Methodist DeBakey cardiovascular journal最新文献_第3页

Methamphetamine's Devastating Scourge. 甲基苯丙胺的毁灭性灾难。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1568

Samra Iqbal, Justin C Cordova, James B Young

{"title":"Methamphetamine's Devastating Scourge.","authors":"Samra Iqbal, Justin C Cordova, James B Young","doi":"10.14797/mdcvj.1568","DOIUrl":"10.14797/mdcvj.1568","url":null,"abstract":"This edition of Poet's Pen focuses on a rare but catastrophic complication associated with methamphetamine, the use of which is progressively rising in certain parts of the country. The featured poem, \"The Pulse of a Silent Killer,\" shows the utility of poetry to sound the alarm amidst an emergency, alerting the medical community that all may not be as it seems. According to its author, the piece \"reflects the rising crisis of methamphetamine-induced cardiomyopathy among young adults in Texas. This devastating condition, often overlooked, strikes with increasing frequency, leaving young lives cut short and communities shattered. The poem captures the silent but powerful toll of the epidemic and offers both a mournful reflection on lives lost and a call to action for those in the medical field to rise to the challenge of prevention and care. The painful panoply of substance abuse is one that captures many, and methamphetamine is but one of several illicit drugs that have become attractive to use. It is highly addictive, being abused largely on account of the stimulant effects that seem to be uniquely attractive to younger users. Though the euphoric effects of methamphetamine are short-lived, its long-term implications-including the cardiomyopathy associated with its use-can be challenging to diagnose, difficult to treat, and quickly result in disastrously permanent consequences.","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"129-132"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CAD at the Intersection of Cardiology and Rheumatology: Focus on Cardiovascular Imaging. CAD在心脏病学和风湿病学的交叉点：关注心血管成像。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1646

Kenneth Wade Williams, Helene DiGregorio, Deepak Jagannath, Attila Feher

引用次数: 0

Temporary Mechanical Circulatory Support for Acute Myocardial Infarction Cardiogenic Shock. 急性心肌梗死心源性休克的临时机械循环支持。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1654

Saliha Erdem, Dhruvil Ashishkumar Patel, Karl Abou Zeid, Joe Aoun

引用次数: 0

Genetic Risk Score Enables a Vaccine for Early Primary Prevention of CAD. 遗传风险评分为CAD的早期一级预防提供了疫苗。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1617

Robert Roberts

{"title":"Genetic Risk Score Enables a Vaccine for Early Primary Prevention of CAD.","authors":"Robert Roberts","doi":"10.14797/mdcvj.1617","DOIUrl":"10.14797/mdcvj.1617","url":null,"abstract":"Early primary prevention of coronary artery disease (CAD) is limited by lack of biomarkers to detect CAD risk among young asymptomatic individuals. Although early prevention is more effective than secondary interventions, conventional risk factors such as hypertension usually do not appear until the fifth or sixth decade of life. Conversely, genetic risk, which accounts for 50% of all CAD risk, is randomly distributed at conception and does not change with age; therefore, it can be determined any time after birth using a genetic polygenic risk score (PRS). Genetic risk is markedly modified by lifestyle changes and, specifically, lowering levels of low-density lipoproteins (LDL). CAD risk depends on the concentration and duration of exposure to plasma LDL, which is estimated by the product of age times LDL (mg-years). The minimum threshold for a myocardial infarction (MI) in someone with a plasma LDL of 125 at age 40 is 5,000 mg-years. The goal of primary prevention is to delay reaching the minimal clinical threshold as long as possible. This review makes the case for a long-acting, lipid-lowering drug, administered annually starting at age 30, that could delay the threshold for MI until age 100.","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"101-112"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coronary Artery Disease: Contemporary Insights Across Physiology, Imaging, and Innovation. 冠状动脉疾病：跨越生理学、成像和创新的当代见解。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1673

Nadeen N Faza, Joe Aoun Md

引用次数: 0

Drug-Coated Balloons for Coronary Interventions: A Focused Review. 冠脉介入治疗药物包被气球：重点综述。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1607

Akash H Patel, Mark W Abdelnour, Antonio H Frangieh

{"title":"Drug-Coated Balloons for Coronary Interventions: A Focused Review.","authors":"Akash H Patel, Mark W Abdelnour, Antonio H Frangieh","doi":"10.14797/mdcvj.1607","DOIUrl":"10.14797/mdcvj.1607","url":null,"abstract":"The development of catheter-based interventions has revolutionized the treatment of coronary artery disease (CAD), from the first heart catheterization in 1929 to the emergence of drug-coated balloons (DCBs) as a treatment for in-stent restenosis (ISR). This review explores the evolution and clinical application of DCBs in CAD, with a particular focus on their role in managing ISR, de novo coronary disease, and complex lesions. DCBs deliver antiproliferative drugs such as paclitaxel or sirolimus to the vessel wall and have emerged as a promising alternative to traditional stent-based therapies, reducing the need for permanent metallic implants and associated thrombotic risks. Early research demonstrated the effectiveness of DCBs in ISR, and recent studies have expanded their application to small vessel disease, bifurcation lesions, and long diffuse lesions. Notably, DCBs have shown non-inferiority to drug-eluting stents in certain cases, including high-risk patients and those with complex coronary anatomy. Despite some challenges, such as the potential for coronary dissection and the need for optimal lesion preparation, DCBs have demonstrated strong potential in reducing restenosis and improving long-term outcomes in a variety of patient populations. While further studies are required to refine their use in off-label indications, DCBs may represent a versatile, effective, and safer approach in the management of CAD.","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"37-53"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coronary Artery Anomalies in Review: Anomalous Origin, Aneurysms, and Fistulae. 冠状动脉异常综述：异常起源、动脉瘤和瘘管。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1613

Jack A Hoover, Keshika Catakam, Rachel E Wittenberg, Jordan P Bloom, Doreen DeFaria Yeh, Q Joyce Han, Ada C Stefanescu Schmidt

引用次数: 0

French Impressions. 法国的印象。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1662

Philip Alexander

引用次数: 0

How Different is Invasive Coronary Physiology in the Left Anterior Descending Artery? 左前降支有创冠状动脉生理有何不同？

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1606

Nils P Johnson, K Lance Gould

引用次数: 0

Intravascular Ultrasound Imaging-Guided Percutaneous Coronary Intervention: Evidence and Practical Implications. 血管内超声成像引导的经皮冠状动脉介入治疗：证据和实际意义。

Methodist DeBakey cardiovascular journal Pub Date : 2025-08-12 eCollection Date: 2025-01-01 DOI: 10.14797/mdcvj.1611

Safi U Khan, Neal S Kleiman, Alpesh R Shah

引用次数: 0