Journal of Chemical Education最新文献_第4页

Establishing the Effect of Solvent Polarity on Carotenoid Extraction: A Small-Scale Solid–Liquid Extraction and Alkene Identification Experiment for Senior High School Students 溶剂极性对类胡萝卜素提取的影响：高中生小型固液萃取及烯烃鉴定实验

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-12 DOI: 10.1021/acs.jchemed.5c00395

Cheng-Kun Lin*, , , Yu-Jin Huang, , , Yueh-Ling Huang, , , Xin-Shun Chiou, , and , Ci-Yi Zhou,

{"title":"Establishing the Effect of Solvent Polarity on Carotenoid Extraction: A Small-Scale Solid–Liquid Extraction and Alkene Identification Experiment for Senior High School Students","authors":"Cheng-Kun Lin*, , , Yu-Jin Huang, , , Yueh-Ling Huang, , , Xin-Shun Chiou, , and , Ci-Yi Zhou, ","doi":"10.1021/acs.jchemed.5c00395","DOIUrl":"https://doi.org/10.1021/acs.jchemed.5c00395","url":null,"abstract":"We present a small-scale, inquiry-based experiment for senior high school students that explores the effect of solvent polarity on the extraction of carotenoids and the identification of unsaturation through qualitative chemical tests. Using 3 g of diced carrot and three solvents─heptane, ethanol, or water─students conducted solid–liquid extractions, followed by bromine water and potassium permanganate testing. These visual tests detect the presence of unsaturated carotenoids based on color changes associated with electrophilic addition or oxidation reactions. Heptane, a nonpolar solvent, proved most effective in extracting carotenoids, while ethanol showed moderate effectiveness and water was ineffective due to its high polarity. This visually engaging and pedagogically robust experiment reinforces key organic chemistry concepts such as solubility, molecular polarity, and functional group reactivity within a 2 h lab session designed for classroom implementation.","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"102 10","pages":"4570–4577"},"PeriodicalIF":2.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.jchemed.5c00395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolving Mechanistic Understanding of Electrophilic Aromatic Substitution: An Inquiry-Based Computational Chemistry Activity on Anisole Chlorination 亲电芳香族取代的进化机制理解：基于查询的苯甲醚氯化计算化学活性

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-11 DOI: 10.1021/acs.jchemed.5c00718

Li Jiang, , , Yiying Yang, , , Lei Liu, , , Rongxiu Zhu*, , and , Dongju Zhang*,

引用次数: 0

Using Response Surface Methodology To Enhance Limited Data Sets for Machine Learning: A Polyvinyl Butyral Synthesis-Based Chemistry Undergraduate Teaching Case 用响应面方法增强机器学习的有限数据集：一个基于聚乙烯醇丁醛合成的化学本科教学案例

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-11 DOI: 10.1021/acs.jchemed.5c00505

Yingying Liu, , , Liang Gao*, , , Zican Yang, , , Huatang Zhang*, , , Jizhong Chen*, , , Jiayuan Xu, , and , Kai Yin,

{"title":"Using Response Surface Methodology To Enhance Limited Data Sets for Machine Learning: A Polyvinyl Butyral Synthesis-Based Chemistry Undergraduate Teaching Case","authors":"Yingying Liu, , , Liang Gao*, , , Zican Yang, , , Huatang Zhang*, , , Jizhong Chen*, , , Jiayuan Xu, , and , Kai Yin, ","doi":"10.1021/acs.jchemed.5c00505","DOIUrl":"https://doi.org/10.1021/acs.jchemed.5c00505","url":null,"abstract":"This paper presents a novel Course-Based Undergraduate Research Experience (CURE) that addresses a critical challenge in chemical education: teaching students to generate appropriate data for machine learning (ML) applications rather than relying on precurated data sets. Through polyvinyl butyral (PVB) synthesis experiments, 22 third-year chemistry students learned to integrate Response Surface Methodology (RSM) with Support Vector Regression (SVR) algorithms to overcome the inherent data scarcity challenge in undergraduate laboratories. The course guided students through a progressive four-module framework: (1) designing experiments using Central Composite Design principles, (2) conducting PVB synthesis with varied parameters and characterizing products, (3) developing RSM models to establish mathematical relationships between synthesis parameters and material properties, and (4) using these models to generate augmented data sets for ML training. Exit survey results indicate that students self-report significant improvements in their technical competencies, particularly in experimental design (45%, n = 10), machine learning fundamentals (61%, n = 13), and data processing skills (55%, n = 12). Student-developed hybrid RSM-ML models achieved strong predictive performance (R2 values range from 0.78 to 0.95 for testing data sets), significantly outperforming either methodology used independently. This integrated approach prepares students for modern research environments by developing both experimental and computational competencies. The framework is adaptable to other chemical systems.","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"102 10","pages":"4424–4434"},"PeriodicalIF":2.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Droplet-Based Educational Kit for Young Students: Hands-On Experiments from Precipitation Reactions to Magnetic Drug Delivery 为年轻学生提供的以滴为基础的教育套件：从沉淀反应到磁性药物输送的动手实验

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-10 DOI: 10.1021/acs.jchemed.5c00463

Elmira Kohan, , , Elnaz Rashtizadeh, , , Sajjad Aghabalazadeh, , , Fateme Rafiei Atani, , and , Amin Shiralizadeh Dezfuli*,

{"title":"Droplet-Based Educational Kit for Young Students: Hands-On Experiments from Precipitation Reactions to Magnetic Drug Delivery","authors":"Elmira Kohan, , , Elnaz Rashtizadeh, , , Sajjad Aghabalazadeh, , , Fateme Rafiei Atani, , and , Amin Shiralizadeh Dezfuli*, ","doi":"10.1021/acs.jchemed.5c00463","DOIUrl":"https://doi.org/10.1021/acs.jchemed.5c00463","url":null,"abstract":"For high school students, we have created an educational drug delivery kit based on a magnetically sensitive hydrogel (ferrogels). To make it easier for educators to conduct the experiments in a classroom, we concentrated on designing this kit with the simplest reactions and the least amount of equipment. Students learn some common fundamentals in drug delivery, polymer chemistry, and materials science through this course, which is implemented through the POGIL approach as an active learning method. Students’ curiosity in the therapeutic uses of materials is piqued, and they acquire laboratory skills in chemistry via these three-step experiments included in the kit. In addition to learning the basic principles of each experiment, the steps of the experiments take 5–7 h. In the first step, students synthesize Pb(I)2, Fe(OH)2, Fe(OH)3, and Fe3O4 via double replacement precipitation and coprecipitation reactions. This enables students to learn the concepts of these kinds of reactions through simple and attractive experiments. Students make the alginate hydrogel beads in the second part by adding an alginate solution to an aqueous solution of CaCl2 gradually. Lastly, by mixing Fe3O4 nanoparticles into the CaCl2 solution and alginate-D solution containing food dye as a simulated drug, students learn how to create magnetic drug delivery vehicles. The “post-test-only matched control group design” was employed with 50 11th-grade high school students, who were randomly divided into two experimental and control groups. Consequences show that the POGIL-based kit’s training produced noticeably higher test scores compared to the control group, which received traditional chemically designed education. Also, the level of student satisfaction with the above method was 86%.","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"102 10","pages":"4578–4585"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Misconceptions and Insights about Flame Tests 关于火焰测试的误解和见解

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-09 DOI: 10.1021/acs.jchemed.5c00142

Michael A. Duncan*,

引用次数: 0

Caffeine Disclosure in Weight Loss Teas and Its Public Health Implications: An Investigation Using High-Performance Liquid Chromatography 减肥茶中的咖啡因披露及其公共健康意义：使用高效液相色谱法的调查

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-09 DOI: 10.1021/acs.jchemed.5c00593

Heather Knott, , , Cecilia Rivas, , , Julia Barnes, , , Georgina Nicholls, , , Kayley King, , , Rosalynn Quiñones, , and , Anette Casiano-Negroni*,

{"title":"Caffeine Disclosure in Weight Loss Teas and Its Public Health Implications: An Investigation Using High-Performance Liquid Chromatography","authors":"Heather Knott, , , Cecilia Rivas, , , Julia Barnes, , , Georgina Nicholls, , , Kayley King, , , Rosalynn Quiñones, , and , Anette Casiano-Negroni*, ","doi":"10.1021/acs.jchemed.5c00593","DOIUrl":"https://doi.org/10.1021/acs.jchemed.5c00593","url":null,"abstract":"Weight loss supplements have become increasingly popular to help with weight management and health issues. A common ingredient found in these products is caffeine, a “generally recognized as safe” chemical, which can be harmful if taken at high doses or when ingested at the same time as certain medications. Under U.S. regulations, caffeine content must be reported on product labels only when it is added as an ingredient and not when it naturally occurs in herbs. Therefore, the threat posed by undeclared caffeine and the popularity of diet culture make it important to screen weight loss supplements and advise consumers about the risks associated with using such products. In this study, a real-world application laboratory activity for undergraduate students in general, analytical, and instrumental methods courses was developed. Students analyzed randomly selected weight loss teas to identify and quantify caffeine using high-performance liquid chromatography. Caffeine was identified by comparing the relative retention time of their samples to caffeine standards. Linear calibration curves, from an external standard or standard addition method, were used for quantification. Caffeine was detected in five teas where it was not declared on the package and in one where it was declared. For the tea bag where caffeine was disclosed, students quantified 30.7 ± 0.8 mg per bag, an amount that is statistically different than the reported concentration of 35 mg. Students discussed caffeine labeling regulations, considered their implications for public health, and applied chemistry concepts while raising awareness about weight loss supplements.","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"102 10","pages":"4603–4610"},"PeriodicalIF":2.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparing Students for Careers in Sustainable Polymeric Materials with an Advanced Polymer Lab Course 准备学生在可持续高分子材料的职业生涯与先进的高分子实验课程

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-09 DOI: 10.1021/acs.jchemed.5c00564

Kai D. Knight, , , Zachary A. Wood, , and , Megan E. Fieser*,

{"title":"Preparing Students for Careers in Sustainable Polymeric Materials with an Advanced Polymer Lab Course","authors":"Kai D. Knight, , , Zachary A. Wood, , and , Megan E. Fieser*, ","doi":"10.1021/acs.jchemed.5c00564","DOIUrl":"https://doi.org/10.1021/acs.jchemed.5c00564","url":null,"abstract":"The University of Southern California (USC) has recently developed a course in “Properties and Sustainability of Polymers” to enrich the minds of the student body to prepare them to solve the plastics pollution crisis. The course, CHEM462L, was designed to educate students on polymers, how they came to be, how we determine their use in daily life, their effects on the environment, and new directions toward sustainable solutions. From the course, students gain a background in the history and current use of major commercial plastics covering sorting categories #1–7 and begin to think critically about what makes certain plastics so useful for a given application. Beyond learning about industrially produced polymers, students perform in-depth analyses and characterization of various polymers. The course guides students briefly through the process of polymer synthesis followed by unique access to a number of advanced polymer characterization instruments which they use to understand desirable commercial polymer properties as well as the very polymers they made. Later parts of the course begin to dissect ways in which we as individuals can implement more sustainable choices in everyday life and how to address plastic pollution on a governmental and systemic level. In this paper, we describe the development, design, logistics and scheduling of the course and provide initial thoughts and plans for improvement and widespread adoption.","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"102 10","pages":"4441–4448"},"PeriodicalIF":2.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generative AI in Chemistry Education: Current Progress, Pedagogical Values, and the Challenge of Rapid Evolution 化学教育中的生成式人工智能：当前进展、教学价值和快速进化的挑战

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-09 DOI: 10.1021/acs.jchemed.5c01105

Elizabeth Yuriev*, MaryKay Orgill and Thomas Holme,

引用次数: 0

Enhanced Accuracy and Efficiency in Measuring the Rate Constant for Ethyl Acetate Saponification 提高测定乙酸乙酯皂化速率常数的准确性和效率

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-08 DOI: 10.1021/acs.jchemed.5c00554

Wen-Bo Pei, , , Jian-Lan Liu*, , , Jiansheng Wu*, , , Fun Man Fung*, , and , Xiao-Ming Ren,

引用次数: 0

Bridging Artificial Intelligence and Real Intelligence: Self-Scaffolding Computational Modeling with Generative AI in Chemistry 桥接人工智能和真正的智能：化学中的自脚手架计算建模与生成式人工智能

IF 2.9 3区教育学

Journal of Chemical Education Pub Date : 2025-09-08 DOI: 10.1021/acs.jchemed.5c00657

Andreas Haraldsrud*, and , Tor Ole B. Odden,

{"title":"Bridging Artificial Intelligence and Real Intelligence: Self-Scaffolding Computational Modeling with Generative AI in Chemistry","authors":"Andreas Haraldsrud*,  and , Tor Ole B. Odden, ","doi":"10.1021/acs.jchemed.5c00657","DOIUrl":"https://doi.org/10.1021/acs.jchemed.5c00657","url":null,"abstract":"Chemistry education researchers have, for many years, explored different ways of learning chemistry through modeling and open-ended problem-solving. With the emergence of generative artificial intelligence (GenAI) tools such as ChatGPT, students now have access to dynamic scaffolds that can potentially support them in modeling. However, we still know little about how these tools function within such contexts. This study investigates how students in higher education use GenAI to engage in complex computational modeling in chemistry. Using cognitive clinical interviews with think-aloud protocols, the role of GenAI in students’ modeling activities is analyzed through the lens of distributed cognition. The findings from this study reveal four distinct patterns of GenAI use: (1) Leveraging AI to retrieve and clarify information, (2) Using GenAI to test and critique ideas, (3) Outsourcing thinking to the AI, and (4) GenAI output exceeds student understanding. Productive interactions occurred when students actively orchestrated the AI as part of a distributed cognitive system, using it to retrieve, evaluate, and build upon their own reasoning. In contrast, unproductive use occurred when students outsourced thinking to the AI or were overwhelmed by outputs they could not integrate into their existing knowledge. These findings suggest that effective use of GenAI in chemistry education depends not only on technical proficiency, but also on students’ ability to structure prompts, evaluate AI output, and retain control of the problem-solving process. We argue that the use of GenAI should be explicitly addressed in chemistry instruction and propose that students be taught to engage with GenAI as part of a distributed cognitive system─ – retaining executive control, providing appropriate context, and iteratively refining their inquiries─ – to support meaningful engagement and learning in chemistry.","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"102 10","pages":"4255–4266"},"PeriodicalIF":2.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.jchemed.5c00657","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0