Nano Today最新文献

{"title":"Repurposing ferumoxytol as a nanowarming agent for vitrification-based organ preservation","authors":"Haikao Feng ,&nbsp;Yu Mao ,&nbsp;Yaolong Zhang ,&nbsp;Guangxiang Si ,&nbsp;Kun Lu ,&nbsp;Ming Zheng ,&nbsp;Weijie Ni ,&nbsp;Yan Li ,&nbsp;Yingyu Huang ,&nbsp;Miao Zhang ,&nbsp;Ning Gu","doi":"10.1016/j.nantod.2026.102981","DOIUrl":"10.1016/j.nantod.2026.102981","url":null,"abstract":"<div><div>Organ vitrification, a cryopreservation technique achieved by vascular perfusion of cryoprotective agents (CPAs) and rapid cooling to a stable glass-like state, enables long-term organ preservation in cryogenic state. However, rewarming vitrified organs to a transplantable state remains a major challenge, as it requires rapid and uniform heating to prevent ice recrystallization and mechanical cracking. Nanowarming, which exploits the heat-generating properties of iron oxide nanoparticles (IONPs) under an alternating magnetic field (AMF), has been shown to enable successful recovery of vitrified organs through vascular perfusion and AMF-induced homogeneous warming. Yet, the potential use of clinically approved IONPs, such as Ferumoxytol, in nanowarming has not been investigated. Here, we report pivotal studies on the vitrification and nanowarming of rat kidneys using Ferumoxytol. Our findings demonstrate that Ferumoxytol remains highly stable in CPAs, enables a ∼10-fold faster warming rate (∼79.9 °C/min) than the cooling rate (∼8.0 °C/min), and produces uniform warming kinetics across the cortex, medulla, and hilum of rat kidneys. Importantly, vitrified kidneys recovered by Ferumoxytol-based nanowarming exhibited comparable viability to both fresh controls and static cold stored kidneys, as assessed by renal pathology and vascular endothelium staining. Given its established clinical use as an iron supplement and MRI contrast agent, Ferumoxytol may serve as a readily translatable nanowarming agent, potentially accelerating the clinical adoption of organ vitrification and nanowarming.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102981"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145972872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanomedicine strategies for enhancing calcium overload in cancer therapy: A focus on regulating cellular function","authors":"Jingyu Li ,&nbsp;Dan Shi ,&nbsp;Bin Wang ,&nbsp;Mengru Li ,&nbsp;Qiwei Tian ,&nbsp;Wei Wei","doi":"10.1016/j.nantod.2025.102927","DOIUrl":"10.1016/j.nantod.2025.102927","url":null,"abstract":"<div><div>Calcium(Ca²⁺) overload, defined by excessive intracellular calcium levels that trigger apoptosis or necrosis—particularly in tumor cells—has emerged as a promising ion interference strategy in cancer therapy. However, tumor cells often evade apoptosis through the regulation of calcium channels and transporters, limiting the effectiveness of conventional Ca²⁺ delivery methods. To address this, nanomedicine-based strategies combined with cell function regulation have been developed to disrupt Ca²⁺ homeostasis in tumor cells by increasing Ca²⁺ influx or inhibiting efflux. These strategies employ nanomedicine to increase extracellular calcium concentration([Ca²⁺]ext), open calcium channels, or inhibit calcium efflux via specific channel and transporter blockers, leading to sustained elevation of the intracellular calcium concentration([Ca²⁺]int). This review systematically examines Ca²⁺ regulatory mechanisms in tumor cells and evaluates diverse strategies to amplify the therapeutic potential of Ca²⁺ overload. Through this analysis, we offer insights for advancing the development of Ca²⁺ overload as a targeted approach in cancer treatment.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102927"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifouling zwitterionic coating enhances electrochemical aptamer-based sensors for therapeutic drug monitoring","authors":"Haowei Duan ,&nbsp;Shuhua Peng ,&nbsp;Shuai He ,&nbsp;Shi-Yang Tang ,&nbsp;Keisuke Goda ,&nbsp;Chun H. Wang ,&nbsp;Ming Li","doi":"10.1016/j.nantod.2025.102892","DOIUrl":"10.1016/j.nantod.2025.102892","url":null,"abstract":"<div><div>Electrochemical aptamer-based (E-AB) sensors have experienced remarkable growth across a broad range of applications, such as precision medicine, chronic disease management, food safety, and environmental monitoring, due to their exceptional capability for real-time and continuous monitoring of biomarkers. However, biofouling in complex biological environments remains a critical challenge for the E-AB sensors, compromising signal strength, operational stability, and biosensing specificity. Here, we present a zwitterionic coating strategy that integrates poly-sulfobetaine methacrylate (SBMA) and polydopamine (PDA) to enhance the antifouling properties of the E-AB sensors, thereby enabling sensitive, stable, and accurate detection of a model antibiotic drug, vancomycin. The durable and hydrophilic antifouling layer was grafted onto the electrode surface to minimize signal drift while preserving sufficient signal on the E-AB sensors. The SBMA@PDA coating was systematically optimized and demonstrated superior resistance to biofouling under various environmental conditions, including pH, temperature, and mechanical stress. Furthermore, the coating was incorporated into a wearable microneedle patch for monitoring vancomycin dynamics in artificial interstitial fluids, achieving robust stability and performance. These findings establish a reliable and effective antifouling approach, advancing the practical application of E-AB sensors for continuous therapeutic drug monitoring in clinical and wearable healthcare settings.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102892"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct immunological features of Ferritin and AP205 nanovaccines lead to differing therapeutic outcomes against chronic hepatitis B","authors":"Xiaoxiao Zhou ,&nbsp;Wenjun Wang ,&nbsp;Yiyuan Zheng ,&nbsp;Jiyu Ding ,&nbsp;Mingzhao Zhu","doi":"10.1016/j.nantod.2025.102909","DOIUrl":"10.1016/j.nantod.2025.102909","url":null,"abstract":"<div><div>Ferritin and AP205 are two well-established representative nanoparticle platforms widely used in vaccine development. However, their immunological properties, vaccine efficacy, and underlying mechanisms remain incompletely characterized. In this study, we systematically compared the immune profiles of Ferritin- and AP205-based nanovaccines, explored their mechanisms of action, and evaluated their efficiency in the AAV-HBV infection mouse model. Our results demonstrated that the AP205 vaccine, which incorporates intrinsic ssRNA as a built-in adjuvant, elicited a stronger antibody response with a balanced IgG1/IgG2c profile. In contrast, the Ferritin vaccine supplemented with extrinsic CpG adjuvant induced an IgG1-biased antibody response. At the T cell level, the AP205 vaccine promoted a more mature germinal center T follicular helper (GC-Tfh) cell response, whereas the Ferritin+CpG vaccine stimulated a stronger Th1 response, likely due to enhanced dendritic cell activation by CpG. We further showed that codelivery of antigen and adjuvant is necessary and sufficient to augment IgG2c response for both platforms. Functionally, although the AP205-preS1 vaccine exhibited superior preventive efficacy against acute AAV-HBV infection compared to the Ferritin-preS1 +CpG vaccine, it showed reduced therapeutic efficacy against chronic AAV-HBV infection, highlighting the importance of Th1 immunity in viral clearance. Together, these findings suggest that the AP205 platform may serve as an effective platform for prophylactic vaccines, while Ferritin+CpG may hold greater potential for therapeutic applications requiring strong Th1 responses, such as chronic hepatitis B (CHB).</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102909"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145217727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Copper-doxorubicin nanodot-based dual catalytic metal prodrug liposome for enhanced chemotherapy and Chemodynamic Combination Therapychemodynamic combination therapy","authors":"Chuanyong Fan ,&nbsp;Yao Zhou ,&nbsp;Yihua Mei,&nbsp;Kaifang Wu,&nbsp;Meng Wang,&nbsp;Limeng Chen,&nbsp;Hongyan Liu,&nbsp;Zehao Dong,&nbsp;Lu Xu","doi":"10.1016/j.nantod.2025.102935","DOIUrl":"10.1016/j.nantod.2025.102935","url":null,"abstract":"<div><div>Although metal-based antitumor agents have for long been crucial components of most chemotherapy regimens, the majority of contemporary antitumor drugs have exhibited limited tumor selectivity and considerable off-target toxicity, restricting their therapeutic efficacy. Herein, metal prodrug nanodots (CD) comprising Cu^2 + and Doxorubicin (DOX) were first synthesized via coordination interaction. They were then co-loaded with Dihydroartemisinin (DHA) in a liposome nano-delivery system to enhance the metal drug’s selectivity and antitumor activity. The CD nanodots exhibited dual sensitivity to acid and Glutathione (GSH), which in turn, facilitated efficient tumor-specific drug release. Furthermore, the released Cu²⁺ could catalyze the endogenous H₂O₂ and loaded DHA, producing numerous toxic free radicals, which, in turn, induced lipid peroxidation and facilitated a synergistic antitumor effect of both Chemodynamic Therapy (CDT) and conventional chemotherapy. At the same time, Cu²⁺ decreased the GSH-mediated scavenging effect on the produced Reactive Oxygen Species (ROS) via a redox reaction, further enhancing the lethal effect of ROS on tumor cells. Given its potential clinical utility, this metal prodrug strategy could be leveraged for a safe and effective treatment of tumors.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102935"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineered nanovesicles amplify the crosstalk between neurogenesis and angiogenesis for pro-regenerative niche construction","authors":"Chengheng Wu ,&nbsp;Zhihong Chen ,&nbsp;Jialu Li ,&nbsp;Rong Li ,&nbsp;Wei Zhang ,&nbsp;Yusheng Zhang ,&nbsp;Gaowei Li ,&nbsp;Peng Liu ,&nbsp;Fuheng Hu ,&nbsp;Kunlun Ding ,&nbsp;Jie Ding ,&nbsp;Dan Wei ,&nbsp;Jing Sun ,&nbsp;Xiaoyin Liu ,&nbsp;Liangxue Zhou ,&nbsp;Hongsong Fan","doi":"10.1016/j.nantod.2025.102932","DOIUrl":"10.1016/j.nantod.2025.102932","url":null,"abstract":"<div><div>Nano-structured derivatives of natural organisms are enabling advances in biomaterial design, offering an innovative strategy to endow materials with specific biofunctions. In the regeneration of nervous tissue, neurogenesis and angiogenesis are intricately linked processes, yet their crosstalk in therapeutic strategies remains underexplored. This study develops an approach to produce engineered nanovisicles by pre-conditioning neural stem cells (NSCs) with brain-derived neurotrophic factor (BDNF). Compared with naive NSC exosomes, BDNF-preconditioned NSC exosomes (BNE) exhibited presented altered miRNA profiles enriched in pathways regulating neurogenesis, angiogenesis, and inflammation. In vitro assays demonstrated that BNE significantly enhanced NSC migration, neuronal/oligodendrocytic differentiation, and neuronal maturation, while promoting human umbilical vein endothelial cell (HUVEC) migration, invasion, and angiogenesis. Critically, a coculture system confirmed bidirectional crosstalk between neurogenesis and angiogenesis, which was amplified by the BNE. In a rat traumatic brain injury (TBI) model, the BNE-laden hydrogel synergistically mitigated neuroinflammation, recruited endogenous neural stem/progenitor cells (NSPCs) to the lesion, enhanced their neuronal differentiation and maturation, and stimulated angiogenesis. This pro-regenerative microenvironment, facilitated by neurovascular crosstalk, led to significant neural network reconstruction, tissue restoration, and improved functional recovery. These findings establish BDNF-preconditioned NSC exosomes delivered via a biomimetic hydrogel as a potent platform for CNS repair, harnessing the critical crosstalk between neurogenesis and angiogenesis.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102932"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-labeled ultrasmall nanoparticle probe for long-term PET tracking and real-time quantitative analysis of transplanted T lymphocytes in situ based on bioorthogonal reaction","authors":"Yang Chen ,&nbsp;Wangxi Hai ,&nbsp;Xiao Bao ,&nbsp;Chuyi Liu ,&nbsp;Yang Yang ,&nbsp;Yuetan Chen ,&nbsp;Kang Sun ,&nbsp;Yunxuan Zhang ,&nbsp;Ningshuang Ye ,&nbsp;Sanyuan Shi ,&nbsp;Samuel Kesse ,&nbsp;Biao Li ,&nbsp;Yuhong Xu ,&nbsp;Jinliang Peng","doi":"10.1016/j.nantod.2025.102896","DOIUrl":"10.1016/j.nantod.2025.102896","url":null,"abstract":"<div><div>The real-time, accurate understanding of the biodistribution of transplanted therapeutic cells is critical for their development and application. Positron emission tomography (PET) imaging has the potential to realize the noninvasive and quantitative evaluation of the spatial-temporal distribution of transplanted cells due to its unlimited tissue-penetration depth and quantitative capabilities, but its utility is limited by various shortcomings of existing imaging strategies or probes, such as the short half-life of the commonly used radioisotope fluorine-18 (¹⁸F) and the interference of high nonspecific background signals to the exact localization and quantification of target cells. Here, we describe a new strategy for the long-term PET tracking and real-time quantitative analysis of transplanted cells based on a tetrazine-bearing, ¹⁸F-labeled ultrasmall rare-earth nanoparticle probe (Tz-[¹⁸F]NaGdF₄) capable of labeling trans-cyclooctene (TCO) pretagged T lymphocytes <em>via</em> a bioorthogonal reaction at any point after their transplantation. The ultrasmall Tz-[¹⁸F]NaGdF₄ is readily prepared and characterized by rapid renal clearance and low nonspecific accumulation in major organs. The specific reaction between the Tz-[¹⁸F]NaGdF₄ probe and pretagged cells under physiological conditions enabled the specific PET imaging of target cells with low background <em>in situ</em>, and the measured PET image-derived standardized uptake value linearly and positively correlated with the number of pretagged T lymphocytes retained in tissues, ensuring their accurate quantification based on real-time PET signals. Therefore, the bioorthogonal reaction-based Tz-[¹⁸F]NaGdF₄-PET represents a useful tool for the long-term tracking and real-time quantification of transplanted cells <em>in vivo</em>.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102896"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanotechnology for diagnosis and therapy of idiopathic pulmonary fibrosis: Recent advances and future perspectives","authors":"Chenyu Zhao ,&nbsp;Ao Xiao ,&nbsp;Chen Chen ,&nbsp;Wei Mu ,&nbsp;Wen-Yang Li ,&nbsp;Lingqian Chang","doi":"10.1016/j.nantod.2025.102889","DOIUrl":"10.1016/j.nantod.2025.102889","url":null,"abstract":"<div><div>Idiopathic pulmonary fibrosis (IPF) is a highly progressive interstitial lung disease characterized by alveolar epithelial cell damage, extracellular matrix deposition, and irreversible lung parenchymal scarring, ultimately leading to fatal respiratory failure. Early diagnosis and effective intervention of IPF are crucial for improving its prognosis and reducing mortality. Current diagnostic methods for early-stage IPF rely on high-resolution CT, histopathological examination, and multidisciplinary discussions. However, these approaches have significant limitations, including poor accuracy, invasiveness, and being time-consuming, which often delays therapeutic intervention. Furthermore, existing pharmacotherapy offer only limited efficacy in slowing disease progression due to the low bioavailability and limited delivery efficiency. To address these challenges in diagnostics and therapeutics, nanotechnology-mediated solutions have emerged as promising approaches. Contemporary advancement focuses on three domains: (1) development of functionalized nano-contrast agents, nanoprobe- and nanoparticle-based biosensor platforms for <em>in vivo</em> and <em>in vitro</em> precision diagnostics, (2) design of nanocarriers for inhalable drug delivery to enhance therapeutic efficacy, and (3) integrated nanoplatforms enabling simultaneous therapeutic delivery and real-time monitoring for targeted intervention. Overall, this review summarized recent advancements in nanotheranostic applications for the diagnosis and therapy of IPF. Moving forward, future research prioritize overcoming translational barriers to facilitate clinical implementation.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102889"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal-polyphenol networks-mediated Au-Pt nanoplatform for dual-mode LDI-MS and colorimetric diagnosis of urinary stones","authors":"Qi Sang ,&nbsp;Yinpeng Liu ,&nbsp;Yanyan Li ,&nbsp;Wanshan Liu ,&nbsp;Tong Hu ,&nbsp;Ruimin Wang ,&nbsp;Zhebin Du ,&nbsp;Yuning Wang ,&nbsp;Kun Qian","doi":"10.1016/j.nantod.2025.102965","DOIUrl":"10.1016/j.nantod.2025.102965","url":null,"abstract":"<div><div>Urinary stones (US) are common urological disease with a high incidence and a risk of comorbidities. An accurate and high-throughput strategy is greatly needed for US diagnosis. Herein, we designed metal-polyphenol networks mediated Au-Pt hybrid nanoparticles (AuMPN-Pt HNPs) and fabricated a dual-functional nanoplatform integrating LDI-MS analysis and colorimetric assay for US diagnosis and subtype classification. The AuMPN-Pt HNPs exhibited superior LDI-MS performance with high sensitivity (limit of detection (LOD) &lt; 2 µM) and good MS signal reproducibility (coefficients of variation (CVs) &lt; 10 %) for accurate detection of metabolites. Meanwhile, AuMPN-Pt HNPs presented excellent peroxidase (POD)-like activity, allowing for direct and rapid detection of uric acid (UA) assisted by uricase with a LOD of 9.43 µM. Using the AuMPN-Pt HNPs assisted LDI-MS platform, we successfully achieved non-invasive US diagnosis by metabolic profiling of urine samples from US patients and the healthy controls (HCs), as well as subtype discrimination of calcium oxalate stones (CaOx stones) from UA stones by combining analysis of metabolic fingerprints from serum and urine samples. The subtype discrimination results were further verified by colorimetric platform for serum UA level analysis. The dual-functional nanoplatform exhibited outstanding sensitivity and specificity, providing innovative insights into disease diagnosis and subtype differentiation.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102965"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145879987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Back Cover - Graphical abstract TOC/TOC in double column continued from OBC if required, otherwise blank page","authors":"","doi":"10.1016/S1748-0132(25)00313-5","DOIUrl":"10.1016/S1748-0132(25)00313-5","url":null,"abstract":"","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102941"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145681249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}