Journal of the ASEAN Federation of Endocrine Societies最新文献

{"title":"Corrigendum on the article entitled, <i>'Thyroid Imaging Reporting and Data System (TIRADS) in Stratifying Risk of Thyroid Malignancy at The Medical City,'</i> by Dy et al., published in JAFES Vol. 32. No. 2.","authors":"Joanna Grace Dy, Ruben Kasala, Christy Yao, Renncee Ongoco, Dondee Jules Mojica","doi":"10.15605/jafes.041.02.6564","DOIUrl":"10.15605/jafes.041.02.6564","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.15605/jafes.032.02.03.].</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"167-170"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phosphaturic Mesenchymal Tumor: From Invisibility to Bedridden Morbidity.","authors":"Ramita Mukherjee, Santosha Kumar Pattashanee, Brijesh Kumar Singh, Asuri Krishna, Sushant Soren, A Nishikant Damle, M C Sharma, V Seenu","doi":"10.15605/jafes.041.02.5185","DOIUrl":"10.15605/jafes.041.02.5185","url":null,"abstract":"<p><p>Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by fibroblast growth factor 23 (FGF23) secreting phosphaturic mesenchymal tumors. We report a 53-year-old man with progressive osteomalacia resulting in bedridden status. Renal phosphate wasting despite normal vitamin D, intact parathormone, and renal function raised suspicion of TIO, confirmed by elevated FGF23. However, the occult tumor was localized only by Ga-68 DOTANOC wholebody PET-CT, highlighting the diagnostic challenges in TIO.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"118-123"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of a Giant Prolactinoma With Bromocriptine Leads to Marked Improvement in Visual Field Defect.","authors":"Mark Anthony Sandoval, Juan Silvestre Pascual, Servando Andres Liban","doi":"10.15605/jafes.041.02.6297","DOIUrl":"10.15605/jafes.041.02.6297","url":null,"abstract":"","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"159-161"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting Long-Term Outcomes and Quality of Life of Patients with Pituitary Adenoma After Endoscopic Endonasal Transsphenoidal Surgery (EETS) Using the SF-36 Questionnaire (Indonesian Version).","authors":"Novie Rahmawati Zirta, Tri Juli Edi Tarigan, Rudi Putranto, Murdani Abdullah, Budiman, Arya Govinda Roosheroe, Edy Rizal Wahyudi","doi":"10.15605/jafes.041.02.6141","DOIUrl":"10.15605/jafes.041.02.6141","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the quality of life (QoL) of patients with pituitary adenoma following Endoscopic Endonasal Transsphenoidal Surgery (EETS) and identify factors influencing long-term outcomes.</p><p><strong>Methodology: </strong>A cross-sectional study was conducted at the National Brain Center Hospital, Indonesia. Secondary data were obtained from medical records and the pituitary registry, while primary data were collected through patient interviews using the validated Indonesian version of the SF-36 questionnaire. Statistical analyses included univariate, bivariate, and multivariate linear regression with the backward method to identify independent predictors of QoL.</p><p><strong>Results: </strong>Among 90 patients (45 males, 45 females), visual disturbances (85.6%) and hormonal deficiencies (93.3%) were common. Most had macroadenomas (95.6%) and received combined EETS and medical therapy (62.2%). Physical component scores (PCS) exceeded mental component scores (MCS). The highest domain scores were in physical functioning and role-emotional functioning; vitality and mental health had the lowest scores. Gender was significantly associated with four QoL domains, and hormonal deficiency affected the role-emotional domain. Multivariate analysis identified gender and hormonal deficiency as predictors of MCS (R² = 74%); no factors significantly influenced PCS.</p><p><strong>Conclusion: </strong>Postoperative QoL after EETS is generally good in physical aspects but suboptimal in mental health. Gender and hormonal deficiency affect mental QoL, highlighting the need for holistic, long-term care strategies.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"7-15"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Associated Factors of Erectile Dysfunction Among Filipino Men With Type 2 Diabetes Mellitus in a Tertiary Hospital in San Juan City, Metro Manila, Philippines.","authors":"Joebeth Tabora, Ramon Paolo Abiera, Harold Henrison Chiu, Juan Maria Ibarra Co, Benjamin Ramos, Rosa Allyn Sy","doi":"10.15605/jafes.041.02.6147","DOIUrl":"10.15605/jafes.041.02.6147","url":null,"abstract":"<p><strong>Background: </strong>Erectile dysfunction (ED) is a common complication among men with Type 2 Diabetes Mellitus (T2DM), but updated data from the Philippines remain limited. This study determined the prevalence of ED and evaluated associated clinical and socioeconomic factors among Filipino men with T2DM.</p><p><strong>Methodology: </strong>We conducted a cross-sectional study among 384 adult Filipino men with T2DM recruited from private clinics, an outpatient service clinic, and an affiliated community clinic of Cardinal Santos Medical Center. ED was assessed using the International Index of Erectile Function-5 (IIEF-5). Comparative analyses between participants with and without ED were performed, followed by multivariable logistic regression analysis. Results are presented as adjusted odds ratios (AORs) with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>The prevalence of erectile dysfunction (ED) among Filipino men with T2DM in this study was 88.02% (338/384; 95% CI: 84.4-91.1). Common comorbidities in the study population included hypertension (67.45%), dyslipidemia (44.53%), and coronary artery disease (26.56%). Regarding glycemic control, only 30.31% of participants had an HbA1c level <7%. Participants with ED were significantly older than those without ED (median age: 60 [IQR 17] vs 48 years [IQR 15], p <0.001) and were more likely to have a longer duration of diabetes. On multivariable analysis, dyslipidemia remained independently associated with higher odds of ED (AOR = 2.57, 95% CI: 1.20-5.53; p = 0.015), whereas higher socioeconomic status was associated with lower odds of ED (AOR = 0.31, 95% CI: 0.13-0.75; p = 0.010).</p><p><strong>Conclusion: </strong>ED was highly prevalent among Filipino men with T2DM included in this study. Dyslipidemia and socioeconomic status were independently associated with ED and may help identify patients who could benefit from more thorough screening. Further studies involving larger cohorts and improved sampling methods are needed to validate these findings and better understand the factors underlying the high prevalence of ED observed in this population.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"42-51"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Hyperinsulinism With Paternally Inherited <i>ABCC8</i> Variants: A Single Center Experience Over a Decade in Singapore.","authors":"Cherie Chua, Daniel Chan, Ai Ling Koh, Suresh Chandran, Fabian Yap","doi":"10.15605/jafes.041.02.6197","DOIUrl":"10.15605/jafes.041.02.6197","url":null,"abstract":"<p><p><i>ABCC8</i> pathogenic variants have been found to cause neonatal diabetes mellitus (NDM), maturity-onset diabetes of the young (MODY) and congenital hyperinsulinism (CHI), depending on the nature of the mutation. Few studies have reported on the carrier frequency of CHI-related <i>ABCC8</i> variants. In Singapore, the carrier rate is 1 in 754. Paternally inherited <i>ABCC8</i> recessive variants have been classically associated with focal lesions causing CHI. In our case series of five patients with paternally inherited <i>ABCC8</i> variants, one patient had a second maternally inherited recessive variant, making him a compound heterozygous genotype presenting with severe, neonatal onset, diffuse disease that was not responsive to diazoxide. The remaining four patients had a single paternally inherited <i>ABCC8</i> variant, of which three were previously reported to be recessive variants-only 1 had a focal lesion while the rest had diffuse disease. A comprehensive review of our cases suggests that patients with paternally inherited <i>ABCC8</i> variants, whether autosomal recessive, heterozygous, or associated with genetic syndromes, were heterogeneous in their clinical manifestations and cannot be reliably distinguished based on their initial clinical presentation. A deeper understanding of the genotype-phenotype correlation of <i>ABCC8</i>-related CHI will require further research and functional analyses. Both a genetic diagnosis and imaging using ¹⁸F-DOPA-PET should be pursued in a timely manner once diazoxide unresponsiveness has been established. Single-stage near-total pancreatectomy may be considered for patients with diffuse disease.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"151-158"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors Associated With Multidrug Resistant Organism (MDRO) Isolates in Infected Diabetic Foot Ulcers (DFU): An Analytical Cross-sectional Study.","authors":"Athena Jan Patawaran, Daveric Pagsisihan","doi":"10.15605/jafes.041.02.6303","DOIUrl":"10.15605/jafes.041.02.6303","url":null,"abstract":"<p><strong>Background: </strong>Increasing use and abuse of antibiotics has led to a rise in multidrug resistant organisms (MDRO) isolates among infected diabetic foot ulcers (DFUs) and is seen in more than half of all diabetic foot infection cases. This study aimed to identify risk factors for MDRO infection since there are no Filipino studies currently available to establish an association.</p><p><strong>Methodology: </strong>A cross-sectional, analytical study was conducted to evaluate risk factors for MDRO in DFUs. Adult patients admitted in a tertiary hospital from January 2019 - December 2023 for DFU were included in the study. Based on retrospective chart review, patients with DFU described to be infected with accompanying superficial or deep wound cultures were studied. Patients were classified under the MDRO-positive group if their cultures reported any of the following organisms: methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), extended-spectrum beta-lactamases (ESBL), amp C and carbapenamases-producing <i>Enterobacteriaceae</i>, Metallo-beta-lactamases (MBL)-producing <i>Pseudomonas, Acinetobacter</i> species, or any isolate with at least one drug resistance in three different antibiotic classes. Those who did not fall into this definition, including cultures without growth, were classified under the MDRO-negative group. Clinical risk factors and pertinent laboratory findings were obtained from their data.</p><p><strong>Results: </strong>One hundred fifty-one (151) patients were included in the study and 52 (34.43%) patient had MDRO isolates. The most common isolates seen were <i>Klebsiella pneumoniae</i> for gram-negative organisms and <i>Staphylococcus aureus</i> for gram-positive organisms. For gram-negative isolates, erythromycin had the most resistance at 17.53% followed by oxacillin and clindamycin both at 13.4%. For gram-positive isolates, highest resistance were seen with ampicillin at 18.99% followed by cefuroxime at 13.57% and amoxicillin-clavulanate at 11.63%.Higher ulcer grade (Crude OR = 1.11 [95% CI 1.00 - 1.23], <i>p</i>-value 0.04; Crude OR = 1.29, [95% CI 1.04 - 1.60], <i>p</i>-value 0.02), as well as previous admission for diabetic foot ulcer (Crude OR = 2.28, [95% CI 1.10 to 4.73], <i>p</i>-value 0.04) were associated with multidrug resistance. Logistic regression showed that only a previous admission had significant association for MDRO positivity (Adjusted OR = 3.00 [95% CI: 1.04 - 8.62], <i>p</i>-value 0.04).</p><p><strong>Conclusion: </strong>There is a high burden of multidrug resistant organism infection in diabetic foot ulcers with significant association in higher ulcer grades. A previous admission for diabetic foot ulcer significantly increases the odds for MDRO infection in succeeding diabetic foot infections.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"35-41"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitudes and Practices of Healthcare Workers regarding Obesity: A Survey at a Tertiary Hospital in Vietnam.","authors":"Tuan Doan Minh Tran","doi":"10.15605/jafes.041.02.5583","DOIUrl":"10.15605/jafes.041.02.5583","url":null,"abstract":"<p><strong>Background: </strong>The global prevalence of obesity has tripled over the past four decades, with an estimated one-third of the world's population currently classified as overweight or obese. Obesity is recognized as one of the most urgent global public health challenges, with increasing rates observed in both developed and developing countries. In Southeast Asia, the burden of obesity is particularly concerning due to the coexistence of undernutrition and overnutrition, creating a double burden of disease. Healthcare workers play a critical role in the prevention, early detection and management of obesity. However, many healthcare workers lack updated knowledge on obesity, which is often associated with insufficient or inappropriate management.</p><p><strong>Objective: </strong>To assess the knowledge, attitudes, and practices (KAP) of healthcare workers toward obesity management at a tertiary hospital in Ho Chi Minh City, Vietnam, and to identify associated barriers and interprofessional differences.</p><p><strong>Methodology: </strong>A cross-sectional study was conducted among 232 healthcare workers using a 22-item structured, selfadministered questionnaire. The survey evaluated knowledge of obesity risk factors and treatments, attitudes toward patient responsibility and stigma, and clinical practices such as screening, counseling and referrals. Associations between professional roles and responses were analyzed using Chi-square and Fisher's exact tests.</p><p><strong>Results: </strong>Among 232 participants (37.5% were physicians and 62.5% were non-physician healthcare workers), only 63.8% [95% CI: 57.3-70.3%] recognized obesity as a chronic disease and fewer than half were aware of approved pharmacotherapies. While most workers believed they could assist patients, a significant majority (79.7% [95% CI: 75.0- 84.9%]) attributed weight loss primarily to patient responsibility, indicating widespread implicit weight bias. Furthermore, physicians reported significantly higher odds of inadequate knowledge of weight management compared to other staff (OR = 4.5, 95% CI: 2.1-9.5).</p><p><strong>Conclusion: </strong>Significant knowledge gaps and implicit weight biases persist among healthcare workers regarding obesity management. Addressing these educational and systemic barriers through specialized training and multidisciplinary care models in Vietnam can provide a crucial framework for improving obesity management across rapidly urbanizing Southeast Asian nations facing similar metabolic crises.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"24-32"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Through a Clearer Glass: The Endocrine Window in Sharper Focus: Measurement, the Uncommon, and the Discipline of Seeing Clearly.","authors":"Cecilia A Jimeno","doi":"10.15605/jafes.041.02.6570","DOIUrl":"https://doi.org/10.15605/jafes.041.02.6570","url":null,"abstract":"","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"5-6"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dapagliflozin Alone or Combined With Semaglutide: Cardiovascular and Renal Outcomes Among Patients With Type 2 Diabetes Mellitus in a 6-Month Real-World Retrospective Cohort Study in Saudi Arabia.","authors":"Rasmah Alharajin, Muneera AlTaweel, Maram AlSubaiee, Saleh Al Makhloof, Abdulmohsen Almusaad, Abdulrahman Alarfaj, Ahmad AlKhayyal, Noor Altharman, Ahmed Alalawi, Noora Almannai, Munirah Alohaymid, Afnan Alsaad, Turkiah Alotaibi, Reem Alkhaldi, Ghusoon Almoaibed, Jawaher Alrashada, Abdullatif Alarfaj, Turki Alqarni, Abdullah Alshahrani, Ibraheem Aldossary, Seham Khashwayn, Ali Al Qarni, Yaqob Taleb, Mareyah Alshaikh Husain","doi":"10.15605/jafes.041.02.6171","DOIUrl":"10.15605/jafes.041.02.6171","url":null,"abstract":"<p><strong>Introduction: </strong>Type 2 diabetes mellitus (T2DM) is a growing global health concern linked to increased cardiovascular and renal complications. Two emerging therapeutic classes, sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon like peptide-1 receptor agonists (GLP-1 RAs), have shown independent cardiometabolic benefits. However, limited realworld data exist on the comparative impact of combining these therapies versus using SGLT2i alone.</p><p><strong>Objective: </strong>To compare the cardiovascular and renal outcomes of dapagliflozin monotherapy versus combination therapy with once-weekly injectable semaglutide among patients with type 2 diabetes mellitus (T2DM).</p><p><strong>Methodology: </strong>In this retrospective cohort study, 539 adult patients with confirmed type 2 diabetes mellitus (T2DM; baseline HbA1c ≥6.5%) treated at King Abdulaziz Hospital, Al-Ahsa, were followed over six months. Patients received either dapagliflozin alone or in combination with semaglutide. Generalized Estimating Equations (GEE) were used to assess changes in glycemic control, cardiovascular events, lipid profile, and renal function, adjusting for time and sex.</p><p><strong>Results: </strong>Both groups showed significant metabolic improvements over six months. Dapagliflozin monotherapy was associated with greater HbA1c reduction. Combination therapy was associated with higher HDL levels, improved eGFR, and a lower relative risk of heart failure (RR = 0.43, <i>p</i> = 0.04); the reduction in myocardial infarction risk (RR = 0.61, <i>p</i> = 0.13) did not reach statistical significance. No significant difference was observed in stroke risk. Most cardiovascular and renal markers improved modestly.</p><p><strong>Conclusion: </strong>Combination therapy was associated with favorable renal outcomes and a reduction in heart failure risk, despite inferior glycemic control and a non-significant trend toward reduced myocardial infarction risk. These findings suggest potential complementary effects of SGLT2i and GLP-1 RA treatment in high-risk patients. However, due to the retrospective, non-randomized design, causal relationships cannot be inferred, and residual confounding may exist. Prospective trials are warranted to confirm these associations and guide treatment optimization.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"41 2","pages":"75-84"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}