Advances in Gerontology最新文献_第8页

Transport and Possible Outcome of Lipofuscin in Mouse Myocardium 脂褐素在小鼠心肌中的转运及其可能的结果

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Advances in Gerontology Pub Date : 2022-09-11 DOI: 10.1134/S207905702203016X

L. Wang, C.-Y. Xiao, J.-H. Li, G.-C. Tang, S.-S. Xiao

{"title":"Transport and Possible Outcome of Lipofuscin in Mouse Myocardium","authors":"L. Wang, C.-Y. Xiao, J.-H. Li, G.-C. Tang, S.-S. Xiao","doi":"10.1134/S207905702203016X","DOIUrl":"10.1134/S207905702203016X","url":null,"abstract":"This study was performed to clarify the transfer and final end of lipofuscin substances that have been formed in cardiomyocytes. The hearts of BALB/c mice were obtained for resin embedding and ultra-thin sectioning. The specimens were observed under a transmission electron microscope, and the images were acquired using an XR401 side-insertion device. Lipofuscin granules are found abundantly in myocardial cells. Cardiomyocytes can excrete lipofuscin granules into the myocardial interstitium using capsule-like protrusions that are formed on the sarcolemma. These granules enter the myocardial interstitium and can be de-aggregated to form membrane-like garbage, which can pass from the myocardial stroma into the lumen of the vessel through its walls. Smaller lipofuscin granules can pass through the walls of the vessels and enter the blood vessel lumen through the capillary endothelial cells. When the extended cytoplasmic end of macrophages and fibroblasts fuse with the endothelial cells, the lipofuscin granules or clumps in the myocardial interstitium are transported to the capillary walls, and then, are released into the lumen of the blood vessel by the endothelial cells. The myocardial tissues of mice may have the ability to eliminate the lipofuscin produced in the cardiomyocytes into the myocardial blood circulation.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"12 3","pages":"247 - 263"},"PeriodicalIF":0.6,"publicationDate":"2022-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1134/S207905702203016X.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50473735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ontogenetic Principles of Accelerated Aging and the Prospects for Its Prevention and Treatment 加速衰老的个体发生原理及其防治展望

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Advances in Gerontology Pub Date : 2022-09-11 DOI: 10.1134/S2079057022030080

V. N. Meshchaninov, P. B. Tsyvian, V. S. Myakotnykh, O. P. Kovtun, D. L. Shcherbakov, M. S. Blagodareva

引用次数: 0

Intraoperative and Early Postoperative Risk Factors for the Development of Acute Cerebrovascular Accident in Elderly Patients after Coronary-Artery Bypass Grafting 老年冠状动脉搭桥术后急性脑血管意外发生的术中及术后早期危险因素

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Advances in Gerontology Pub Date : 2022-09-11 DOI: 10.1134/S2079057022030122

T. A. Shnitman, I. G. Trukhanova, S. V. Bulgakova, N. O. Zakharova

引用次数: 0

Involvement of Elderly People in the Processes of Modern Digital Transformations 老年人参与现代数字化转型进程

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Advances in Gerontology Pub Date : 2022-09-11 DOI: 10.1134/S2079057022030043

G. A. Barysheva, E. I. Klemasheva, O. P. Nedospasova, Tran Thi Bich Ngoc, Nguyen Chien Thang

引用次数: 0

Gender and Age Related Macro- and Trace Minerals Estimation Survey among the European North Residents 欧洲北部居民中与性别和年龄相关的宏观和微量矿物质估算调查

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Advances in Gerontology Pub Date : 2022-09-11 DOI: 10.1134/S2079057022030158

I. A. Vinogradova, D. V. Varganova, E. A. Lugovaya

{"title":"Gender and Age Related Macro- and Trace Minerals Estimation Survey among the European North Residents","authors":"I. A. Vinogradova, D. V. Varganova, E. A. Lugovaya","doi":"10.1134/S2079057022030158","DOIUrl":"10.1134/S2079057022030158","url":null,"abstract":"A comparative analysis of the content of elements in hair of the residents of Karelia of different gender and age and of the deviation in the content from reference values typical for residents of the central part of the Russian Federation is carried out. Hair from the occipital part of the head, in which the content of 25 chemical elements is determined, are used as the biological object for elemental analysis. A four-point scale corresponding to the range of deviation of the content of macroelements and microelements from reference values is used to estimate the data obtained. Studying the elemental status in the residents of Karelia demonstrates that the population experiences an excess of toxic elements and a great deficiency of many essential macroelements and microelements. An excess of toxic elements Hg and Pb and a deficiency of essential elements Ca, Zn, Fe, and P is significantly more frequently identified in the hair of 57 test subjects over 60 years old. Such age-related differences in metabolism are established for Si, Na, and K. An imbalance of other macroelements and microelements, such as Co, Mg, I, Cu, Fe, Cr, and Se, is equally typical for residents over 60 years old and for 20–25 year olds (who are a comparison group), which indicates the need for the prevention of regional microelementoses in all strata of the population regardless of age. A Mg and Na deficiency is more often diagnosed in men, while I, Zn, P, and Cr deficiency is found for women. The revealed differences in the elemental composition of hair in the residents of Karelia from reference values typical for residents of the central part of Russia confirm the need for a personalized approach to the replenishment of mineral deficiency taking into account gender and age in the region of residence.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"12 3","pages":"286 - 293"},"PeriodicalIF":0.6,"publicationDate":"2022-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41538541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telerehabilitation of Post-Stroke Patients with Motor Function Disorders: A Review 脑卒中后运动功能障碍患者的远程康复：综述

IF 0.6

Advances in Gerontology Pub Date : 2022-09-11 DOI: 10.1134/S2079057022030109

V. A. Nikolaev, O. G. Safonicheva, A. A. Nikolaev

{"title":"Telerehabilitation of Post-Stroke Patients with Motor Function Disorders: A Review","authors":"V. A. Nikolaev, O. G. Safonicheva, A. A. Nikolaev","doi":"10.1134/S2079057022030109","DOIUrl":"10.1134/S2079057022030109","url":null,"abstract":"Stroke is the main reason for disabilities of increasing geriatric population. It affects brain and motor function domains significantly reducing the life quality. Recent coronavirus pandemic raised a question on changing approaches to deliver post-stroke rehabilitation services to geriatric patients due to their high risk of serious illness. This paper presents an overview of current telerehabilitation approaches for motor function recovery and balance training of post-stroke patients. We used papers from peer-reviewed medical journals on stroke telerehabilitation. The review showed exergames, virtual reality (VR), web-platforms, and applications are extensively used in rehabilitation programs to gain clinical outcomes among geriatric stroke patients. Findings indicate telerehabilitation improves older patients’ functional ability via systematic training, positively affecting their life quality. The treatment therapy of older adults using telerehabilitation can be organized synchronously and asynchronously in home-based environment or in-clinic conditions. Telerehabilitation can be used as complementary therapy or as an alternative to conventional treatment. However, further research is required to test a variety of telerehabilitation systems using larger samples of post-stroke geriatric patients.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"12 3","pages":"339 - 346"},"PeriodicalIF":0.6,"publicationDate":"2022-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42912164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Erratum to: Transport and Possible Outcome of Lipofuscin in Mouse Myocardium 勘误表：脂褐素在小鼠心肌中的转运和可能的结果

IF 0.6

Advances in Gerontology Pub Date : 2022-09-01 DOI: 10.1134/S207905702203016X

L. Wang, C.‐Y. Xiao, J.‐H. Li, Gui-Cheng Tang, Shuo-Shuang Xiao

引用次数: 0

Comparative Analysis of Quality of Life and Attachment Style among Cancer and Dementia Informal Caregivers 癌症和痴呆症非正规照护者生活质量和依恋方式的比较分析

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Advances in Gerontology Pub Date : 2022-07-12 DOI: 10.1134/S2079057022020151

N. Papageorgiou, A. Zygogianni, E. Parpa, E. Tsilika, K. Mystakidou

{"title":"Comparative Analysis of Quality of Life and Attachment Style among Cancer and Dementia Informal Caregivers","authors":"N. Papageorgiou, A. Zygogianni, E. Parpa, E. Tsilika, K. Mystakidou","doi":"10.1134/S2079057022020151","DOIUrl":"10.1134/S2079057022020151","url":null,"abstract":"To record and compare the quality of life and attachment style of dementia and cancer caregivers. This is a comparative prospective cross sectional study. Participants were 45 caregivers of patients with cancer and 45 caregivers of patients with dementia. The study was conducted at a University Hospital and from a Day Centre of Alzheimer Disease and related disorders Association in Athens. Quality of caregivers’ life was measured by the Short Form 36 Health Survey Questionnaire (SF-36) and caregivers’ attachment was evaluated by the Experience in Close Relationships—Short Form (ECR). Caregivers’ age (cancer caregivers’ age Mean = 52.4 and SD ± 12.21, dementia caregivers’ age Mean = 58.4 and SD ± 12.8) differed significantly across diagnostic groups (p < 0.005). Dementia patients were older than cancer patients (dementia patients’ age Mean = 76.8, cancer patients’ age Mean = 65, p < 0.001). Statistically significant difference was found between two groups regarding the duration of the disease. The duration of disease in dementia patients (Mean = 3.14 years) was significantly longer (p = 0.014) than in cancer patients (Mean = 1.23 years). Subscale scores in both instruments (SF-36 and ECR), showed no statistically significant differentiation. Our data showed no statistically significant differentiation in any subscale between cancer and dementia caregivers. However, both caregiver groups noticed remarkably low levels of mental health.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"12 2","pages":"194 - 199"},"PeriodicalIF":0.6,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47064541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptions of Caregiving by Family Caregivers of Older Adults with Dementia in Iran: A Qualitative Study 伊朗家庭照顾者对老年痴呆患者的照顾认知:一项定性研究

IF 0.6

Advances in Gerontology Pub Date : 2022-07-12 DOI: 10.1134/S2079057022020060

A. Farhadi, F. Mohammadi-Shahboulaghi, M. Rassouli, L. Sadeghmoghadam, S. Nazari, M. Froughan

{"title":"Perceptions of Caregiving by Family Caregivers of Older Adults with Dementia in Iran: A Qualitative Study","authors":"A. Farhadi, F. Mohammadi-Shahboulaghi, M. Rassouli, L. Sadeghmoghadam, S. Nazari, M. Froughan","doi":"10.1134/S2079057022020060","DOIUrl":"10.1134/S2079057022020060","url":null,"abstract":"The concept of caring appraisal, which includes positive and negative aspects of care, has been considered as one of the key concepts in caregivers’ studies and is affected by the knowledge, attitudes, values, beliefs, and social norms in their society. In this respect, the perception of family caregivers’ can be studied from a cultural perspective. The aim of the present study was to explore the self-appraisal concept of caring based on the experience of family caregivers of older adults with dementia in Iran. In this qualitative study, data were collected through in-depth, semi-structured interviews. Twelve participants (family caregivers of elderly with dementia) were interviewed between January and September 2016. The transcribed texts were analyzed using inductive qualitative content analysis recommended by Graneheim and Lundman (2004). Six main categories were extrapolated: “Perceived burden,” “Satisfaction with care,” “Personal growth,” “Caregiving gains,” “Philosophy of care” and “Loss and threat.” According to the findings, the family caregivers’ appraisal of their care not only included negative aspects, but also covered a number of positive aspects, which in them the cultural and social factors prevailing in Iranian society played a significant role.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"12 2","pages":"184 - 193"},"PeriodicalIF":0.6,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46984738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abuse and Neglect of Community-Dwelling Older Adults: Index Generation, an Assessment of Intensity, and Implications for Ageing in Place 社区居住老年人的虐待和忽视：指数生成、强度评估及其对老龄化的影响

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Advances in Gerontology Pub Date : 2022-07-12 DOI: 10.1134/S2079057022020035

N. Asiamah, A. K. Conduah, E. Danquah, K. Kouveliotis, R. Eduafo

{"title":"Abuse and Neglect of Community-Dwelling Older Adults: Index Generation, an Assessment of Intensity, and Implications for Ageing in Place","authors":"N. Asiamah, A. K. Conduah, E. Danquah, K. Kouveliotis, R. Eduafo","doi":"10.1134/S2079057022020035","DOIUrl":"10.1134/S2079057022020035","url":null,"abstract":"Abuse and neglect of older adults in the community are a threat to aging in place programs. Recently, some researchers constructed the first scale for assessing elderly abuse and neglect in the neighborhood for research and routine monitoring. This study provides a protocol for generating an index from this tool and assessing the intensity of abuse and neglect. Implications for aging in place are also provided. This study adopted a cross-sectional study and an analysis of secondary data on 515 community-dwelling older adults aged 60 years or higher. Standards in the literature were followed to develop a protocol for generating an index and assessing the intensity of abuse and neglect. The abuse and neglect scale has index scores ranging between 1 and 33, which means that the average score from the index that indicates the intensity of abuse and neglect would fall between this range. We found that abuse and neglect were moderate for the whole scale and the domain “discrimination and harassment” but was high for the domain “neglect and assault.” The dichotomization of the scale showed that high abuse and neglect can be associated with an increase or decrease in social activity. The abuse and neglect scale can be used as a monitoring tool to routinely assess the intensity of elderly abuse and neglect. The dichotomization of the scale can reveal how the highest level of abuse and neglect is affecting behaviors in community-dwelling older adults.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"12 2","pages":"176 - 183"},"PeriodicalIF":0.6,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43868037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0