Nano Today最新文献

{"title":"Pure organic phosphorescent scintillator for glucose metabolism regulation-enhanced low-dose X-ray-induced photodynamic therapy","authors":"Xiaoyu Zhang ,&nbsp;Yating Wen ,&nbsp;Baojie Du ,&nbsp;Yating Huang ,&nbsp;Yunxiang Liu ,&nbsp;Rong Zhang ,&nbsp;Liping Li ,&nbsp;Ruiping Zhang","doi":"10.1016/j.nantod.2024.102548","DOIUrl":"10.1016/j.nantod.2024.102548","url":null,"abstract":"<div><div>X-ray-induced photodynamic therapy (X-PDT) leverages the penetration power of X-rays to generate reactive oxygen species (ROS) within deep tissues for cancer treatment, merging the benefits of both photodynamic therapy and radiotherapy. Traditional X-PDT, however, typically relies on inorganic scintillators containing heavy-metals to act as energy transducers, exciting nearby photosensitizers to produce singlet oxygen. Moreover, the hypoxia conditions prevalent in tumors can severely diminish the efficacy of X-PDT. Here, we report a metal-free, self-enhanced organic phosphorescent nanoscintillator (termed OPSG NPs) capable of efficiently generating singlet oxygen under low-dose X-ray irradiation, facilitated by glucose metabolism regulation. OPSG NPs are constructed through a self-assembly behavior driven by molecular interactions between an organic phosphorescent scintillator and a glucose transporter 1 (GLUT1) inhibitor. The OPSG NPs serve dual functions, acting as both scintillator and photosensitizer, which can be activated by direct X-ray irradiation. Additionally, they possess the ability to inhibit glucose supply and reduce oxygen consumption for tumor cell respiration. This strategy effectively alleviates the hypoxia within the tumor microenvironment and consequently enhances the therapeutic efficacy of X-PDT. Both in vitro and in vivo studies demonstrate the excellent antitumor X-PDT performance. This glucose metabolism regulation-enhanced low-dose X-PDT strategy paves the way for more efficient therapy against deep-seated tumors.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102548"},"PeriodicalIF":13.2,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encapsulated solid-liquid dual continuous pathways with low modulus and high thermal conductivity for dynamic target autonomous thermal management","authors":"Qingxia He,&nbsp;Mengmeng Qin,&nbsp;Heng Zhang,&nbsp;Shuo Wang,&nbsp;Wei Feng","doi":"10.1016/j.nantod.2024.102549","DOIUrl":"10.1016/j.nantod.2024.102549","url":null,"abstract":"<div><div>Materials that exhibit both high thermal conductivity and soft elasticity are essential for effective thermal management in complex dynamic environments. Additionally, these materials can serve as sensing layers to interact with external conditions. However, materials that possess high thermal conductivity often have a high modulus, which limits their soft elasticity. In this study, we introduce a novel solid-liquid dual-oriented pathway embedded in modified PDMS. This design incorporates continuous liquid metal pathways and vertically aligned graphene, allowing for the optimal utilization of their high thermal conductivity, low modulus, and excellent resilience. The resulting LM-VGA/mPDMS composites exhibit impressive thermal conductivity (κ_⊥ = 7.32 Wm^–1K⁻¹) alongside soft elasticity and a remarkably low elastic modulus of 71.14 kPa. The LM-VGA/mPDMS composite facilitates effective thermal management in both dynamic and static conditions. Furthermore, the LM-VGA/mPDMS composites function as non-contact, self-powered sensors capable of accurately detecting object positions and states, making them suitable for dynamic target autonomous thermal management.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102549"},"PeriodicalIF":13.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vivo MRI tracking of bone mesenchymal stem cell viability with a T1-T2 switchable contrast agent","authors":"Jincong Yan ,&nbsp;Zhongzhong Lu ,&nbsp;Mingsheng Xu ,&nbsp;Jihuan Liu ,&nbsp;Ye Zhang ,&nbsp;Yi Cao ,&nbsp;Renjun Pei","doi":"10.1016/j.nantod.2024.102551","DOIUrl":"10.1016/j.nantod.2024.102551","url":null,"abstract":"<div><div>The successful implementation of stem cell therapy requires the development of imaging techniques to track transplanted stem cells <em>in vivo</em> and monitor their fate over time. Most <em>in vivo</em> imaging methods focus on providing information about the distribution and migration of transplanted stem cells, while monitoring their viability-crucial for optimizing therapy-remains undeveloped. Although a few <em>in vivo</em> imaging techniques have been developed for assessing the viability of transplanted stem cells, their applicability is restricted by limited penetration depth. To address this, magnetic resonance imaging (MRI) that is collaboratively utilized with tailored contrast agents has been explored to track the viability of transplanted stem cells without this limitation. However, currently available MRI contrast agents struggle with low accuracy in monitoring viability due to poor controllability or minimal signal change in response to cell death. Here, we present an extremely small iron oxide nanoparticles (ESIONPs)-based T₁-T₂ switchable MRI contrast agent (ESIONPs-GSH) designed to accurately detect cell apoptosis in response to elevated reactive oxygen species (ROS).Specifically, ESIONPs-GSH was obtained by modifying the surface of ESIONPs with ROS-sensitive glutathione (GSH) and amphipathic 3-((3-aminopropyl) dimethylammonio) propane-1-sulfonate (ADPS) molecules. The results demonstrate that ESIONPs-GSH is biocompatible, with negligible effects on the proliferation and differentiation of bone mesenchymal stem cells (BMSCs) post-labeling. Additionally, BMSCs labeled with ESIONPs-GSH exhibit T₁ contrast; upon cell death, increasing cellular ROS oxidize GSH and induce cross-linking of ESIONPs-GSH, resulting in a switch to T₂ contrast. Benefiting from the significantly contrasting signal following the T₁-T₂ contrast switch, ESIONPs-GSH allows for accurate assessment of the survival of BMSCs transplanted into the axillary regions of mice through MRI monitoring. ESIONPs-GSH enabled MRI can effectively track transplanted stem cell viability <em>in vivo</em> without penetration depth limitations, making it a promising tool for guiding stem cell-based therapies.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102551"},"PeriodicalIF":13.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MXene - A frontier exploiter in carbon dioxide conversion: Synthesis and adsorption","authors":"Ting Yan ,&nbsp;L.C. Xu ,&nbsp;W.G. Pan ,&nbsp;L.W. Wang","doi":"10.1016/j.nantod.2024.102546","DOIUrl":"10.1016/j.nantod.2024.102546","url":null,"abstract":"<div><div>MXene, as a novel two-dimensional material, has garnered global attention due to its unique structure and outstanding physicochemical properties. MXene-based adsorption/catalytic agents, characterized by their high specific surface area, abundant surface functional groups, excellent conductivity, and tunability, are considered excellent materials for carbon dioxide (CO₂) adsorption and conversion. In recent years, the synthesis methods of MXene have evolved from the initial hydrofluoric acid (HF) etching to Lewis acid molten salt etching, significantly reducing the risks and pollution associated with the synthesis process while enhancing yield and performance. This review provides a comprehensive overview of the application of MXene materials in the adsorption and catalytic conversion of CO₂. It first outlines the development history of MXene. Subsequently, the synthesis methods of MXene are discussed, with particular emphasis on the advantages of fluorine-free synthesis methods, including relatively mild etching conditions, safety, pollution-free nature, and ease of control. Later, we elucidate its progress in CO₂ adsorption and conversion. Finally, the prospects of MXene materials in the field of CO₂ conversion are discussed, along with an exploration of the strengths and weaknesses of current synthesis methods. It has pointed out that MXene holds significant potential in constructing a sustainable carbon cycle economy, underscoring its crucial role in sustainable development.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102546"},"PeriodicalIF":13.2,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging intelligent wearable devices for cardiovascular health monitoring","authors":"Yiqian Wang ,&nbsp;Yang Zou ,&nbsp;Zhou Li","doi":"10.1016/j.nantod.2024.102544","DOIUrl":"10.1016/j.nantod.2024.102544","url":null,"abstract":"<div><div>Cardiovascular diseases have long posed a significant threat to human health. Wearable devices are increasingly vital in cardiovascular health monitoring, disease screening, and early warning because of their non-invasiveness, real-time data provision and continuous monitoring capability. The collection, processing, and analysis of data in cardiovascular health monitoring involve numerous repetitive and standardized tasks, where artificial intelligence (AI) technology plays a pivotal role. AI is particularly effective in handling large volumes of data, thus enhancing the diagnostic and predictive capabilities of wearable devices. This review summarizes essential indicators for assessing cardiovascular health and provides a comprehensive introduction to commonly used non-invasive monitoring methods, including pulse pressure, photoplethysmography, electrocardiogram, bioimpedance analysis, seismocardiography/ ballistocardiography, and ultrasonography. Additionally, some impressive advances in wearable cardiovascular health monitoring technologies are reviewed and their integration with AI is highlighted, demonstrating typical application cases from recent years. Finally, the review discusses the current challenges of integrating AI into wearable devices for cardiovascular health monitoring, focusing on aspects from device design, algorithm optimization, comfort, reliability, and security. With the seamless integration of AI and wearable devices, a new generation of wearable intelligent devices promises to revolutionize the monitoring, prevention and management strategies of cardiovascular diseases.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102544"},"PeriodicalIF":13.2,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanically matched and multistage hybrid porous scaffolds for stem cell-based osteochondral regeneration","authors":"Shao-Jie Wang ,&nbsp;Rong-Hui Deng ,&nbsp;Chang-Hui Song ,&nbsp;Fu-Zhen Yuan ,&nbsp;Peng-Qiang Li ,&nbsp;Xiao-Yan Cao ,&nbsp;Xing Wang ,&nbsp;Lin Lin ,&nbsp;Ji-Ying Zhang ,&nbsp;Yu-Fang Zhu ,&nbsp;Jia-Kuo Yu","doi":"10.1016/j.nantod.2024.102539","DOIUrl":"10.1016/j.nantod.2024.102539","url":null,"abstract":"<div><div>Osteochondral tissue has limited self-repair ability owing to its ischemic microenvironment and mechanically challenging conditions. Cell-based tissue engineering, a promising strategy for osteochondral regeneration, is influenced by the osteochondral-inducing scaffolds, such as bioactive agents and bionic microstructures, and mechanical properties. The current platforms are unsatisfactory because they fail to match the mechanical strength of natural osteochondral tissue while retaining high porosity and bioactivity. Hence, we developed growth factor-free multistage porous hybrid scaffolds composed of poly(lactic-<em>co</em>-glycolic acid) (PLGA) backbones with milli-micrometer two-stage pores and bioactive poly(γ-ethyl-<span>l</span>-glutamate) (PELG) thermo-responsive hydrogel. Highly porous pure PLGA backbones with controllable pore structures and tunable mechanical strength were prepared using low-temperature deposition modeling 3D printing and salt-leaching method with sodium chloride (NaCl) as a porogen. The arginine-glycine-aspartic acid (RGD) peptide and the chondrogenic molecule kartogenin (KGN) were conjugated to the terminals of poly(ethylene glycol) and PELG to enhance cell proliferation and induce cartilage differentiation, respectively. Moreover, the multistage PLGA/^RGDPELG_KGN porous hybrid scaffolds provided conducive environments for the proliferation and chondrogenesis of peripheral blood-derived mesenchymal stem cells (PBMSCs) and successfully repaired critical-sized osteochondral defects in the rabbit femoral trochlea, indicating its clinical potential for osteochondral repair.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102539"},"PeriodicalIF":13.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced glomerular transfection by BMP7 gene nanocarriers inhibits CKD and promotes SOX9-dependent tubule regeneration","authors":"Yifan Tai ,&nbsp;Zhen Liu ,&nbsp;Yanrong Wang ,&nbsp;Xinyan Zhang ,&nbsp;Ruifang Li ,&nbsp;Jiangyue Yu ,&nbsp;Yao Chen ,&nbsp;Lili Zhao ,&nbsp;Jia Li ,&nbsp;Xueyuan Bai ,&nbsp;Deling Kong ,&nbsp;Adam C. Midgley","doi":"10.1016/j.nantod.2024.102545","DOIUrl":"10.1016/j.nantod.2024.102545","url":null,"abstract":"<div><div>Renal fibrosis and loss of kidney function are key characteristics of chronic kidney disease (CKD). To address the lack of effective treatments, multifunctional layer-by-layer (LbL) assembled polymeric gene-carrier nanoparticles (PCHS-NP) are prepared to realize preferential accumulation and retention within renal glomerular cells, thereby effectively leveraging cortically localized structures for the synthesis and paracrine secretion of the antifibrotic growth factor, bone morphogenetic protein-7 (BMP7). PCHS-NP had stable homogenous morphologies, kidney-targeting functionality, antioxidative effects, and high transfection efficiency. In unilateral ureteral obstruction (UUO)-induced renal fibrosis, a single systemic injection of PCHS-NP prevents tubular atrophy and interstitial fibrosis, and the resultant tissue microenvironment is more conducive to tubular regeneration driven by the upregulation of proliferative SOX9-expressing tubular cells. In longer-term folic acid (FA)-induced renal fibrosis, we show that early, late, and repeat systemic injections restore kidney health and function. This study indicates that PCHS-NP accomplish a promising therapeutic option for the treatment of CKD.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102545"},"PeriodicalIF":13.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of strong metal-support interactions: Investigating Pt and Pt-based alloys on CdS nanorods through experimental and simulated approaches","authors":"Jiuyi Hu ,&nbsp;Jiayu Xu ,&nbsp;Ri Feng ,&nbsp;Shaohui Zheng ,&nbsp;Jiajia Li ,&nbsp;Zhicheng Zhang ,&nbsp;Wenjing Liu ,&nbsp;Faisal Saleem","doi":"10.1016/j.nantod.2024.102543","DOIUrl":"10.1016/j.nantod.2024.102543","url":null,"abstract":"<div><div>The catalytic performance of supported metal nanoparticles (NPs) is greatly affected by metal-support interaction (MSI). Understanding the mechanisms and dynamics of MSI in heterogeneous catalysis remains challenging. Traditionally, MSI studies have focused on metal oxide supports and rarely compared MSI between Pt and Pt-based alloys, despite the importance of Pt in catalysis. In this study, we introduce CdS nanorods as a novel support material and investigate the MSI behavior of both Pt and Pt-based alloy NPs using in situ TEM electron beam irradiation. Our findings show that Pt NPs have strong MSI with CdS and that encapsulation layers form over Pt NPs because Pt has the high surface energy. On the other hand, Pt-based alloys have weaker MSI. These experiments were validated by direct thermal annealing for four hours. Molecular dynamics simulations were used to explain the observed behavior, providing insights into how the surface energy differences between Pt and Pt-based alloys influence their interactions with CdS nanorods. These findings offer valuable insights into catalyst design, highlighting the potential for controlling MSI strength to optimize catalytic performance in heterogeneous systems.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102543"},"PeriodicalIF":13.2,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142573392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glucose-gated nanocoating endowing polyetheretherketone implants for enzymatic gas therapy to boost infectious diabetic osseointegration","authors":"Jiahe Li ,&nbsp;Menglin Fan ,&nbsp;Zheng Jiao ,&nbsp;Yau Kei Chan ,&nbsp;Lei Cheng ,&nbsp;Jiyao Li ,&nbsp;Yi Deng ,&nbsp;Kunneng Liang","doi":"10.1016/j.nantod.2024.102541","DOIUrl":"10.1016/j.nantod.2024.102541","url":null,"abstract":"<div><div>The hyperglycemic micromilieu surrounding implants in diabetic patients leads to high failure rate of implantation and implant-associated infection. Carbon monoxide (CO) has been reported to combat infections; however, its on-demand liberation and the elucidation of the underlying antibacterial mechanism remain challenging. To address this issue, we develop a multipurpose orthopedic implant comprising polyetheretherketone, glucose oxidase (GOx), and manganese carbonyl nanocrystals (MnCO), serving as a glucose-gated nanocoating for enzymatic gas therapy to improve infectious diabetic osseointegration. The GOx acts as a glucose-actuated gate responsive to hyperglycemia, thereby delivering CO <em>in situ</em> triggered by the GOx-driven Fenton-like reaction of MnCO nanocrystals. The released CO considerably prevents bacterial multiplication by penetrating the membrane, binding to cytochrome <em>bo</em>_<em>3</em>, and interfering with the respiratory chain <em>in vitro</em>. Furthermore, the engineered implant displays desired antibacterial properties and enhances osseointegration <em>in vivo</em>. Collectively, the orthopedic nanocoating implant is capable of delivering glucose-gated enzymatic gas therapy, promising for treating infectious diabetic bone defects.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102541"},"PeriodicalIF":13.2,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142560737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atomic scale in-situ observation of gas-solid interaction regulating the pre-nucleation process of Pd atomic clusters","authors":"Yuchen Zhu,&nbsp;Yinghui Sun,&nbsp;Zhitao Zhao,&nbsp;Yingying Xu,&nbsp;Hao Li,&nbsp;Rongming Wang","doi":"10.1016/j.nantod.2024.102533","DOIUrl":"10.1016/j.nantod.2024.102533","url":null,"abstract":"<div><div>Advancements in nanotechnology have propelled the understanding of atomic-scale nucleation processes, essential for the evolution of atomic manufacturing. The process of amorphous precursors nucleation showcases a complex transition influenced by various factors. Utilizing aberration-corrected ETEM and theoretical calculation, we explore the nucleation of amorphous Pd atomic clusters. This study examines the nucleation dynamics and gas-solid interaction regulating of Pd clusters on ultrathin carbon films, prepared via electron beam evaporation. HRTEM observation and FFT analysis reveal that, in the early stage of nucleation, Pd cluster growth predominantly follows an Ostwald ripening-like mechanism. Atoms from smaller clusters migrate and attach to larger ones, facilitating their progression to critical nucleation size. Environmental conditions significantly influence this process; hydrogen atmospheres lower the surface energy of Pd clusters, reducing the critical nucleation size, while argon atmospheres impede growth of Pd clusters by occupying migration sites on the carbon surface. These insights into atomic cluster behavior and environmental interactions are crucial for understanding the early stages of nucleation from amorphous to crystalline and can help opens new avenues for the controlled fabrication of materials with optimized functionalities.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"59 ","pages":"Article 102533"},"PeriodicalIF":13.2,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}