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Japanese Journal of Head and Neck Cancer最新文献

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ラロトレクチニブが著効した唾液腺分泌癌の1例 拉罗特瓣起效的唾液腺分泌癌的一例
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.26
Hayato Fukuzono, B. Nishimura, Shinji Oyama, Shin Matsumoto, M. Nakayama, K. Takahashi
{"title":"ラロトレクチニブが著効した唾液腺分泌癌の1例","authors":"Hayato Fukuzono, B. Nishimura, Shinji Oyama, Shin Matsumoto, M. Nakayama, K. Takahashi","doi":"10.5981/jjhnc.49.26","DOIUrl":"https://doi.org/10.5981/jjhnc.49.26","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
当科における頭頸部癌自家遊離組織移植術症例の術後合併症と対策 本科室头颈癌自体游离组织移植术病例的术后并发症及对策
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.1
Takuma Morita, Akira Seto, H. Mitani, H. Fukushima, T. Sasaki, W. Shimbashi, Y. Koizumi, R. Kamiyama, Kazunori Ichikawa, Junichi Torii, Kosuke Hihara, H. Iwaki, Kohei Saijo, Yuki Matsui, Sae Imaizumi, Yuki Kayo, Takeki Yagi
{"title":"当科における頭頸部癌自家遊離組織移植術症例の術後合併症と対策","authors":"Takuma Morita, Akira Seto, H. Mitani, H. Fukushima, T. Sasaki, W. Shimbashi, Y. Koizumi, R. Kamiyama, Kazunori Ichikawa, Junichi Torii, Kosuke Hihara, H. Iwaki, Kohei Saijo, Yuki Matsui, Sae Imaizumi, Yuki Kayo, Takeki Yagi","doi":"10.5981/jjhnc.49.1","DOIUrl":"https://doi.org/10.5981/jjhnc.49.1","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on the treatment outcomes of advanced laryngeal and hypopharyngeal cancer with induction chemotherapy 晚期喉癌和下咽癌诱导化疗治疗效果的研究
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.249
Hideoki Uryu, Shingo Tamura, Rina Kitagawa, Ayaka Koide, Kaori Hara, Ryutaro Uchi, Torahiko Nakashima
{"title":"Study on the treatment outcomes of advanced laryngeal and hypopharyngeal cancer with induction chemotherapy","authors":"Hideoki Uryu, Shingo Tamura, Rina Kitagawa, Ayaka Koide, Kaori Hara, Ryutaro Uchi, Torahiko Nakashima","doi":"10.5981/jjhnc.49.249","DOIUrl":"https://doi.org/10.5981/jjhnc.49.249","url":null,"abstract":"頭頸部癌の標準的なCDDP併用化学放射線治療（CCRT）の前治療として，DTX＋CDDP＋5-FU（TPF）を用いた導入化学療法（ICT）の有用性が報告されているが，ICTは有害事象も多く，その効果については議論が分かれる。我々は喉頭温存希望のある進行喉頭癌，下咽頭癌30症例を対象に，ICTとそれに引き続くCCRTについて，完遂率，原発巣（T）・頸部リンパ節転移（N）別の奏功率，予後，喉頭温存について検討を行った。喉頭が9例（Stage Ⅲ：4例，Stage Ⅳ：5例），下咽頭が21例（Stage Ⅲ：3例，Stage Ⅳ：18例）。ICT（TPF2クール）の完遂率は93％，ICT＋CCRTの完遂率は82％，ICTの奏功率はT100％，N80％，ICT＋CCRTの奏功率はT97％，N92％，2年の全生存率は75％，2年喉頭温存生存率は67％と良好な成績であった。今回の検討から，症例を選択し，有害事象の対応を行えばTPFによるICT，CCRTでも良好な完遂，効果を得られると考える。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135705443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical evaluation of 15 cases of multiple oral cancers with special reference to coexisting oral potentially malignant disorders 多发性口腔癌15例临床评价，并以并发口腔潜在恶性疾病为例
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.9
Ayaka Abe, Tatsuyuki Kono, K. Kawano
{"title":"Clinical evaluation of 15 cases of multiple oral cancers with special reference to coexisting oral potentially malignant disorders","authors":"Ayaka Abe, Tatsuyuki Kono, K. Kawano","doi":"10.5981/jjhnc.49.9","DOIUrl":"https://doi.org/10.5981/jjhnc.49.9","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
喉頭摘出術を併施した頸部食道癌例 配合喉切除术的颈部食道癌病例
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.262
Akihiro Murashima, Daisuke Kawakita, Takuma Matoba, Gaku Takano, Keisuke Oguri, Kiyoshi Minohara, Sho Iwaki, Hiroshi Tsuge, Sae Imaizumi, Ayano Kondo, Koji Tsukamoto, Tatsuya Tanaka, Ryo Ogawa, Shinichi Iwasaki
{"title":"喉頭摘出術を併施した頸部食道癌例","authors":"Akihiro Murashima, Daisuke Kawakita, Takuma Matoba, Gaku Takano, Keisuke Oguri, Kiyoshi Minohara, Sho Iwaki, Hiroshi Tsuge, Sae Imaizumi, Ayano Kondo, Koji Tsukamoto, Tatsuya Tanaka, Ryo Ogawa, Shinichi Iwasaki","doi":"10.5981/jjhnc.49.262","DOIUrl":"https://doi.org/10.5981/jjhnc.49.262","url":null,"abstract":"頸部食道癌は全食道癌の約5％の希少疾患である。頭側への進展例では喉頭摘出が必要となり，頸部リンパ節転移例も多いことから，頭頸部外科の重要性が高い。名古屋市立大学病院では喉頭摘出・頸部郭清術を必要とする症例は頭頸部外科が頸部操作を行う。今回2017年から2022年までに，当院にて手術加療を行った頸部食道がん25例のうち，喉頭合併切除を要した15例を対象に後方視的検討を行った。年齢中央値は69歳，男性12例，女性3例であった。全症例が扁平上皮癌で，臨床病期はステージIが2例，ステージⅡが5例，ステージⅢが7例，ステージⅣaが1例であった。15例のうち7例は頸部操作のみで摘出可能であった。2年全生存率は33.3％，無病生存率は33.3％であった。術後合併症は9例で認め，気管壊死が1例に生じ処置を必要とした。頸部食道がんの治療には頭頸部外科・消化器外科の協力が重要である。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135705187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
頭頸部癌治療後患者の嚥下障害に対する外科的介入について 关于颈部癌症治疗后患者吞咽困难的外科干预
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.15
Mayu Yamauchi, Toshihide Inagi, Aritomo Yamazaki, Hiroaki Iijima, Koji Ebisumoto, Akihiro Sakai, Koichiro Nishiyama, Kenji Okami
{"title":"頭頸部癌治療後患者の嚥下障害に対する外科的介入について","authors":"Mayu Yamauchi, Toshihide Inagi, Aritomo Yamazaki, Hiroaki Iijima, Koji Ebisumoto, Akihiro Sakai, Koichiro Nishiyama, Kenji Okami","doi":"10.5981/jjhnc.49.15","DOIUrl":"https://doi.org/10.5981/jjhnc.49.15","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphoepithelial carcinoma of the parotid gland 腮腺淋巴上皮癌
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.273
Kazutaka Takeuchi, Daiki Mochizuki, Kotaro Morita, Satoshi Yamada, Atsushi Imai, Yoshinori Takizawa, Kiyoshi Misawa
{"title":"Lymphoepithelial carcinoma of the parotid gland","authors":"Kazutaka Takeuchi, Daiki Mochizuki, Kotaro Morita, Satoshi Yamada, Atsushi Imai, Yoshinori Takizawa, Kiyoshi Misawa","doi":"10.5981/jjhnc.49.273","DOIUrl":"https://doi.org/10.5981/jjhnc.49.273","url":null,"abstract":"唾液腺原発のリンパ上皮癌は，全唾液腺癌の1％未満を占める稀な腫瘍であり，Epstein-Barr virus（EBV）の関連が示唆されている。今回われわれは，稀なEBV非関連の耳下腺リンパ上皮癌症例を経験した。症例は69歳男性，近医総合病院耳鼻咽喉科で耳下腺浅葉切除術を施行され，耳下腺リンパ上皮癌の診断となった。追加治療目的に当院へ紹介となり，術後の画像検査で頸部リンパ節転移を認めたため，左全頸部郭清術を施行した。複数の頸部リンパ節転移を認め，節外浸潤を伴っていたため，後治療として放射線治療を施行した。治療後3年経過しているが再発，転移は認めていない。リンパ上皮癌は放射線感受性が高いことが知られており，術後に放射線治療を行うことで，予後を改善する可能性がある。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135703739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
腎細胞癌の甲状腺転移とそれに伴う静脈内腫瘍塞栓に対しTransmanubrial Osteomuscular Sparing Approachで静脈再建を施行した1例 Transmanubrial Osteomuscular Sparing Approach对肾细胞癌的甲状腺转移及其导致的静脉内肿瘤栓塞实施静脉重建的1例
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.31
Shino Godo, Shuji Koike, Yutaka Ohsawa
{"title":"腎細胞癌の甲状腺転移とそれに伴う静脈内腫瘍塞栓に対しTransmanubrial Osteomuscular Sparing Approachで静脈再建を施行した1例","authors":"Shino Godo, Shuji Koike, Yutaka Ohsawa","doi":"10.5981/jjhnc.49.31","DOIUrl":"https://doi.org/10.5981/jjhnc.49.31","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
頭頸部外科医が施行した頭頸部再建術におけるマイクロサージャリー104例の治療成績と合併症の分析 分析头颈外科医生实施的头颈重建术中104例微查术的治疗成绩和并发症
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.255
Takashi Matsuki, Shunsuke Miyamoto, Koichi Kano, Shohei Tsutsumi, Kaho Momiyama, Taku Yamashita
{"title":"頭頸部外科医が施行した頭頸部再建術におけるマイクロサージャリー104例の治療成績と合併症の分析","authors":"Takashi Matsuki, Shunsuke Miyamoto, Koichi Kano, Shohei Tsutsumi, Kaho Momiyama, Taku Yamashita","doi":"10.5981/jjhnc.49.255","DOIUrl":"https://doi.org/10.5981/jjhnc.49.255","url":null,"abstract":"遊離組織による頭頸部再建術は，創部治癒，形態保持，機能温存において有用である。当科では遊離組織の採取と再建も頭頸部外科医が行っており，104例（106皮弁）におけるマイクロサージャリーを検討した。口腔と下咽頭の再建が多く，再建材料は前外側大腿皮弁（ALT）が約半数と最多であった。移植床の血管は上甲状腺動脈と内頸静脈が大半で選択されていた。術中の遊離組織トラブルは14例（13％）で生じ，8例が動脈吻合部血栓であった。術後の遊離組織トラブルは6例（6％）で生じ，4例（4％）で皮弁を除去していた。術後に吻合部血栓はなかったがALTの穿通枝トラブルが4例と多かった。術中トラブルは二次治療に多い傾向があり（P＝0.059），術後トラブルは術後感染と関連していた（P＝0.016）。過去の報告と比較しても劣らない成績であったが，特にALTの穿通枝の扱いに関して改善の余地を認めた。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135705195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pembrolizumabによる関節炎を制御しながら治療継続できた再発転移喉頭癌の1例 一个复发转移喉癌病例，在控制关节炎的同时继续治疗。
Japanese Journal of Head and Neck Cancer Pub Date : 2023-01-01 DOI: 10.5981/jjhnc.49.278
Nanae Kaneta, Takashi Matsuki, Shunsuke Miyamoto, Taku Yamashita
{"title":"Pembrolizumabによる関節炎を制御しながら治療継続できた再発転移喉頭癌の1例","authors":"Nanae Kaneta, Takashi Matsuki, Shunsuke Miyamoto, Taku Yamashita","doi":"10.5981/jjhnc.49.278","DOIUrl":"https://doi.org/10.5981/jjhnc.49.278","url":null,"abstract":"76歳男性。喉頭癌術後の頸部，肺転移に対してPembrolizumab単剤療法を行った。初回投与の2日後にCTCAE Grade 2の関節炎を発症した。免疫関連有害事象 （irAE） と診断し，Prednisolone 20mgから投与を開始し，速やかに症状および血液検査所見の改善を認めた。その後はPrednisoloneを漸減しながら，irAEの再燃なくPembrolizumabの投与を継続することができた。irAEとしての関節炎の報告は多くないが，Grade 2以上であると日常生活に影響を及ぼし，免疫チェックポイント阻害薬 （ICI）を中断・中止せざるを得ないこともある。しかし，irAEの発症とICIの有効性が関連するとの報告もあり，本症例でも縮小を維持している。複数の診療科と連携し，irAEを制御しながらICIを継続できることは，この症例の長期生存に寄与できると考えている。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135705455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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