Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery)最新文献_第9页

Neurological manifestations of long COVID: clinical aspects and impact on quality of life 长期COVID的神经学表现:临床方面和对生活质量的影响

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-25 DOI: 10.33920/med-01-2304-03

V. Skvortsov, E. A. Malyakina, G. Malyakin, A. R. Ponomareva, R. Tinaeva, A. V. Kiseleva, A. V. Leskova

{"title":"Neurological manifestations of long COVID: clinical aspects and impact on quality of life","authors":"V. Skvortsov, E. A. Malyakina, G. Malyakin, A. R. Ponomareva, R. Tinaeva, A. V. Kiseleva, A. V. Leskova","doi":"10.33920/med-01-2304-03","DOIUrl":"https://doi.org/10.33920/med-01-2304-03","url":null,"abstract":"Recent studies indicate an extremely high prevalence of long-term neurological manifestations among COVID-19 survivors, with nearly a third of patients diagnosed with neurological or psychiatric disorders in the first 6 months after acute COVID-19. Unlike the acute neurological manifestations of COVID-19, the pathophysiological mechanisms of long COVID-19 remain poorly understood. Several studies have concluded that both the CNS and the PNS are involved in patients with long COVID. The most common neurological symptoms were fatigue, memory/attention deficits, sleep disturbances, and myalgias, with each symptom occurring in one third of patients with prior SARS-CoV-2 infection. The impact of COVID-19 on patients, regardless of severity, extends beyond hospitalization for severe cases to continued deterioration in quality of life, mental health, and employment problems. Doctors' awareness of this condition, strict control of metabolic changes and risk factors for cardiovascular diseases, and effective and safe treatment of identified disorders are the main tasks in the management of patients with this pathology.","PeriodicalId":447580,"journal":{"name":"Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127144819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcranial magnetic stimulation for treatment-resistant depression in patients with residual-organic insufficiency of the central nervous system 经颅磁刺激治疗中枢神经系统残余器质性功能不全患者的难治性抑郁症

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-25 DOI: 10.33920/med-01-2304-01

S. Rangus, B. Tsygankov, A. O. Prosvetov, Yury Yurshev

引用次数: 0

In vitro effect of serum IgGs with oxidoreductase activities of schizophrenic patients on apoptosis level 精神分裂症患者血清氧化还原酶活性对细胞凋亡水平的影响

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-07

L. Smirnova, E. Epimakhova, D. Kazantseva, D. Kamaeva, A. Semke, S. Ivanova

引用次数: 0

Personalized rehabilitation of patients with psychostimulant addiction, taking into account the polymorphism of genes controlling the serotonin system and neuroplastic brain processes 精神兴奋剂成瘾患者的个性化康复，考虑到控制血清素系统和神经可塑性脑过程的基因多态性

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-05

K. N. Poplevchenkov, T. Agibalova, M. Zastrozhin, O. Buzik

{"title":"Personalized rehabilitation of patients with psychostimulant addiction, taking into account the polymorphism of genes controlling the serotonin system and neuroplastic brain processes","authors":"K. N. Poplevchenkov, T. Agibalova, M. Zastrozhin, O. Buzik","doi":"10.33920/med-01-2303-05","DOIUrl":"https://doi.org/10.33920/med-01-2303-05","url":null,"abstract":"The relevance of this study is due to the annual increase in patients with psychostimulant addiction and the lack of evidence-based methods of their rehabilitation within the framework of a personalized approach that takes into account the state of pathogenetic biomarkers of the disease. The aim of the study is to develop a personalized approach to the rehabilitation of patients with psychostimulant addiction, taking into account the polymorphism of genes controlling the work of the serotonin system and neuroplastic processes of the brain. As a result of the study of 325 patients with psychostimulant addiction, polymorphic variants of genes controlling the work of the serotonin system (SLC6A4, HTR2A, HTR2C) and neuroplastic brain processes (BDNF), affecting the formation of dependence and the effectiveness of therapy, were identified. It has been established that polymorphisms in these genes are associated with the effectiveness of motivational work for the rehabilitation program of patients with psychostimulant addiction and the duration of remissions. Based on the results obtained, personalized profiles of patients with psychostimulant addiction, taking into account certain clinical and genetic biomarkers and features of the response of patients to motivational psychotherapy aimed at rehabilitation and the formation of long-term remission, were identified.","PeriodicalId":447580,"journal":{"name":"Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130164767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychopathological aspects of compulsive sexual behavior in males 男性强迫性性行为的精神病理方面

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-03

I. Kan, M. Yagubov

引用次数: 0

Correlations between biochemical and clinical parameters in patients at risk for schizophrenia spectrum disorders 精神分裂症谱系障碍风险患者的生化和临床参数的相关性

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-06

O. Savushkina, I. Boksha, M. Omelchenko, E. Tereshkina, T. Prokhorova, E. Vorobyeva, G. Burbaeva

{"title":"Correlations between biochemical and clinical parameters in patients at risk for schizophrenia spectrum disorders","authors":"O. Savushkina, I. Boksha, M. Omelchenko, E. Tereshkina, T. Prokhorova, E. Vorobyeva, G. Burbaeva","doi":"10.33920/med-01-2303-06","DOIUrl":"https://doi.org/10.33920/med-01-2303-06","url":null,"abstract":"Integrated clinical and biological approach to the early detection of attenuated psychotic symptoms within the frames of affective disorders makes it possible to detect the initial stage of the psychosis development and begin timely therapeutic intervention. The aim of the study was to evaluate the activity of glutamate, glutathione, and energy metabolism enzymes in the blood of patients who are at risk for the development of schizophrenia and to search for clinical and biological correlations. Clinical, psychometric (SOPS and HDRS-21), and biochemical examinations were made in 60 young men aged 16–25 years belonging to the risk group for the development of schizophrenia and in 21 young men from the comparison group without signs of risk of schizophrenia. The control group consisted of 25 healthy young men aged 19–25 years. The activities of cytochrome c oxidase, glutamate dehydrogenase, glutathione reductase, and glutathione-S-transferase were determined in platelets and erythrocytes. Decreased activities of platelet glutamate dehydrogenase, glutathione reductase, and glutathione-S-transferase were observed in all groups of examined patients compared with the control group. In erythrocytes, changed activities of glutathione reductase were observed only in the group of patients without attenuated psychotic symptoms, and glutathione-S-transferase — in the group of patients with attenuated symptoms. The revealed correlations between biochemical and clinical parameters differed in the examined groups of patients. The obtained results reflect the features of the pathogenic mechanisms in the schizophrenia risk group in terms of the activity levels of blood enzymes involved in glutamate, energy, and glutathione metabolism.","PeriodicalId":447580,"journal":{"name":"Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128921367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features of gender identity disorders in schizophrenia spectrum disorders in comparison with transsexualism 精神分裂症谱系障碍与变性欲症的性别认同障碍特征比较

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-02

E. A. Starostina

{"title":"Features of gender identity disorders in schizophrenia spectrum disorders in comparison with transsexualism","authors":"E. A. Starostina","doi":"10.33920/med-01-2303-02","DOIUrl":"https://doi.org/10.33920/med-01-2303-02","url":null,"abstract":"The original study presents the results of a comparative analysis of the clinical, psychopathological, and psychosexual characteristics of gender identity disorders in schizophrenia spectrum disorders and transsexualism. The sample consisted of 120 people with complaints about the inconsistency between gender self-perception and the biological sex, divided into 2 groups: with schizophrenia spectrum disorders and transsexualism. It was found that in the patients with transsexualism, compared to those with schizophrenia spectrum disorders, the age of gender incongruence awareness fell on an earlier age period, and they more often had elements of trans-role behavior in childhood. The respondents with transsexualism more often had experience of living in an associated gender and less often made attempts to adapt in accordance with the gender assigned at birth. The psychosexual development of the patients with transsexualism was generally normative, while the patients with schizophrenia often showed delays in the platonic-erotic stage of libido. It was concluded that in the differential diagnosis of transsexualism and gender identity disorders in schizophrenia spectrum disorders, attention should be paid to such parameters as the presence of signs of gender identity disorders in childhood, age of gender incongruence awareness, experience of life in the associated gender, the presence of dysmorphophobic symptoms not related to sexual characteristics, and the results of a psychological examination of gender identity.","PeriodicalId":447580,"journal":{"name":"Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129422149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of psychogenic factors on the dynamics of suicidal behavior in patients of a psychiatric hospital who have committed suicide or a suicidal attempt 心理因素对精神病院自杀或企图自杀患者自杀行为动态的影响

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-04

S. Vaulin, M. V. Alekseeva, T. V. Morenets

引用次数: 0

Clinical and psychopathological concept of the combined course of recurrent depressive and panic disorders 复发性抑郁和惊恐障碍合并病程的临床和精神病理概念

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-03-18 DOI: 10.33920/med-01-2303-01

I. A. Pastukh, B. Tsygankov

引用次数: 0

Stress and nutrition (Literature review) 应激与营养(文献综述)

Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) Pub Date : 2023-02-08 DOI: 10.33920/med-01-2302-05

V. A. Dudareva, M. Maksimov, I. G. Dyadikova, Ya.A. Korbanov, P. A. Ivashchenko, L.V. Chizhik

引用次数: 0