;Junichi Handa,&nbsp;Kinshi Kato,&nbsp;Kazuyuki Watanabe,&nbsp;Takuya Nikaido,&nbsp;Shoji Yabuki,&nbsp;Shin-Ichi Konno","doi":"10.5387/fms.2021-03","DOIUrl":"https://doi.org/10.5387/fms.2021-03","url":null,"abstract":"<p><strong>Background: </strong>Our previous report described the development of a self-administered questionnaire to screen patients for cervical myelopathy (SQC). For clinical application, the characteristics of the SQC should be verified.</p><p><strong>Methods: </strong>Participants comprised 129 patients (94 men, 35 women) with cervical myelopathy who underwent operative treatment. SQC score was calculated before surgery and patients were divided into a positive group (score ≥6) and negative group (score <6). Sex, age, pathologies of cervical myelopathy, Japanese Orthopaedic Association (JOA) score, 10-s grip-and-release test (10-s test), grip strength, number of levels decompressed, most cranial level of damage, and presence of diabetes mellitus (DM) were compared between groups.</p><p><strong>Results: </strong>The sensitivity was 89.9% with 116 positive cases and 13 negative cases (10.1%). JOA score was significantly higher and 10-s test and grip strength significantly better in the negative group than in the positive group. No significant differences in sex, age, pathologies of cervical myelopathy, number of spinal levels decompressed, most rostral level of damage, or presence of DM were seen between groups.</p><p><strong>Conclusions: </strong>Screening for cervical myelopathy using SQC had a high sensitivity of 89.9%. However, SQC should be used with caution because it may miss mild cervical myelopathy with low JOA scores.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"102-106"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/54/2185-4610-67-102.PMC8784193.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39540320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secular changes in bone mineral density of adult Japanese women from 1995 to 2013.","authors":"Hiroaki Watanabe, Yasuko Minagawa, Ichiro Suzuki, Kaori Kitamura, Yumi Watanabe, Keiko Kabasawa, Kseniia Platonova, Aya Hinata, Kazutoshi Nakamura","doi":"10.5387/fms.2021-10","DOIUrl":"10.5387/fms.2021-10","url":null,"abstract":"<p><strong>Introduction: </strong>Secular changes in hip fracture incidence have been reported in the last few decades in Japan, but whether long-term bone mineral density (BMD) is also changing is unclear. This study aimed to determine whether BMD of Japanese women has changed over time.</p><p><strong>Methods: </strong>Subjects were 10,649 adult women who underwent BMD measurement in a health check-up population in Niigata, Japan, between 1995 and 2013. BMD of the distal, non-dominant forearm was measured by dual-energy X-ray absorptiometry. Demographic information and BMI were also obtained. Secular trends were determined by linear regression analysis.</p><p><strong>Results: </strong>BMD of subjects in their 40's decreased significantly in the age-adjusted model (P for trend=0.0162), but not in the age- and BMI-adjusted model (P for trend=0.2171). BMD of subjects in their 50's decreased marginally in the age-adjusted model (P for trend=0.0535), but not in the age- and BMI-adjusted model (P for trend=0.6601). BMDs of subjects in their 30's and 60's did not significantly change, while BMIs of subjects in their 40's-60's decreased significantly.</p><p><strong>Conclusions: </strong>A secular decrease in BMD, partly attributed to decreases in BMI, was observed in middle-aged Japanese women from 1995 to 2013. Measures to help maintain suitable BMI will be necessary to prevent a decrease in BMD among women.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"128-134"},"PeriodicalIF":0.7,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/0e/2185-4610-67-128.PMC8784192.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39596501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between participation in sports club activities and decision-making preferences in end-of-life treatment among Japanese elderly people:a cross-sectional study.","authors":"Hideaki Kasuga,&nbsp;Shota Endo,&nbsp;Yusuke Masuishi,&nbsp;Tomoo Hidaka,&nbsp;Takeyasu Kakamu,&nbsp;Keiko Saito,&nbsp;Koichi Abe,&nbsp;Tetsuhito Fukushima","doi":"10.5387/fms.2021-16","DOIUrl":"https://doi.org/10.5387/fms.2021-16","url":null,"abstract":"<p><strong>Introduction: </strong>Decision-making regarding treatment at the end-of-life stage is an important issue for the elderly and their families. Such decision-making may be influenced by activities that promote communication and physical health. The purpose of this study was to examine the association between participation in sports club activities and decision-making regarding life-prolonging treatment among the general community-dwelling Japanese elderly.</p><p><strong>Methods: </strong>In this cross-sectional study, which used stratified random sampling, 1,603 elderly people aged 65 years or older as of January 2016, living in Fukushima prefecture, Japan were enrolled. Data was collected by a self-completed questionnaire (effective response rate: 53.4%). The association of sports club activity participation with a preference for accepting or declining life-prolonging treatment was analyzed by multinomial logistic regression analysis.</p><p><strong>Results: </strong>Of those participating in sports club activities, the results revealed an odds ratios of 1.812 for participants declining life-prolonging treatment (95% CI=1.325 to 2.477) and 1.948 for those who preferred life-prolonging treatment (95% CI=1.160 to 3.271).</p><p><strong>Conclusions: </strong>The present study suggests that participation in sports club activities is associated with articulating decisions about life-prolonging treatment in end-of-life care. Consideration of patient involvement in daily activities in non-medical settings may enhance decision-making for end-of-life care planning.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"135-142"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/d1/2185-4610-67-135.PMC8784194.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39596502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term results of modified bentall procedures: 18-year experience of the flanged technique.","authors":"Takashi Igarashi,&nbsp;Hirono Satokawa,&nbsp;Yoichi Sato,&nbsp;Shinya Takase,&nbsp;Hiroki Wakamatsu,&nbsp;Yuki Seto,&nbsp;Hiroyuki Kurosawa,&nbsp;Masumi Iwai-Takano,&nbsp;Tsuyoshi Fujimiya,&nbsp;Hiroharu Shinjo,&nbsp;Keiichi Ishida,&nbsp;Hitoshi Yokoyama","doi":"10.5387/fms.2021-06","DOIUrl":"https://doi.org/10.5387/fms.2021-06","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the early and late outcomes of the modified Bentall procedure with the flanged technique.</p><p><strong>Methods: </strong>We reviewed the medical records of 63 patients who had undergone root replacement by the modified Bentall procedure at our institute between January 2001 and December 2018. In most cases, we adopted a composite graft constructed with a mechanical valve or bioprosthesis and a Dacron graft by the flanged technique. Since 2011, we have used Valsalva grafts.</p><p><strong>Results: </strong>Mean age 57 ± 16 years, range 16-80, male 43 cases. The mean follow-up was 75 ± 56 months (range 0-216). Through April 1, 2020, we could follow up on 61 cases (97%) within a six-month period. Hospital mortality was 7.9% (4.8% in elective cases). In late follow-up, eight deaths were observed. In the bio-Bentall group (n=26), no deaths or major adverse valve-related events (MARVEs) occurred. In the mechanical Bentall group (n=37), seven cases of MARVEs, including two cerebral hemorrhages and one cerebral embolism, were observed. All patients were free from MARVEs at 5 years post procedure in the bio-Bentall group, and 93.8% and 76.8% were event-free at 5 years and 10 years, respectively, in the mechanical Bentall group.</p><p><strong>Conclusions: </strong>The 18-year results of the modified Bentall procedure were acceptable, providing excellent outcomes in the bio-Bentall group. The flanged technique enabled the use of a larger prosthesis, which may have resulted in good durability with the bio-Bentall procedure.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":"67 3","pages":"119-127"},"PeriodicalIF":0.8,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/04/2185-4610-67-119.PMC8784198.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39596500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}