Talanta Open最新文献

{"title":"Analysis of antioxidant properties of pomegranate (Punica granatum L.) Peel extract: Voltammetric, spectrophotometric, and in silico studies as a potential antidiabetic candidate","authors":"Ari Yuniarto ,&nbsp;Junaidin ,&nbsp;Abdul Aziz Setiawan ,&nbsp;Dadang Juanda ,&nbsp;Ardi Ardiansyah ,&nbsp;Vienna Saraswaty","doi":"10.1016/j.talo.2025.100569","DOIUrl":"10.1016/j.talo.2025.100569","url":null,"abstract":"<div><div>Pomegranate (<em>Punica granatum</em> L.) peel, a common byproduct of the agroindustry, contains important antioxidant compounds. This study investigates the antioxidant and antidiabetic properties of pomegranate peel water extract (PPE) using both <em>in vitro</em> and <em>in silico</em> approaches. We evaluated the antioxidant activity using the voltammetric method and DPPH assays, supported by the determination of total phenolic content (TPC) and total flavonoid content (TFC). The direct antioxidant voltammetric evaluation revealed the presence of strong antioxidant compounds with an electrochemical index of 1.12 µA/mV. When the PPE was tested indirectly using K₃Fe(CN)₆ solution, the electrochemical index was increased up to 168.0 µA/mV, indicating a synergistic effect of both electroactive and non-electroactive antioxidant compounds. The DPPH assays also support the presence of strong antioxidant compounds with an IC₅₀ of 17 µg/mL. TPC and TFC values were 8.14 ± 0.373 µg GAE/g dry extract and 1.69 ± 0.003 µg QE/g dry extract, respectively. The antidiabetic potency was analyzed via α-glucosidase inhibition assay, yielding an IC₅₀ of 176.73 µg/mL for PPE. The molecular docking demonstrated that punicalagin, a major bioactive compound present in PPE, exhibited strong binding affinity to α-glucosidase enzyme (−10.42 kcal/mol), surpassing that of acarbose (−10.16 kcal/mol). These findings suggest that PPE is a promising natural source of antioxidant and antidiabetic agents, with potential applications in functional food or therapeutic formulations.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100569"},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative results of tocopherols, sterols, triterpene esters, and lipid degradation products in shea kernels using native or quantifier ion intensity corrected analogue standards","authors":"Kit Granby ,&nbsp;Paula Toma ,&nbsp;Peter Christensen ,&nbsp;Ella Walbeogo ,&nbsp;Yaya Dao ,&nbsp;Tore K Ravn ,&nbsp;Jan H Christensen ,&nbsp;Nikoline J Nielsen","doi":"10.1016/j.talo.2025.100570","DOIUrl":"10.1016/j.talo.2025.100570","url":null,"abstract":"<div><div>In shea kernels from the <em>Vitellaria Paradoxa</em> tree, lipids make up approximately half of the mass. The lipid portion includes a significant proportion of non-glyceridic lipids, also known as unsaponifiable matter (USM). Shea kernel samples from a controlled study in Burkina Faso, investigating local storage conditions in covered soil pits, were analyzed for USM compounds using GC–MS. The quantification was performed using external calibration curves of native (exact compound) or analogue (chemically similar) standards, and relative intensity corrections of quantifier ions were based on EI mass spectra of standards, samples, and MS libraries. The USM compounds amounted to 2.9 ± 0.4 g/100 g (<em>n</em> = 19) of the shea kernel samples. They included three tocopherols, two Δ⁷-sterols, squalene, and triterpenes, where the triterpenes accounted for an average of 98 % of the total quantified beneficial compounds. The triterpenes included four triterpene alcohols, comprising 1 %, ten triterpene acetates, and eight triterpene cinnamates, comprising 97 % of the quantified unsaponifiable extractables. The concentration of the four predominant tetra- and pentacyclic triterpene cinnamate esters were: α-amyrin 907 ± 110 mg/100 g kernels, lupeol 577 ± 73 mg/100 g, butyrospermol 264 ± 44 mg/100 g, and β-amyrin 130 ± 17 mg/100 g. The triterpene acetates were less abundant; the four dominant were of the triterpenes: α-amyrin 268 ± 38 mg/100 g, lupeol 203 ± 39 mg/100 g, butyrospermol 165 ± 32 mg/100 g, and β-amyrin 68 ± 9 mg/100 g. The quantified USM compounds are known to possess antioxidative, anti-inflammatory, and related health effects. Of particular interest are the tetracyclic and pentacyclic triterpene esters due to their exceptionally high levels in shea butter compared to other oils and fats.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100570"},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the role of α- and β-CDs in gold nanoparticle gel-based sensors for Fe³⁺ colorimetric detection","authors":"Agustina Sus Andreani ,&nbsp;Farrah Nurkhaliza ,&nbsp;Muhammad Ridwan ,&nbsp;Salsabila Freya Daniarti ,&nbsp;Lilis Rosmaniar ,&nbsp;Meiyanti Ratna Kumalasari","doi":"10.1016/j.talo.2025.100557","DOIUrl":"10.1016/j.talo.2025.100557","url":null,"abstract":"<div><div>The detection of Fe³⁺ in water samples is critical for mitigating potential harm to environmental and human health. This study presents a comparative investigation of α-cyclodextrin (α-CDs) and β-cyclodextrin (β-CDs) as stabilizing agents in the development of gold nanoparticle (AuNPs)-based gel sensors for Fe³⁺ colorimetric sensing. The AuNPs were synthesized using ortho-hydroxybenzoic acid (o-HBA) as a reducing agent. The red-wine colloidal solutions of AuNPs-o-αCDs and AuNPs-o-βCDs were measured by a UV–Vis spectrophotometer, showing a surface plasmon resonance (SPR) band at 517 nm for both. Field emission scanning electron microscopy – energy dispersive X-ray (FESEM-EDX) analysis revealed well-dispersed AuNPs within the gel matrix. Particle size analysis (PSA) and zeta potential measurements further indicated a smaller particle size and superior colloidal stability in the AuNPs-o-βCDs. The analytical performance of both sensors was evaluated through precision, accuracy (%Recovery), and comparison with atomic absorption spectroscopy (AAS) via <em>t</em>-test assessments. Both sensors demonstrated acceptable precision and accuracy, showing no statistically significant difference from AAS results (<em>p</em> &gt; 0.05). Notably, the gel-AuNPs-o-βCDs sensor exhibited enhanced sensitivity (0.20 mg/L) and faster detection, achieving stable readings within 15 min. In contrast, the gel-AuNPs-o-αCDs had a LoD of 0.57 mg/L and required 20 min for stable readout. Additionally, the gel-AuNPs-o-βCDs demonstrated a higher linear correlation with Fe³⁺ concentration (R² = 0.9999) than the gel-AuNPs-o-αCDs (R² = 0.9994). These findings suggested that β-CDs provide superior stabilization and enhanced performance in the gel-based AuNPs sensors, establishing them as a highly promising candidate for rapid, reliable, and accurate Fe³⁺ detection in tap water.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100557"},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond conventional sensing: A multifunctional benzothiazole-based fluorophore with ESIPT-AIE-ICT synergy for the ultrasensitive determination of tebuconazole in environmental samples","authors":"Asmaa Kamal El-Deen ,&nbsp;Galal Magdy ,&nbsp;Eslam A. Ghaith ,&nbsp;Yhiya Amen ,&nbsp;Ahmed R. Ali","doi":"10.1016/j.talo.2025.100493","DOIUrl":"10.1016/j.talo.2025.100493","url":null,"abstract":"<div><div>Herein, we designed a novel benzothiazole-based fluorophore that combines aggregation-induced emission (AIE), excited-state intramolecular proton transfer (ESIPT), and intramolecular charge transfer (ICT) mechanisms in the behavior of “kill three birds with one stone”. The synthesized fluorophore exhibits a high fluorescence quantum yield and a large Stokes shift (&gt; 200 nm) arising from the synergistic effect of the three mechanisms. This enables effective separation of excitation and emission wavelengths, thereby reducing spectral interference and enhancing precision. The synergistic effect of these mechanisms has been thoroughly investigated and utilized as a multifaceted framework for developing an efficient fluorescent probe capable of determining tebuconazole in environmental water and soil samples. The probe demonstrates remarkable fluorescence quenching in the presence of tebuconazole with outstanding sensitivity over a linear range of 0.32–26.0 µM and a low detection limit of 0.08 µM. Furthermore, the quenching mechanisms were investigated. Static quenching was favored, and theoretical simulation studies confirmed the interaction mechanism. This work elucidates the fluorescence mechanisms, providing an innovative approach for the development of advanced probes with enhanced sensitivity across various fields, such as environmental monitoring and chemical analysis.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100493"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144167606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water","authors":"Zorica Novakovic ,&nbsp;Zorka Z. Vasiljevic ,&nbsp;Maria Vesna Nikolic ,&nbsp;Nenad B. Tadic ,&nbsp;Tijana Djordjevic ,&nbsp;Marko Radovic ,&nbsp;Ivana Gadjanski ,&nbsp;Snežana Papović ,&nbsp;Filip Vlahovic ,&nbsp;Dalibor Stankovic ,&nbsp;Jasmina Vidic","doi":"10.1016/j.talo.2025.100481","DOIUrl":"10.1016/j.talo.2025.100481","url":null,"abstract":"<div><div>Glyphosate is a widely used broad-spectrum herbicide for controlling grassy weeds, despite having potential health hazards. Herein, we report on a solid-state electrochemical sensor based on ZnO nanoparticles (ZnO NPs) for on-site detection of glyphosate. Accordingly, ZnO NPs was drop-cast on the surface of a disposable screen-printed carbon electrode. Eco-friendly ZnO NPs of only 7 nm crystallite sizes were obtained by green sol-gel synthesis using lemon (<em>Citrus limon</em>) waste aqueous extract as the green reducing and capping/stabilizing agent and Zn nitrate precursor as evidenced by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction and diffuse reflectance. SEM confirmed successful electrode functionalization with the synthesized nanoparticles. Under laboratory conditions in acetate buffer (pH 5), the sensor demonstrated excellent selectivity and sensitivity, with a detection limit of 0.648 µM, a wide linear detection range (0.5 µM to 7.5 mM), and a rapid detection time of 30 min. When tested in river water, the sensor achieved a detection limit of 0.96 µM using differential pulse voltammetry. It also exceptionally tolerated interference from similar organophosphorus compounds and ions commonly found in river water. The excellent detection performance of the sensor was attributed to the strong coordination interactions between Zn atoms and phosphonate/carboxylate groups that are enhanced by a hydrogen bond at acidic pH, as determined by chemical calculations. This disposable sensor offers a cost-effective, efficient, and environmentally friendly solution for monitoring glyphosate in water systems.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100481"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144167610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative proteomics analysis of pertussis: Uncovering biomarkers for diagnosis and disease monitoring and insights into pathogenesis","authors":"Yang Xu ,&nbsp;Ke Cao ,&nbsp;Tao Huang ,&nbsp;Yan Zhang ,&nbsp;Cuixia Guo ,&nbsp;Yuxuan Yang ,&nbsp;Yonghong He ,&nbsp;Xiaojun Luo ,&nbsp;Defa Li","doi":"10.1016/j.talo.2025.100521","DOIUrl":"10.1016/j.talo.2025.100521","url":null,"abstract":"<div><div>Pertussis, a highly contagious respiratory disease caused by Bordetella pertussis, remains a significant global health challenge despite vaccination efforts. China has witnessed a resurgence of cases, especially among young children. The diverse clinical manifestations and non-specific symptoms hinder early diagnosis. This study utilized quantitative proteomics analysis to explore differential protein expression in pertussis bacteremia, pneumonia, and non-complicated cases. The key findings include distinct protein profiles across different infection types, which suggest potential biomarkers and offer insights into disease severity and progression. Specifically, proteins such as ADH6 and TTC38 were significantly upregulated in pertussis sepsis, while LRRC42 was downregulated in pertussis pneumonia. During the progression of pertussis sepsis, NCOA3 increased and KCRS decreased from disease onset to improvement, and SAA2 surged in the recovery stage. In comparing pertussis sepsis patients with different outcomes, PTMS, NNMT, and ASSY were downregulated in the deceased patient.These findings enhance our understanding of pertussis pathogenesis, providing crucial insights for the development of more effective vaccines, diagnostics, and treatments, ultimately aiming to reduce the global burden of this infectious disease.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100521"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of molecularly imprinted polymers on graphene oxide-coated screen-printed electrodes for selective immune-sensing of gastric cancer-causing bacteria Helicobacter pylori","authors":"Akshita ,&nbsp;Warren Rosario ,&nbsp;Nidhi Chauhan ,&nbsp;Utkarsh Jain","doi":"10.1016/j.talo.2025.100489","DOIUrl":"10.1016/j.talo.2025.100489","url":null,"abstract":"<div><div><em>Helicobacter pylori (H. pylori)</em> infection continues to be a major public health issue worldwide. The prevalence of <em>H. pylori</em> infection exceeds 50 % worldwide and reaches 70–80 % in developing countries because of inadequate sanitation and restricted healthcare services. The gram-negative bacterium <em>H. pylori</em> hold Group 1 carcinogen status according to the World Health Organization (WHO) because it directly causes chronic gastritis, mucosa-associated lymphoid tissue (MALT), peptic ulcer disease, and gastric adenocarcinoma. This calls for an immediate need for better diagnostic approaches. The gastric mucosa colonization of the bacterium depends on outer membrane proteins, including BabA, OipA, and SabA, which facilitate both adhesion and pathogenicity. The current diagnostic approaches, including biopsy, histology, endoscopy, fecal antigen tests, ELISA, serology, western blotting, urea breath tests, and PCR, face challenges related to complexity, high costs, and low sensitivity. The development of electrochemical biosensors represents a promising diagnostic solution because they provide fast results at affordable prices and portable devices for on-site testing. The incorporation of molecularly imprinted polymers (MIPs) as synthetic receptors with predefined recognition sites for target analytes improves both selectivity and stability of these biosensing platforms. The research introduces an innovative electrochemical biosensor system that detects BabA antibodies (BabA-Ab), which serve as important immunological indicators of <em>H. pylori</em> infection. The sensor platform consists of graphene oxide (GO) that integrates with a BabA-Ab-imprinted polymer matrix. A non-imprinted polymer (NIP) sensor device was constructed simultaneously with the BabA-Ab-imprinted polymer sensor to function as a control reference. The research demonstrates how GO/MIP-based electrochemical sensors can function as advanced clinical diagnostic instruments for fast and precise medical testing.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100489"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144213325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical immunosensor based on screen-printed electrodes modified with gold nanoparticles for highly sensitive detection of TGF-α","authors":"Smriti Gaba,&nbsp;Utkarsh Jain","doi":"10.1016/j.talo.2025.100590","DOIUrl":"10.1016/j.talo.2025.100590","url":null,"abstract":"<div><div>Transforming Growth Factor Alpha (TGF-α) is a critical biomarker associated with various malignancies and pathological conditions, including cancer and other diseases. For efficient diagnosis and therapeutic monitoring, TGF-α in clinical serum must be detected accurately. In this study, we present a highly sensitive and selective electrochemical immunosensor for the detection of TGF-α, leveraging the principles of immunorecognition and advanced signal transduction. The immunosensor was constructed by immobilizing monoclonal anti-TGF-α antibodies via EDC<img>NHS chemistry onto a screen-printed electrode surface modified with gold nanoparticles to enhance electron transfer and provide a high surface area for antibody binding. Gold nanomaterials were characterized by UV–Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), Dynamic light scattering (DLS), and Transmission electron microscopy (TEM) to confirm their morphology and size. Cyclic voltammetry (CV) and X-ray photoelectron spectroscopy (XPS) were employed to characterize the electrode modifications, ensuring stability and functional integrity. The developed sensor demonstrated excellent analytical performance, with a detection limit of 0.35 pg mL⁻¹, a linear range of 1–1000 pg mL⁻¹, and a high sensitivity of 0.051 mA. The immunosensor demonstrated high specificity, with negligible interference from other serum proteins, and robust repeatability. The sensor retained about 98% of its original response after storage at 4°C for 1 week, demonstrating acceptable long-term stability of the functionalized platform. This study underscores the potential of electrochemical immunosensors as a promising platform for the point-of-care diagnostics of TGF-α, enabling timely and accurate disease management. Future advancements may integrate multiplex detection capabilities and real serum analysis for broader clinical applicability and real-world applications.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100590"},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145568176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral flow biosensor-assisted loop-mediated isothermal amplification assay for ultrafast, sensitive detection of African swine fever virus","authors":"Fengming Chen ,&nbsp;Sha Mao ,&nbsp;Renjun Zhang ,&nbsp;Xinggui Yang ,&nbsp;Junfei Huang ,&nbsp;Yingqian Kang ,&nbsp;Feng Hong ,&nbsp;Hong Chen ,&nbsp;Shijun Li ,&nbsp;Yi Wang","doi":"10.1016/j.talo.2025.100581","DOIUrl":"10.1016/j.talo.2025.100581","url":null,"abstract":"<div><div>African swine fever (ASF) is an acute and highly lethal infectious disease caused by African swine fever virus (ASFV). ASF has caused huge economic losses in many countries, and there is still a lack of effective vaccines and treatments. Therefore, the development of rapid and accurate detection methods is crucial for the effective prevention and control of ASF. Here, we developed a novel loop-mediated isothermal amplification (LAMP) combined with nanoparticle-based lateral flow biosensor (LFB) for rapid and specific ASFV detection (ASFV-LAMP-LFB). The ASFV-LAMP-LFB assay was optimized to allow LAMP-LFB results to be visually verified by LFB within 2–5 min, with the entire detection process completed in 35 min and achieving a sensitivity of 0.04 fg/µL. Concurrently, the specificity of the ASFV-LAMP-LFB assay was evaluated using a range of pathogens, yielding 100 % specificity and no cross-reactivity with other porcine pathogens. In addition, the ASFV-LAMP-LFB assay exhibited a 100 % degree of sensitivity and specificity in simulated samples. In conclusion, the ASFV-LAMP-LFB assay established in this study is highly sensitive and specific, and can rapidly and accurately identify ASFV. This study offers a technical complement and support for the detection of ASFV in slaughterhouses, farms, and other grassroots units.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100581"},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145412588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of patterned paper-based sensors for highly efficient formaldehyde detection","authors":"Taeuk Ji ,&nbsp;Gwangbeom Nam ,&nbsp;Shinwon Hwang,&nbsp;Minju Park,&nbsp;Jung Hwal Shin","doi":"10.1016/j.talo.2025.100541","DOIUrl":"10.1016/j.talo.2025.100541","url":null,"abstract":"<div><div>Paper-based sensors are widely used in formaldehyde (FA) sensing in various studies. The development of paper-based sensors with high accuracy and rapid response is important for FA detection. In this study, paper-based FA sensors (PFASs) were developed using a commercial inkjet printer, with filter paper as a substrate. The substrate was coated with a reactive solution containing two pH indicators: thymol blue (TB) and bromophenol blue (BPB), and hydroxylamine sulfate. To evaluate the performance of PFASs, the intensity of the color change caused by FA vapor was detected via colorimetry and optimized with respect to the TB:BPB ratio of the solution and the pattern formation during printing. The optimum TB:BPB ratio was 10:1. The response time decreased as the pattern line width decreased and the pore size increased, and check patterns showed a faster response than those of regularly spaced lines. The sensor was tested in an environment with a relative humidity of 50 ± 5 % at room temperature to ensure consistent experimental conditions, minimizing any potential interference from external factors. The color change of the sensor was visibly noticeable for FA concentrations above 1 ppm. Thus, the proposed technique shows great promise for rapid, high-precision FA detection.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"12 ","pages":"Article 100541"},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145007540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}