African Journal of Neurological Sciences最新文献

{"title":"10.4314/ajns.v9i2.70404","authors":"","doi":"10.4314/ajns.v9i2.70404","DOIUrl":"https://doi.org/10.4314/ajns.v9i2.70404","url":null,"abstract":"","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2020-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajns.v9i2.70404","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47344091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"10.4314/ajns.v9i2.70406","authors":"","doi":"10.4314/ajns.v9i2.70406","DOIUrl":"https://doi.org/10.4314/ajns.v9i2.70406","url":null,"abstract":"Introduction La craniectomie decompressive peut- elle ameliorer le pronostic des patients victimes d’un traumatisme crânien ferme grave avec engagement cerebral ? Objectif Le but de la presente etude etait d’evaluer l’efficacite de la craniectomie decompressive dans la prise en charge du traumatisme crânien grave, isole et ferme avec signes radiologiques d’engagement cerebral. Methodes Il s’agissait d’une etude realisee a l’Hopital General de Douala pendant 36 mois, de janvier 2007 a decembre 2009, incluant 13 patients victimes d’un traumatisme crânien grave, isole et ferme, presentant les signes radiologiques d’engagement cerebral. La craniectomie decompressive etait indiquee devant l’aggravation ou la persistance du tableau clinique et radiologique malgre le traitement medical conventionnel. Resultats Apres deux a dix mois de suivi, l’evolution fut classee selon le score du coma evolutif ; \"Glasgow outcome scale (GOS) score \". Dix patients (76, 93 %) ont evolue favorablement GOS (4-5).Un patient (07,69%) est reste vegetatif GOS3. Deux deces (15,38%) ont ete observe GOS1. Les principales complications etaient : une hydrocephalie, une hernie cerebrale a travers le foramen de craniectomie, un abces du cerveau et un etat de mal convulsif. Conclusion La craniectomie decompressive est une methode efficace pouvant ameliorer le pronostic des patients victimes de traumatisme crânien grave avec signes radiologiques d’engagement cerebral. Mots cles : craniectomie-decompressive-engagement cerebral-traumatisme crânien.","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2020-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajns.v9i2.70406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48535469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enquete sur la prevalence de la migraine chez l’adulte a titirou au Nord du Benin en 2017","authors":"T. Adoukonou, M. Agbétou, Gottfried Agballa, Aude Charles Gahou, Donald Accrombessi, O. Kossi, D. Houinato","doi":"10.4314/AJNS.V37I2","DOIUrl":"https://doi.org/10.4314/AJNS.V37I2","url":null,"abstract":"Introduction : La migraine est une maladie neurologique frequente en population, source de handicap et classee 13eme des affections les plus handicapantes par l’OMS. L’objectif de cette etude etait d’etudier la prevalence de la migraine a Titirou en 2017. Methodes : Il s’est agi d’une etude transversale de type porte-a-porte menee sur 2065 sujets âges de 18 a 65 ans. L’enquete a ete effectuee sur une periode de 4 mois allant du 10 avril au 05 aout 2017. Les criteres diagnostiques de l’International Headache Society (IHS) de 2013 ont servi de base pour le diagnostic de la migraine. Les informations sociodemographiques, le poids et taille et les donnees relatives a la frequence et l’intensite des cephalees furent collectes. Les donnees ont ete saisies, traitees et analysees grâce au logiciel Epi Info version 2.2.0.165. Resultats : Il y avait une predominance masculine avec un sex-ratio de 1,41. Les sujets etaient âges de 18 a 65 ans avec une moyenne d’âge de 31,87±8,37ans. La prevalence des cephalees etait de 63,49%. La  prevalence de la migraine a Titirou etait de 3,82% [IC95% : (3,06%-4,72%)] (79 sur les 2065). Les facteurs associes a la migraine etaient l’âge (p=0,0026), le sexe (p=0,0001), le niveau d’instruction (p=0,0039), la profession (p<10-4 ) et l’indice de masse corporelle (p<10-4 ). L’intensite des cephalees etait moderee dans 44,30%, forte dans 51,90%,  extremement forte chez 3,80% des sujets. La plupart des migraineux  (78,48%), avait moins de 5 crises par mois. La migraine avec aura  representait 49,4%. Les auras les plus observees etaient les phosphenes (34,18%), les scotomes (13,92%) et l’aura sensitive (13,92%). Les  facteurs declenchant les acces etaient le manque de sommeil (84,81%), la contrariete (68,35%) et le souci (62,03%). Conclusion : La migraine est assez frequente et sa prevalence est comparable a celle rapportee dans la plupart des etudes en communaute en Afrique. Mots cles : Migraine -Prevalence-Adulte-Benin Introduction : The migraine is a common neurological disorder with a serious handicap and classified as the 13th disabling disease worldwide. The most consistently data on epidemiology of migraine are available in general population in Africa but not in northern Benin. We aimed to study the prevalence of migraine at Titirou in Parakou in 2017. Methods : This was a cross-sectional with door-to-door survey which included 2065 subjects aged 18 to 65 years. The survey was conducted over a period of 4 months from 10 April to 05 August 2017. The IHS diagnostic criteria of 2013 were used to define migraine. Socio-demographics information was collected. The data were analyzed using Epi Info 2.2.0.165.fr software. Results : There was a male predominance with 58.45% of men with sex ratio of 1.41. The mean age was 31.87 ± 8.37 years. The prevalence of headache was 63.49%. The prevalence of migraine in Titirou was 3.82% [95%CI: 3.06%-4.72%]. The associated factors were the age (p=0.00), the sex (p=0.00), level of education (p","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"37 1","pages":"42-50"},"PeriodicalIF":0.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/AJNS.V37I2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation de la charge de l’aidant apres un accident vasculaire cerebral au Centre Hospitalier Universitaire de Brazzaville","authors":"G. Mpandzou, Amour Ngouma, P. Ossou-Nguiet, Aubaine Nkounkou, Dinah Happhia Motoula Latou, Eliot Prince Sounga Bandzouzi, Ngandzali Davelle Doungou, B. Bandzouzi-Ndamba, R. Bileckot","doi":"10.4314/AJNS.V37I1","DOIUrl":"https://doi.org/10.4314/AJNS.V37I1","url":null,"abstract":"Introduction: L’accident vasculaire cerebral (AVC) est la premiere cause du handicap acquis de l’adulte et la deuxieme cause de demence. Le retour au domicile du patient est etroitement lie a la charge de l’aidant. Le but de notre etude etait d’evaluer la charge de l’aidant principal des patients victimes d’AVC apres le retour au domicile. Methode: Il s’est agi d’une etude longitudinale analytique realisee du 1er octobre 2014 au 30 septembre 2015, au CHU de Brazzaville. Tous les patients hospitalises pour un premier AVC confirme par une imagerie cerebrale et retournes a leur domicile ont ete inclus. Tous les patients ayant un score de Rankin modifie ≥ 2 avant l’hospitalisation n’ont pas ete inclus. L’echelle de Zarit a ete utilisee pour evaluer la charge de l’aidant principal. Les autres variables etudiees regroupaient les donnees sociodemographiques des patients et des aidants. L’impact psychologique et fonctionnel de l’hemiplegie vasculaire des patients, a ete evalue respectivement par le questionnaire abrege de Beck et l’index de Barthel. Le logiciel SPSS 21 a ete utilise pour l’analyse statistique. Le seuil de significativite a ete fixe a 0,05. Resultats: L’etude a porte sur 70 patients d’âge moyen de 55,4±11,49 ans, avec un sex ratio de 1,12. L’aidant principal etait represente par un descendant dans 44,5%. L’âge moyen des aidants etait de 41,4 ± 11,9 ans, significativement inferieur a celui des patients (p < 0,001). Le score de Zarit moyen etait de 44,8 ±10,6 ; 36,4 ±12,1 et 27,2 ±13,8 respectivement a un, trois et six mois de suivi. La charge de l’aidant s’est amelioree avec le temps, avec une variation moyenne du score de Zarit entre le premier et sixieme mois de suivi statistiquement significative de -17,6±8,16 (p<0,001). L’âge du patient « superieur a 65 ans », le mode de vie « avec conjoint » et le type d’AVC « hemorragique » etaient identifies comme facteurs associes a la charge de l’aidant. Conclusion: La charge de l’aidant principal s’ameliore au cours de l’evolution, avec l’amelioration de l’autonomie fonctionnelle et de l’humeur des patients. Il est necessaire d’inclure cette donnee lors de l’education therapeutique des aidants dans le cadre d’une prise en charge globale des AVC. Mots cles: Accident vasculaire cerebral, Congo, Charge aidant, invalidite, readaptation English Title:  Assessment of caregiver’s burden after stroke at the Brazzaville University Hospital English Abstract Introduction: Stroke is the leading cause of acquired disability in adults and the second leading cause of dementia. After the hospitalization phase, the return to the patient’s home is closely linked to the caregiver’s burden. The aim of our study was to assess the burden of the primary caregiver of stroke patients after returning home. Method: This was a longitudinal study carried out from 1st October 2014 to 30th September 2015 at the university hospital of Brazzaville. All patients hospitalized for a first stroke confirmed by brain imaging and retur","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"37 1","pages":"3-11"},"PeriodicalIF":0.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiochirurgie des malformations arterio-veineuses du tronc cerebral stereotactic radiosurgery for brainstem arteriovenous malformations","authors":"M. Faye, Pierre Yves Borius, Marc Guichard Tsiaremby, M. Diallo, Jean-Marie Regis","doi":"10.4314/AJNS.V36I2","DOIUrl":"https://doi.org/10.4314/AJNS.V36I2","url":null,"abstract":"Introduction: Les malformations arterio-veineuses ou angiomes cerebraux sont des anomalies vasculaires congenitales qui se definissent par la presence d’un shunt arterio-veineux anormal. Materiels et methodes: Nous avons mene une etude retrospective entre Janvier 1992 et Decembre 2010 au service de radiochirurgie de l’hopital de la Timone, 1557 patients ont ete traites par radiochirurgie pour une malformation arterioveineuse dont 61 patients pour une localisation du tronc cerebral (3.91%). Resultats: L’âge moyen de 35.8-/+16.6 ans (4-75).16 patients avaient beneficie d’une embolisation preradiochirurgicale (26.23%). Le mode de decouverte etait une hemorragie pour 53 patients (87%). Le volume moyen de traitement etait de 1.43+/-1.96 cm 3 (0.09-14.20). Le score RBAS etait en moyenne de 1.36 +/- 0.34 (0.64-2.35). La dose moyenne de prescription a l’enveloppe l’isodose 50% delivree etait de 22.9 +/-2.9 Gy (12-30), la dose mediane etait de 24 Gy).Notre taux d’obliteration global apres une ou deux procedures etait de 67.27%, pour un delai moyen de suivi est de 56.7 mois+/-43.3 (8.1-251.7). Les facteurs en rapport avec une obliteration) : score RBAS bas (p=0.012), une dose de traitement superieur a 20Gy (p=0.034). Nous avons eu une mortalite de 1.63% et un pourcentage de saignement apres la procedure de 6.55% et 3.2% deficits neurologiques radio-induits. Conclusion: La radiochirurgie est maintenant devenue incontournable dans le traitement des malformations du tronc cerebral meme s’il existe un risque hemorragique persistant jusqu’a la guerison (3.5%). Le taux d’obliteration complete est de 67.27% Mots cles: malformations arterio-veineuses, tronc cerebral, radiochirurugie English Title:  Stereotactic radiosurgery for brainstem arteriovenous malformations English Abstract Introduction: Arterioveinous malformations (AVM) or cerebral angiomas are congenital vascular abnormalities which are defined by the presence of abnormal arterio-veinous shunt. Methods:  We lead a retrospective study recruiting 1557 patients treated between January 1992 and December 2010 in the Radiosurgery Unit of La Timone hospital in Marseille. All patients received radiosurgery for management of an AVM, 61 of them being brainstem AVMs (3.91%). Results: Mean age was 35.8 +/- 16.6 years. Sixteen patients underwent arterial embolization before surgery (26.23%). Hemorrhage was the primary onset for 53 patients (87%). Mean volume before treatment was 1.43+/-1.96 cm 3 (0.09-14.20). Average RBAS score was 1.36 +/-0.34 (0.64-2.35). Average prescripted dose for 50% delivered iso-dose was 22.9 +/-2.9 Gy (12-30), mean dose was 24 Gy. Our global occlusion rate after one or two treatments was 67.27%, considering an average follow-up of 56.7 months +/- 43.3 (8.1- 251.7). Occlusion related factors were: low RBAS score (p=0.012), received dose higher than 20Gy (p=0.034). Our death rate was 1.63% and our post-procedure bleeding rate was 6.55% with 3.2% of neurological post-procedure deficience. Conc","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"36 1","pages":"3-12"},"PeriodicalIF":0.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREVALENCE OF EPILEPSY IN A BRAZILIAN SEMIURBAN REGION: AN EPIDEMIOLOGICAL STUDY","authors":"Pascal M’Belesso, Angélique Faure-Delage, M. Guerchet, B. Bandzouzi-Ndamba, A. Mouanga, A. Tabo, L. Cartz-Piver, P. Preux, J. Clément, P. Nubukpo","doi":"10.4314/ajns.v35i1","DOIUrl":"https://doi.org/10.4314/ajns.v35i1","url":null,"abstract":"Objective: WHO estimates 8/1000 individuals worldwide suffer from epilepsy, and prevalence in developing countries is usually higher than that in developed countries. According to United Nations Program for Development in Human Development Report 2013, Brazil ranks 85 th in Human Development Index with a course of “high performance” in human development over the past decades. Adequate sanitary conditions indirectly indicate higher educational and health levels. This study aimed to describe the prevalence of epilepsy in the Brazilian semiurban region of Mato Grosso. Methods: A door-to-door survey was conducted in a semiurban area of Barra do Bugres in 2011. In phase 1, health agents screened participants with the Limoges questionnaire, which is a validated method used to identify patients with epilepsy in tropical regions, and in phase 2, neurological evaluation was performed on detected cases. Results: Of the 30,132 subjects who were screened, 305 were deemed positive and were advanced to phase 2 evaluation. Epilepsy was diagnosed in 241 subjects (76 children and 165 adults). The prevalence of epilepsy was 7.8/1000 inhabitants, and the overall prevalence rate of active epilepsy was 5.6/1000 inhabitants. In this study, 55.9% were male, afro-descendant ethnicity was reported by 68.7% subjects, 24.4% were declared as illiterate, and 95.5% had toilets inside their house. Conclusion: The present study is the first conducted in a semiurban region of Brazil using a population survey to evaluate epilepsy prevalence rates. These findings suggested that the association between improvements in health conditions and education are important factors for low epilepsy prevalence rates.","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"108 1","pages":"14-25"},"PeriodicalIF":0.1,"publicationDate":"2016-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cavernome intramedullaire: a propos d’un cas","authors":"T. Ngamasata, A. Bertal, M. Dianka, S. Hilmani, K. Ibahiouin, A. Lakhdar, A. Naja, M. Karkouri, A. E. Azahri","doi":"10.4314/AJNS.V34I1","DOIUrl":"https://doi.org/10.4314/AJNS.V34I1","url":null,"abstract":"Le cavernome intramedullaire, malformation vasculaire rare, represente environ 5 a 12 % des malformations vasculaires spinales et 3 % des malformations vasculaires intra-durales. Il peut etre longtemps asymptomatique ou se manifester par une alteration brutale ou progressive des fonctions medullaires. Le diagnostic repose sur l’imagerie par resonance magnetique (IRM) medullaire et l’anatomopathologie. La chirurgie represente l’essentiel de la prise en charge, neanmoins elle n’est pas denudee de complications. Nous rapportons un cas de cavernome intramedullaire chez une patiente de 24 ans, admise dans un tableau de compression medullaire dorsale lente avec une paraparesie evoluant depuis 2 ans. L’IRM medullaire a objective une lesion intramedullaire en regard deT7-T8. La patiente a beneficie d’une exerese totale de la tumeur et l’histologie a confirme le cavernome intramedullaire. L’evolution a ete marquee par une aggravation partielle du deficit moteur. A travers cette observation, les auteurs discutent les aspects cliniques, radiologiques ainsi que la prise en charge de cette pathologie rare. Mots cles: Cavernome, intramedullaire, malformation vasculaire","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"34 1","pages":"48-53"},"PeriodicalIF":0.1,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/AJNS.V34I1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Description d’un cas de la maladie de Marchiafava-Bignami dans le service de neurologie- Chu de Cocody a Abidjan","authors":"Diarra Evelyne Aka-Anghui, Mamadou Zakaria, C. Tanoh, Y. F. Boa, A. Kouamé-Assouan, B. Assi","doi":"10.4314/ajns.v34i2","DOIUrl":"https://doi.org/10.4314/ajns.v34i2","url":null,"abstract":"Introduction Complication rare de l’intoxication ethylique, la maladie de Marchiafava-Bignami est caracterisee par une atteinte demyelinisante et une necrose de la partie mediane du corps calleux. Observation Nous rapportons l’observation d’un patient de 48 ans, ethylique chronique, qui a consulte pour des troubles mnesiques d’installation progressive. Un syndrome  dementiel chronique associe a un syndrome pyramidal diffus et un syndrome de deconnexion inter hemispherique ont ete objectives. Le diagnostic a ete confirme par l’imagerie par resonance magnetique (l’IRM) crânio encephalique. L’analyse du Liquide cerebrospinal etait normale. Discussion Le tableau clinique de cette affection est aspecifique. Nous insistons sur la mise en evidence d’un terrain d’ethylisme chronique et la contribution de l’IRM cerebrale qui reste le principal outil diagnostique. Conclusion L’ethylisme chronique expose au risque de survenue de complications neurologiques graves dont la maladie de Marchiafava-Bignami.","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"58 1","pages":"64-68"},"PeriodicalIF":0.1,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gross motor function classification system family questionnaire: validating Yoruba-Nigerian version","authors":"M. Fatudimu, Tal-hatu Kolapo Hamzat, A. Oyeyemi","doi":"10.4314/AJNS.V33I1","DOIUrl":"https://doi.org/10.4314/AJNS.V33I1","url":null,"abstract":"Background  Assessment of the functional abilities of children with cerebral palsy would be more reliable if care givers are included. An instrument commonly used for assessing functional abilities in CP by their caregivers is the Gross Motor Function Classification System Family Questionnaire. No Nigerian Version of this instrument is currently available; hence this study was designed to evaluate the criterion- related validity of the Yoruba (Nigerian) version of the GMFCSFQ among care givers of children with cerebral palsy. Method  Fifteen primary caregivers of children with CP, who are fluent in speaking, reading, and writing both English and Yoruba Languages, were purposively sampled from among those bringing their children or wards for physiotherapy at the University College Hospital Nigeria and involved in this study. The participants completed within one week interval, the English and Yoruba versions of the GMFCSFQ by choosing one of the five ordinal levels corresponding to the gross motor function of their children. Spearman’s correlation coefficient was used to examine the relationship between the scores from the English and the Yoruba versions of the instrument. Significant level was set at ά=0.05. Results  A strong positive and significant correlation was obtained between the English and Yoruba Versions of the GFMCSFQ (ρ=0.89, p=0.00). Conclusion  This suggests that the Yoruba version of the GMFCSFQ is a valid version of the original (English) version. It could therefore be used to gather information about the gross motor function of children with cerebral palsy from their family members or caregivers among Yoruba speaking people of West Africa and in Diaspora. Key words: Cerebral Palsy, Gross Motor Function, Yoruba.","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"33 1","pages":"30-34"},"PeriodicalIF":0.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/AJNS.V33I1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accident vasculaire cerebral ischemique post-chimiotherapie pour cancer du sein","authors":"C. Akosile, B. Adegoke, C. Ezeife, F. Maruf, P. Ibikunle, O. Johnson, C. Ihudiebube-Spendor, O. Dada","doi":"10.4314/ajns.v32i1","DOIUrl":"https://doi.org/10.4314/ajns.v32i1","url":null,"abstract":"Introduction La chimiotherapie anticancereuse est pourvoyeuse d’un large spectre de complications neurologiques. Parmi ces complications les accidents vasculaires cerebraux ischemiques (AVCI) restent un evenement inhabituel dont l’incidence est de 0,14%. Objectif Rapporter et commenter l’observation d’une patiente ayant presente un AVCI dans les suites d’une chimiotherapie pour cancer du sein. Observation Patiente âgee de 46ans, traitee pour une epilepsie generalisee, et sans facteur de risque cardiovasculaire, est suivie pour un cancer du sein. Elle a presente au decours de la chimiotherapie un accident vasculaire cerebral ischemique sylvien droit confirme au scanner cerebral. Les explorations cardiaques sont normales, ainsi que le bilan biologique etiologique. Discussion Le diagnostic d’AVC post-chimiotherapie a ete retenu chez notre patiente sur la base de l’absence de facteur de risque vasculaire et la negativite du bilan etiologique, ainsi que l’usage du 5 Fluorouracile qui a ete incrimine dans la survenue d’AVC ischemiques. La survenue de cette complication depend du type de drogue utilise, et de certaines associations therapeutiques, et releverait de plusieurs mecanismes pouvant etre intriques. Le bilan doit etre le plus complet possible afin d’affirmer l’imputabilite de la chimiotherapie. Conclusion Notre observation souligne la severite des complications neurologiques de la chimiotherapie, ainsi que le dilemme therapeutique pose, en l’absence de protocole de prise en charge codifie. Mots cles : Accident vasculaire cerebral, cancer du sein, chimiotherapie, toxicite, 5-Fluorouracile","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"32 1","pages":"26-32"},"PeriodicalIF":0.1,"publicationDate":"2013-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}