Dementia e Neuropsychologia最新文献_第3页

Reply to familial dysfunction and cognitive decline in aging: the "health, wellbeing, and aging" (SABE) longitudinal population-based study. 对家庭功能障碍和衰老认知能力下降的回应：“健康、幸福和衰老”（SABE）纵向人群研究。

Dementia e Neuropsychologia Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0146R

Diego Ferreira da Silva, Juliana Nery Souza-Talarico, Jair Licio Ferreira Santos, Yeda Aparecida de Oliveira Duarte

引用次数: 0

Familial risk of cognitive changes in the elderly. 老年人认知变化的家族性风险。

Dementia e Neuropsychologia Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0146

Johnnatas Mikael Lopes, Amanda Cirilo de Oliveira Lins, Rafael Limeira Cavalcanti, Jeisyane Acsa Santos do Nascimento, Luan Andrade Carvalho, Pedro Vitor Vieira Freire, Anna Beatriz Machado Lima, Achilles de Souza Andrade

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Standardization in the judgment of line orientation test in elderly people in Northeast Brazil. 巴西东北部老年人线取向测试判断的规范化。

Dementia e Neuropsychologia Pub Date : 2024-12-02 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0130

Paulo Roberto de Brito-Marques, Janaina Mariana de Araujo Miranda Brito-Marques, Cácia Carolina de Carvalho Silva Miranda, Herickssen Gustavo Medeiros-Silva

{"title":"Standardization in the judgment of line orientation test in elderly people in Northeast Brazil.","authors":"Paulo Roberto de Brito-Marques, Janaina Mariana de Araujo Miranda Brito-Marques, Cácia Carolina de Carvalho Silva Miranda, Herickssen Gustavo Medeiros-Silva","doi":"10.1590/1980-5764-DN-2024-0130","DOIUrl":"10.1590/1980-5764-DN-2024-0130","url":null,"abstract":"Aging is generally associated with a decline in cognition when compared to adulthood. The changes most seen are in attention, perception, working memory, short-term memory, free recall, and processing speed. Certain changes in the Judgment of Line Orientation (JLO) test may be present in elderly people.Objective: The objective of this study was to describe the difference among age, sex, schooling, Mini-Mental State (MMS), and Mini-Mental State Examination (MMSE) when compared to the JLO test in elderly people. The second is to assess the clinical use of the JLO test in elderly people's cognitive decline in Northeast Brazil.Methods: A cross-sectional, randomized study was carried out on 280 elderly people, between 60 and 89 years old, and the mean age was 69.4 (±6.8 years SD); 73.9% of the females lived in Olinda City, State of Pernambuco, Brazil. Age was stratified every 5 years between 60 and 89 years old, and schooling was divided into four subgroups between illiterate and more than 8 years of schooling. Each participant was submitted to an analysis of age, sex, schooling, risk factors, MMS, modified MMSE, and a JLO test.Results: There was no statistical difference between the sexes. However, there was a statistical difference when compared to the JLO test and age (p<0.012), schooling (p<0.001), MMS (p<0.001), and modified MMSE (p<0.001).Conclusion: We observed that with a cutoff point of 18 points, the JLO test is indicated to assess visuospatial and visuoperceptive changes in elderly people in Northeast Brazil.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240130"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Promoting multilingualism in dementia research, prevention, and discourse. 在痴呆症的研究、预防和论述中促进使用多种语言。

Dementia e Neuropsychologia Pub Date : 2024-12-02 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0201

Timothy Daly

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Toward enhanced understanding and rigor: addressing limitations in studying dementia symptoms and caregiver interventions. 增强理解和严谨性：解决研究痴呆症状和护理干预的局限性。

Dementia e Neuropsychologia Pub Date : 2024-11-29 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0148

Guilherme Nobre Nogueira, Wilson da Silva Rocha Vidal, Nicole Custódio Porto Silva

引用次数: 0

Executive functions, mental health, and quality of life in healthy older adults. 健康老年人的执行功能、心理健康和生活质量。

Dementia e Neuropsychologia Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0156

Cássia Elisa Rossetto Verga, Gabriela Dos Santos, Tiago Nascimento Ordonez, Ana Paula Bagli Moreira, Laydiane Alves Costa, Luiz Carlos de Moraes, Patrícia Lessa, Neide Pereira Cardoso, Gustavo Domingos França, Ambrósio Ferri, Beatriz Aparecida Ozello Gutierrez, Henrique Salmazo da Silva, Sonia Maria Dozzi Brucki, Thais Bento Lima da Silva

{"title":"Executive functions, mental health, and quality of life in healthy older adults.","authors":"Cássia Elisa Rossetto Verga, Gabriela Dos Santos, Tiago Nascimento Ordonez, Ana Paula Bagli Moreira, Laydiane Alves Costa, Luiz Carlos de Moraes, Patrícia Lessa, Neide Pereira Cardoso, Gustavo Domingos França, Ambrósio Ferri, Beatriz Aparecida Ozello Gutierrez, Henrique Salmazo da Silva, Sonia Maria Dozzi Brucki, Thais Bento Lima da Silva","doi":"10.1590/1980-5764-DN-2024-0156","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2024-0156","url":null,"abstract":"Population aging brings about numerous challenges, particularly concerning cognitive health. In this context, socioeconomic factors such as education have received special attention due to their role in brain health.Objective: The aim of this study was to describe the performance of executive functions, mental health variables, and quality of life among healthy older adults in relation to their level of education.Methods: A descriptive, cross-sectional study was conducted with participants aged 60 or older. The assessment protocol included Addenbrooke's cognitive examination and FAS, trail-making tests A and B, Control, Autonomy, Self-Realization, and Pleasure Scale (CASP-19), as well as the depression, anxiety, and stress scale.Results: Significant differences were found in the performance of executive functions among older adults with higher levels of education. However, mental health and quality of life variables were only related to participants' age.Conclusion: The study showed that mental health and quality of life are not influenced by participants' level of education but are instead strongly correlated with age.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240156"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of anti-amyloid therapies for Alzheimer's disease in Brazil: a position paper from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology. 巴西使用抗淀粉样蛋白疗法治疗阿尔茨海默病：巴西神经病学学会认知神经学和老龄化科学部的立场文件。

Dementia e Neuropsychologia Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-C002

Breno José Alencar Pires Barbosa, Elisa de Paula França Resende, Raphael Machado Castilhos, Wyllians Vendramini Borelli, Norberto Anízio Ferreira Frota, Marcio Luiz Figueredo Balthazar, Augusto Celso Scarparo Amato, Jerusa Smid, Maira Tonidandel Barbosa, Artur Martins Coutinho, Leonardo Cruz de Souza, Lucas Porcello Schilling, Mari Nilva Maia da Silva, Gustavo Bruniera Peres Fernandes, Paulo Henrique Ferreira Bertolucci, Ricardo Nitrini, Eliasz Engelhardt, Orestes Vicente Forlenza, Paulo Caramelli, Sonia Maria Dozzi Brucki, Adalberto Studart

{"title":"Use of anti-amyloid therapies for Alzheimer's disease in Brazil: a position paper from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology.","authors":"Breno José Alencar Pires Barbosa, Elisa de Paula França Resende, Raphael Machado Castilhos, Wyllians Vendramini Borelli, Norberto Anízio Ferreira Frota, Marcio Luiz Figueredo Balthazar, Augusto Celso Scarparo Amato, Jerusa Smid, Maira Tonidandel Barbosa, Artur Martins Coutinho, Leonardo Cruz de Souza, Lucas Porcello Schilling, Mari Nilva Maia da Silva, Gustavo Bruniera Peres Fernandes, Paulo Henrique Ferreira Bertolucci, Ricardo Nitrini, Eliasz Engelhardt, Orestes Vicente Forlenza, Paulo Caramelli, Sonia Maria Dozzi Brucki, Adalberto Studart","doi":"10.1590/1980-5764-DN-2024-C002","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2024-C002","url":null,"abstract":"Novel therapies for Alzheimer's disease, particularly anti-amyloid drugs like lecanemab and donanemab, have shown modest clinical benefits but also significant risks. The present paper highlights the challenges of access to diagnosis, cost-effectiveness, safety, and the need for more representation of diverse populations in clinical trials. Recommendations include careful patient selection, risk-benefit analysis, and the importance of proven amyloid pathology for treatment. Future work involves further research on anti-amyloid therapies in Brazil and the development of more effective treatments for Alzheimer's disease.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e2024C002"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain morphometry in transient global amnesia: a triangulated analysis approach. 短暂性全面失忆症的大脑形态测量：三角分析法。

Dementia e Neuropsychologia Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-0163

Micaela Anahi Hernández, Hernán Chaves, Ricardo Francisco Allegri, Ismael Luis Calandri

{"title":"Brain morphometry in transient global amnesia: a triangulated analysis approach.","authors":"Micaela Anahi Hernández, Hernán Chaves, Ricardo Francisco Allegri, Ismael Luis Calandri","doi":"10.1590/1980-5764-DN-2024-0163","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2024-0163","url":null,"abstract":"Transient global amnesia (TGA) is a rare, temporary, sudden-onset disturbance in anterograde episodic memory with unclear pathophysiology. Previous brain volumetric analysis in TGA patients showed varied results.Objective: To explore brain morphometry, hypothesizing that patients with TGA exhibit structural alterations.Methods: A case-control study was performed involving TGA subjects (n=50) and matched healthy controls (n=50). Both groups underwent a 3D-T1 weighted structural MRI on a 3T scanner, and voxel-based morphometry (VBM), region-based morphometry (RBM), and surface-based morphometry (SBM) were analyzed.Results: After performing the VBM, RBM, and SBM analyses, no consistent and statistically significant differences were found after applying multiple corrections.Conclusion: Despite previous studies showing volumetric changes in TGA patients, our results differ from this. The discrepancy could be due to sample size and timing of MRI scans. While our findings do not explain TGA pathophysiology, they support a network dysfunction as a possible mechanism and discards a structural alteration as a predisposing factor for TGA.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240163"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guidelines for the use and interpretation of Alzheimer's disease biomarkers in clinical practice in Brazil: recommendations from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology. 巴西临床实践中阿尔茨海默病生物标记物的使用和解释指南：巴西神经病学学会认知神经学和老龄化科学部的建议。

Dementia e Neuropsychologia Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2024-C001

Adalberto Studart-Neto, Breno José Alencar Pires Barbosa, Artur Martins Coutinho, Leonardo Cruz de Souza, Lucas Porcello Schilling, Mari Nilva Maia da Silva, Raphael Machado Castilhos, Paulo Henrique Ferreira Bertolucci, Wyllians Vendramini Borelli, Hélio Rodrigues Gomes, Gustavo Bruniera Peres Fernandes, Maira Tonidandel Barbosa, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Orestes Vicente Forlenza, Jerusa Smid, Sonia Maria Dozzi Brucki, Paulo Caramelli, Ricardo Nitrini, Eliasz Engelhardt, Elisa de Paula França Resende

{"title":"Guidelines for the use and interpretation of Alzheimer's disease biomarkers in clinical practice in Brazil: recommendations from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology.","authors":"Adalberto Studart-Neto, Breno José Alencar Pires Barbosa, Artur Martins Coutinho, Leonardo Cruz de Souza, Lucas Porcello Schilling, Mari Nilva Maia da Silva, Raphael Machado Castilhos, Paulo Henrique Ferreira Bertolucci, Wyllians Vendramini Borelli, Hélio Rodrigues Gomes, Gustavo Bruniera Peres Fernandes, Maira Tonidandel Barbosa, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Orestes Vicente Forlenza, Jerusa Smid, Sonia Maria Dozzi Brucki, Paulo Caramelli, Ricardo Nitrini, Eliasz Engelhardt, Elisa de Paula França Resende","doi":"10.1590/1980-5764-DN-2024-C001","DOIUrl":"10.1590/1980-5764-DN-2024-C001","url":null,"abstract":"In recent years, the diagnostic accuracy of Alzheimer's disease has been enhanced by the development of different types of biomarkers that indicate the presence of neuropathological processes. In addition to improving patient selection for clinical trials, biomarkers can assess the effects of new treatments on pathological processes. However, there is concern about the indiscriminate and poorly supported use of biomarkers, especially in asymptomatic individuals or those with subjective cognitive decline. Difficulties interpreting these tests, high costs, and unequal access make this scenario even more challenging in healthcare. This article presents the recommendations from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology (Departamento Científico de Neurologia Cognitiva e Envelhecimento da Academia Brasileira de Neurologia) regarding the rational use and interpretation of Alzheimer's disease biomarkers in clinical practice. The clinical diagnosis of cognitive-behavioral syndrome is recommended as the initial step to guide the request for biomarkers.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e2024C001"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caring for people with dementia during the COVID-19 pandemic:a systematic review. 在 COVID-19 大流行期间照顾痴呆症患者：系统性综述。

Dementia e Neuropsychologia Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1590/1980-5764-DN-2023-0123

Juan Jesús Robles-García, José Ángel Martínez-López

{"title":"Caring for people with dementia during the COVID-19 pandemic:a systematic review.","authors":"Juan Jesús Robles-García, José Ángel Martínez-López","doi":"10.1590/1980-5764-DN-2023-0123","DOIUrl":"https://doi.org/10.1590/1980-5764-DN-2023-0123","url":null,"abstract":"Human history has been linked to numerous risks to survival, with pandemics being a constant in human life. People suffering from dementia experienced greater difficulties accessing healthcare and treatment during the COVID-19 pandemic.Objective: To identify how the COVID-19 pandemic influenced care for people with dementia or cognitive impairment.Methods: This research work is a systematic review conducted with a literature search in four databases such as Web of Science, Scopus, EBSCOHost, Cochrane Library, and ProQuest, following the methodological proposals of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guide.Results: The bibliographic research in the different databases offered a total of 561 records, of which 23 were chosen to elaborate the results. The main results were the increasing cognitive impairment and psychosocial consequences of social distancing during the pandemic, including sadness, helplessness, and abandonment in patients or feelings of burnout and overload in caregivers and health professionals.Conclusion: The COVID-19 placed patients with dementia in the background. During the pandemic, attention was focused primarily on emergencies and not so much on the monitoring of chronic diseases, which also caused psycho-emotional and social worsening.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20230123"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0