The Journal of Clinical and Scientific Research最新文献_第4页

A physician’s training: new challenges 医生的培训:新的挑战

The Journal of Clinical and Scientific Research Pub Date : 2014-10-01 DOI: 10.15380/2277-5706.JCSR.14.063

Valiathan Ms

引用次数: 0

Non-fasting samples for estimation of serum lipid levels in patients with coronary artery disease 非空腹样本用于估计冠心病患者的血脂水平

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.13.049

P. Srilakshmi, M. Gopinath, M. Bhaskar, K. Rambabu, G. Reddy

{"title":"Non-fasting samples for estimation of serum lipid levels in patients with coronary artery disease","authors":"P. Srilakshmi, M. Gopinath, M. Bhaskar, K. Rambabu, G. Reddy","doi":"10.15380/2277-5706.JCSR.13.049","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.13.049","url":null,"abstract":"Background: Evaluation of dyslipidaemia requiring fasting serum sample may not be possible in patients hospitalized in the acute phase. Evaluation of lipids in non-fasting sample was found to be useful but there are not many reports from India. Methods: One hundred and forty five patients with coronary artery disease (CAD) patients grouped as stable angina (SA), unstable angina (UA) and myocardial infarction (MI) and 66 healthy subjects were studied. Total serum cholesterol, triglycerides (TG), high-density lipoprotein cholesterol (HDL) and non-HDL were estimated in a non-fasting serum sample. Results: Increase in total serum cholesterol, TG, non-HDL along with a decrease in HDL levels was observed in CAD patients. The same trend was observed across the spectrum of CAD (SA, UA and MI). Conclusions: Non-fasting sample can also be utilized in order to evaluate CAD patients hospitalized in the acute phase where waiting for obtaining a fasting sample may delay institution of specific treatement. Srilakshmi P, Gopinath MF, Vijaya Bhaskar M, Rambabu K, Reddy GS. Non-fasting samples for estimation of serum lipid levels in patients with coronary artery disease. J Clin Sci Res 2014;3:206-209. Non fasting lipids Srilakshmi et al","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129059562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Clinical profile of sickle cell syndromes: experience at a tertiary care centre in South India 镰状细胞综合征的临床概况:在印度南部三级保健中心的经验

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.13.056

N. Chandra, A. Prasad, T. Reddy, M. Shetty, M. Subbalaxmi, Y. Raju

引用次数: 0

Scrub typhus with typical cutaneous lesion 伴有典型皮肤病变的恙虫病

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.13.059

Sridhar Ms, S. Jahangeer

引用次数: 0

A retrospective study of the functional outcome of schizophrenia depending on premorbid personality at the time of diagnosis 精神分裂症在诊断时取决于病前人格的功能结局的回顾性研究

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.14.030

D. Aruna, Sudhakar Tp

引用次数: 1

Antimicrobial resistance - have we scored a self goal? 抗菌素耐药性——我们是否实现了自我目标?

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.14.044

G. Ahluwalia

引用次数: 0

Comparison of intubating conditions and haemodynamic responses during rapid tracheal intubation using either suxamethonium or rocuronium with ephedrine pretreatment 麻黄碱预处理下苏沙霉素或罗库溴铵快速气管插管时的插管条件和血流动力学反应的比较

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.13.030

M. Madhusudan, M. Rao, AKrishna Simha Reddy, Vinay Kadiyala, A. Samantaray, N. Hemanth, Keerthi Charupalli

{"title":"Comparison of intubating conditions and haemodynamic responses during rapid tracheal intubation using either suxamethonium or rocuronium with ephedrine pretreatment","authors":"M. Madhusudan, M. Rao, AKrishna Simha Reddy, Vinay Kadiyala, A. Samantaray, N. Hemanth, Keerthi Charupalli","doi":"10.15380/2277-5706.JCSR.13.030","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.13.030","url":null,"abstract":"Background: Suxamethonium is considered as the “gold standard” for tracheal intubation. Because of innumerable contraindications for the use of this drug, there is a continuous search for other alternatives. Methods: In a prospective, randomized and double-blind study, we compared the intubating conditions and haemodynamic responses during rapid tracheal intubation using either suxamethonium or rocuronium with ephedrine pretreatment. We recruited 50 patients and allocated them into 2 groups (n= 25 each); Group S: received suxamethonium 1.5 mg/kg and Group R: received rocuronium 0.6 mg/ kg with ephedrine 100 μg/kg pretreatment. All patients were induced with 2 mg/kg propofol and intubation was attempted at 60 seconds. Haemodynamic responses and quality of intubating conditions were assessed. Results: Both groups were comparable in respect to age, sex, weight, Mallampati grade, Cormack Lehane grade and duration of laryngoscopy. Although both groups had clinically acceptable intubating conditions (good and excellent), there were more number of patients with better intubation score in Group S compared to Group R (p = 0.014). Conclusion: Suxamethonium still continues to be the “gold standard” for providing ideal tracheal intubation conditions. However, in conditions where suxamethonium is contraindicated, rocuronium-ephedrine combination can be used as an alternative to intubate the trachea at 60 seconds.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114341727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Giant angiomyolipoma with Wunderlich’s syndrome in a patient with tuberous sclerosis 结节性硬化症患者的巨血管平滑肌脂肪瘤伴Wunderlich综合征

The Journal of Clinical and Scientific Research Pub Date : 2014-07-01 DOI: 10.15380/2277-5706.JCSR.13.039

A. Tyagi, C. Reddy, N. Kumar, A. Reddy, A. Ganesh, K. Radhika

引用次数: 0

Prevalence of thyroid disorders and metabolic syndrome in adult patients with rheumatoid arthritis 成人类风湿关节炎患者甲状腺功能紊乱和代谢综合征的患病率

The Journal of Clinical and Scientific Research Pub Date : 2014-04-01 DOI: 10.15380/2277-5706.JCSR.14.005

B. Kumar, G. Naik, A. Mohan, D. Kumar, V. Suresh, K. Sarma, P. Rao, D. Katyarmal

{"title":"Prevalence of thyroid disorders and metabolic syndrome in adult patients with rheumatoid arthritis","authors":"B. Kumar, G. Naik, A. Mohan, D. Kumar, V. Suresh, K. Sarma, P. Rao, D. Katyarmal","doi":"10.15380/2277-5706.JCSR.14.005","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.14.005","url":null,"abstract":"Background: The clinical association between rheumatoid arthritis (RA) and hypothyroidism is important as both these conditions are associated with metabolic syndrome (MetS) which in turn makes the patients more prone for cardiovascular disease. Material and methods: In this cross-sectional study, the prevalence of thyroid disorders and MetS were studied in 54 consecutive adult patients with RA (mean age 46.0±10.4 years; 48 females) and 54 age and gender-matched healthy control subjects. Results: The prevalence of thyroid disorders was higher in patients with RA than in control subjects; however, this difference was not statistically significant [19/54 (35.2%) Vs 12/54 (22.2%); p=0.201]. Nine patients with RA already known to have hypothyroidism were receiving levothyroxine treatment. Among the remaining RA patients (n=45), a significantly higher prevalence of autoimmune thyroid disease (AITD) (10/45 Vs 4/54; 2=4.437, p=0.045) and subclinical hypothyroidism with anti-thyroid peroxidase (anti-TPO) antibody positivity (4/45 Vs 0/54; 2=5.002, p=0.040) were observed compared with healthy control subjects. The prevalence of MetS was higher in patients with RA than in control subjects; however, this difference was not statistically significant [31/54 (57.4%) Vs 25/54 (46.3%); p=0.336]. Conclusions: A significantly higher prevalence of AITD and subclinical hypothyroidism with anti-TPO antibody positivity in patients with RA suggests that these patients would benefit from screening for AITD. The co-existence of hypothyroidism and RA reiterates the need for monitoring and early identification of cardiovascular risk factors in patients with RA.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121055843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Study of three different fractionation regimens in palliative radiotherapy for painful bone metastases 疼痛性骨转移瘤姑息性放疗中三种不同分割方案的研究

The Journal of Clinical and Scientific Research Pub Date : 2014-04-01 DOI: 10.15380/2277-5706.JCSR.13.025

S. Jilla, S. Ratnam, K. Naidu, I. Monica, M. Ranadheer, P. Suresh

{"title":"Study of three different fractionation regimens in palliative radiotherapy for painful bone metastases","authors":"S. Jilla, S. Ratnam, K. Naidu, I. Monica, M. Ranadheer, P. Suresh","doi":"10.15380/2277-5706.JCSR.13.025","DOIUrl":"https://doi.org/10.15380/2277-5706.JCSR.13.025","url":null,"abstract":"Background: To assess the efficacy of single fraction with two different multi-fractionated radiotherapy regimens in treatment of painful bone metastases. Methods: Patients with painful bone metastases were randomly assigned to receive: Arm A: 8 Gray (Gy) in single fraction (n=15), Arm B: 20 Gy in 5 fractions at the rate of 4 Gy per fraction (n=15) and Arm C: 30 Gy in 10 fractions at the rate of 3 Gy per fraction (n=15). The arms were compared in terms of pain relief, performance improvement, analgesic requirement and duration of overall response at 1week, 1month, and 3 months after treatment. Results: Pain relief in Arms A, B and C at 1 week were 60%, 53.3% and 60%; at 1 month were 71.4%, 73.3%, 73.3%, at 3 months were 78.5%, 80% and 80% respectively. Performance improvement in Arm A, B and C at 1 week 60%, at 1 month 65%, 66% and 66%, at 3 months 78.5% ,80% and 80% respectively. Duration of overall response in all the patients who improved after therapy is 3 months There was no statistically significant difference between three arms with respect to pain relief, performance improvement, analgesic requirement and duration of overall response. Conclusions: The 8 Gy Single fraction is as efficacious as multi-fractionated regimens. Moreover, it is less expensive, decreases duration of hospital stay so single fraction can be used as an effective palliation method. Jilla S, Ratnam SV, Naidu KVJR, Monica I, Ranadheer M, Suresh P. Study of three different fractionation regimens in palliative radiotherapy for painful bone metastases. J Clin Sci Res 2014;3:90-6. DOI: http://dx.doi.org/10.15380/22775706.JCSR.13.025. Received: 28 May, 2013. Corresponding author: Dr Swapna Jilla, Assistant Professor, Department of Radiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India. e-mail: swapnaranadheer@gmail.com Three different fractionation regimens for bone metastates Jilla et al","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125257822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1