非空腹样本用于估计冠心病患者的血脂水平

P. Srilakshmi, M. Gopinath, M. Bhaskar, K. Rambabu, G. Reddy
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引用次数: 1

摘要

背景:在急性期住院的患者中,需要空腹血清样本来评估血脂异常可能是不可能的。在非空腹样本中评估脂质被发现是有用的,但来自印度的报道不多。方法:选取稳定期心绞痛(SA)、不稳定性心绞痛(UA)、心肌梗死(MI)三组冠心病(CAD)患者145例,并对66例健康者进行研究。在非空腹血清样本中评估血清总胆固醇、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL)和非HDL。结果:冠心病患者血清总胆固醇、TG、非高密度脂蛋白水平升高,高密度脂蛋白水平降低。在CAD (SA, UA和MI)频谱中观察到相同的趋势。结论:非空腹样本也可用于评估急性期住院的冠心病患者,等待获得空腹样本可能会延误特异性治疗的实施。Srilakshmi P, Gopinath MF, Vijaya Bhaskar M, Rambabu K, Reddy GS。非空腹样本用于估计冠心病患者的血脂水平。中华临床医学杂志,2014;3(3):391 - 391。非空腹血脂Srilakshmi等
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Non-fasting samples for estimation of serum lipid levels in patients with coronary artery disease
Background: Evaluation of dyslipidaemia requiring fasting serum sample may not be possible in patients hospitalized in the acute phase. Evaluation of lipids in non-fasting sample was found to be useful but there are not many reports from India. Methods: One hundred and forty five patients with coronary artery disease (CAD) patients grouped as stable angina (SA), unstable angina (UA) and myocardial infarction (MI) and 66 healthy subjects were studied. Total serum cholesterol, triglycerides (TG), high-density lipoprotein cholesterol (HDL) and non-HDL were estimated in a non-fasting serum sample. Results: Increase in total serum cholesterol, TG, non-HDL along with a decrease in HDL levels was observed in CAD patients. The same trend was observed across the spectrum of CAD (SA, UA and MI). Conclusions: Non-fasting sample can also be utilized in order to evaluate CAD patients hospitalized in the acute phase where waiting for obtaining a fasting sample may delay institution of specific treatement. Srilakshmi P, Gopinath MF, Vijaya Bhaskar M, Rambabu K, Reddy GS. Non-fasting samples for estimation of serum lipid levels in patients with coronary artery disease. J Clin Sci Res 2014;3:206-209. Non fasting lipids Srilakshmi et al
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