Dementia e Neuropsychologia最新文献

Cognitive and behavioral performance in children with epilepsy with myoclonic-atonic seizures. 儿童癫痫伴肌阵挛性失张力发作的认知和行为表现。

Dementia e Neuropsychologia Pub Date : 2025-07-11 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0249

Ericka Olívia Rodrigues Samoiloff, Denise Harumi Nakanishi, Eliane Correa Miotto

{"title":"Cognitive and behavioral performance in children with epilepsy with myoclonic-atonic seizures.","authors":"Ericka Olívia Rodrigues Samoiloff, Denise Harumi Nakanishi, Eliane Correa Miotto","doi":"10.1590/1980-5764-DN-2024-0249","DOIUrl":"10.1590/1980-5764-DN-2024-0249","url":null,"abstract":"Epilepsy with myoclonic-atonic seizures (EMAS), or Doose syndrome, is characterized by the presence of atonic-myoclonic seizures that begin in childhood between 7 months and 6 years of age, which may present with cognitive and behavioral changes.Objective: The aim of this present study was to evaluate adaptive behavior, performance on intelligence and neuropsychological tests, and verify the association of autism spectrum disorder and attention deficit hyperactivity disorder in patients diagnosed with EMAS compared with a control group of healthy children.Methods: We included nine patients with EMAS and nine healthy controls, assessed by scales of adaptive behavior development, autism spectrum disorder, attention deficit and hyperactivity, and intelligence and neuropsychological tests.Results: The results revealed that in the intelligence and neuropsychological tests, there was a significant difference between the groups (p>0.05), with worse performance for the EMAS group. In the latter group, eight patients showed some symptoms of attention deficit hyperactivity disorder and none showed symptoms of autism spectrum disorder or changes in adaptive behavior.Conclusion: These findings show the relevance of investigating cognitive and behavioral profiles in this population in order to address specific impairments in their everyday life activities.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240249"},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Episodic memory improvement in community-dwelling women following a remote language-based stimulation program. 社区妇女在远程语言刺激计划后情景记忆的改善。

Dementia e Neuropsychologia Pub Date : 2025-07-11 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0248

Vanessa Bisol, Bárbara Luzia Covatti Malcorra, Bárbara Rusch da Rocha, Ana Luiza Licodiedoff Peruzzo, Luciana Zanatta, Letícia Priscila Pacheco, Erica Dos Santos Rodrigues, Maria Teresa Carthery-Goulart, Lilian Cristine Hübner

{"title":"Episodic memory improvement in community-dwelling women following a remote language-based stimulation program.","authors":"Vanessa Bisol, Bárbara Luzia Covatti Malcorra, Bárbara Rusch da Rocha, Ana Luiza Licodiedoff Peruzzo, Luciana Zanatta, Letícia Priscila Pacheco, Erica Dos Santos Rodrigues, Maria Teresa Carthery-Goulart, Lilian Cristine Hübner","doi":"10.1590/1980-5764-DN-2024-0248","DOIUrl":"10.1590/1980-5764-DN-2024-0248","url":null,"abstract":"The increasing aging of the world's population has motivated studies leading to initiatives like developing online and face-to-face cognitive stimulation programs targeting typical and atypical aging populations. The decline in episodic memory (EM) capacity is one of the hallmarks of cognitive decline in Alzheimer's disease.Objective: The study analyzes the effect of a telepractice, composed exclusively of language activities, on five tasks of EM by comparing their scores in pre- and post-intervention assessments.Methods: Forty-nine (49) women aged 57-83 years (mean 68.1), with 6-22 (mean 15.1) years of formal education, engaged in a 15-session online intervention program delivered daily during the COVID-19 pandemic. A pre- and post-intervention cognitive assessment was administered, including five tasks assessing EM: two subtests of the verbal learning task of the Battery for the Assessment of Language in Aging (BALE) (free recall and with cues), the delayed recall subtest of the Addenbrooke's Cognitive Examination-Revised (ACE-R), the recall of the Brief Cognitive Screening Battery (BBRC) and the Face and Name Recall Test.Results: EM scores were consistently higher in the post-intervention assessments, with a significant improvement observed in four of the five EM tasks.Conclusion: The results bring implications for further research about telepractice, suggesting that typical older adults can benefit from language-based cognitive stimulation to prevent, reduce, or rehabilitate EM deficits.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240248"},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with psychotropic drugs use in older adults hospitalized in clinical and surgical wards of a university hospital. 某大学医院临床和外科病房住院的老年人精神药物使用的相关因素

Dementia e Neuropsychologia Pub Date : 2025-07-11 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0228

Rafael Thomazi, Carlos Alberto Dos Santos, Alessandro Ferrari Jacinto

{"title":"Factors associated with psychotropic drugs use in older adults hospitalized in clinical and surgical wards of a university hospital.","authors":"Rafael Thomazi, Carlos Alberto Dos Santos, Alessandro Ferrari Jacinto","doi":"10.1590/1980-5764-DN-2024-0228","DOIUrl":"10.1590/1980-5764-DN-2024-0228","url":null,"abstract":"Prescription of psychotropic drugs and potentially inappropriate medications (PIMs) for older adults is a common condition. Assessing the factors associated with this prescription is essential especially within the hospital setting, requiring the implementation of strategies for promoting rational use of medications in this age group.Objective: To evaluate factors associated with the use of psychotropic drugs in hospitalized older adults.Methods: Cross-sectional study, conducted at Hospital das Clínicas de Botucatu, Brazil. Patients were divided into clinical patients taking or not taking psychotropic drugs and surgical patients taking or not taking psychotropic drugs. Multivariate analysis was performed, adopting \"use or non-use of psychotropic drugs\" and \"having geriatrician as prescriber before hospitalization or otherwise\", as dependent variables.Results: Of the 385 participants, 60% practiced polypharmacy and 55% were in use of PIM. Clinical patients using psychotropic drugs took more PIM (p<0.001) and more medications (p=0.002) than non-users. For the total sample, PIM use was associated with a 4.53 times greater chance of taking psychotropic drugs, and each additional medication used was associated with a 1.15 times greater chance of taking psychotropic drugs. Being accompanied by a geriatrician before hospital admission was associated with a 4.0 times greater chance of no PIM being prescribed.Conclusion: PIM use and polypharmacy were associated with an increased chance of taking psychotropic drugs. Being accompanied by a geriatrician before hospitalization was associated with a lower chance of PIM use.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240228"},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Economic evaluation of non-pharmacological interventions in Alzheimer's disease. 阿尔茨海默病非药物干预的经济评价。

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0219

Margarida Sobral, Susana Oliveira

{"title":"Economic evaluation of non-pharmacological interventions in Alzheimer's disease.","authors":"Margarida Sobral, Susana Oliveira","doi":"10.1590/1980-5764-DN-2024-0219","DOIUrl":"10.1590/1980-5764-DN-2024-0219","url":null,"abstract":"Alzheimer's disease (AD) has significant physical, psychological, and socioeconomic impacts, shortens life expectancy, and reduces quality of life. Non-pharmacological interventions (NPIs) in dementia provide health gains.Objective: The aim of this study was to conduct a cost-utility study of NPIs in AD, assessing both the costs and health gains associated with cognitive stimulation interventions in AD patients.Methods: A sample of 40 patients undergoing NPIs and another 40 individuals (control group) were included. Data collected included sociodemographic, clinical, cognitive, and functional information, as well as health status, quality of life, and outpatient costs.Results: The NPI, considering the discounted cost value of €21,621.31 and the discounted quality-adjusted life year (QALY) gain of 0.81333, resulted in an estimated cost per QALY of €26,583.76. This cost per QALY is within the threshold generally considered acceptable by regulatory authorities in Portugal and in several European countries.Conclusion: This study supports the recommendation that interventions adjusted to the needs of patients with AD should be implemented, which may include NPIs providing both health gains and economic value.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240219"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroplasticity in autism spectrum disorder: a systematic review. 自闭症谱系障碍的神经可塑性：一项系统综述。

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0182

Gabriela Garcia de Carvalho Laguna, Ana Beatriz Ferreira Gusmão, Breno Oliveira Marques, Níkolas Brayan da Silva Bragas, Isadora Bagues Rodrigues, Rafaela Souza Melo, Katiene Rodrigues Menezes de Azevedo

{"title":"Neuroplasticity in autism spectrum disorder: a systematic review.","authors":"Gabriela Garcia de Carvalho Laguna, Ana Beatriz Ferreira Gusmão, Breno Oliveira Marques, Níkolas Brayan da Silva Bragas, Isadora Bagues Rodrigues, Rafaela Souza Melo, Katiene Rodrigues Menezes de Azevedo","doi":"10.1590/1980-5764-DN-2024-0182","DOIUrl":"10.1590/1980-5764-DN-2024-0182","url":null,"abstract":"The brain's ability to adapt in response to stimuli is called neuroplasticity.Objective: This study investigates neuroplasticity in autistic individuals, focusing on neurobiological aspects, clinical correlations, and therapeutic interventions.Methods: This systematic review, registered in the International Prospective Register of Systematic Reviews-PROSPERO (ID: CRD42024522425) and guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses-PRISMA (2020) criteria, searched databases like Web of Science, Scopus, United States National Library of Medicine/ Medical Literature Analysis and Retrieval System Online (PubMed/Medline), Latin American and Caribbean Health Sciences Literature (LILACS), and Scientific Electronic Library Online (SciELO) for original articles published in 2018-2023.Results: Of the 2,316 studies found, 11 were selected, involving 1,943 autistic individuals, both children and adults. Most studies were classified as high/moderate quality using the Newcastle-Ottawa and Jadad scales. Observations included variations in SHANK2 gene expression, lower concentrations of α-synuclein, higher β-synuclein in children with autism spectrum disorder (ASD), correlations between NCAM1 expression and motor skills, and higher brain-derived neurotrophic factor (BDNF) concentration compared to non-autistic children.Conclusions: Alterations in SHANK2, α-synuclein, β-synuclein, NCAM1, and BDNF in ASD suggest biomarkers and therapeutic targets for more effective interventions, improving care for autistic individuals.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240182"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with family caregiver burden of patients with dementia. 痴呆患者家庭照顾者负担的相关因素。

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0190

Andressa Hermes-Pereira, Mariana Goulart, Renata Kochhann, Artur Francisco Schumacher-Schuh

{"title":"Factors associated with family caregiver burden of patients with dementia.","authors":"Andressa Hermes-Pereira, Mariana Goulart, Renata Kochhann, Artur Francisco Schumacher-Schuh","doi":"10.1590/1980-5764-DN-2024-0190","DOIUrl":"10.1590/1980-5764-DN-2024-0190","url":null,"abstract":"Neuropsychiatric symptoms of dementia, also known as behavioral and psychological symptoms of dementia, are extremely common. These symptoms represent one of the main causes of burden and distress among caregivers and can lead to decline in their physical and mental health.Objective: This study aimed to identify predominant characteristics in a sample of Brazilian outpatient dementia patients and explore which symptoms exert the greatest influence on caregiver burden.Methods: This was a cross-sectional study involving 119 caregivers. Stepwise regression analysis was used, with caregiver burden as the dependent variable and depressive symptoms, caregiver distress due to neuropsychiatric symptoms, and quality of life as independent variables in the final model.Results: Regression analysis identified three different models as predictors of caregiver burden. The first model, composed of depressive symptoms, predicted 34% of caregiver burden (p≤0.000). The second model, composed of depressive symptoms and caregiver distress due to neuropsychiatric symptoms, predicted 49% (p≤0.000). The third model, composed of depressive symptoms, caregiver distress due to neuropsychiatric symptoms, and quality of life, predicted 52% (p≤0.008).Conclusion: Our findings indicate that problematic behaviors in dementia patients, depressive symptoms, and quality of life are associated with the level of caregiver burden and distress. Further research is needed to differentiate these findings among different types of dementia and to better understand how caregivers' individual characteristics influence their own burden.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240190"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Loneliness during the COVID-19 pandemic: A potential risk factor for post-pandemic cognitive decline in older adults without dementia. COVID-19大流行期间的孤独：无痴呆症老年人大流行后认知能力下降的潜在危险因素

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0256

Alaa Harb, Juliana Nery Souza-Talarico, Grace Willey, Fernanda Carini da Silva, Maria Clara Ferreira de Jesus, Jennifer Deberg

{"title":"Loneliness during the COVID-19 pandemic: A potential risk factor for post-pandemic cognitive decline in older adults without dementia.","authors":"Alaa Harb, Juliana Nery Souza-Talarico, Grace Willey, Fernanda Carini da Silva, Maria Clara Ferreira de Jesus, Jennifer Deberg","doi":"10.1590/1980-5764-DN-2024-0256","DOIUrl":"10.1590/1980-5764-DN-2024-0256","url":null,"abstract":"The COVID-19 pandemic has exacerbated loneliness and social isolation among older adults, raising concerns about their mental and physical well-being. While loneliness's adverse effects on health are well-documented, its specific impact on cognitive health during the pandemic remains under investigation.Objective: The aim of this study was to examine the association between loneliness during the COVID-19 pandemic and cognitive decline in cognitively unimpaired older adults by synthesizing evidence from primary studies.Methods: A comprehensive search strategy was employed across multiple databases, including MEDLINE (PubMed), CINAHL (EBSCO), PsycINFO (EBSCO), EMBASE, Scopus, AgeLine, and ProQuest, following PRISMA guidelines. Studies were selected to examine the association between loneliness and cognitive function in cognitively unimpaired older adults (aged ≥50 years) during the COVID-19 pandemic.Results: A total of eight studies were included from 1,384 search results, reviewing data from 10,449 cognitively unimpaired older adults. A total of six studies found significant associations between loneliness or social isolation and subjective cognitive decline (SCD). Only one study linked loneliness to lower objective cognitive performance. Notably, half of the studies considered key covariates, such as depression, which could mediate the relationship between loneliness and cognitive decline.Conclusion: Loneliness during the COVID-19 pandemic is linked to SCD in older adults, though objective evidence is limited. The pandemic underscored the long-term impact of social isolation on cognition and mental health, highlighting the need for standardized neuropsychological tools and key covariates in studies to identify those at risk.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240256"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychometric evaluation of the Brief Cognitive Screening Battery: Indonesian version. 简短认知筛选电池的心理测量评估：印尼语版。

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0250

Fasihah Irfani Fitri, Dina Nazriani, Octaviasari Agatha Dachi, Ricardo Nitrini, Paulo Caramelli

{"title":"Psychometric evaluation of the Brief Cognitive Screening Battery: Indonesian version.","authors":"Fasihah Irfani Fitri, Dina Nazriani, Octaviasari Agatha Dachi, Ricardo Nitrini, Paulo Caramelli","doi":"10.1590/1980-5764-DN-2024-0250","DOIUrl":"10.1590/1980-5764-DN-2024-0250","url":null,"abstract":"Dementia is a significant public health challenge, particularly in low- and middle-income countries such as Indonesia, where underdiagnosis is common.Objective: To investigate the psychometric properties of the Brief Cognitive Screening Battery - Indonesian Version (BCSB-INA), a culturally-adapted tool aimed at improving the early detection of dementia.Methods: The tool was tested on a sample of 140 older adults, covering various cognitive domains through multiple subscales. Data were analyzed using bootstrap resampling, Kaiser-Meyer-Olkin (KMO) test, Confirmatory Factor Analysis (CFA), and reliability assessments such as Cronbach's Alpha.Results: The overall reliability, measured by Cronbach's Alpha, was high (α=0.968). The KMO test yielded a value of 0.889, indicating sample adequacy for factor analysis. The CFA indicated that most dimensions achieved satisfactory validity, with the majority of items demonstrating acceptable factor loadings.Conclusions: BCSB-INA has demonstrated good reliability and validity throughout its dimensions, suggesting its applicability for use in cognitive assessments in the Indonesian context.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240250"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in the diagnosis and management of depressive and cognitive disorders in older adults: a case report. 老年人抑郁和认知障碍诊断和管理的挑战：一份病例报告。

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2025-0295

Nour Regaieg, Dorra Mnif, Emna Smaoui, Fatma Guermazi, Salma Sakka, Ines Feki, Imen Baâti, Jawaher Masmoudi

{"title":"Challenges in the diagnosis and management of depressive and cognitive disorders in older adults: a case report.","authors":"Nour Regaieg, Dorra Mnif, Emna Smaoui, Fatma Guermazi, Salma Sakka, Ines Feki, Imen Baâti, Jawaher Masmoudi","doi":"10.1590/1980-5764-DN-2025-0295","DOIUrl":"10.1590/1980-5764-DN-2025-0295","url":null,"abstract":"Dementia with Lewy Bodies and depression are two common conditions in older adults that can share clinical similarities or coexist. We aim to highlight the diagnostic and therapeutic challenges of these two pathologies through the case of Mrs. S., a 67-year-old patient admitted to the psychiatric department for agitation and insomnia. Her symptoms initially presented as depression, followed by severe agitation. In the admission interview, we observed an anxious patient with bradyphemia, primarily focused on well-detailed visual hallucinations related to death. Upon neurological examination, we identified Parkinsonian syndrome. The patient was treated with quetiapine 200 mg/day and sertraline 50 mg/day, leading to a marked improvement in both depressive and Parkinsonian symptoms. Ultimately, the diagnosis was a major depressive episode with psychotic and melancholic features as part of a bipolar II disorder. In neuropsychiatric presentations of dementia with Lewy Bodies, cognitive and neurological evaluations should always be considered. In some cases, clinical evolution remains the only means of distinguishing between depression and dementia with Lewy Bodies.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20250295"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent transient global amnesia related to dural arteriovenous fistula. 复发性短暂性全身性遗忘与硬脑膜动静脉瘘的关系。

Dementia e Neuropsychologia Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1980-5764-DN-2024-0222

Rafael Batista João, Raquel Filgueiras Mattos

引用次数: 0