{"title":"Malignant Pericardial Effusion: Heart-Breaking Tumors.","authors":"Mohammed A R Chamsi-Pasha","doi":"10.14797/mdcvj.1761","DOIUrl":"10.14797/mdcvj.1761","url":null,"abstract":"<p><p>Pericardial effusion secondary to an underlying neoplasm carries a poor prognosis because it often represents an advanced stage of malignancy. In approximately one-third of affected patients, the initial presentation may be cardiac tamponade.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"110-113"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Cardiac MRI and CT in Pericarditis and Pericardial Constriction.","authors":"Kazim Baser, Nisha Ali, Yeva Fakikh, Sadeer Al-Kindi, Mouaz Al-Mallah, Dipan Shah, Maan Malahfji","doi":"10.14797/mdcvj.1779","DOIUrl":"10.14797/mdcvj.1779","url":null,"abstract":"<p><p>Pericardial diseases span a spectrum from acute and recurrent pericarditis to chronic constrictive pericarditis. While echocardiography remains the first-line test in the evaluation of patients with suspected pericardial disease, advanced cardiac imaging with cardiac magnetic resonance and computed tomography have become complementary and often essential in refining diagnosis and guiding management in many patients. The recent Concise Clinical Guidance Statement from the American College of Cardiology as well as updated European Society of Cardiology guidelines have given new emphasis and recommendations on the use of advanced imaging in both pericarditis and pericardial constriction. This review summarizes the techniques, indications, and recent studies on the use of advanced cardiac imaging in pericarditis and pericardial constriction.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"41-49"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Envisioning the Heart.","authors":"Philip Alexander, Muhammad Umair","doi":"10.14797/mdcvj.1758","DOIUrl":"10.14797/mdcvj.1758","url":null,"abstract":"<p><p>Philip Alexander, MD, is a native Texan, retired physician, and accomplished musician and artist. After 41 years as an internal medicine physician, Dr. Phil retired from his practice in College Station in 2016. A lifelong musician and former music professor, he often performs as an oboe soloist for the Brazos Valley Symphony Orchestra. He began exploring visual art in 1980, evolving from pencil sketches-including an official White House portrait of President Ronald Reagan-to the computer-generated drawings featured in this journal. His images, which first appeared in this journal in the spring of 2012, are his own original creations. This issue of the <i>Journal</i> also includes an artistic submission by Muhammad Umair, MD, assistant professor of radiology at the New York Presbyterian Hospital-Columbia University, whose work focuses on cardiovascular imaging (MRI and CT). He adds that he \"sometimes indulges in abstract paintings, inspired by his work in cardiac and vascular imaging.\" If you would like to see your art published in the <i>Methodist DeBakey Cardiovascular Journal</i>, submit your creation online at journal.houstonmethodist.org as a \"Humanities\" entry.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"121-123"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Constrictive Pericarditis and Effusive Constrictive Pericarditis: Is There a Role for Medical Therapy?","authors":"Lamis El Harake, Mohamed Al-Kazaz, Paul C Cremer","doi":"10.14797/mdcvj.1788","DOIUrl":"10.14797/mdcvj.1788","url":null,"abstract":"<p><p>Constrictive pericarditis (CP) represents a spectrum of pericardial diseases characterized by impaired ventricular filling due to a noncompliant pericardium. Within this continuum, effusive constrictive pericarditis (ECP) and transient constrictive pericarditis are characterized by active inflammation. ECP combines pericardial effusion and constrictive physiology, whereas transient constrictive pericarditis is characterized by resolution, often after anti-inflammatory therapy. These conditions often result from idiopathic, post-surgical, autoimmune, or tuberculous causes and may progress from acute inflammation to chronic fibrosis and calcification, termed chronic constrictive pericarditis. Multimodality imaging, including echocardiography, cardiac magnetic resonance imaging, and cardiac computed tomography, plays a key role in establishing the diagnosis, assessing inflammation, and guiding treatment. In patients with active pericardial inflammation, increasing evidence and practice supports the early and combined initiation of anti-inflammatory therapy including nonsteroidal agents, colchicine, corticosteroids, and interleukin-1 inhibitors to reverse constrictive pathophysiology.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"85-96"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relapsing Pericarditis: Prediction of Relapses, Risk Scores, and Role of Exercise Restriction.","authors":"Joseph El Roumi, Jibran Ikram, Tom Kai Ming Wang","doi":"10.14797/mdcvj.1777","DOIUrl":"10.14797/mdcvj.1777","url":null,"abstract":"<p><p>Relapsing pericarditis (RP) is a chronic inflammatory disorder characterized by two or more episodes of acute pericarditis flares after a minimum of a 4-week symptom-free period. Recurrent pericarditis develops in approximately 15% to 30% of patients following an initial episode of acute pericarditis, and nearly half of these individuals experience subsequent recurrences. Although the course is heterogeneous, RP has substantial morbidity and impaired quality of life implications and is associated with pericardial complications, including cardiac tamponade and constrictive pericarditis. This review summarizes current knowledge about clinical perspectives, predictors, and risk stratification tools for relapses in RP and critically appraises the evolving role of exercise restriction as part of RP management. Many adverse prognosticators for RP in clinical, laboratory, multimodality cardiac imaging, and treatment factors have been identified from clinical trials, observational studies, and experiences of managing RP patients. Several risk scores have been recently developed to assist in risk stratification and treatment guidance for RP patients, such as the Athens, Torino, INFLA, and Klein scores. There is also growing evidence for exercise restriction strategies with a focus on practical individualized strategies in the multimodal treatment of RP that have been included in recent pericarditis guidance documents. Multicenter external validation and randomized trials remain necessary to assess the roles and performance of risk scores and exercise restriction in treating RP to improve their clinical outcomes.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"14-26"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Multimodal Cardiac Imaging in Pericardial Effusions and Tamponade.","authors":"Rohan A Gajjar, Tahir S Kafil, Sushil Allen Luis","doi":"10.14797/mdcvj.1784","DOIUrl":"10.14797/mdcvj.1784","url":null,"abstract":"<p><p>Pericardial effusion represents a common clinical entity encountered across diverse medical settings, with presentations ranging from incidental findings to life-threatening cardiac tamponade. The accurate diagnosis and management of pericardial effusion and its hemodynamically significant sequelae demand a comprehensive multimodality imaging approach. Echocardiography remains the cornerstone of initial evaluation, providing real-time assessment of effusion size, hemodynamic impact, and guidance for therapeutic interventions. This review synthesizes contemporary evidence from major cardiology societies to present a structured approach to the diagnosis and management of pericardial effusion and tamponade. We emphasize the pivotal role of echocardiography while integrating complementary modalities, including cardiac computed tomography and cardiac magnetic resonance imaging. Key echocardiographic findings, Doppler parameters, and imaging-guided therapeutic strategies are discussed in detail, with attention to emerging techniques and evidence-based algorithms. Understanding the multimodality imaging approach is essential for optimizing patient outcomes in this potentially life-threatening condition.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"60-73"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Otherwise: A Discussion of Jane Kenyon and Her Place in the Medical Humanities.","authors":"Justin C Cordova, James B Young","doi":"10.14797/mdcvj.1717","DOIUrl":"10.14797/mdcvj.1717","url":null,"abstract":"<p><p>Jane Kenyon (1947-1995) died from leukemia in 1995, a writer in her prime whose work was steadily rising in popularity and amassing critical acclaim. Earlier that year, she had been appointed Poet Laureate of New Hampshire and left behind a rich body of work, including \"Otherwise\"-the featured work in this Poet's Pen. Kenyon was married to fellow writer Donald Hall (1928-2018) and wrote this piece in response to her husband's presumptively terminal cancer diagnosis. Though Hall's writings have been used extensively in the medical humanities, an argument can be made that several of Kenyon's works are just as worthy of inclusion. Many of her poems provide important insights into topics like bereavement, caregiving, and mental illness, making them ideally suited for consideration as part of health humanities education.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"117-120"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lamis El Harake, Mohamed Al-Kazaz, Paul C Cremer, Douglas R Johnston
{"title":"Perioperative and Surgical Management of Constrictive Pericarditis.","authors":"Lamis El Harake, Mohamed Al-Kazaz, Paul C Cremer, Douglas R Johnston","doi":"10.14797/mdcvj.1789","DOIUrl":"10.14797/mdcvj.1789","url":null,"abstract":"<p><p>Constrictive pericarditis represents a form of severe diastolic heart failure characterized by impaired diastolic filling due to a rigid, noncompliant pericardium. Surgical pericardiectomy is the definitive treatment for chronic or refractory subacute constrictive pericarditis; however, outcomes vary widely depending on disease etiology, chronicity, myocardial involvement, end-organ dysfunction, and surgical technique. This review summarizes contemporary best practices for the surgical management of constrictive pericarditis, with emphasis on patient selection, timing of intervention, operative approach, and perioperative considerations. Accurate differentiation between inflammatory, transient constrictive phenotypes and irreversible fibrotic disease is central to therapeutic decision-making. Etiology-based risk stratification, assessment of hepatic and renal dysfunction, and careful evaluation of myocardial involvement provide critical prognostic information. Multimodality imaging plays a central role in diagnosis, surgical planning, and identification of patients most likely to benefit from intervention. Radical pericardiectomy is associated with superior functional recovery compared with partial resection, whereas radiation-associated disease, mixed constrictive-restrictive physiology, and advanced end-organ dysfunction are consistently linked to worse outcomes. High-volume centers of excellence in pericardial disease are critical in optimizing results after radical pericardiectomy.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"97-109"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemodynamics of Pericardial Constriction: Role of Echocardiography and Cardiac Catheterization.","authors":"David M Harmon, Jae K Oh","doi":"10.14797/mdcvj.1781","DOIUrl":"10.14797/mdcvj.1781","url":null,"abstract":"<p><p>Constrictive pericarditis is a condition of diastolic heart failure with unique hemodynamic manifestations. While potentially curable if treated appropriately, constrictive pericarditis remains a diagnostic challenge, particularly during early manifestation of disease when there are subtle clinical symptoms and when confounding comorbidities are present. In this focused review, we describe the characteristic and diagnostic hemodynamics of constrictive pericarditis as well as the utility of invasive (cardiac catheterization) and noninvasive (echocardiography) diagnostic testing for this complex disease.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 2","pages":"74-84"},"PeriodicalIF":0.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12985938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronary Conundrum: Anomalous Pan-Coronary Origin from the Right Sinus with a \"Type X\" Dual LAD.","authors":"Abhinand J, Anil Kumar Choudhary, Neeraj Rao, Shrividya Rao, Devesh Kumar","doi":"10.14797/mdcvj.1775","DOIUrl":"10.14797/mdcvj.1775","url":null,"abstract":"<p><p>A 49-year-old man presented with acute onset chest pain and new-onset right bundle branch block. Echocardiography revealed mild apical hypokinesia with an ejection fraction of 45%. Coronary angiography showed all three major coronary arteries originating from the right coronary sinus with normal flow. Further evaluation identified an obstructed accessory left anterior descending (LAD) artery arising from the left sinus. Successful wire crossing, balloon dilatation, and deployment of a drug-eluting stent restored TIMI 3 flow. Subsequent computed tomography angiography confirmed a rare Type X dual LAD anatomy. This case highlights the importance of recognizing uncommon coronary artery anomalies since they may significantly influence diagnostic and therapeutic strategies.</p>","PeriodicalId":39207,"journal":{"name":"Methodist DeBakey cardiovascular journal","volume":"22 1","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}