{"title":"分子印迹聚合物作为人工催化剂的最新趋势和新应用","authors":"Sergey A. Piletsky , Stanislav S. Piletsky","doi":"10.1016/j.trac.2025.118435","DOIUrl":null,"url":null,"abstract":"<div><div>Over the past three decades, molecularly imprinted polymers (MIPs) have emerged as a major research focus in the field of synthetic receptors, driven primarily by their applications in diagnostics. As a by-product of their recognition capabilities, MIPs often exhibit catalytic properties, whether by stabilising transition states, increasing the local concentration of substrates near catalytic sites, or selectively removing products. These reactions can be advantageous not only for diagnostics but also for a range of other applications. Significant efforts have been made to harness this behaviour, aiming to design MIPs that bridge the gap between traditional enzyme catalysis and the biomimetic catalysis offered by synthetic materials. This review highlights advancements in MIP-based catalysis from 2021 to 2025, with a particular focus on recent trends and emerging applications.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"193 ","pages":"Article 118435"},"PeriodicalIF":12.0000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Molecularly imprinted polymers as artificial catalysts – Recent trends and emerging applications\",\"authors\":\"Sergey A. Piletsky , Stanislav S. Piletsky\",\"doi\":\"10.1016/j.trac.2025.118435\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Over the past three decades, molecularly imprinted polymers (MIPs) have emerged as a major research focus in the field of synthetic receptors, driven primarily by their applications in diagnostics. As a by-product of their recognition capabilities, MIPs often exhibit catalytic properties, whether by stabilising transition states, increasing the local concentration of substrates near catalytic sites, or selectively removing products. These reactions can be advantageous not only for diagnostics but also for a range of other applications. Significant efforts have been made to harness this behaviour, aiming to design MIPs that bridge the gap between traditional enzyme catalysis and the biomimetic catalysis offered by synthetic materials. This review highlights advancements in MIP-based catalysis from 2021 to 2025, with a particular focus on recent trends and emerging applications.</div></div>\",\"PeriodicalId\":439,\"journal\":{\"name\":\"Trends in Analytical Chemistry\",\"volume\":\"193 \",\"pages\":\"Article 118435\"},\"PeriodicalIF\":12.0000,\"publicationDate\":\"2025-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Analytical Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0165993625003036\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993625003036","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Molecularly imprinted polymers as artificial catalysts – Recent trends and emerging applications
Over the past three decades, molecularly imprinted polymers (MIPs) have emerged as a major research focus in the field of synthetic receptors, driven primarily by their applications in diagnostics. As a by-product of their recognition capabilities, MIPs often exhibit catalytic properties, whether by stabilising transition states, increasing the local concentration of substrates near catalytic sites, or selectively removing products. These reactions can be advantageous not only for diagnostics but also for a range of other applications. Significant efforts have been made to harness this behaviour, aiming to design MIPs that bridge the gap between traditional enzyme catalysis and the biomimetic catalysis offered by synthetic materials. This review highlights advancements in MIP-based catalysis from 2021 to 2025, with a particular focus on recent trends and emerging applications.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.