Bio-Algorithms and Med-Systems最新文献

Propagation of electrical signals by fungi 真菌的电信号传播

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2023-04-20 DOI: 10.48550/arXiv.2304.10675

Richard Mayne, Nic Roberts, Neil Phillips, Roshan Weerasekera, A. Adamatzky

引用次数: 2

Light induced spiking of proteinoids 光诱导的类蛋白刺突

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2023-03-30 DOI: 10.48550/arXiv.2303.17563

Panagiotis Mougkogiannis, A. Adamatzky

引用次数: 2

Transfer Functions of Proteinoid Microspheres 类蛋白微球的传递函数

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2023-02-09 DOI: 10.48550/arXiv.2302.05255

Panagiotis Mougkogiannis, Neil Phillips, A. Adamatzky

{"title":"Transfer Functions of Proteinoid Microspheres","authors":"Panagiotis Mougkogiannis, Neil Phillips, A. Adamatzky","doi":"10.48550/arXiv.2302.05255","DOIUrl":"https://doi.org/10.48550/arXiv.2302.05255","url":null,"abstract":"Proteinoids, or thermal proteins, are inorganic entities formed by heating amino acids to their melting point and commencing polymerisation to form polymeric chains. Typically, their diameters range from 1μm to 10μm. Some amino acids incorporated into proteinoid chains are more hydrophobic than others, leading proteinoids to cluster together when they are present in aqueous solutions at specific concentrations, allowing them to grow into microspheres. The peculiar structure of proteinoids composed of linked amino acids endows them with unique properties, including action-potential like spiking of electrical potential. These unique properties make ensembles of proteinoid microspheres a promising substrate for designing future artificial brains and unconventional computing devices. To evaluate a potential of proteinoid microspheres for unconventional electronic devices we measure and analyse the data-transfer capacities of proteinoid microspheres. In experimental laboratory conditions we demonstrate that the transfer function of proteinoids microspheres is a nontrivial phenomenon, which might be due to the wide range of proteinoid shapes, sizes, and structures.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83377819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Application of quantum entanglement induced polarization for dual-positron and prompt gamma imaging. 量子纠缠诱导偏振在双正电子和瞬时伽马成像中的应用。

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2023-01-01 Epub Date: 2023-12-30 DOI: 10.5604/01.3001.0054.1817

Gregory Romanchek, Greyson Shoop, Shiva Abbaszadeh

{"title":"Application of quantum entanglement induced polarization for dual-positron and prompt gamma imaging.","authors":"Gregory Romanchek, Greyson Shoop, Shiva Abbaszadeh","doi":"10.5604/01.3001.0054.1817","DOIUrl":"10.5604/01.3001.0054.1817","url":null,"abstract":"<p><p>The intrinsic resolution of Positron Emission Tomography (PET) imaging is bound by positron range effects, wherein the radioactive decay of the imaging tracer occurs at a disjoint location from positron annihilation. Compounding this issue are the variable ranges positrons achieve, depending on tracer species (the energy they are emitted with) and the medium they travel in (bone vs soft tissue, for example) - causing the range to span more than an order of magnitude across various study scenarios (~0.19 mm to ~6.4 mm). Radioisotopes, such as Zr-89, exhibit dual emissions of positron and prompt gammas, offering an opportunity for accurate tracer positioning as prompt gammas originate from the tracer location. These multi-emission radiotracers have historically suffered from increased noise corresponding to the third gamma interfering in annihilation gamma coincidence pairing. Recent advancements, however, have brought to light the unique property of annihilation gammas having scattering kinematics distinct from random gamma pairs. These properties are born from the singular quantum entanglement state available to the gamma pair following para-positronium decay which prescribes linearly orthogonal polarization. Such coherent polarization is not shared by prompt gamma emissions, offering an opportunity for their discrimination. We present an investigation into this technique, comparing the distribution of relevant scattering kinematics of entangled annihilation gammas and corresponding prompt gammas via a Monte Carlo simulation.</p>","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11288065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility study of positronium application for blood clots structural characteristics 正电子素应用于血栓结构特征的可行性研究

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2022-12-01 DOI: 10.2478/bioal-2022-0087

S. Moyo, P. Moskal, E. Stępień

引用次数: 1

Multi-molecule imaging and inter-molecular imaging in nuclear medicine 核医学中的多分子成像和分子间成像

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2022-12-01 DOI: 10.2478/bioal-2022-0081

K. Shimazoe, M. Uenomachi

引用次数: 2

A new brain dedicated PET scanner with 4D detector information 一种新的大脑专用PET扫描仪，具有4D检测器信息

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2022-12-01 DOI: 10.2478/bioal-2022-0083

A. Gonzalez-Montoro, J. Barberá, D. Sanchez, Alvaro Mondejar, M. Freire, Karel Diaz, Alejandro Lucero, S. Jiménez-Serrano, J. Alamo, C. Morera-Ballester, J. Barrio, N. Cucarella, V. Ilisie, L. Moliner, C. Valladares, Antonio J. Gonzalez, John O. Prior, J. Benlloch

{"title":"A new brain dedicated PET scanner with 4D detector information","authors":"A. Gonzalez-Montoro, J. Barberá, D. Sanchez, Alvaro Mondejar, M. Freire, Karel Diaz, Alejandro Lucero, S. Jiménez-Serrano, J. Alamo, C. Morera-Ballester, J. Barrio, N. Cucarella, V. Ilisie, L. Moliner, C. Valladares, Antonio J. Gonzalez, John O. Prior, J. Benlloch","doi":"10.2478/bioal-2022-0083","DOIUrl":"https://doi.org/10.2478/bioal-2022-0083","url":null,"abstract":"\u0000 In this article, we present the geometrical design and preliminary results of a high sensitivity organ-specific Positron Emission Tomography (PET) system dedicated to the study of the human brain. The system, called 4D-PET, will allow accurate imaging of brain studies due to its expected high sensitivity, high 3D spatial resolution and, by including precise photon time of flight (TOF) information, a boosted signal-to-noise ratio (SNR).\u0000 The 4D-PET system incorporates an innovative detector design based on crystal slabs (semi-monolithic) that enables accurate 3D photon impact positioning (including photon Depth of Interaction (DOI) measurement), while providing a precise determination of the photon arrival time to the detector. The detector includes a novel readout system that reduces the number of detector signals in a ratio of 4:1 thus, alleviating complexity and cost. The analog output signals are fed to the TOFPET2 ASIC (PETsys) for scalability purposes.\u0000 The present manuscript reports the evaluation of the 4D-PET detector, achieving best values 3D resolution values of <1.6 mm (pixelated axis), 2.7±0.5 mm (monolithic axis) and 3.4±1.1 (DOI axis) mm; 359 ± 7 ps coincidence time resolution (CTR); 10.2±1.5 % energy resolution; and sensitivity of 16.2% at the center of the scanner (simulated). Moreover, a comprehensive description of the 4D-PET architecture (that includes 320 detectors), some pictures of its mechanical assembly, and simulations on the expected image quality are provided.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48429535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Comparison of qNANO results from the isolation of extracellular microvesicles with the theoretical model 细胞外微泡分离的qNANO结果与理论模型的比较

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2022-12-01 DOI: 10.2478/bioal-2022-0088

M. Durak-Kozica, Andrzej Wróbel, M. Platt, E. Stępień

引用次数: 1

A double photon coincidence detection method for medical gamma-ray imaging 一种用于医学伽马射线成像的双光子符合检测方法

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2022-12-01 DOI: 10.2478/bioal-2022-0080

M. Uenomachi, K. Shimazoe, H. Takahashi

引用次数: 2

Multi-photon time-of-flight MLEM application for the positronium imaging in J-PET 多光子飞行时间MLEM在J-PET正电子成像中的应用

IF 1.2

Bio-Algorithms and Med-Systems Pub Date : 2022-12-01 DOI: 10.2478/bioal-2022-0082

R. Shopa, K. Dulski

{"title":"Multi-photon time-of-flight MLEM application for the positronium imaging in J-PET","authors":"R. Shopa, K. Dulski","doi":"10.2478/bioal-2022-0082","DOIUrl":"https://doi.org/10.2478/bioal-2022-0082","url":null,"abstract":"\u0000 We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences comprising two annihilation and one de-excitation photons that originate from the ortho-positronium (o-Ps) decay. Using the Geant4 library, a Monte Carlo simulation was conducted for four cylindrical 22Na sources of β+ decay with diverse o-Ps mean lifetimes, placed symmetrically inside the two JPET prototypes. The estimated time differences between the annihilation and the positron emission were aggregated into histograms (one per voxel), updated by the weights of the activities reconstructed by TOF MLEM. The simulations were restricted to include only the o-Ps decays into back-to-back photons, allowing a linear fitting model to be employed for the estimation of the mean lifetime from each histogram built in the log scale. To suppress the noise, the exclusion of voxels with activity below 2% – 10% of the peak was studied. The estimated o-Ps mean lifetimes were consistent with the simulation and distributed quasi -uniformly at high MLEM iterations. The proposed positronium imaging technique can be further upgraded to include various correction factors, as well as be modified according to realistic o-Ps decay models.","PeriodicalId":42620,"journal":{"name":"Bio-Algorithms and Med-Systems","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46202212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3