Fukushima Journal of Medical Science最新文献_第9页

Prognosis of pregnant women with epilepsy and their neonates: a case series study. 癫痫孕妇及其新生儿的预后：一个病例系列研究。

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Fukushima Journal of Medical Science Pub Date : 2025-10-01 Epub Date: 2025-04-26 DOI: 10.5387/fms.24-00048

Hitoshi Masamoto, Momoko Murata, Miya Ooshiro, Morihiko Inamine, Tadakazu Uesato, Hiraku Nagasaki, Masato Hiyane, Masaya Nakamoto, Kouhei Hironaka

{"title":"Prognosis of pregnant women with epilepsy and their neonates: a case series study.","authors":"Hitoshi Masamoto, Momoko Murata, Miya Ooshiro, Morihiko Inamine, Tadakazu Uesato, Hiraku Nagasaki, Masato Hiyane, Masaya Nakamoto, Kouhei Hironaka","doi":"10.5387/fms.24-00048","DOIUrl":"10.5387/fms.24-00048","url":null,"abstract":"Objectives: To explore the outcomes of pregnant women with epilepsy and their neonates, including the incidence of neonatal withdrawal syndrome.Methods: In total, 26 pregnancies in 20 mothers with epilepsy were retrospectively examined for the presence of complications before and during pregnancy, number of antiseizure medications taken, gestational weeks at delivery, mode of delivery, number of seizure episodes during pregnancy and postpartum, neonatal birth weight, Apgar score, pH of the umbilical cord arterial blood, neonatal abnormalities, and neonatal withdrawal syndrome.Results: Overall, 25 of the 26 pregnancies resulted in live births, with 4 cases undergoing premature deliveries.　Ten cases underwent cesarean section, with only one case undergoing cesarean section due to the fear of experiencing seizure during vaginal delivery.　During pregnancy, two cases experienced one seizure episode.　The rate of small for gestational age was 8.0%, and three neonates had congenital abnormalities.　Withdrawal symptoms were observed in 75% of the neonates, but none of them obtained ≥8 points in the withdrawal checklist, the threshold for pharmacotherapy.Conclusions: For women with epilepsy who receive medical management and establish good control prior to pregnancy, child birth may be relatively safe, with a low rate of neonatal withdrawal syndrome requiring pharmacotherapy.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"235-241"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of prolonged severe urinary incontinence after robot-assisted radical prostatectomy: a prospective study. 机器人辅助根治性前列腺切除术后长期严重尿失禁的预测因素：一项前瞻性研究。

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Fukushima Journal of Medical Science Pub Date : 2025-10-01 Epub Date: 2025-04-24 DOI: 10.5387/fms.24-00031

Ryo Tanji, Nobuhiro Haga, Akari Hiraguri, Takahiro Tsumori, Tomoyuki Kumekawa, Shunsuke Yoshioka, Hiroki Natsuya, Yusuke Kirihana, Yusuke Hakozaki, Yu Endo, Kei Yaginuma, Syunta Makabe, Akihisa Hasegawa, Yuki Harigane, Hitomi Imai, Satoru Meguro, Akifumi Onagi, Ruriko Takinami, Kanako Matsuoka, Seiji Hoshi, Emina Kayama, Tomoyuki Koguchi, Junya Hata, Yuichi Sato, Hidenori Akaihata, Masao Kataoka, Soichiro Ogawa, Yoshiyuki Kojima

{"title":"Predictors of prolonged severe urinary incontinence after robot-assisted radical prostatectomy: a prospective study.","authors":"Ryo Tanji, Nobuhiro Haga, Akari Hiraguri, Takahiro Tsumori, Tomoyuki Kumekawa, Shunsuke Yoshioka, Hiroki Natsuya, Yusuke Kirihana, Yusuke Hakozaki, Yu Endo, Kei Yaginuma, Syunta Makabe, Akihisa Hasegawa, Yuki Harigane, Hitomi Imai, Satoru Meguro, Akifumi Onagi, Ruriko Takinami, Kanako Matsuoka, Seiji Hoshi, Emina Kayama, Tomoyuki Koguchi, Junya Hata, Yuichi Sato, Hidenori Akaihata, Masao Kataoka, Soichiro Ogawa, Yoshiyuki Kojima","doi":"10.5387/fms.24-00031","DOIUrl":"10.5387/fms.24-00031","url":null,"abstract":"Objectives: To identify predictors of prolonged severe urinary incontinence after robot-assisted radical prostatectomy (RARP), perioperative clinical parameters were investigated.Methods: Participants were 299 patients who underwent RARP at our institute.　Prolonged severe urinary incontinence was defined as a 1-h (one-hour) pad test >50 g/h and/or use of >3 pads/day at 12 months after RARP.　The cohort was divided into severe and non-severe urinary incontinence groups according to this criterion.　Perioperative clinical parameters were compared between groups to identify predictors for prolonged severe urinary incontinence after RARP.Results: Twenty-seven patients (9.0%) were categorized into the severe urinary incontinence group.　The remaining 272 patients (91.0%) were categorized into the non-severe urinary incontinence group.　Univariate analysis revealed prolonged severe urinary incontinence as significantly associated with older age (P=0.011), high BMI (P=0.001), lymph node dissection (P=0.003), non-preservation of nerves (P=0.039), non-preservation of fascia of the levator ani muscle (P=0.009), and high risk in the D'Amico risk classification (P=0.010).　Multivariate analysis revealed prolonged severe urinary incontinence as significantly correlated with high BMI (P=0.009) and high risk in the D'Amico risk classification (P=0.007).Conclusions: High BMI and D'Amico high-risk status are associated with prolonged severe urinary incontinence after RARP.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"227-234"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A descriptive study of junior residents' encounters with patients presenting various signs, symptoms, and diseases during initial postgraduate general practice/family medicine training in Japan. 日本初级住院医师在初级研究生全科/家庭医学培训期间遇到各种症状、体征和疾病的患者的描述性研究。

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Fukushima Journal of Medical Science Pub Date : 2025-10-01 Epub Date: 2025-04-24 DOI: 10.5387/fms.24-00040

Koki Nakamura, Satoshi Kanke, Atsushi Ishii, Fuyuto Mori, Goro Hoshi, Kanako Kanto, Yoshihiro Toyoda

{"title":"A descriptive study of junior residents' encounters with patients presenting various signs, symptoms, and diseases during initial postgraduate general practice/family medicine training in Japan.","authors":"Koki Nakamura, Satoshi Kanke, Atsushi Ishii, Fuyuto Mori, Goro Hoshi, Kanako Kanto, Yoshihiro Toyoda","doi":"10.5387/fms.24-00040","DOIUrl":"10.5387/fms.24-00040","url":null,"abstract":"Background: In 2020, 29 signs/symptoms as well as 26 diseases/disorders to be encountered during initial postgraduate training were defined in Japan. The purpose of this study was to determine the extent to which junior residents can encounter the signs/symptoms and diseases/disorders during general practice/family medicine training.Methods: Junior residents who participated in general practice/family medicine training for four weeks between 2019 and 2022 were:enrolled in the study. They were each assigned to one of five medical institutions with full-time family doctors in Fukushima Prefecture. The rate of participants who encountered each sign/symptom and disease/disorder, as well as the number of signs/symptoms and diseases/disorders each participant encountered, were defined as outcomes and analyzed descriptively.Results: Ninety junior residents participated in the study. More than half of the participants encountered 11 out of the 29 signs/symptoms, and each participant encountered an average of nine signs/symptoms. As for diseases/disorders, more than half of the participants encountered 11 out of the 26 diseases/disorders, with an average of 11 per participant.Conclusion: General practice/family medicine training provided the junior residents with the opportunity to experience a wide range of signs/symptoms and diseases/disorders.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"203-211"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical practice of a novel molecular diagnostic method for detecting Helicobacter pylori and clarithromycin resistance. 一种新型分子诊断方法检测幽门螺杆菌和克拉霉素耐药性的临床实践。

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Fukushima Journal of Medical Science Pub Date : 2025-10-01 Epub Date: 2025-06-20 DOI: 10.5387/fms.25-00004

Eisuke Kameoka, Takuto Hikichi, Naoki Konno, Hiroki Irie, Yukiko Kanno, Yuto Ishizaki, Sayuri Goto, Masahito Kuroda, Mitsuru Otsuka, Takumi Yanagita, Tsunetaka Kato, Jun Nakamura, Hiromasa Ohira, Kenta Kodama

{"title":"Clinical practice of a novel molecular diagnostic method for detecting Helicobacter pylori and clarithromycin resistance.","authors":"Eisuke Kameoka, Takuto Hikichi, Naoki Konno, Hiroki Irie, Yukiko Kanno, Yuto Ishizaki, Sayuri Goto, Masahito Kuroda, Mitsuru Otsuka, Takumi Yanagita, Tsunetaka Kato, Jun Nakamura, Hiromasa Ohira, Kenta Kodama","doi":"10.5387/fms.25-00004","DOIUrl":"10.5387/fms.25-00004","url":null,"abstract":"Objective: The Smart GeneTM system enables the rapid polymerase chain reaction-based detection of Helicobacter pylori (H. pylori) in gastric juice and determines clarithromycin (CAM) resistance. This study evaluated the clinical utility of the Smart GeneTM system for diagnosing and managing H. pylori infection.Methods: H. pylori diagnosis was obtained using the Smart GeneTM system and the effectiveness of individualized eradication therapy was evaluated. Treatment regimens were chosen based on CAM sensitivity in the Smart GeneTM test.Results: A total of forty-nine patients were assessed. Among them, 28 had H. pylori infection, while 3 had CAM resistance. Seventeen patients underwent H. pylori eradication therapy. Fourteen patients with CAM-sensitive strains underwent eradication therapy with vonoprazan (VPZ), amoxicillin (AMPC), and CAM. Two patients with CAM-resistant strains were treated with VPZ and AMPC, while one received VPZ, AMPC, and metronidazole. The eradication achievement rate was 100%. Of 31 outpatients, 61.5% began H. pylori eradication therapy on the same day as the Smart GeneTM test.Conclusion: Smart GeneTM enables rapid diagnosis of H. pylori infection and the detection of CAM resistance, allowing for personalized eradication regimens.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"257-264"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

De novo overactive bladder after robot-assisted radical prostatectomy is predicted by a high preoperative overactive bladder symptom score, preoperative dyslipidemia, and non-nerve-sparing surgery. 机器人辅助根治性前列腺切除术后新发膀胱过度活动可通过术前膀胱过度活动症状评分高、术前血脂异常和非神经保留手术来预测。

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Fukushima Journal of Medical Science Pub Date : 2025-07-03 Epub Date: 2025-04-11 DOI: 10.5387/fms.24-00057

Hitomi Imai, Hidenori Akaihata, Yuki Harigane, Kei Yaginuma, Satoru Meguro, Ruriko Honda-Takinami, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Yuichi Sato, Soichiro Ogawa, Motohide Uemura, Yoshiyuki Kojima

{"title":"De novo overactive bladder after robot-assisted radical prostatectomy is predicted by a high preoperative overactive bladder symptom score, preoperative dyslipidemia, and non-nerve-sparing surgery.","authors":"Hitomi Imai, Hidenori Akaihata, Yuki Harigane, Kei Yaginuma, Satoru Meguro, Ruriko Honda-Takinami, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Yuichi Sato, Soichiro Ogawa, Motohide Uemura, Yoshiyuki Kojima","doi":"10.5387/fms.24-00057","DOIUrl":"10.5387/fms.24-00057","url":null,"abstract":"Objectives: This study investigated whether preoperative patient characteristics and surgery-related factors affect postoperative de novo overactive bladder (OAB) after robot-assisted radical prostatectomy (RARP), and identified three predictive markers.Methods: Patients without preoperative OAB who underwent RARP at our hospital between February 2013 and October 2020 were included.　At 12 months post-RARP, patients were divided into OAB-free and de novo OAB groups based on the presence of overactive bladder.　Preoperative patient characteristics and surgery-related factors were compared between the two groups.Results: A total of 404 patients were analyzed (OAB-free group, 338; de novo OAB group, 66).　The preoperative Overactive Bladder Symptom Score (OABSS) and the percentage of patients with dyslipidemia were significantly higher in the de novo OAB group than in the OAB-free group (OABSS, 3.2 ± 1.6 points vs 2.1 ± 1.4, P<0.01; dyslipidemia, 45.5% vs 32.0%, P=0.04).　Nerve-sparing surgery was significantly less common in the de novo OAB group (10.6% vs 27.1%, P<0.01).　Preoperative age, blood pressure, BMI, HbA1c, uroflowmetry parameters, prostate volume, operative time and blood loss showed no significant differences between two groups.Conclusions: High preoperative OABSS, preoperative dyslipidemia and non-nerve-sparing surgery may be predictive markers for de novo OAB after RARP.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"169-175"},"PeriodicalIF":0.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular mechanisms leading to gamete fusion. 导致配子融合的分子机制。

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Fukushima Journal of Medical Science Pub Date : 2025-07-03 Epub Date: 2025-03-06 DOI: 10.5387/fms.24-00046

Naokazu Inoue

引用次数: 0

Serum low density lipoprotein cholesterol / high density lipoprotein cholesterol ratio predicts lower urinary tract dysfunction related dyslipidemia. 血清低密度脂蛋白胆固醇/高密度脂蛋白胆固醇比值预测下尿路功能障碍相关的血脂异常。

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Fukushima Journal of Medical Science Pub Date : 2025-07-03 Epub Date: 2025-03-26 DOI: 10.5387/fms.24-00056

Yuki Harigane, Hidenori Akaihata, Kei Yaginuma, Hitomi Imai, Satoru Meguro, Ruriko Takinami, Kanako Matsuoka, Junya Hata, Yuichi Sato, Soichiro Ogawa, Yoshiyuki Kojima

{"title":"Serum low density lipoprotein cholesterol / high density lipoprotein cholesterol ratio predicts lower urinary tract dysfunction related dyslipidemia.","authors":"Yuki Harigane, Hidenori Akaihata, Kei Yaginuma, Hitomi Imai, Satoru Meguro, Ruriko Takinami, Kanako Matsuoka, Junya Hata, Yuichi Sato, Soichiro Ogawa, Yoshiyuki Kojima","doi":"10.5387/fms.24-00056","DOIUrl":"10.5387/fms.24-00056","url":null,"abstract":"Objectives: To investigate the effect of dyslipidemia on the lower urinary tract function by examining the LDL-C/HDL-C ratio in patients without bladder outlet obstruction (BOO).Methods: Patients who underwent urodynamic study before robot-assisted radical prostatectomy were included.　Exclusion criteria were diabetes mellitus (HbA1c > 6.2%) and BOO (Schäfer nomogram obstruction III - V).　The association between the preoperative LDL-C/HDL-C ratio and urodynamic findings were analyzed.　Patients were divided into two groups based on Schäfer nomogram: weak contraction group (W-, W+, N-) and strong contraction group (N+, ST) to assess the relationship between the LDL-C/HDL-C ratio and bladder contraction.Results: A total of 52 patients entered the study.　The LDL-C/HDL-C ratio was 2.4 ± 0.8.　The preoperative international prostate symptom score was mild (6.7 ± 5.6).　Voided volume was significantly positively associated with the LDL-C/HDL-C ratio (P=0.041).　The LDL-C/HDL-C ratio was significantly less in the strong contraction group than in the weak contraction group (P=0.047).　Receiver operating characteristic (ROC) analysis showed a cut-off value of 2.15 for the LDL-C/HDL-C ratio in predicting weak bladder contraction.Conclusions: Dyslipidemia-induced lower urinary tract dysfunction (LUTD) showed less bladder contractility with larger voided volume.　The LDL-C/HDL-C ratio ≥ 2.15 may be a useful marker of dyslipidemia-induced LUTD.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"163-168"},"PeriodicalIF":0.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in perceptions and intentions to engage in various disasters by curriculum and social roles of belonging: A cross-sectional study of japanese medical students. 课程设置和归属社会角色对参与各种灾难的感知和意图的差异：对日本医科学生的横断面研究。

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Fukushima Journal of Medical Science Pub Date : 2025-07-03 Epub Date: 2025-04-01 DOI: 10.5387/fms.24-00049

Kazuki Sugaya, Takeyasu Kakamu, Ken Iseki, Arifumi Hasegawa

{"title":"Differences in perceptions and intentions to engage in various disasters by curriculum and social roles of belonging: A cross-sectional study of japanese medical students.","authors":"Kazuki Sugaya, Takeyasu Kakamu, Ken Iseki, Arifumi Hasegawa","doi":"10.5387/fms.24-00049","DOIUrl":"10.5387/fms.24-00049","url":null,"abstract":"Disasters are becoming more common, and their types are more varied.　This study investigated the extent to which medical students would like to be engaged in different types of disasters to help recruit personnel for future disaster medicine based on a web-based survey.　The study was conducted using existing data.　The results revealed that students' intention to engage in chemical, biological, radiological, nuclear, and explosive (CBRNE) disasters was lower than that for natural and human-made disasters.　Further, differences in the intention to engage and perceptions of disasters were observed.　We hypothesized that the low intention to engage in CBRNE disasters was due, in part, to the fear of unknown hazards and the belief that disaster response was not part of the university's mission.　Thus, each university should train healthcare professionals to imagine the social needs of risk and educate students about their intention to engage.　This can be done by showing them how to respond to disasters in the social context of societal demands in case of future crises.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"177-185"},"PeriodicalIF":0.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19 pandemic on unresectable pancreatic cancer: a regional cohort study in Japan. COVID-19大流行对不可切除胰腺癌的影响：日本的一项区域队列研究

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Fukushima Journal of Medical Science Pub Date : 2025-07-03 Epub Date: 2025-03-06 DOI: 10.5387/fms.24-00011

Rei Suzuki, Hiroyuki Asama, Naoki Konno, Ko Watanabe, Hiromichi Imaizumi, Yuichi Waragai, Mitsuru Sugimoto, Yuki Sato, Hiroki Irie, Hiroshi Shimizu, Kentaro Sato, Tadayuki Takagi, Hiromasa Ohira

{"title":"Impact of COVID-19 pandemic on unresectable pancreatic cancer: a regional cohort study in Japan.","authors":"Rei Suzuki, Hiroyuki Asama, Naoki Konno, Ko Watanabe, Hiromichi Imaizumi, Yuichi Waragai, Mitsuru Sugimoto, Yuki Sato, Hiroki Irie, Hiroshi Shimizu, Kentaro Sato, Tadayuki Takagi, Hiromasa Ohira","doi":"10.5387/fms.24-00011","DOIUrl":"10.5387/fms.24-00011","url":null,"abstract":"Background: The COVID-19 pandemic has had a significant impact on healthcare, including cancer management.　This study aimed to investigate the prognostic impact of the COVID-19 pandemic, throughout its duration, on patient care for pancreatic ductal adenocarcinoma (PDAC).Methods: We collected clinical data of patients with unresectable PDAC who underwent palliative chemotherapy at five medical facilities in Fukushima, Japan.　The patients were divided into two groups: group A (nonpandemic cohort) and group B (pandemic cohort).　Survival analysis was performed for progression-free survival (PFS) and overall survival (OS) via the Kaplan‒Meier method with the log-rank test.Results: In total, 249 patients were selected for the analysis.　Patients in Group B had significantly greater serum CA19-9 levels and proportions of patients selected for combination therapy; however, we did not find significant differences between the two groups in PFS (Group A vs. Group B: 5.6 months vs. 4.4 months, HR = 0.82 (95% CI, 0.6-1.1), p = 0.17) or OS (14.8 months vs. 12.3 months, HR = 0.81 (95% CI, 0.7-1.3), p = 0.81) in the survival analysis.Conclusions: We did not observe a negative impact on the prognosis of patients with unresectable PDAC throughout the COVID-19 pandemic.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"147-153"},"PeriodicalIF":0.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the occurrence and clinical implications of accessory renal arteries: A descriptive study in South Indian cadavers. 探讨副肾动脉的发生和临床意义：在南印度尸体的描述性研究。

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Fukushima Journal of Medical Science Pub Date : 2025-07-03 Epub Date: 2025-03-26 DOI: 10.5387/fms.24-00021

Manju Bhashini Manoharan, Raviraj Kuppusamy, Manickam Subramanian

{"title":"Exploring the occurrence and clinical implications of accessory renal arteries: A descriptive study in South Indian cadavers.","authors":"Manju Bhashini Manoharan, Raviraj Kuppusamy, Manickam Subramanian","doi":"10.5387/fms.24-00021","DOIUrl":"10.5387/fms.24-00021","url":null,"abstract":"Introduction: Renal arteries vary in their number and arrangement.　Accessory renal arteries (ARA), termed by various names in the literature, can arise from different arterial sources and may be single, double, or multiple.　Understanding these variations is essential for various medical procedures.Aim: To determine the presence of ARA in the cadavers of South Indian origin and their origin and termination and to discuss its relevant clinical anatomy.Materials and methods: This descriptive study utilized 36 adult cadavers of South Indian origin aged between 50 and 80 years.　The ARA observed were classified according to their origin and termination.　The Chi-square test was used to determine the variation in the distribution of accessory arteries between the sides.Results: Among the 72 kidneys examined, 27.7% had ARA, with a left-sided preponderance.　Most accessory arteries had an aortic origin and hilar or superior polar termination.　Various forms of accessory arteries were observed, including those entering the anterior surface of the kidney, a rare phenomenon.Conclusion: The incidence of accessory arteries supplying the kidney emphasizes the importance of understanding renal vascular anatomy for clinical practice.　Anatomical variations play a crucial role in selecting donors for renal transplantation and during various renal interventional procedures.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"155-161"},"PeriodicalIF":0.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0