Japanese Journal of Head and Neck Cancer最新文献_第6页

Discriminate potential of VTIQ between malignant tumor and benign salivary gland tumor by propagation velocity and tissue elasticity image VTIQ在恶性肿瘤和良性唾液腺肿瘤之间的传播速度和组织弹性图像鉴别潜力

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/JJHNC.47.30

T. Matsuzuka, Tetsuro Kobayashi, Masahiro Suzuki, Y. Nakaegawa, Tomotaka Kawase, Y. Hasegawa, S. Murono

{"title":"Discriminate potential of VTIQ between malignant tumor and benign salivary gland tumor by propagation velocity and tissue elasticity image","authors":"T. Matsuzuka, Tetsuro Kobayashi, Masahiro Suzuki, Y. Nakaegawa, Tomotaka Kawase, Y. Hasegawa, S. Murono","doi":"10.5981/JJHNC.47.30","DOIUrl":"https://doi.org/10.5981/JJHNC.47.30","url":null,"abstract":"Discriminate potential of VTIQ between malignant tumor and benign salivary gland tumor by propagation Virtual touch tissue imaging quantiﬁcation （VTIQ） is an elastography technique that measures the tissue elasticity quantitatively as the propagation velocity （Vs） of shear waves and displays tissue elasticity images. We analyzed the histological relationship of 51 salivary gland tumors whose VTIQ was measured and pathologi-cally diagnosed from 2016 to 2019 at Fukushima Medical University Hospital. There were 11 malignant tumors, 21 benign tumors with pleomorphic adenoma, and 19 other benign tumors, and Vs and tissue elasticity images were compared among the three groups. Vs of 4.8m/s or higher was 45％ overall, 91％ for malignant tumors, 55％ for pleomorphic adenomas, and 0％ for other benign tumors. Vs for pleomorphic adenomas had a large range and was diﬃcult to distinguish from that for malignant tumors. The tissue elasticity images of each tumor were classiﬁed into four types: 91％ of malignant tumors and 10％ of pleomorphic adenomas were the homogeneous type or geographic type, and 9％ of malignant tumors and 67％ of pleomorphic adenomas were the mottled type. Although it was diﬃcult to discriminate by Vs, it may be possible to discriminate between malignant tumors and pleomorphic adenomas by tissue elasticity images.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of basal cell adenocarcinoma of the hard palate which progressed to the cheek 硬腭基底细胞腺癌进展至面颊1例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.353

Tsuyoshi Takemoto, H. Orita, Y. Okazaki, R. Murakami, Ritsuko Miyauchi

引用次数: 0

Long-term change in the oral health related QOL of patients treated with definitive radiotherapy for head and neck cancer 头颈癌放疗患者口腔健康相关生活质量的长期变化

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.290

K. Jingu, N. Takahashi, S. Tasaka, R. Umezawa, Takaya Yamamoto, Y. Ishikawa, K. Takeda, Yu Suzuki, N. Kadoya, H. Matsushita

{"title":"Long-term change in the oral health related QOL of patients treated with definitive radiotherapy for head and neck cancer","authors":"K. Jingu, N. Takahashi, S. Tasaka, R. Umezawa, Takaya Yamamoto, Y. Ishikawa, K. Takeda, Yu Suzuki, N. Kadoya, H. Matsushita","doi":"10.5981/jjhnc.47.290","DOIUrl":"https://doi.org/10.5981/jjhnc.47.290","url":null,"abstract":"Long-term Xerostomia is one of the most common adverse events of radiotherapy （RT） in head and neck cancer patients. The salivary glands are highly sensitive to and damaged by radiation, leading to xerostomia, which de-creases patientsʼ quality of life （QOL） after radiotherapy. The purpose of this study was to evaluate long-term changes of oral health related QOL after deﬁnitive RT. Patients who were treated by RT with 60Gy or more for head and neck cancer were analyzed retrospectively. Patients with recurrence were excluded. Oral health related QOL was assessed with the General Oral Health Assessment Index （GOHAI） at follow-up dates. Sixty-six patients without recurrence were enrolled in this study. Oral health related QOL decreased rapidly during RT and recovered to the same level as normal in 3-3.5 months after the completion of RT. The nadir of GOHAI score appeared immediately after radiotherapy and the score had recovered signiﬁcantly in all periods. There was no signiﬁcant difference in changes in oral related QOL after RT between patients with a mean irradiated dose to the bilateral parotid glands of less than 35Gy and those of 35Gy or more.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A case of a malignant peripheral nerve sheath tumor on the cheek following trauma 创伤后面颊恶性周围神经鞘肿瘤1例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.388

R. Aijima, Keisuke Mori, A. Danjo, Mitsutoshi Ohishi, R. Egashira, Yuichi Yamada, Hiroyuki Irie, Y. Oda, S. Aishima, Y. Yamashita

引用次数: 0

Clinicopathological study on local recurrence of primary oral squamous cell carcinoma 原发性口腔鳞状细胞癌局部复发的临床病理研究

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/JJHNC.47.35

A. Abe, Yu Ito, Hiroki Hayashi, Takanori Ishihama, H. Furuta, Hiroshi Horibe, K. Tange

引用次数: 0

A case of treatment related death caused by mucosal necrosis, brain necrosis and osteonecrosis after carbon ion radiotherapy in nasopharyngeal adenoid cystic carcinoma 鼻咽腺样囊性癌碳离子放疗后黏膜坏死、脑坏死、骨坏死致治疗相关性死亡1例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/JJHNC.47.71

Yusuke Nakata, Y. Demizu, T. Okimoto, Takeshi Shimizu

引用次数: 0

Cochlear implantation for bilateral severe hearing loss after a single administration of cisplatin: A case report 单次顺铂治疗双侧重度听力损失的人工耳蜗植入一例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/JJHNC.47.78

S. Kinoshita, M. Hara, Kazuhiro Mitsumura, M. Ōsaki, Eikichi Tokunaga, Akio Hatanaka, W. Nishijima

{"title":"Cochlear implantation for bilateral severe hearing loss after a single administration of cisplatin: A case report","authors":"S. Kinoshita, M. Hara, Kazuhiro Mitsumura, M. Ōsaki, Eikichi Tokunaga, Akio Hatanaka, W. Nishijima","doi":"10.5981/JJHNC.47.78","DOIUrl":"https://doi.org/10.5981/JJHNC.47.78","url":null,"abstract":"We encountered a patient who underwent cochlear implant surgery for bilateral severe hearing loss after administration of cisplatin. The patient was a 69-year-old man who received cisplatin and vinorelbine as post-operative chemotherapy for lung cancer. On day 7 of administration, the patient experienced hearing loss. On day 9, pure tone audiometry showed bilateral deafness. The patient also developed a renal disorder, but it subsequently improved. As hearing aids were ineffective, cochlear implantation was performed to treat the bilateral severe hearing loss. The patientʼs hearing ability was favorable immediately after the implantation. This case shows that hearing loss can be induced by cisplatin after not only dose accumulation but also single administration. Identifying genes related to cisplatin-induced hearing loss to predict post-administration hearing can contribute to a safer cancer treatment plan. Currently, there is no method for predicting or preventing the onset of hearing loss; therefore, cochlear implant surgery may be the only option for patients who develop bilateral severe hearing loss after the ﬁrst administration of cisplatin.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The clinical utility of comprehensive genomic profiling for recurrent / metastatic head and neck cancer 综合基因组图谱在复发/转移性头颈癌中的临床应用

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.359

Kohki Tohyama, Y. Kano, Rika Noji, Yasuko Aoyagi, Shotaro Matsudera, K. Ohno, Yosuke Ariizumi, Y. Michi, H. Tomioka, H. Shimamoto, R. Yoshimura, T. Asakage, H. Harada, S. Miyake, M. Miura, S. Ikeda

{"title":"The clinical utility of comprehensive genomic profiling for recurrent / metastatic head and neck cancer","authors":"Kohki Tohyama, Y. Kano, Rika Noji, Yasuko Aoyagi, Shotaro Matsudera, K. Ohno, Yosuke Ariizumi, Y. Michi, H. Tomioka, H. Shimamoto, R. Yoshimura, T. Asakage, H. Harada, S. Miyake, M. Miura, S. Ikeda","doi":"10.5981/jjhnc.47.359","DOIUrl":"https://doi.org/10.5981/jjhnc.47.359","url":null,"abstract":"要旨頭頸部癌患者 14 例 18 件に対し FoundationOne CDx などのがん遺伝子パネル検査を使用し,組織検体 15 件(83.3%),血液検体 3 件(16.6%)における遺伝子変異の解析を行った。原発部位別では,舌癌が 6 例(42.8%) と最多で,検出された遺伝子変異としては TP53,TERT promoter,CDKN2A などであり,全ゲノム解析を用いた既報と矛盾しない結果となった。14 例のうち,治療候補があった症例は 11 例(78.6%)であったが, 実際に遺伝子パネル検査に基づいて治療を行った症例は 2 例(14.3%)であり治療薬へのアクセス率の向上が今後の課題となった。また,TMB(Tumor Mutational Burden)が高値を示した 3 症例のうち 2 例で免疫チェックポイント阻害剤による奏効が得られ,TMB が頭頸部癌の実臨床における新たなバイオマーカーとして有用である可能性が示唆された。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hybrid cadaver training with holograms by mixed reality technique 混合现实技术的全息混合尸体训练

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.366

Kayo Sakamoto, Sohei Mitani, Eriko Sato, Takashi Kitani, Tomoyoshi Sanada, N. Hato

引用次数: 0

82 cases of laryngeal preservation surgery for laryngeal cancer 喉保留手术治疗喉癌82例分析

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.371

Katsuji Asano, Y. Somekawa, K. Takano, M. Kurose, Shigeru Koshiba, Yousuke Nagai, M. Myoujin, Hikaru Ikeda, M. Nishio

{"title":"82 cases of laryngeal preservation surgery for laryngeal cancer","authors":"Katsuji Asano, Y. Somekawa, K. Takano, M. Kurose, Shigeru Koshiba, Yousuke Nagai, M. Myoujin, Hikaru Ikeda, M. Nishio","doi":"10.5981/jjhnc.47.371","DOIUrl":"https://doi.org/10.5981/jjhnc.47.371","url":null,"abstract":"The author performed larynx-conserving surgery on a total of 82 patients （59 primary cases and 23 secondary cases） of laryngeal cancer. The disease-speciﬁc 5-year survival rate of all 82 patients was 92.6％. The larynx con-servation rate was 87.8％ in all 82 cases. In regard to the treatment of early-stage laryngeal cancer （T1, 2）, we suggested that larynx-conserving surgery should be considered as an option for initial treatment because it is not inferior to radiotherapy in terms of clinical outcome and preservation of laryngeal function in daily life. Larynx-conserving surgery as a salvage treatment for recurrence did not present a lower laryngeal preservation rate than for primary cases, and seemed to be an eﬀective method of salvage surgery for recurrent patients. these 11 cases, 5 cases whose surgical margins were diagnosed as negative on histopathological examination suﬀered local recurrence. We performed total laryngectomy as a salvage surgery on these 5 cases. Of the 16 cases of locally advanced cancer （T3, 4）, 5 cases （1 case of deep tongue muscle invasion, 3 cases of anterior invasion of the epiglottis, and 1 case of anterior wall invasion of the cricoid cartilage） showed no local recurrence and local control was successfully achieved with surgery alone. Regarding indications, in the case of locally advanced laryngeal cancer involving anterior invasion of the epiglottis, deep tongue muscle invasion, and anterior wall invasion of the cricoid cartilage, larynx-conserving surgery appropriately indicated because the cases were local controlled with surgery alone. However, in the case of recurrence, postoperative radiotherapy should be considered because of the diﬃculty of preserving the function of the larynx.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0