{"title":"Validation of the Filipino Version of the Diabetes Distress Scale for Adult Patients with Diabetes seen at the Outpatient Department of a Tertiary Government Hospital in Quezon City, Philippines.","authors":"Margarette Rose Pajanel, Irish Judy Gonzales","doi":"10.15605/jafes.040.01.05","DOIUrl":"10.15605/jafes.040.01.05","url":null,"abstract":"<p><strong>Introduction: </strong>Caring for persons with diabetes involves a holistic approach. Addressing diabetes distress is crucial to achieve optimal health outcomes for persons with diabetes. This study aims to validate a Filipino version of the diabetes distress scale (DDS).</p><p><strong>Methodology: </strong>We conducted forward and backward translations to construct a Filipino version from the validated English questionnaire. We performed statistical analysis to check internal consistency and validation and to correlate diabetes distress with glycemic control based on the subjects' HbA1c levels.</p><p><strong>Results: </strong>We included one hundred and seventy patients (170) seen at the Outpatient Diabetes Clinic in the analysis. Of the participants, 13 (7.6%) have Type 1 Diabetes Mellitus (T1DM), while the rest have Type 2 (T2DM). We found physician distress (PD) to be significantly associated with having T1DM. All domains in the Filipino DDS showed good internal consistency, ranging from 0.81 to 0.85. We used factor analysis to extract four factors similar to the original diabetes distress scale. We did not find any significant correlation between diabetes distress and HbA1c level.</p><p><strong>Conclusion: </strong>The Filipino DDS showed good internal reliability and had consistent results similar to the original diabetes distress scale. However, we did not find a significant correlation between diabetes-related distress and the HbA1c level.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"61-71"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Consensus for Pituitary Adenoma Diagnosis in Indonesia.","authors":"Dicky Levenus Tahapary, Selfy Oswari, Maya Kusumawati, Dian Anindita Lubis, Tania Tedjo Minuljo, Reyhan Eddy Yunus, Henry Kodrat, Affan Priyambodo Permana, Martha Rosana, Johanes Purwoto, Leny Puspitasari, Hermina Novida, Himawan Sanusi, Syntia Nusanti, Tri Juli Edi Tarigan, Pradana Soewondo, Ketut Suastika","doi":"10.15605/jafes.040.01.03","DOIUrl":"10.15605/jafes.040.01.03","url":null,"abstract":"<p><p>Pituitary adenomas account for 10 to 15% of all intracranial masses and are the most common type of pituitary disorder. Their clinical manifestations can vary based on the tumor size and whether they secrete excess hormones. Occasionally, they are incidentally diagnosed following an imaging procedure for other indications (pituitary incidentaloma). The Pituitary Working Group of the Indonesian Society of Endocrinology has identified pituitary adenoma as a priority and has called for the development of updated evidence-based practice guidelines. These guidelines aim to provide evidence-based, comprehensive and multidisciplinary recommendations for diagnosing pituitary adenomas in Indonesia and to navigate the limitations of diagnosing pituitary adenomas in Indonesia.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"8-13"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oscillation between Hyperthyroidism and Hypothyroidism in an Adolescent Female with Graves' Disease.","authors":"Yee Lin Lee","doi":"10.15605/jafes.040.01.07","DOIUrl":"10.15605/jafes.040.01.07","url":null,"abstract":"<p><p>Graves' disease (GD) presenting as fluctuations between hyperthyroidism and hypothyroidism is a rare phenomenon and poses a diagnostic challenge. A 14-year-old female with GD, initially thought to have Hashimoto's thyroiditis presented with a goiter and oscillating thyroid function over the course of 4 years. This case depicts a case of GD with oscillating thyroid function and stresses the importance of TSH receptor antibodies (TRAb) in the evaluation of patients with hyperthyroidism without Graves' ophthalmopathy.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"117-120"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paraganglioma in Pregnancy with Recurrent Pregnancy Loss: A Case Report.","authors":"Wee Mee Cheng, Zanariah Hussein","doi":"10.15605/jafes.040.01.09","DOIUrl":"10.15605/jafes.040.01.09","url":null,"abstract":"<p><p>Due to its rarity, pheochromocytoma or paraganglioma (PPGL) in pregnancy is often not timely diagnosed, thus resulting in high materno-fetal complications. We report a 28-year-old female who presented with paroxysmal symptoms and severe hypertension during early pregnancy. Biochemical confirmatory tests and localization imaging were delayed due to multiple factors. She suffered from two pregnancy losses before she had resection of the paraganglioma.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"98-103"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perioperative Complications Associated with Routine Preoperative Glucocorticoid Use Among Patients Undergoing Pituitary Surgery with Normal Preoperative HPA Axis: A Retrospective Cohort Study.","authors":"Franz Michael Magnaye, Elizabeth Paz-Pacheco","doi":"10.15605/jafes.040.01.06","DOIUrl":"10.15605/jafes.040.01.06","url":null,"abstract":"<p><strong>Objective: </strong>This study determined the incidence of perioperative complications associated with routine preoperative glucocorticoid use in patients undergoing pituitary surgery with normal preoperative hypothalamo-pituitary-adrenal axis (HPA axis).</p><p><strong>Methodology: </strong>From 2011-2021 retrospective chart review, 243 patients undergoing pituitary surgery with normal preoperative HPA axis were analyzed into 2 groups: 1) with preoperative steroids; and 2) without preoperative steroids. Development of postoperative complications was subsequently evaluated.</p><p><strong>Results: </strong>Incidence of primary composite postoperative complications of in-hospital mortality, postoperative infection and postoperative diabetes insipidus (DI) was significantly increased among those who had preoperative steroids compared to those without (58.33% versus 33.33%, <i>p</i>-value 0.004) with an adjusted odds ratio of 2.90 (CI 1.29 to 6.53, <i>p</i>-value 0.010). Among the components of the composite outcome, post-operative DI was statistically higher among those who were given preoperative steroids (52.45% versus 28.21%, <i>p</i>-value 0.006) with an adjusted OR of 3.31 (CI 1.43 to 7.67, <i>p</i>-value 0.005). The incidence of postoperative adrenal insufficiency was similar between the 2 groups (20.15% with steroids versus 8.70% without steroids, <i>p</i>-value 0.258).</p><p><strong>Conclusion: </strong>Among patients undergoing pituitary surgery with normal preoperative HPA axis, routine preoperative steroids use was associated with an increased risk of composite postoperative complications.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"89-96"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nam Quang Tran, Dao Nguyen Thi Bich, Thu Nghiem Nguyet, Tuan Nguyen Anh, Nghi Le Huu, Thanh Dau Ba, YouSun Ha
{"title":"Perceptions, Attitudes, Behaviours and Barriers in Obesity Care: Findings from the ACTION-Vietnam Study.","authors":"Nam Quang Tran, Dao Nguyen Thi Bich, Thu Nghiem Nguyet, Tuan Nguyen Anh, Nghi Le Huu, Thanh Dau Ba, YouSun Ha","doi":"10.15605/jafes.040.01.17","DOIUrl":"10.15605/jafes.040.01.17","url":null,"abstract":"<p><strong>Objective: </strong>The ACTION Asia Pacific (ACTION-APAC) study was designed to identify the perceptions, attitudes, behaviours and potential barriers to effective obesity management in people with obesity (PwO) and healthcare professionals (HCPs) in nine countries of Southeast Asia. This study represents the findings in Vietnam.</p><p><strong>Methodology: </strong>This cross-sectional, non-interventional study gathered information from Vietnamese PwO (n = 1000) and HCPs (n = 200) via an anonymous online survey between April and May 2022.</p><p><strong>Results: </strong>The majority of PwO (67%) and HCPs (80%) believed that obesity is a chronic disease that profoundly impacts a person's overall health (76% PwO, 81% HCPs). About 58% of PwO agreed that managing weight loss was solely their responsibility. Meanwhile, 76% of HCPs believed they should actively contribute to their patients' weight loss efforts. Most of the PwO (82.7%) had attempted weight loss with an average of four times. PwO and HCPs cited lack of exercise (63% vs. 86%) and lack of motivation (60% vs. 80%) as the principal barriers to weight loss. HCPs cited PwOs' lack of interest (52%) and motivation to lose weight (45%) as top reasons for not discussing weight.</p><p><strong>Conclusion: </strong>The study emphasised raising awareness for obesity management among PwO and HCPs and suggested early weight management conversations with HCPs.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"32-44"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamad Hafis Bin Razali, Suhaimi Hussain, Mohd Hazman Bin Kamaruzaman, Nurul Jannah Binti Ambak
{"title":"The Prevalence of Hypophosphatemia and its Associated Risk Factors in Diabetic Ketoacidosis Patients.","authors":"Mohamad Hafis Bin Razali, Suhaimi Hussain, Mohd Hazman Bin Kamaruzaman, Nurul Jannah Binti Ambak","doi":"10.15605/jafes.040.01.13","DOIUrl":"10.15605/jafes.040.01.13","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to study the prevalence of hypophosphatemia and its associated risk factors in Diabetic Ketoacidosis (DKA) patients in the pediatric population.</p><p><strong>Methodology: </strong>We included 65 subjects aged 7 months to 18 years old who were admitted to Hospital Universiti Sains Malaysia (HUSM) for DKA. Patients' socio-demographic and clinical characteristics, and biochemical examinations from their first admission for DKA were analyzed. The diagnosis of DKA was based on the International Society for Pediatric and Adolescent Diabetes (ISPAD) criteria. Multiple logistic regression models examined associations between different variables and hypophosphatemia.</p><p><strong>Result: </strong>The prevalence of hypophosphatemia in DKA was highest on day 1, at 70.8%, with a mean age of 11 on presentation. Multiple logistic regression analysis showed plasma bicarbonate at day 3 [adjusted odds ratio (OR) 1.2, with a p-value of 0.027] and baseline hemoglobin [adjusted OR 0.62, with p-value 0.009] were significantly associated with hypophosphatemia during DKA.</p><p><strong>Conclusion: </strong>The prevalence of hypophosphatemia in DKA pediatric patients admitted to our center was highest on day 1 of admission. There were many factors associated with hypophosphatemia from simple logistic regression analysis. However, our final model revealed that plasma bicarbonate on day 3 and baseline Hb were the only significant risk factors for hypophosphatemia in DKA patients in the pediatric population.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"20-25"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lymphocytic Hypophysitis Presenting as Acute-onset Arginine Vasopressin Deficiency and Pituitary Stalk Thickening: A Case Report.","authors":"Lian Zi Yang, Shanty Velaiutham","doi":"10.15605/jafes.040.01.08","DOIUrl":"10.15605/jafes.040.01.08","url":null,"abstract":"<p><p>Lymphocytic hypophysitis (LHy) is a rare autoimmune inflammatory process that selectively affects the neurohypophysis and infundibulum, typically presenting with arginine vasopressin deficiency (AVP-D). On magnetic resonance imaging (MRI) with contrast, there is a thickening of the pituitary stalk, enlargement of the neurohypophysis or both with homogeneous enhancement. LHy can be self-limiting and regression can be seen radiologically during follow-up. A 22-year-old male presented with clinical findings consistent with AVP-D in 2016. MRI brain demonstrated enlargement of the pituitary stalk and absence of a posterior pituitary bright spot. He was given a trial of glucocorticoid treatment. His serial MRI brain showed a reduction of the pituitary stalk, but the AVP-D persisted. He was diagnosed with LHy. LHy is characterized by lymphocytic infiltration, leading to eventual destruction of the pituitary tissue accompanied by varying degrees of pituitary dysfunction. Definite diagnosis can only be established via pituitary stalk biopsy. Due to the wide range of possible aetiologies, close monitoring is strongly recommended for the treatment of presumed cases lacking histopathologic confirmation. The response rate to glucocorticoids has been variable. Periodic monitoring of anterior pituitary function and pituitary MRI are essential in the management of this condition.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"121-125"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nur Shahirah Mohamed Yasin, Tuan Mazlelaa Tuan Mahmood, Ernieda Hatah, Haniz Aqilah Hazaidi, Nur Amalina Mohd Zainal Abidin
{"title":"Tailoring Educational Content for T2DM Patients: A Qualitative Study on Preferences for Interactive Multimedia Applications.","authors":"Nur Shahirah Mohamed Yasin, Tuan Mazlelaa Tuan Mahmood, Ernieda Hatah, Haniz Aqilah Hazaidi, Nur Amalina Mohd Zainal Abidin","doi":"10.15605/jafes.040.01.18","DOIUrl":"10.15605/jafes.040.01.18","url":null,"abstract":"<p><strong>Background: </strong>The development of interactive multimedia-based applications has become increasingly important in providing effective health education to Type 2 Diabetes Mellitus (T2DM) patients. Understanding the educational content required for such applications from local patients' perspectives is crucial for designing a user-friendly and impactful tool for T2DM management.</p><p><strong>Objective: </strong>This study aims to investigate patients' views and preferences on the educational content and features of an interactive multimedia-based application for T2DM patients.</p><p><strong>Methodology: </strong>Semi-structured qualitative interviews were carried out with a sample of T2DM outpatients (n = 16) at a tertiary referral university hospital in Kuala Lumpur between October 2022 and January 2023. The interviews were recorded, transcribed and subjected to thematic analysis.</p><p><strong>Result: </strong>The majority of participants had been diagnosed with T2DM for less than ten years. The thematic analysis identified several key aspects related to the educational content required for development of a multimedia-based application. These include preference for educational materials, essential contents and interactive features. The participants also proposed a discussion area within such applications that would allow them to communicate and receive immediate advice from healthcare professionals, thus eliminating the need for frequent hospital visits.</p><p><strong>Conclusion: </strong>The findings of this study highlight the significance of interactive multimedia-based applications in providing health education for T2DM patients. The identified essential content areas from the patients' perspectives can inform the development of effective tailored educational materials for patient's benefit.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"45-52"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shahzad Sarwar, Gary Leong, Anthony Liu, Habib Bhurawala
{"title":"The Incidence and Severity of Paediatric Diabetic Ketoacidosis Presenting to a Metropolitan Hospital in Western Sydney: A 10-Year Retrospective Review.","authors":"Shahzad Sarwar, Gary Leong, Anthony Liu, Habib Bhurawala","doi":"10.15605/jafes.040.01.02","DOIUrl":"10.15605/jafes.040.01.02","url":null,"abstract":"<p><strong>Objectives: </strong>To report the incidence and clinical characteristics of paediatric patients presenting with diabetic ketoacidosis to the Emergency Department (ED) with new and pre-existing type 1 diabetes mellitus (T1DM).</p><p><strong>Methodology: </strong>A ten-year retrospective data analysis was performed on children under 16 years presenting to the ED with T1DM from January 2010. Demographic and laboratory data were extracted to determine the rates of DKA. Comparative statistics were performed between age groups and pre-existing and newly diagnosed T1DM patients.</p><p><strong>Results: </strong>A total of 196 children with T1DM were included. The mean age of the cohort was 9.3 ± 4.0 years, with female predominance (54%, <i>p</i> = 0.38). Most (60%) were newly diagnosed with T1DM, of which 38% presented in DKA. Amongst the total cohort, 43% presented in DKA.The older children accounted for 50% of the DKA presentations in the newly diagnosed cohort. Amongst the younger age group, 42% presented with severe DKA. There were higher rates of T1DM in areas of relative socioeconomic advantage.</p><p><strong>Conclusion: </strong>Children with T1DM presented with unacceptably high rates of DKA and posed a significant medical, psychosocial and financial burden on families and medical services. These findings suggest that a prospective public health campaign to reduce rates of DKA is warranted.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"14-19"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}