Y. Sakho, F. Holden, N. Ndoye, M. Ba, Diene, S. Badiane, J. Dangou, F. Diouf, K. Dia, C. Seck
{"title":"Chirurgie Des Méningiomes Intracrâniens Dans Une Unité Neurochirurgicale De Dakar","authors":"Y. Sakho, F. Holden, N. Ndoye, M. Ba, Diene, S. Badiane, J. Dangou, F. Diouf, K. Dia, C. Seck","doi":"10.4314/AJNS.V24I1.7562","DOIUrl":"https://doi.org/10.4314/AJNS.V24I1.7562","url":null,"abstract":"Objectifs \u0000Rapporter notre experience sur la chirurgie des meningiomes intracrâniens a Dakar .\u0000\u0000Methode \u0000Les auteurs rapportent une serie retrospective de 24 patients porteurs de meningiomes intracrâniens operes dans une unite neurochirurgicale differente de notre institution mere a Dakar . Le recrutement s'est fait de Janvier 2001 a Juillet 2004. L'evaluation diagnostique a repose essentiellement sur la tomodensitometrie cerebrale et l'anatomo-pathologie.\u0000\u0000Resultats \u0000Il s'agissait de 17 femmes et de 7 hommes. L'âge de nos patients variaient entre 21 et 77 ans avec un pic de frequence a 55 ans . Le syndrome d'hypertension intracrânienne et la comitialite ont ete les circonstances diagnostiques les plus frequentes avec un taux de 37%. La tomodensitometrie cerebrale a permis d'evoquer un diagnostic presomptif de nature. Concernant la topographie, les meningiomes de la convexite ont ete observes dans 50% des cas suivis par les meningiomes de la base (20%). L'evaluation de la qualite de l'exerese chirurgicale selon le grading de Simpson a retrouve 20% de grade I et 64% de grade II. L'insuffisance du plateau technique et le manque de competences en neuroanesthesie rendent compte de la mortalite post-operatoire de 12%.\u0000\u0000Conclusion \u0000Ce travail nous permet de proposer une strategie d'amelioration de la pratique neurochirurgicale tumorale en Afrique subsaharienne.\u0000\u0000 Objective \u0000To report our experience of intracranial meningiomas surgery in Dakar.\u0000\u0000Method We analysed a population of 24 patients who underwent operation in a Neurosurgical unit different from our mother Institution. Brain CT scan has been done for every patient and histopathological confirmation has been reached for all patients.\u0000\u0000Results \u0000Regarding sex, we have 17 females for 7 males. The patient age was between 21 and 77 years old with a mean of 55.Intracranial hypertension and seizures were the main symptoms encountered with 37% for each. Our diagnostic evaluation is based on CT scan which showed 50% of convexity meningiomas and 20% basal one .By using Simpson grading to assess the quality of surgical resection ,we found 64% of grade II and only 20% of grade I.A 12% of postoperative death rate is related on the substandard medical set and the lack of neuroanesthesists.\u0000\u0000Conclusion \u0000We outlined a program to improve the neurosurgery practice in Sub-Saharan countries.\u0000\u0000 Keywords : Afrique, meningiomes intracrâniens, neurochirurgie, Senegal, tumeurs, Africa, intracranial tumors, meningioma, neurosurgery, Senegal African Journal of Neurological Sciences Vol. 24 (1) 2005: pp. 45-554","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ao Molomo, J. Emejulu, A. Odukogbe, W. Shokunbi, Shokunbi Mt
{"title":"Cervical spine cord injury in pregnancy. Conservative management of 3 consecutive cases in Ibadan, Nigeria","authors":"Ao Molomo, J. Emejulu, A. Odukogbe, W. Shokunbi, Shokunbi Mt","doi":"10.4314/ajns.v25i2.7582","DOIUrl":"https://doi.org/10.4314/ajns.v25i2.7582","url":null,"abstract":"Study design A prospective study of 3 patients with incomplete cervical spinal cord injury in the 3rd trimester of pregnancy. Objectives To determine the effect of spinal cord injury and treatment with Gardner-Wells' Tong traction on pregnancy, labour and parturition; and ascertain the effectiveness and safety of this conservative form of management in pregnancy. Setting The patients were admitted and managed between September 2002 and May 2004, in the University College Hospital Ibadan, Nigeria - the major referral Centre in neurological diseases for about a quarter to a third of Nigeria's population. Methods From the point of admission into our Emergency Unit, data on each patient was documented prospectively until discharge to the out-patient clinic where each of them was followed up at appointed intervals. These data were then analyzed and compared with reports in literature. Results All the patients had good outcome from the conservative management as measured by complete neurological recovery, uneventful pregnancy and normal parturition. They however, seem to be disposed to pre-term labour, without being aware of the labour pains. Conclusion Spinal cord injury in pregnancy could be successfully manage with Gardner-Wells' Tong traction without deleterious effects on pregnancy and parturition, but appears to induce pre-term labour, associated with regional analgesia for labour pains. Etude prospecitve de 3 patientes presentant un traumatisme du rachis cervical au cours du 3eme trimestre de la grossesse. Determiner les effets du traumatisme rachi-medullaire au cours d'un traitement par traction cervicale de Gardner-Well dutant le travail et l'accouchement. Les patientes ont ete admises entre septembre 2002 et mai 2004 au centre hospitalier et universitaire d'Ibadan, Nigeria, centre referent neurochirurgical pour environ le tiers voire la moitie de la population du Nigeria. Les donnees cliniques et paracliniques ont ete recueillies de l'admission jusqu'a la sortie et au cours des consultations de controle puis analysees par rapport aux observations de la litterature. Tous les patients ont eu une evolution favorable avec le traitement conservateur que nous avons adopte, avec une recuperation neurologique complete, une absence d'evenement indesirable lors du travail, de l'accouchent et des suites de couches. Keywords : Cervical spinal cord. Gardner-Wells' Tongs traction. Third trimester gestation African Journal of Neurological Sciences Vol. 25 (2) 2006: pp. 6-12","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La Cryptococcose Neuro-Meningee Et L'infection Au Vih Dans Le Service De Medecine Du Centre Hospitalier Et Universitaire De Yaounde, Cameroun","authors":"J. Mbuagbaw, Biholong, A. Njamnshi","doi":"10.4314/AJNS.V25I2.7583","DOIUrl":"https://doi.org/10.4314/AJNS.V25I2.7583","url":null,"abstract":"Contexte La cryptococcose est une affection fungique frequente chez les personnes immunodeprimees pour laquelle peu d'etudes ont ete menees au Cameroun. But Decrire les aspects epidemiologiques, cliniques, biologiques et evolutifs de la cryptococcose neuro-meningee. Materiel et methodes Etude retrospective et descriptive menee a partir des dossiers medicaux des patients hospitalises pendant 57 mois dans le service de medecine interne du Centre Hospitalier et Universitaire de Yaounde (CHUY). Resultats Trente et trois cas de meningite cryptococcique ont ete diagnostiques sur les 3655 patients hospitalises. Le sexe masculin etait predominant (21 homme/12 femmes). L'âge moyen des patients etait de 39,81 ans. Les manifestations cliniques etaient : les cephalees (26 cas /33), la fievre (25 cas /33), les signes meninges (18 cas /33), les troubles de la conscience (9 cas/33) et les crises epileptiques generalisees (8 cas /33). L'infection par Mycobacterium tuberculosis etait la pathologie associee (10 fois/33) la plus frequente. La duree moyenne de l'evolution des symptomes avant le diagnostic etait de 14,93 jours. La serologie VIH etait positive chez 32 patients sur 33. La moyenne des lymphocytes CD4 etait de 29,94/mm3 et la mediane a 8 CD4 / mm3. Quatorze patients sur les 33 (42,2%) sont decedes dans un delai de 1 a 21 jours. Cette lourde mortalite est correlee au retard de mise en route d'un traitement adequat, a la coexistence d'une infection a Mycobacterium tuberculosis et a la mauvaise observance du traitement. Conclusion Chez tout patient presume infecte par le VIH, presentant un syndrome meninge franc ou fruste avec des cephalees, des troubles de la vigilance et des crises epileptiques, la realisation systematique d'une ponction lombaire et la recherche des cryptocoques dans le LCR sont recommandees afin de mettre en route rapidement un traitement adequat, afin de diminuer la mortalite qui reste elevee Background Cryptococcus neoformans is an important fungal pathogen in immunocompromised patients. Cryptococcal meningitis has not been well studied in Cameroon. Aim To describe the epidemiological, clinical, biological aspects and course of cryptococcal meningitis in patients admitted in the Yaounde University Teaching Hospital. Materials and methods: Retrospective and descriptive study conducted over a 57-month period in the Yaounde University Teaching Hospital. Results During this period, cryptococcal meningitis was diagnosed in 33 patients among the 3,655 patients who were hospitalised in the Internal Medicine service. There was a male predominance (21 males/ 12 females) in our study. The mean age of the patients was 39.81 years. The clinical features were variable: Headaches (26 cases /33), fever (25/33), signs of meningitis (18/33), altered consciousness (9/33) and generalised epileptic seizures (8/33). Mycobacterium tuberculosis infection was the most associated with cryptococcal meningitis (10 cases /33). The mean period of ev","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors For Epilepsy In Children With Cerebral Palsy","authors":"I. Lagunju, B. Adedokun, Fatunde Oj","doi":"10.4314/AJNS.V25I2.7585","DOIUrl":"https://doi.org/10.4314/AJNS.V25I2.7585","url":null,"abstract":"Background Cerebral palsy is a major cause of childhood disability and has been described as one of the three most common life-long developmental disabilities in childhood. It is more prevalent in the more socio-economically deprived populations of the world. Epilepsy is said to occur in 15-90% of children with cerebral palsy and this poses additional economic and psychological stress on affected children and their families. Objectives To describe the risk factors for epilepsy in children with cerebral palsy. Methods One hundred and seventy six children with cerebral palsy seen at the Paediatric Neurology clinic, University College Hospital, Ibadan, Nigeria over a period of two years were studied. The group with epilepsy was compared with that without epilepsy. Appropriate statistical tests were carried out using the SPSS 12 for windows software to identify significant predictors of epilepsy. Results Sixty five of the children studied had associated epilepsy, giving a prevalence rate of 36.9%. The significant predictors of epilepsy after adjusting for other variables were seizures in the first year of life and spastic hemiplegia. Neonatal seizures, home delivery and post infectious brain damage which were significantly independently associated with epilepsy were not significant following logistic regression analysis. Conclusion Epilepsy is a frequent problem in children with cerebral palsy. A history of neonatal seizures, occurrence of seizures in the first year of life, presence of spastic hemiplegia and post infectious brain damage all warrant a close evaluation and appropriate follow up for early detection of epilepsy in children with cerebral palsy. Introduction La paralysie cerebrale est une des causes majeures de handicaps chez l'enfant. Dans le monde entier, elle interesse surtout les couches socio- economiques defavorisees. L'epilepsie peut survenir chez 90 % des enfants presentant une paralysie cerebrale, entrainant ainsi des contraintes economiques et psychologiques chez des familles deja fort depourvues et eprouvees. L'objectif est de decrire les facteurs de risque de l'epilepsie chez les enfants atteints de paralysie cerebrale. Methode 176 enfants avec une paralysie cerebrale ont ete observes a la clinique neurologique pediatrique du centre hospitalier universitaire d'Ibadan, au Nigeria, sur une periode de 2 ans. Le groupe avec epilepsie a ete compare avec ceux qui n'etaient pas atteints par cette affection. Des tests statistiques appropries utilisant le SPSS 12 et un logiciel Windows a permis d'identifier les facteurs predictifs de l'epilepsie. Resultat 65 des patients etudies, avaient une epilepsie impliquant ainsi un taux de prevalence de 36.9 %. Les facteurs predictifs significatifs d'epilepsie apres ajustement des zones variables etaient : les crises lors de la premiere annee de la vie et l'hemiplegie spastique. Les crises neo-natales, l'accouchement a domicile et les sequelles cerebrales post infectieuses etaient","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"POSSIBLE MYASTHENIA AND LEMS IN THE SAME PATIENT :CASE REPORT AND REVIEW OF THE LITERATURE","authors":"V. Patel, P. Bill, A. Bhigjee","doi":"10.4314/AJNS.V23I2.7557","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7557","url":null,"abstract":"ABSTRACT \u0000Myasthenia gravis (MG) together with Lambert-Eaton myasthenic syndrome (LEMS) in the same patient is rarely described. This is a case report of a patient who initially presented with myasthenia gravis and later complicated with presumably auto-immune LEMS. The patient was noted to be HIV positive. The interest lies in the behaviour of MG in immunocompromised patients and the electrophysiological changes at the neuromuscular junction in patients with both MG and LEMS. We present a patient who is HIV positive with a long history of MG and a possibly a more recent diagnosis of LEMS. RESUME \u0000L'association myasthenie et syndrome de Lambert-Eaton chez un patient est rarement decrit. Nous rapportons le cas d'un patient, VIH positif, s'etant presente initialement par une myasthenie, completee ulterieurement par un syndrome de Lambert Eaton vraisemblablement d'origine auto-immune et discutons les liens eventuels, au plan pathogenique. Key words : Myasthenia Gravis, Lambert Eaton myasthenic syndrome, HIV, Myasthenie, syndrome de Lambert-Eaton, virus d'immunodeficience acquise, VIH African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Cissé, Y. Morel, A. Cissé, N. Câmara, B. Cisse, M. Doukoure, I. Souare, M. Barry, S. Camara, S. Kourouma, M. Diaby, L. Dasilva, A. Sylla, H. Dia
{"title":"GENERAL PARALYSIS IN A TROPICAL COUNTRY. STUDY OF 43 OBSERVATIONS","authors":"A. Cissé, Y. Morel, A. Cissé, N. Câmara, B. Cisse, M. Doukoure, I. Souare, M. Barry, S. Camara, S. Kourouma, M. Diaby, L. Dasilva, A. Sylla, H. Dia","doi":"10.4314/AJNS.V23I2.7556","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7556","url":null,"abstract":"PARALYSIE GENERALE EN MILIEU TROPICAL. ETUDE DE 43 OBSERVATIONS \u0000RESUME \u0000Description :Les auteurs rapportent une etude de 43 cas de paralysie generale, reveles par un syndrome dementiel et des formes atypiques notamment les troubles confusionnels repetitifs et des crises epileptiformes. \u0000Objectif : L'objectif de cette etude est de reevaluer cette pathologie du point de vue clinique et paraclinique en milieu tropical. \u0000Methode : Il s'agit d'une etude prospective. Le diagnostic a repose sur la positivite des reactions serologiques ( VDRL-TPHA) dans le sang et le liquide cephalo-rachidien, la presence d'une hypercellularite a predominance lymphocytaire et d'une hyperproteinorachie. \u0000Resultats : Les troubles cognitifs et moteurs, les etats confusionnels repetitifs et les crises epileptiques constituent les formes cliniques dominantes de debut. Chez tous les patients, le scanner a mis en evidence une discrete dilatation ventriculaire diffuse et un elargissement des sillons de la convexite. Le trace electroencephalographique etait anormal dans pres de 67% des cas. SUMMARY \u0000Description : The authors report a study of 43 cases of general paralysis revealed by some mental disorders and atypical forms notably repeater confessional disorders and some seizure-like attacks. \u0000Objective : The goal of this study is to revalue this pathology from the clinical and paraclinic point of view in tropical medium. \u0000Method : In this prospective study, the diagnosis was based on the serologic tests (VDRL-TPHA) in the blood and the cerebrospinal fluid (CSF); CSF cell count with lymphocyte predominance ; protein level in the fluid. \u0000Result : The diagnosis was based on the serologic tests (VDRL-TPHA) in the blood and the cerebrospinal fluid(CSF); high CSF cell count with lymphocyte predominance; high protein level in the fluid. The cogniture and motor troubles, the repeated confusion status and the epileptic seizures constitute the dominant clinical forms of the onset. In all the patients, the CT-scan revealed discrete diffuse ventricular dilation and widening of the grooves of the convexity. The electroencephalographic traces were abnormal in 67% of the cases. Key Words: Afrique, Guinee, paralysie generale, syphilis nerveuse, Africa, Guinea, general paralysis, neurosyphilis African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"39 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Urowayino Onifade, F. E. A. Lesi, V. C. Ezeaka, Adenike Olufunmilayo Grange
{"title":"SEQUELLES NEUROLOGIQUES CHEZ DES ENFANTS ATTEINTS D'UNE MENINGITE PURULENTE DANS UN CENTRE TERTIAIRE A LAGOS (NIGERIA)","authors":"Elizabeth Urowayino Onifade, F. E. A. Lesi, V. C. Ezeaka, Adenike Olufunmilayo Grange","doi":"10.4314/AJNS.V23I2.7555","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7555","url":null,"abstract":"NEUROLOGICAL SEQUELAE IN CHILDREN WITH PYOGENIC MENINGITIS IN A TERTIARY CENTRE IN LAGOS (NIGERIA \u0000ABSTRACT \u0000Background: Neurological sequelae following childhood bacterial meningitis are common particularly in the presence of delayed diagnosis and treatment. The latter is commonplace with meningitis in developing countries like Nigeria but information on the incidence and prevalence rates of consequent neurological sequelae is rare. \u0000Objective: We herein document the prevalence of such sequelae in children following admission for pyogenic meningitis and describe associated risk factors. \u0000Methods: We retrospectively reviewed forty-nine children managed for acute pyogenic meningitis at the Lagos University Teaching Hospital (LUTH) over a 10-year period. Information on biodata, clinical features, pre–admission treatment, investigation results, treatment, and duration of hospitalization were extracted from their case records and analysed. \u0000Results: Thirty-two (65.3%) of these children had obvious neurological sequelae. These included neuro-motor disorders (31%), hydrocephalus (28%), hearing disorders (25%), speech and language problems (25%), recurrent seizures (22%), mental retardation (22%), visual defects (19%) and behavioural problems (3%). All ages were affected but more commonly infants. Sequelae occurred in multiples. \u0000Children with sequelae tended to have had prior hospitalization and treatment. However no clinical or socio-economic factors showed significant relationship with the development of neurological sequelae. \u0000Conclusions: The distribution of sequelae in our study is similar to findings of other authors but shows a higher prevalence thus further confirming the need for primary prevention of this disease and for prompt and adequate treatment of cases. We recommend early screening of survivors for sequelae so that adequate rehabilitation can be planned. RESUME \u0000Introduction: Les sequelles neurologiques secondaire a une meningite bacterienne au cours de l'enfance sont frequentes en particulier lorsque le diagnostic et le traitement sont retardes. \u0000Objectif: Nous rapportons dans ce travail les aspects sequellaires neurologiques observes chez les enfants hospitalises pour meningite pyogenique en relevant les facteurs de risque lies a cette affection. \u0000Methode: Nous avons passe en revue retrospectivement, quarante neuf enfants traites atteints de la meningite purulante au centre hospitalier universitaire de Lagos (LUTH) au cours d'une periode de 10 ans. Les informations cliniques, paracliniques et therapeutiques tires de leurs dossiers medicaux ont ete analyses. \u0000Resultats: Trente deux soit 65,3% des cas enfants presentaient des sequelle neurologicales: troubles neuro-moteurs (31%), hydrocephalie (28%), troubles de l'ouie (25%), troubles du language et (25%), crise chronique (22%), retard mentale (22%), troubles visuelles (19%) et de comportement (3%). Aucun facteur clinique, socio-economique n'a pas ete releve et relie avec la survenue d","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SYNDROME DE GELINEAU. A PROPOS D'UN CAS NIGERIAN ET REVUE DE LA LITERATURE","authors":"Mayowa O. Owolabi, Adesola Ogunniyi","doi":"10.4314/AJNS.V23I2.7558","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7558","url":null,"abstract":"GELINEAU SYNDROME: LITERATURE REVIEW AND MANAGEMENT OF A NIGERIAN TEENAGER SUMMARY \u0000Gelineau syndrome is a rare disorder with a hospital prevalence of 0.026% in Nigeria. A 14-year old Nigerian with narcolepsy, cataplexy, visual hypnagogic hallucinations and hypnapompic sleep paralysis is presented here. He had a Multiple Sleep Latency Test done using the Carscadon protocol. With the exclusion of other differential diagnoses, this patient satisfied the DSM IV, Carscadon's Multiple Sleep Latency Test and the Silber Category A criteria for definite narcolepsy. He was controlled on methylphenidate and programmed daily naps. RESUME \u0000Au Nigeria, le syndrome de Gelineau est un trouble rare avec une prevalence hospitaliere de 0.026%. Nous etudions ici le cas d'un patient nigerien âge de 14 ans atteint de narcolepsie, de cataplexie, d'hallucinations hypnagogiques visuelles et de paralysie du sommeil hypnopompique. Il a ete effectue un test de latence multiples d'endormissement en utilisant le protocole de Carscadon. En excluant d'autres diagnostics differentiels, ce patient repond au DSM IV, le test de latence multiple d'endormissement de Carscadon et du Silber Categori un critere determinant la narcolepsie. Le patient a ete mis sous methylphenidate et des siestes quotidiennes lui furent preconisees. Key Words: Cataplexy, Narcolepsy, Nigeria, Afrique, Cataplexie, narcolepsie, Nigeria African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Djientcheu, A. K. Njamnshi, P. Ongolo-Zogo, L. Dongmo, J. Eloundou, B. Rilliet, W. Muna, A. Essomba, M. Sosso
{"title":"HYDROCEPHALIE: UN CAS RARE DE TOXOPLAMOSE CEREBRALE DANS LE CADRE D'UN SYNDROME D'IMMUNO-DEFICIENCE ACQUISE","authors":"V. Djientcheu, A. K. Njamnshi, P. Ongolo-Zogo, L. Dongmo, J. Eloundou, B. Rilliet, W. Muna, A. Essomba, M. Sosso","doi":"10.4314/AJNS.V23I2.7559","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7559","url":null,"abstract":"HYDROCEPHALUS: A RARE PRESENTATION OF CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME \u0000SUMMARY \u0000The incidence of HIV infection and the neurological complications are increasing, especially in developing countries. Hydrocephalus due to cerebral toxoplasmosis is very rare and only 7 cases have been reported in the literature . The authors report a case of hydrocephalus related to toxoplasmosis of the 4th ventricles in a HIV patient successfully treated medically without shunting. The mechanism of the hydrocephalus is a necrotizing ependymitis and plexitis obstructing the CSF flow although the cerebral parenchyma has a normal CT appearance in many cases. CNS toxoplasmosis should be ruled out in any immuno-deficient patient with hydrocephalus of unknown origin. The permanent CSF shunting may not be necessary in hydrocephalus due to CNS toxoplasmosis, and external CSF shunting may only rarely be needed. RESUME \u0000Les auteurs presentent un cas d'hydrocephalie associee a une toxoplasmose du IV eme ventricule chez un patient HIV positif, traite medicalement avec succes, sans derivation du LCS. Le mecanisme de l'hydrocephalie est une ependymite et une plexite necrosante obstruant la circulation du LCS, meme si le parenchyme cerebral apparait normal au scanner dans plusieurs cas. Une toxoplasmose du systeme nerveux central doit etre recherchee chez tout patient immunodeprime avec une hydrocephalie d'etiologie indeterminee. Une derivation permanente du LCS ne serait pas necessaire au cours de l'hydrocephalie entrant dans ce cadre. La derivation ventriculaire externe peut etre implantee dans de rares conditions. Key Words: CNS toxoplasmosis, AIDS, hydrocephalus, medical treatment, Cameroon, Afrique, Cameroun, Hydrocephalie, Toxoplasmose, VIH, SIDA African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farid Wagdi, C. Debrock, Karim Farid, B. Bouteille, P. Preux
{"title":"IMPACT OF AN ANTI-HELMINTHIC TREATMENT ON THE COURSE OF EPILEPSY IN THE NEUROPSYCHIATRY DEPARTMENT OF ALEXANDRIA IN EGYPT : A LINK BETWEEN ASCARIDIASIS AND EPILEPSY ?","authors":"Farid Wagdi, C. Debrock, Karim Farid, B. Bouteille, P. Preux","doi":"10.4314/AJNS.V23I2.7554","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7554","url":null,"abstract":"ASSOCIATION ENTRE TRAITEMENT DE L'ASCARIDIOSE ET DIMINUTION DE LA FREQUENCE DES CRISES CHEZ LES PATIENTS EPILEPTIQUES A ALEXANDRIE (EGYPTE) \u0000RESUME \u0000Description et objectif: ce travail recherche une association entre ascaridiose et epilepsie. \u0000Methodes: une etude d'impact du traitement anti-helminthique a ete realisee dans le service de Neuropychiatrie d'un hopital general d'Alexandrie en Egypte. \u0000Resultats: 537 patients epileptiques ont ete inclus. Le niveau d'infection d'ascaridiose etait severe a modere pour 68 % d'entre eux. Apres traitement anti-helminthique, le nombre moyen de crises d'epilepsie partielle s'est reduit de 10 % (p \u0000Conclusion: cette etude donne des arguments indirects incitant a poursuivre les etudes epidemiologiques ou physiopathologiques a la recherche d'un lien causal entre ascaridiose et epilepsie. SUMMARY \u0000Background and objective: this work looks for a link between ascaridiasis and epilepsy. \u0000Methods: This work has looked for the impact of an anti-helminthic treatment on the course of epilepsy and was performed in the Neuropsychiatry department of a general hospital of Alexandria in Egypt. \u0000Results: 537 patients with epilepsy have been included. The level of ascaridiasis infection was severe to moderate for 68 % of them. After anti-helminthic treatment, the average number of partial epilepsy fits has reduced in 10 % (p \u0000Conclusion: this study gives indirect arguments prompting to continue epidemiological or pathophysiological studies in search of a correlation between ascaridiasis and epilepsy. Keywords : Afrique, ascaridiose, Egypte, epilepsie, Africa, ascaridiasis, Egypt, epilepsy African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"234 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}