Radioactive nuclei for β+γ PET and theranostics: selected candidates

IF 1.2 Q3 Computer Science

Bio-Algorithms and Med-Systems Pub Date : 2021-11-16 DOI:10.1515/bams-2021-0142

T. Matulewicz

引用次数: 9

Abstract

Abstract Positron emission tomography (PET) is an established medical diagnostic imaging method. Continuous improvements are aimed at refining image reconstruction, reducing the amount of radioactive tracer and combining with targeted therapy. Time-of-flight (TOF)-PET provides the localization of the tracer through improved time resolution, nuclear physics may contribute to this goal via selection of radioactive nuclei emitting additional γ-rays. This additional radiation, when properly detected, localizes the decay of the tracer at the line of response (LoR) determined by two detected 511 keV quanta. Selected candidates are presented. Some are particularly interesting, as they are strong candidates for theranostic applications.

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β+γ PET的放射性核和治疗:选定的候选物

摘要正电子发射断层扫描(PET)是一种成熟的医学诊断成像方法。持续的改进旨在改善图像重建，减少放射性示踪剂的量，并结合靶向治疗。飞行时间(TOF)-PET通过提高时间分辨率来定位示踪剂，核物理学可以通过选择放射额外γ射线的放射性核来实现这一目标。这种额外的辐射，当适当检测到，将示踪剂的衰减定位在响应线(LoR)上，该响应线由两个检测到的511kev量子确定。介绍选定的候选人。其中一些特别有趣，因为它们是治疗应用的有力候选者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bio-Algorithms and Med-Systems MATHEMATICAL & COMPUTATIONAL BIOLOGY-

CiteScore

3.80

自引率

0.00%

发文量

期刊介绍： The journal Bio-Algorithms and Med-Systems (BAMS), edited by the Jagiellonian University Medical College, provides a forum for the exchange of information in the interdisciplinary fields of computational methods applied in medicine, presenting new algorithms and databases that allows the progress in collaborations between medicine, informatics, physics, and biochemistry. Projects linking specialists representing these disciplines are welcome to be published in this Journal. Articles in BAMS are published in English. Topics Bioinformatics Systems biology Telemedicine E-Learning in Medicine Patient''s electronic record Image processing Medical databases.