{"title":"Diagnostic Enigma of Blurring Vision and Apparent Shock.","authors":"Muralidhar Naik, Ramachandran Padmakumar","doi":"10.14797/mdcvj.1491","DOIUrl":"10.14797/mdcvj.1491","url":null,"abstract":"<p><p>This interactive CME case poses the challenge of diagnosing a male patient in his late 60s who presented to the emergency department of a tertiary care hospital with neurological symptoms. He complained of transient blurred vision lasting for 20 minutes and was later identified to be in shock.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 1","pages":"90-95"},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12447791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Idiopathic Chylopericardium in an Adult Female.","authors":"Abdul Azeez Asad Mohammed, Hafsah Ali, Shaikh Swalehin Bux, Prashant Prabhakar, Abid Hussain, Waleed Dita","doi":"10.14797/mdcvj.1660","DOIUrl":"https://doi.org/10.14797/mdcvj.1660","url":null,"abstract":"<p><p>Chylopericardium (CP), defined as the accumulation of chyle in the pericardial cavity, is a rare condition, especially in the absence of an identifiable secondary cause. Primary idiopathic chylopericardium (PIC) is even more uncommon, with limited cases reported in the literature. We report the case of a 43-year-old South Asian woman who presented with palpitations and fatigue. Echocardiography revealed a large pericardial effusion with signs of cardiac tamponade, necessitating emergent pericardiocentesis. The pericardial fluid aspirated was pinkish and turbid, which turned to milky white after centrifugation. Analysis of the pericardial fluid demonstrated a high triglyceride concentration, lymphocytic predominance, and fat globules, consistent with chylous effusion. A thorough diagnostic workup-including infectious, rheumatologic, and oncologic evaluations-was unrevealing, confirming a diagnosis of PIC. Lymphoscintigraphy was misleading in this case, with no thoracic duct abnormalities reported. Following an initial response to conservative management with pericardiocentesis and a medium-chain triglyceride-rich diet, the patient experienced recurrence of symptoms and fluid reaccumulation. Definitive management via thoracic duct ligation and pericardial window surgery was performed, resulting in complete resolution of the effusion. At 6-month follow-up, the patient remained asymptomatic with no evidence of recurrence. This case highlights the importance of considering primary CP in the differential diagnosis of pericardial effusion. Absence of classical inflammatory signs and symptoms can be suggestive of chylous effusion. The report also supports surgical intervention as a definitive treatment even if lymphoscintigraphy does not reveal clear thoracic duct pathology.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 1","pages":"84-89"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sana Irshad, Parth Adrejiya, Mohammad Abubaker, James Whitaker
{"title":"Kommerell's Diverticulum Masquerading in a Right Aortic Arch: A Vascular Surprise.","authors":"Sana Irshad, Parth Adrejiya, Mohammad Abubaker, James Whitaker","doi":"10.14797/mdcvj.1641","DOIUrl":"https://doi.org/10.14797/mdcvj.1641","url":null,"abstract":"<p><p>Kommerell's diverticulum (KD) is a rare vascular anomaly characterized by aneurysmal dilation of the descending aorta at the origin of an aberrant subclavian artery, which can occur in either a right- or left-sided aortic arch. Aberrant right subclavian arteries are found in approximately 0.5% to 2% of the population while aberrant left subclavian arteries are less common, occurring in only 0.04% to 0.4%. KD is associated with aberrant subclavian arteries in 60% to 82% of cases. It is often identified incidentally during imaging studies performed for unrelated reasons, which contributes to the limited understanding of its natural progression. However, KD carries significant risks, including a 53% chance of aneurysm rupture and a 19% incidence of aortic dissection. As a result, surgical management is generally recommended. Although no standardized treatment exists, options include thoracic endovascular aortic repair, hybrid procedures, and open repair. Intervention is typically advised when the orifice diameter exceeds 3 cm and depth exceeds 5 cm due to elevated rupture risk. We present a case of incidentally detected KD originating from a right aortic arch with an aberrant left subclavian artery.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 1","pages":"81-83"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Salman Sabri, Lawrence Benedict, Dylan Souder, Lukas Kaugars, Kunal Patel, Babak Bozorgnia, Talha Nazir
{"title":"Lehigh Valley Procedure: Combined Pulmonary Vein Isolation and Accessory Pathway Ablation for Atrial Fibrillation in Wolff-Parkinson-White Syndrome.","authors":"Muhammad Salman Sabri, Lawrence Benedict, Dylan Souder, Lukas Kaugars, Kunal Patel, Babak Bozorgnia, Talha Nazir","doi":"10.14797/mdcvj.1618","DOIUrl":"https://doi.org/10.14797/mdcvj.1618","url":null,"abstract":"<p><p>Wolff-Parkinson-White (WPW) syndrome is a congenital condition characterized by the presence of an accessory pathway (AP) that can lead to tachyarrhythmias such as atrial fibrillation (AF). Patients with WPW are at an increased risk of developing AF, with a prevalence of up to 30%. Despite successful ablation of the AP, AF recurrence remains a challenge, particularly in older patients or those with a history of AF. Concomitant pulmonary vein isolation (PVI) may help reduce the risk of recurrence by targeting atrial remodeling and pulmonary vein involvement in AF. This case describes a 70-year-old male with WPW and AF who underwent a combined PVI and AP ablation procedure. The patient remained free of AF post-procedure, suggesting that this approach may be effective in high-risk patients. Further randomized controlled trials are necessary to evaluate the efficacy of this combined approach in reducing AF recurrence compared to AP ablation alone, especially in older patients.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 1","pages":"74-80"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikitha M Murthy, Thomas T Yoo, Alyssa Sanchez, Mayur Chhitu, Dmitry Abramov, Jason Gatling, Mamas A Mamas, Purvi Parwani
{"title":"Preoperative Diagnostic Assessment of Patients with Cardiovascular Risk Factors Undergoing Noncardiac Surgery: A 2025 Update.","authors":"Nikitha M Murthy, Thomas T Yoo, Alyssa Sanchez, Mayur Chhitu, Dmitry Abramov, Jason Gatling, Mamas A Mamas, Purvi Parwani","doi":"10.14797/mdcvj.1629","DOIUrl":"10.14797/mdcvj.1629","url":null,"abstract":"<p><p>Despite medical advances and increased perioperative testing, mortality and cardiovascular complications of noncardiac surgery (NCS) have hardly declined since the early 2000s. Studies demonstrate a disproportionate overutilization of preoperative diagnostic testing with a concurrent underutilization of interventions that have been shown to meaningfully modify mortality. Consequently, there has been a paradigm shift in the approach to perioperative testing. Current thinking advocates for a more judicious and individualized approach-that is, reserving noninvasive testing for select cases at highest risk of periprocedural cardiovascular events, where it may more effectively alter management. Thus, this review provides an update of the latest evidence-based recommendations on preoperative diagnostic assessment of patients with cardiovascular risk factors undergoing NCS, proposes a framework that can be referenced when approaching such a patient in clinical practice, and highlights areas that need more data to guide decision-making in clinical practice.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"87-100"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation-Induced Coronary Artery Disease.","authors":"Mohamad B Taha","doi":"10.14797/mdcvj.1661","DOIUrl":"10.14797/mdcvj.1661","url":null,"abstract":"<p><p>This <i>Points to Remember</i> column discusses radiation-induced coronary artery disease (RICAD), a distinct and increasingly recognized cause of CAD among cancer survivors after receiving chest radiation therapy. RICAD typically presents years or even decades after mediastinal radiation therapy, often affecting young patients without traditional cardiovascular risk factors. Unlike typical atherosclerosis, RICAD is driven by chronic inflammation and fibrosis. Clinicians should maintain a high index of suspicion in cancer survivors, and management often favors medical therapy and percutaneous coronary intervention when indicated.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"113-117"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kendi Burnette-Phelps, Lydia S Sohn, Anjali Bhardwaj, Vaibhav Sharma, Mangesh Kritya, Akshat Sahai, Shariq Shamim
{"title":"The Single Coronary Artery: A Rare Anatomic Variant.","authors":"Kendi Burnette-Phelps, Lydia S Sohn, Anjali Bhardwaj, Vaibhav Sharma, Mangesh Kritya, Akshat Sahai, Shariq Shamim","doi":"10.14797/mdcvj.1623","DOIUrl":"10.14797/mdcvj.1623","url":null,"abstract":"<p><p>We report the case of a 67-year-old female with heart failure and a reduced ejection fraction (25%). Angiography revealed that all of her major coronary vessels stemmed from a single ostium at the right aortic sinus.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"118-120"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiovascular Health During Menopause Transition: The Role of Traditional and Nontraditional Risk Factors.","authors":"Samuel Yousefzai, Zahir Amin, Huzaifa Faizan, Maheen Ali, Suha Soni, Michael Friedman, Abeera Kazmi, Faith Elise Metlock, Garima Sharma, Zulqarnain Javed","doi":"10.14797/mdcvj.1619","DOIUrl":"10.14797/mdcvj.1619","url":null,"abstract":"<p><p>Perimenopause, or menopause transition (MT), is a critical life stage that encompasses significant physiological, emotional, and psychosocial changes that impact women's cardiovascular health and quality of life. The decline in estrogen during MT induces adverse metabolic changes that increase the risk of dyslipidemia, obesity, insulin resistance, atherogenesis, and poor downstream outcomes such as diabetes, hypertension, stroke, and other adverse changes. Concurrently, stress plays an important role in shaping overall cardiovascular well-being during MT and long-term heart health post-menopause. In addition, nontraditional risk factors-particularly social determinants of health (SDoH) such as economic well-being, access to health care, built environment, social support, and others-are key upstream determinants of cardiovascular disease in women during perimenopause. Coordinated efforts are needed to screen, identify, and address the primary SDoH for optimal heart health in the clinically vulnerable MT patient population. Patient-centered care pathways that focus on assessing social needs and connecting socially vulnerable patients with available community resources are much needed for holistically addressing patient needs. Community-centered efforts are key to addressing persistent inequities in women's cardiovascular health via navigation and connection to community resources that may help address SDoH barriers.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"121-128"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Methamphetamine's Devastating Scourge.","authors":"Samra Iqbal, Justin C Cordova, James B Young","doi":"10.14797/mdcvj.1568","DOIUrl":"10.14797/mdcvj.1568","url":null,"abstract":"<p><p>This edition of Poet's Pen focuses on a rare but catastrophic complication associated with methamphetamine, the use of which is progressively rising in certain parts of the country. The featured poem, \"The Pulse of a Silent Killer,\" shows the utility of poetry to sound the alarm amidst an emergency, alerting the medical community that all may not be as it seems. According to its author, the piece \"reflects the rising crisis of methamphetamine-induced cardiomyopathy among young adults in Texas. This devastating condition, often overlooked, strikes with increasing frequency, leaving young lives cut short and communities shattered. The poem captures the silent but powerful toll of the epidemic and offers both a mournful reflection on lives lost and a call to action for those in the medical field to rise to the challenge of prevention and care. The painful panoply of substance abuse is one that captures many, and methamphetamine is but one of several illicit drugs that have become attractive to use. It is highly addictive, being abused largely on account of the stimulant effects that seem to be uniquely attractive to younger users. Though the euphoric effects of methamphetamine are short-lived, its long-term implications-including the cardiomyopathy associated with its use-can be challenging to diagnose, difficult to treat, and quickly result in disastrously permanent consequences.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"129-132"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenneth Wade Williams, Helene DiGregorio, Deepak Jagannath, Attila Feher
{"title":"CAD at the Intersection of Cardiology and Rheumatology: Focus on Cardiovascular Imaging.","authors":"Kenneth Wade Williams, Helene DiGregorio, Deepak Jagannath, Attila Feher","doi":"10.14797/mdcvj.1646","DOIUrl":"10.14797/mdcvj.1646","url":null,"abstract":"<p><p>Patients with autoimmune rheumatologic diseases (ARDs) exhibit an elevated risk for atherosclerosis, not fully accounted for by traditional risk factors alone. This review aims to explore how advanced multimodality cardiovascular imaging techniques can provide critical insights into the shared inflammatory pathways that contribute to endothelial damage and the development of atherosclerotic coronary artery disease. By highlighting the diagnostic potential and future applications of these techniques, we aim to provide a comprehensive overview for clinicians and researchers.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"21 4","pages":"65-75"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}