Bio-Algorithms and Med-Systems最新文献_第5页

Peptide receptor radionuclide therapy as a tool for the treatment of severe hypoglycemia in patients with primary inoperable insulinoma 肽受体放射性核素疗法作为治疗原发性不能手术胰岛素瘤患者严重低血糖的工具

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-29 DOI: 10.1515/bams-2021-0138

Marta Opalińska, A. Sowa-Staszczak, Ibraheem Al Maraih, A. Gilis-Januszewska, A. Hubalewska-Dydejczyk

{"title":"Peptide receptor radionuclide therapy as a tool for the treatment of severe hypoglycemia in patients with primary inoperable insulinoma","authors":"Marta Opalińska, A. Sowa-Staszczak, Ibraheem Al Maraih, A. Gilis-Januszewska, A. Hubalewska-Dydejczyk","doi":"10.1515/bams-2021-0138","DOIUrl":"https://doi.org/10.1515/bams-2021-0138","url":null,"abstract":"Abstract Objectives Severe hypoglycemia in a course of inoperable insulinoma may be life-threating and often it is not well controlled, even by high doses of diazoxide requiring second line treatment. Among available methods PRRT is characterized by relatively low toxicity and is connected with favorable antitumor effect. The aim of the study was an evaluation of the PRRT effectiveness in control of hypoglycemia in patients with primary inoperable insulinoma. Methods Three patients (female with metastatic insulinoma, male with primary inoperable pancreatic tumor, female with MEN1 syndrome and hepatic metastases) were treated with PRRT due to severe hypoglycemia poorly controlled by diazoxide in course of primary inoperable insulinoma. Results Patient 1 baseline fasting glucose concentration increased from 2.4 mmol/L [3.30–5.60] to 5.9 mmol/L after PRRT. In patient 2 fasting glucose level 2.30 mmol/L increased after PRRT to 7.0 mmol/L, while baseline insulin level initially 31.15 uU/mL [2.6–24.9] decreased to 15.4 uU/mL. In patients 3, baseline fasting glucose level 2.5 mmol/L increased after PRRT to 7.9 mmol/L, and insulin decreased from 57.9 uU/mL to 6.3 uU/mL. In imaging there was partial response (PR) in patient 1 and 2 and stabilization of the tumor size in patient 3. In patient 2 reduction of tumor infiltration let for curative surgery performed 4 months after PPRT. Conclusions PRRT may be effective as a first or second line treatment in management of hypoglycemia for patients with hormonally active inoperable insulinoma.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41287191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

History of radiotherapy in Poland. A brief outline of the problem 波兰放射治疗史。问题的简要概述

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-26 DOI: 10.1515/bams-2021-0137

R. Gryglewski

引用次数: 1

Book review “Process maturity of hospitals and the quality of medical services” by Beata Detyna Beata Detyna的书评《医院的流程成熟度与医疗服务质量》

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-25 DOI: 10.1515/bams-2021-0175

R. Tadeusiewicz

引用次数: 0

Development and implementation of an online platform for curriculum mapping in medical education 医学教育课程制图在线平台的开发与实现

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-23 DOI: 10.1515/bams-2021-0143

J. Majerník, Andrea Kacmarikova, M. Komenda, Andrzej A. Kononowicz, A. Kocurek, Agata Stalmach-Przygoda, Łukasz Balcerzak, Inga Hege, Adrian Ciureanu

{"title":"Development and implementation of an online platform for curriculum mapping in medical education","authors":"J. Majerník, Andrea Kacmarikova, M. Komenda, Andrzej A. Kononowicz, A. Kocurek, Agata Stalmach-Przygoda, Łukasz Balcerzak, Inga Hege, Adrian Ciureanu","doi":"10.1515/bams-2021-0143","DOIUrl":"https://doi.org/10.1515/bams-2021-0143","url":null,"abstract":"Abstract Objectives Nowadays universities face ever-increasing demands on quality of education, which is crucial from perspective of future graduates. In face of the need of constant quality improvements of medical curricula, it is important to seek strategies for their efficient management. The general trend is to develop electronic support tools to streamline the curricular design, analysis and harmonization. Methods Based on the requirements we have identified by the needs analysis among curriculum designers, teachers and managers at five universities involved in the Building Curriculum Infrastructure in Medical Education (BCIME) project, and evidence published in literature on curriculum development, we have developed methodological guidelines on curriculum innovations and a software-based tools that help manage, map and analyse curricula in the medical and healthcare study fields. Results In this paper, we share our experiences with building and implementation of EDUportfolio, an online platform developed within our consortium and intended to facilitate harmonisation and optimisation of medical outcome-based curricula. Its functionalities and outputs were verified by pilot mapping of Anatomy curricula as taught at partner universities in five European countries. Conclusions The visualisation and the analysis of described curriculum data using natural language processing techniques revealed both the hidden relations between curriculum building blocks and a set of overlaps and gaps in curricula. In addition, we demonstrate both the usability of the platform in the context of the involved academic environments and the capability to map and compare curricula across different institutions and different countries.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44713119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Radioactive nuclei for β+γ PET and theranostics: selected candidates β+γ PET的放射性核和治疗:选定的候选物

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-16 DOI: 10.1515/bams-2021-0142

T. Matulewicz

引用次数: 9

Prospects for the production of radioisotopes and radiobioconjugates for theranostics 用于治疗的放射性同位素和放射性生物偶联物的生产前景

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-16 DOI: 10.1515/bams-2021-0136

J. Choiński, M. Lyczko

引用次数: 10

History of positron emission tomography (PET) in Poland 波兰正电子发射断层扫描（PET）的历史

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-11-08 DOI: 10.1515/bams-2021-0145

P. Cegła, T. Piotrowski

引用次数: 1

An economic approach to energy budgets: HOW many resources should living organisms spare? 能源预算的经济方法:生物体应该节省多少资源?

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-10-15 DOI: 10.20944/preprints202110.0234.v1

Arturo Tozzi

{"title":"An economic approach to energy budgets: HOW many resources should living organisms spare?","authors":"Arturo Tozzi","doi":"10.20944/preprints202110.0234.v1","DOIUrl":"https://doi.org/10.20944/preprints202110.0234.v1","url":null,"abstract":"Ramsey's economic theory of saving (RTS) estimates how much of its commodities a nation should save to safeguard the well-being of future generations. Since RTS retains many attractive qualities such as simplicity, strength, breadth and generality, here we ask if it would be useful to investigate biophysical issues. Specifically, we focus on a biological topic that lends itself as a backdrop for the study of the imbalance between intake and expenditure, i.e., the evaluation of the multicellular living organisms' energetic requirements and constraints. Our problem is to find at each time the optimum distribution and the right balance of the cellular energy budget between consumption and storage: how much must a living organism spare to increase its chances of survival over long periods? To give an operational example, we discuss the ATP requirements in the central nervous system during the spontaneous and the evoked activity of the brain, showing that the experimentally detected values of energetic expenditure during neural computations match well with the estimations provided by RTS. Suggesting how to find the optimum allocation of the available energy between expenditure and saving at each time, RTS approaches to biological energy budgets may have a wide range of experimental applications, such as: a) optimization of the long-term survival chances of either immortalized cell cultures, or beneficial bacterial colonies and exogenous probiotic mixtures; b) eradication of detrimental biofilms, such as, e.g., heart valves' Streptococcus colonies; c) novel anti-stress and anti-ageing strategies.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90237625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Image processing algorithms in the assessment of grain damage degree 图像处理算法在晶粒损伤程度评估中的应用

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-10-12 DOI: 10.1515/bams-2021-0063

Wojciech Maliga, W. Dudziński, M. Łabowska, J. Detyna, Marcin Łopusiewicz, H. Bujak

{"title":"Image processing algorithms in the assessment of grain damage degree","authors":"Wojciech Maliga, W. Dudziński, M. Łabowska, J. Detyna, Marcin Łopusiewicz, H. Bujak","doi":"10.1515/bams-2021-0063","DOIUrl":"https://doi.org/10.1515/bams-2021-0063","url":null,"abstract":"Abstract Objectives The paper presents preliminary results on the assessment of algorithms used in image processing of the grain damage degree. The purpose of the work is developing a tool allowing to analyse sample cross-sections of rye germs. Methods The analysis of the grain cross-sections was carried out on the basis of a series their photos taken at equal time intervals at a set depth. The cross-sections will be used to create additional virtual cross-sections allowing to analyse the whole sample volume. The ultimate plan is to generate two cross-sections perpendicular to each other. Based on volumetric data read from the sample section, a three-dimensional model of an object will be generated. Results The analysis of model surface will allowed us to detect possible grain damage. The developed method of preparing the research material and the proprietary application allowed for the identification of internal defects in the biological material (cereal grains). Conclusions The presented methodology may be used in the agri-food industry in the future. However, much research remains to be done. These works should primarily aim at significantly reducing the time-consuming nature of individual stages, as well as improving the quality of the reconstructed image.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48651390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ovarian cancer diagnosis using pretrained mask CNN-based segmentation with VGG-19 architecture 基于VGG-19架构的预训练掩模cnn分割卵巢癌诊断

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2021-09-29 DOI: 10.1515/bams-2021-0098

K. Senthil, Vidyaathulasiraman

引用次数: 2