Dementia e Neuropsychologia最新文献

{"title":"Assessment of mental well-being and psychological distress in Moroccan breast cancer patients.","authors":"Meryam Belhaj Haddou, Hicham El Mouaddib, Zakaria Belhaj Haddou, Mouna Khouchani, Noureddine El Khoudri","doi":"10.1590/1980-5764-DN-2024-0145","DOIUrl":"10.1590/1980-5764-DN-2024-0145","url":null,"abstract":"<p><p>The quality of life of breast cancer patients is strongly affected by physical pain, psychological distress, and uncertainty about vital prognosis.</p><p><strong>Objective: </strong>To assess breast cancer patients' mental well-being and level of psychological distress at the Mohammed VI University Hospital in Marrakech.</p><p><strong>Methods: </strong>Cross-sectional study carried out from April to December 2023 at the Mohammed VI University Hospital of Marrakech. The data were collected via a questionnaire comprising a sociodemographic section and a section reserved for the Warwick-Edinburgh Mental Well-being Scale (WEMWBS) and the Kessler Psychological Distress Scale (K10). Data analysis was performed using SPSS software, version 25.</p><p><strong>Results: </strong>A total of 38.3% of patients experienced severe psychological distress. However, their mental well-being was high with a mean of 54.59 (±11.29). Older patients (>50 years) exhibited better mental well-being (56.46±10.39 vs. 52.99±11.81; p=0.020) and lower psychological distress (26.27±7.21 vs. 28.44±8.19; p=0.034) compared to their younger counterparts (≤50 years). As for the stage of cancer, patients with localized cancer presented a higher mental well-being score than patients with metastatic cancer (55.53±10.93 vs. 50.40±12.03; p=0.008). However, no statistically significant difference was recorded between mastectomy and lumpectomy patients regarding mental well-being or psychological distress.</p><p><strong>Conclusion: </strong>Breast cancer has not only a physical but also a psychological and emotional impact on patients. Thus, early diagnosis and referral to appropriate psychosocial services can improve patients' mental well-being.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240145"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in evaluating cognitive impairment in diabetics in the Democratic Republic of the Congo.","authors":"David Shamputi, Célestin Kaputu-Kalala-Malu, Bives Mutume Nzanzu Vivalya, Stella-Maria Paddick, Raj Kalaria","doi":"10.1590/1980-5764-DN-2023-0082","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2023-0082","url":null,"abstract":"<p><p>Dementia is a global public health issue, with 57.5 million people living with at least one type of dementia in 2019 worldwide, and projected to rise to 152 million by 2050.</p><p><strong>Objective: </strong>We assessed the cognitive function in diabetic patients aged 60 or older in Bukavu city, in the eastern Republic of the Congo (DRC).</p><p><strong>Methods: </strong>This case-control study involved 123 patients with established diabetes mellitus (DM) and 123 controls over 60-year-olds also with high rates of illiteracy. Cognitive function was assessed using the Swahili version of the Community Screening Instrument for Dementia (CSI-D).</p><p><strong>Results: </strong>Foremost, our study revealed language-related differences between Swahili spoken in other eastern African countries such as Tanzania and Kenya, where the Swahili CSI-D is readily applied, compared to the Swahili spoken in Bukavu (DRC). Our results also showed that cognitive impairment was present in 18.7% of the total 246 participants. Remarkably, the prevalence rate of cognitive impairment was higher in the non-diabetic group (12.2 versus 25.2%; p=0.009). Participants aged 80 or older were more likely to present with cognitive impairment compared to those aged less than 80 (adjusted odds ratio - aOR=70.27; 95% confidence interval - 95%CI 3.94-125.15; p=0.004). We also found that patients living with DM for more than 20 years were three times more likely to be impaired compared to those who were recently diagnosed with DM (aOR=3.63; 95%CI 1.70-18.81; p=0.026).</p><p><strong>Conclusion: </strong>This study revealed that cognitive impairment was relatively high in Bukavu city. It emphasizes the lack of effective tools to assess cognitive function. This requires, therefore, that research be adapted to the intellect and cultural experiences of the patients.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230082"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular cognitive impairment and dementia: a narrative review.","authors":"Amado Jiménez-Ruiz, Victor Aguilar-Fuentes, Naomi Nazareth Becerra-Aguiar, Ivan Roque-Sanchez, Jose Luis Ruiz-Sandoval","doi":"10.1590/1980-5764-DN-2023-0116","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2023-0116","url":null,"abstract":"<p><p>Vascular cognitive impairment (VCI) is the second most common cause of cognitive impairment after Alzheimer's disease. The VCI spectrum involves a decline in cognition attributable to vascular pathologies (e.g., large infarcts or hemorrhages, microinfarcts, microbleeds, lacunar infarcts, white matter hyperintensities, and perivascular space dilation). Pathophysiological mechanisms include direct tissue injury, small vessel disease, inflammaging (inflammation + aging), atrophy, and altered neurotransmission. VCI is diagnosed using distinct clinical and radiological criteria. It may lead to long-term disability and reduced quality of life. An essential factor for reducing cognitive impairment incidence is preventing stroke by managing traditional and non-traditional cerebrovascular risk factors. This article reviews the spectrum of VCI, epidemiology, risk factors, pathophysiology, diagnosis, available treatment, and preventive strategies.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230116"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of clinical efficacy and safety of cell-based therapies in Alzheimer's disease.","authors":"Hamidreza Feizi, Mohammad-Salar Hosseini, Sepideh Seyedi-Sahebari, Hanie Karimi, Reza Mosaddeghi-Heris, Saeed Sadigh-Eteghad, Fatemeh Sadeghi-Ghyassi, Mahnaz Talebi, Amirreza Naseri, Hanieh Salehi-Pourmehr, Leila Roshangar","doi":"10.1590/1980-5764-DN-2024-0147","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2024-0147","url":null,"abstract":"<p><p>There is presently no disease-modifying therapy for Alzheimer's Disease (AD), which is the most prevalent cause of dementia.</p><p><strong>Objective: </strong>This study aspires to estimate the efficacy and safety of cell-based treatments in AD.</p><p><strong>Methods: </strong>Observing the Joanna Briggs Institute (JBI) methods and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a systematic search was accomplished in PubMed, Medical Literature Analysis and Retrieval System Online (Medline, via Ovid), Embase; Cochrane, and Cumulative Index of Nursing and Allied Health Literature - CINAHL (via EBSCO) databases up to June 2023. The relevant clinical studies in which cell-based therapies were utilized to manage AD were included. The risk of bias was evaluated using the JBI checklists, based on the study designs.</p><p><strong>Results: </strong>Out of 1,014 screened records, a total of five studies with 70 individuals (including 59 patients receiving stem cells and 11 placebo controls) were included. In all these studies, despite the discrepancy in the origin of stem cells, cell density, and transplant site, safety goals were obtained. The intracerebroventricular injection of adipose-derived stromal vascular fraction (ADSVF) and umbilical cord-derived mesenchymal stem cells (UC-MSCs), the intravenous injection of Lomecel-B, and the bilateral hippocampi and right precuneus injection of UC-MSCs are not linked to any significant safety concerns, according to the five included studies. Studies also revealed improvements in biomarkers and clinical outcomes as a secondary outcome. Three studies had no control groups and there are concerns regarding the similarity of the groups in others. Also, there is considerable risk of bias regarding the outcome assessment scales.</p><p><strong>Conclusion: </strong>Cell-based therapies are well tolerated by AD patients, which emphasizes the need for further, carefully planned randomized studies to reach evidence-based clinical recommendations in this respect.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240147"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11386524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five Digit Test in neuropsychological assessment of working memory in aged individuals:normative data.","authors":"Juliana Francisca Cecato","doi":"10.1590/1980-5764-DN-2024-0141","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2024-0141","url":null,"abstract":"<p><p>Five Digit Test (FDT) is an executive function assessment tool designed to be used across the lifespan, from children to the aged.</p><p><strong>Objective: </strong>To provide validity evidence for FDT in the neuropsychological assessment of working memory in the aged.</p><p><strong>Methods: </strong>A total of 100 subjects, aged between 56 and 86 years, representing both genders with varying levels of education, underwent a comprehensive clinical history and neuropsychological evaluation using FDT. The mean age of participants was 71.04 years, with 67.3% having intermediate education. Participants were categorized into two groups: Control Group and Cognitive Decline Group. To establish validity evidence, FDT scores (both time and errors) were correlated with the WAIS-III Digits scale. Spearman's correlation coefficient and ROC curve methodology were employed to determine psychometric properties.</p><p><strong>Results: </strong>A significant and moderate negative correlation was evident between FDT Shifting (number of errors) and Digits score (rho=-0.51; p<0.0001), Direct Order (rho=-0.39; p<0.0001), and Indirect Order (rho=-0.46; p<0.0001). The area under the curve was higher for FDT Shifting (errors) (AUC=0.935) for a cutoff point greater than or equal to 5 points, compared to Digits (AUC=0.748).</p><p><strong>Conclusion: </strong>The assessment of the number of errors in FDT Shifting appears to be a statistically significant tool for evaluating working memory impairment in the aged.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240141"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11386523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between cognitive screening performance and motor symptoms in Parkinson's disease:a systematic review and meta-analysis.","authors":"Karlee Patrick, Elizabeth Cousins, Mary Beth Spitznagel","doi":"10.1590/1980-5764-DN-2023-0102","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2023-0102","url":null,"abstract":"<p><p>Although the most prominent symptoms of Parkinson's disease (PD) are those impacting movement, cognitive dysfunction is prevalent and often presents early in the disease process. Individuals with cognitive symptoms of PD often complete cognitive screening, making it important to identify factors associated with cognitive screening performance to ensure prompt and accurate detection of cognitive impairments.</p><p><strong>Objective: </strong>Despite a body of research examining relationships between motor symptoms and cognitive dysfunction in PD, no prior study has undertaken a systematic review of the magnitude of the relationship between motor symptoms and cognitive screening performance in PD.</p><p><strong>Methods: </strong>This study was a systematic review and meta-analysis of the relationship between cognitive screening performance, as assessed by the Montreal Cognitive Assessment (MoCA), and motor symptoms of PD. After the systematic screening, 20 studies were included, and meta-regressions using mixed-effects models were conducted.</p><p><strong>Results: </strong>Motor symptoms across included studies were relatively mild, but average MoCA scores were at the established cutoff for risk of dementia in PD. The average disease duration was 5 years. Consistent with hypotheses, more severe motor symptoms were associated with lower MoCA scores (<i>r=</i>-0.22 (95%CI -0.29 to -0.16), p<0.001), indicating worse cognitive functioning.</p><p><strong>Conclusion: </strong>The results indicate a significant negative correlation between MoCA performance and motor symptoms of PD. Average MoCA scores captured early disease-stage cognitive impairment when motor symptoms remained relatively mild. Serial screening for cognitive impairment beginning early in the disease course may be of benefit to ensure that cognitive dysfunction is detected as it arises.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230102"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11386525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Montreal Cognitive Assessment a valuable test for the differentiation of Alzheimer's disease, frontotemporal dementia, dementia with Lewy body, and vascular dementia?","authors":"Fatemeh Afrashteh, Mostafa Almasi-Dooghaee, Naser Kamyari, Rayan Rajabi, Hamid Reza Baradaran","doi":"10.1590/1980-5764-DN-2023-0124","DOIUrl":"10.1590/1980-5764-DN-2023-0124","url":null,"abstract":"<p><p>Dementia is one of the growing diseases in the world and has different types based on its definition. The Montreal Cognitive Assessment (MoCA) test has been employed to screen patients with dementia, cognitive impairment, and disruption of daily activities.</p><p><strong>Objective: </strong>This study examined the diagnostic value of the total MoCA score and its subscores in differentiating Alzheimer's disease (AD), frontotemporal dementia (FTD), dementia with Lewy body (DLB), and vascular dementia (VaD).</p><p><strong>Methods: </strong>A total of 241 patients (AD=110, FTD=90, DLB=28, and VaD=13) and 59 healthy persons, who were referred to a dementia clinic with memory impairment in Firoozgar Hospital, were included in this study. MoCA tests were performed in all patients and normal persons.</p><p><strong>Results: </strong>By using the receiver operating characteristic (ROC) curve and measuring the area under the curve (AUC) for the total MoCA score in each group, AUC was 0.616, 0.681, 0.6117, and 0.583 for differentiating AD, FTD, DLB, and VaD patients, respectively. Among the groups, just the VaD group showed no significant usefulness in using the total MoCA score to differentiate it. To compare MoCA subscores, AD patients had higher scores in digit span, literal fluency, and abstraction but lower delayed recall scores compared with FTD patients.</p><p><strong>Conclusion: </strong>The total MoCA score and its subscores could not differentiate people with different types of dementia in the setting of screening.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230124"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation, testing, and use of the \"iSupport for Dementia\" program in different countries: a systematic review.","authors":"Larissa Corrêa, Aline Cristina Martins Gratão, Déborah Oliveira, Elizabeth Joan Barham, Fabiana de Souza Orlandi, Keila Cristianne Trindade da Cruz, Ana Carolina Ottaviani, Diana Quirino Monteiro, Gustavo Carrijo Barbosa, Anabel Machado Cardoso Alvarenga Pilegis, Luana Aparecida da Rocha, Ludmyla Caroline de Souza Alves, Luiza Barros Maciel, Camila Rafael Ferreira Campos, Sofia Cristina Iost Pavarini","doi":"10.1590/1980-5764-DN-2023-0097","DOIUrl":"10.1590/1980-5764-DN-2023-0097","url":null,"abstract":"<p><p>The World Health Organization developed the \"iSupport for Dementia\" program for family caregivers of people with dementia.</p><p><strong>Objective: </strong>To explore studies on adaptation, randomized clinical trial protocols, and preliminary results of iSupport by unpaid caregivers of people living with dementia in different countries.</p><p><strong>Methods: </strong>Systematic review.</p><p><strong>Results: </strong>Ten cultural adaptation studies, eight randomized clinical trial protocols, and two preliminary results were included. Adaptation studies showed adjustments in terminology, design, and additional resources. Clinical trial protocols included burden as the primary outcome, and baseline, three months of intervention, and follow-up after six months. Studies with preliminary results found positive effects on the mental health and well-being of caregivers after using the program.</p><p><strong>Conclusion: </strong>iSupport is an online program of the World Health Organization in response to dementia in implementation in different countries.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230097"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life in persons with mild cognitive impairment: a systematic review and meta-analysis.","authors":"Priya Gopalakrishnan, Shivani Tiwari, Ravishankar Nagaraja, Gopee Krishnan","doi":"10.1590/1980-5764-DN-2023-0093","DOIUrl":"10.1590/1980-5764-DN-2023-0093","url":null,"abstract":"<p><p>The global increase in the aging population has raised concerns over various age-related conditions like dementia and mild cognitive impairment (MCI) and their consequences on the affected persons. People with MCI exhibit cognitive deficits more significantly than expected for their age and literacy level. Though the nature of this condition is considered \"mild\", studies have reported that even more subtle deficits can influence the quality of life (QOL).</p><p><strong>Objective: </strong>The present work aimed at exploring and comparing QOL in older adults with and without MCI through a systematic review and meta-analysis.</p><p><strong>Methods: </strong>After a detailed search of articles till May 2021 in the relevant electronic databases (PubMed Central, PubMed, Scopus, CINAHL Plus, Web of Science, ProQuest, and Cochrane) using the keywords \"mild cognitive impairment\", \"quality of life\", \"old\", \"old aged\", \"aged\", \"older adult\", \"geriatrics\", \"healthy controls\", \"healthy participants\", and \"normal controls\", we included 23 articles in the systematic review and 12 in the meta-analysis.</p><p><strong>Results: </strong>The quality of all the included articles were assessed using the Modified Downs and Black tool. Most of the studies in the systematic review demonstrated differences in QOL scores in older adults with MCI compared to healthy older adults. However, meta-analysis findings suggest that older adults with MCI had statistically non-significant yet lower differences in QOL compared to their healthy counterparts.</p><p><strong>Conclusion: </strong>Future research should focus on developing QOL assessment tools specifically for older adults with MCI and follow-up studies that could provide better knowledge of their changing cognitive profile and life quality.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230093"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between sleep and Alzheimer's disease: a systematic review.","authors":"Paul Nichol Galan Gonzales, Steven Gayoles Villaraza, Joseree-Ann Catindig Dela Rosa","doi":"10.1590/1980-5764-DN-2023-0049","DOIUrl":"10.1590/1980-5764-DN-2023-0049","url":null,"abstract":"<p><p>It is estimated that 45% of individuals with cognitive impairment experience sleep disturbances prior to the onset of cognitive symptoms. Assessing sleeping problems and enhancing sleep quality are critical first steps to reduce the risk of cognitive impairment.</p><p><strong>Objective: </strong>To review existing literature based on predefined eligibility criteria to understand the connection between sleep disturbance and Alzheimer's disease.</p><p><strong>Methods: </strong>A thorough and systematic evaluation of numerous studies was carried out to assess one or more of the following epidemiological factors: (1) sleep disorders, (2) cognitive impairment, and (3) risk estimates for cognitive impairment due to sleep.</p><p><strong>Results: </strong>Studies suggest that individuals who experience memory loss may encounter sleep disturbances before noticing other symptoms. Numerous sleep disorders, such as excessive and inadequate sleep duration, poor sleep quality, circadian rhythm abnormalities, insomnia, and obstructive sleep apnea were found to increase the risk of cognitive dysfunction and dementia. Additionally, lower sleep quality and shorter sleep duration have been linked to higher cerebral-β-amyloid levels. Objective evidence for the development of cognitive impairment is provided by the architecture of sleep stages. Patients experiencing sleep problems may benefit from specific types of sleep medicine as a preventative measure against cognitive decline.</p><p><strong>Conclusion: </strong>Sleep disorders can have adverse effects on cognitive health. The duration and quality of sleep are fundamental factors for maintaining a healthy brain as we age. Proper sleep can aid prevent cognitive impairment, particularly Alzheimer's disease and dementia.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230049"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}