Trends in Analytical Chemistry最新文献

{"title":"Observing and analyzing living plants using handheld and miniaturized Raman spectrometers: A review","authors":"Juekun Bai ,&nbsp;Daming Dong","doi":"10.1016/j.trac.2025.118437","DOIUrl":"10.1016/j.trac.2025.118437","url":null,"abstract":"<div><div>Raman spectroscopy, renowned for its molecular fingerprinting ability, has become an indispensable tool in plant detection. The miniaturization of Raman spectrometers further enhances its advantages of non-destructive and rapid analysis, offering new possibilities for in vivo plant detection. In vivo detection is of great significance both for plant physiological research (such as observing chemical signals under early-stage stress and avoiding interference from additional mechanical damage) and for agricultural production (such as real-time monitoring). This paper first introduces the miniaturization of Raman devices. It comprehensively reviews the application of miniaturized Raman spectrometers in plant in vivo detection and then discusses the challenges and potential solutions.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118437"},"PeriodicalIF":12.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stable isotope ratio analysis to determine the geographical origin of timber: A review","authors":"Yuri Gori ,&nbsp;Victor Deklerck ,&nbsp;Federica Camin","doi":"10.1016/j.trac.2025.118448","DOIUrl":"10.1016/j.trac.2025.118448","url":null,"abstract":"<div><div>Illegal logging represents a significant threat to forest ecosystems and their biodiversity. A robust method for tracing the geographical origin of timber allows to verify whether the timber comes from legal sources. A strong candidate is stable isotope ratio analysis, as isotopic ratios vary spatially according to environmental and climatic variables among others. Here, we present a review on H, C, O, N, S and Sr isotope ratios to determine the geographical origin of wood and its components. <em>δ</em>(¹³C) is a good proxy for determining timber provenance on a large scale. <em>δ</em>(¹⁸O) and <em>δ</em>(²H) are strong spatial predictors and generally exhibit altitude and continental effects. <em>δ</em>(¹⁵N), <em>δ</em>(³⁴S) and <em>δ</em>(⁸⁷Sr) are effective for local-scale traceability but less suitable for larger-scale applications. Isoscapes represent a powerful tool for estimating the isotope values of timber across a large spatial range. Advances in methods standardisation, databases and modeling will improve effectiveness, supporting global regulations to protect forests.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118448"},"PeriodicalIF":12.0,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing sustainability in the development of flexible, wearable sensors for the low molecular weight protein detection","authors":"Siew Suan Ng ,&nbsp;Ian Sandall ,&nbsp;Hsin-Cheng Chiu ,&nbsp;Ruey-An Doong","doi":"10.1016/j.trac.2025.118439","DOIUrl":"10.1016/j.trac.2025.118439","url":null,"abstract":"<div><div>Flexible and wearable sensors are at the forefront of health monitoring, particularly the surge in artificial intelligence technologies. The superiority of flexible and wearable sensors over conventional sensors, which are typically composed of metal and semiconductors with restricted stretchability, has boosted biocompatibility and superior real-time monitoring capability. More recently, the biomedical research on low-molecular-weight (LMW) proteins has become increasingly significant, offering diagnostic value but presenting challenges due to their low abundance. This review aims at the discussion on the limitations of traditional and clinical detection methods. The sensing principle of flexible and wearable sensors is concisely addressed, which serves as an overview to connect with the sustainability assessment in the subsequent sections of this review. Subsequently, a compilation of the advancements in flexible and wearable sensors focusing on various aspects of LMW proteins, including materials employed, fabrication techniques, biorecognition components, and transduction processes, is introduced. The potential of contemporary LMW protein detection techniques for substituting conventional methods can be correlated from that point onwards, and the sustainability status of current flexible and wearable sensors has been examined based on critical criteria, including biocompatibility, durability, scalability, reusability, time, energy, and technical requirements. This integrated information is essential as a framework for the future development of LWM protein sensors, identifying the research gap concerning sustainability for the commercialization of these potential sensors and offering enhanced methodology beyond traditional methods.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118439"},"PeriodicalIF":12.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecularly imprinted polymers as artificial catalysts – Recent trends and emerging applications","authors":"Sergey A. Piletsky ,&nbsp;Stanislav S. Piletsky","doi":"10.1016/j.trac.2025.118435","DOIUrl":"10.1016/j.trac.2025.118435","url":null,"abstract":"<div><div>Over the past three decades, molecularly imprinted polymers (MIPs) have emerged as a major research focus in the field of synthetic receptors, driven primarily by their applications in diagnostics. As a by-product of their recognition capabilities, MIPs often exhibit catalytic properties, whether by stabilising transition states, increasing the local concentration of substrates near catalytic sites, or selectively removing products. These reactions can be advantageous not only for diagnostics but also for a range of other applications. Significant efforts have been made to harness this behaviour, aiming to design MIPs that bridge the gap between traditional enzyme catalysis and the biomimetic catalysis offered by synthetic materials. This review highlights advancements in MIP-based catalysis from 2021 to 2025, with a particular focus on recent trends and emerging applications.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118435"},"PeriodicalIF":12.0,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges of molecularly imprinted polymers in impacting environmental monitoring and remediation","authors":"Maryam Arabi ,&nbsp;Abbas Ostovan ,&nbsp;Jiadong Chen ,&nbsp;Yunqing Wang ,&nbsp;Qiaoning Wang ,&nbsp;Xizhen Zhao ,&nbsp;Longwen Fu ,&nbsp;Michael C. Breadmore ,&nbsp;Jaebum Choo ,&nbsp;Lingxin Chen","doi":"10.1016/j.trac.2025.118434","DOIUrl":"10.1016/j.trac.2025.118434","url":null,"abstract":"<div><div>Global concerns about environmental pollution have driven scientists to develop cutting-edge technologies for identification, determination, and remediation. There is a critical need for versatile materials that can sensitively and selectively recognize/degrade these pollutants in complex matrices. Molecularly imprinted polymers (MIPs) can recognize a wide range of target pollutants, making them attractive for use in remediation technologies. However, several technical challenges hinder the effectiveness of MIP-based remediation and environmental protection when practically implemented. This review combines over a decade of practical experience in the synthesis and application of MIPs, to highlight pitfalls and offer insight, solutions and guidance on solving the challenges that need to be overcome for MIPs to deliver enabling solutions for environmental scientists. We highlight molecular imprinting in environmental remediation and monitoring in four separate sections, including pollutant removal, catalytic degradation, sample preparation, and sensing, and propose specific technical challenges to inspire further advances in the field.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118434"},"PeriodicalIF":12.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144917451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Illuminating diverse cellular contents with fluorogenic RNA aptamer-based biosensors: From standardization to innovation","authors":"Jianing Hou ,&nbsp;Xinyu Liu ,&nbsp;Chengwang Miao ,&nbsp;Junyan Wang ,&nbsp;Da Han","doi":"10.1016/j.trac.2025.118436","DOIUrl":"10.1016/j.trac.2025.118436","url":null,"abstract":"<div><div>Capitalizing on the superior programmability of RNA for the precise targeting of diverse targets, fluorogenic RNA aptamer (FRAP)-based biosensors have become powerful tools for synthetic biology. By engineering FRAPs with recognition systems, these biosensors achieve remarkable specificity and sensitivity across detection targets spanning small molecules, proteins, and RNAs. Their unique capacity for real-time visualization of biomolecular dynamics renders them indispensable for living cell imaging applications. In this review, we discuss the generation process of FRAP-based biosensors, propose standardized methods for in vitro performance characterization, and provide a comprehensive analysis of their progress in living cell applications. Additionally, we analyzed strategies for improving biosensor performance in cellular environments. This review provides insights to accelerate the creation of FRAP-based biosensors, targeting diverse molecules, ultimately inspiring dynamic monitoring capabilities in living cell systems for decoding complex cellular responses.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118436"},"PeriodicalIF":12.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing non-noble metal-doped carbon composites for remediation of phthalate esters contaminated water systems","authors":"Shakeel Ahmad ,&nbsp;Muhammad Faheem ,&nbsp;Rongli Yang ,&nbsp;Muhammad Waqas ,&nbsp;Chenghong Ao ,&nbsp;Junhui Zhang ,&nbsp;Gang Chu ,&nbsp;Muhammad Azher Hassan ,&nbsp;Quan Chen ,&nbsp;Bo Pan","doi":"10.1016/j.trac.2025.118432","DOIUrl":"10.1016/j.trac.2025.118432","url":null,"abstract":"<div><div>Conventional noble metal catalysts exhibit excellent electrical conductivity and catalytic activity; however, their high cost, moderate cyclability, and limited availability render them economically impractical for widespread applications. To solve these problems, non-noble metal-doped carbon (Met@C) composites are highly active, economical, structurally and chemically stable, and have been recommended as next-generation materials for removal of emerging contaminants, such as phthalate esters (PAEs). PAEs are commonly used as plasticizers and categorized as low- and high-molecular weight PAEs to understand their differential acute and chronic toxicological profiles. However, they may leach from plastic products, raising environmental concerns regarding their use. A review of PAEs-Met@C interactions will be helpful for targeted design of Met@C for effective PAEs removal. This paper reviews Met@C and its synthesis and environmental applications, specifically PAEs removal from water via adsorption, activation oxidation, photocatalysis, Fenton/Fenton-like processes, and coupled treatment processes and the mechanisms overlaid. It also discusses factors influencing the performance of Met@C for PAEs removal and degradation. To provide mechanistic insights into degradation kinetics and mechanisms of AOPs for PAEs removal, it describes pseudo-1^st-order and 2^nd-order rate constants and radical and nonradical species along with density functional theory and molecular dynamics simulations. To address stability, durability, and scalability of Met@C, it thoroughly explores metal leaching, regeneration, and real-world applications of Met@C for PAEs removal. Before conclusions, it overviews perspectives, future challenges, and opportunities for PAEs removal by Met@C. Overall, this review provides a basis for Met@C to solve technique problems in remediation of PAEs contaminated water systems.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118432"},"PeriodicalIF":12.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144924973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MXene-based composites: A new generation material for the sample preparation and pre-concentration of the traces of organic species in environmental samples: A comprehensive review","authors":"Muhammad Saqaf Jagirani ,&nbsp;Qamar Salamat ,&nbsp;Mustafa Soylak","doi":"10.1016/j.trac.2025.118438","DOIUrl":"10.1016/j.trac.2025.118438","url":null,"abstract":"<div><div>The rapid expansion of industrialization has resulted in escalating environmental pollution, highlighting the urgent need for the development of efficient materials to mitigate harmful toxins. Researchers are increasingly focused on developing novel sustainable materials with unique properties for advanced sample preparation and the monitoring of harmful contaminants, in integration with advancements in material science. MXenes-based materials have garnered significant attention in recent years due to their intriguing physical and chemical properties. MXenes exhibit remarkable adsorption properties, effective sample preparation, and improved pre-concentration efficiency in the extraction of diverse organic contaminants. This review highlights the characteristics of MXene-based composites. This review emphasizes the essential role of MXene-based materials in sample preparation, particularly in solid phase extraction and solid phase microextraction, for the study of trace organic contaminants such as dyes, pharmaceuticals, phenols, and pesticides.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118438"},"PeriodicalIF":12.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144913393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waste-derived sorbents in analytical extraction processes: A review","authors":"Ahmad Reza Bagheri,&nbsp;Ardeshir Shokrollahi,&nbsp;Elham Madani-Nejad","doi":"10.1016/j.trac.2025.118429","DOIUrl":"10.1016/j.trac.2025.118429","url":null,"abstract":"<div><div>Alongside the advancement of analytical extraction methods, analytical chemists have focused their efforts on developing sorbents that adhere to the tenets of green analytical chemistry. Waste-derived sorbents (WDSs) are green, low-priced, and abundant materials with distinguished properties such as facile functionalization and modification, as well as good chemical stability and biocompatibility. WDSs enable the adsorption of various organic molecules through mechanisms including hydrophobic interactions, hydrogen bonding, hydrophilic interactions, and π-π stacking. Hence, WDSs and their composite/modified materials not only can overcome the drawbacks of conventional sorbents and provide novel extracting materials but also inspire the improvement of extraction processes. Therefore, the development of WDSs brings new vigor to extraction technology. This article presents recent advances and progress in applying WDSs as sorbents over the period 2020–2025. In this context: (i) WDSs and their properties will be investigated; (ii) different modified/functionalized WDSs will also be discussed; (iii) it will cover the application of WDSs in solid-phase extraction and solid-phase microextraction techniques; (iv) the potential mechanisms for the extraction of diverse analytes from different samples utilizing WDSs will be examined and discussed; and (v) current trends and issues of WDSs as extraction materials will be analyzed, and prospects will be projected. This article aims to offer insights and perspectives that enhance the understanding of these intriguing materials, focusing on their properties and their present and future roles in analyte extraction techniques.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118429"},"PeriodicalIF":12.0,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144904027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical plasma-based analytical methods and instruments","authors":"Cheng Qian ,&nbsp;Xiangyu Chen ,&nbsp;Guanghui Niu ,&nbsp;Joachim Franzke ,&nbsp;Minghua Liu","doi":"10.1016/j.trac.2025.118431","DOIUrl":"10.1016/j.trac.2025.118431","url":null,"abstract":"<div><div>In modern medicine, instrumental analysis has become an indispensable means in clinical diagnosis. With the progress of science and technology, new detection methods and equipment are constantly emerging. Among them, plasma-based analytical methods and instruments have received extensive attention in clinical application. The review systematically evaluates the role of plasma technology in reshaping clinical analytics. Plasma-based analytical instruments, such as spectrometry and mass spectrometry, have shown great potential in clinical diagnosis, pharmaceutical analysis, and imaging of clinical samples. These technologies offer advantages like high sensitivity, multi-element detection ability, and rapid analysis, making them suitable for various clinical applications. The development of plasma-based analytical methods and instruments is crucial for meeting diverse clinical demands, and future trends include equipment diversification, precision, intelligence, and standardization.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118431"},"PeriodicalIF":12.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144904028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}