Japanese Journal of Head and Neck Cancer最新文献_第5页

An interim analysis of malnutrition and prognosis in elderly head and neck cancer patient: Koto-SG multicenter research 老年头颈癌患者营养不良与预后的中期分析:Koto-SG多中心研究

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.329

A. Arai, Nariyasu Ishizaka, N. Tadaki, Rei Murakami, Hitosuke Tameno, K. Kayano, K. Tei, S. Koike, K. Nobuhara, H. Okano, Hiroki Morimoto, G. Omura, T. Tsujikawa, Y. Sugiyama, S. Hirano

引用次数: 0

Comparison of trans oral surgery and partial pharyngectomy with primary closure for early stage hypopharyngeal cancer 早期下咽癌经口手术与部分咽切除术一期闭合的比较

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.267

Toshifumi Tomioka, K. Matsuura, Y. Morishita, W. Okano, T. Shinozaki, T. Yano, R. Hayashi

{"title":"Comparison of trans oral surgery and partial pharyngectomy with primary closure for early stage hypopharyngeal cancer","authors":"Toshifumi Tomioka, K. Matsuura, Y. Morishita, W. Okano, T. Shinozaki, T. Yano, R. Hayashi","doi":"10.5981/jjhnc.47.267","DOIUrl":"https://doi.org/10.5981/jjhnc.47.267","url":null,"abstract":"Background: Recent developments in transoral surgery （TOS） have improved outcomes in early-stage hypopharyngeal cancer. To date, however, indications for TOS and partial pharyngectomy with primary closure （PP-PC）, which is also used in these early-stage diseases, have not been considered in detail. Here, we investigated whether TOS could be used as minimally invasive surgery while maintaining outcomes comparable to those of PP-PC. Methods: This was a single-center retrospective case control study. Median follow-up period was 59.4 months （1.2-174） for TOS and 88.8 months （3.6-158.4） for PP-PC. Patients who received initial surgical treatment for hypopharyngeal cancer were recruited from 2002 through 2014. Among these patients who underwent TOS or PP-PC, cT1-3N0M0 was included. Those with histopathological invasion of the muscularis propria were excluded. Of 117 consecutive cases, 87 cases were treated with TOS and 30 with PP-PC. Median age was 66 years （42-88）. Lesions were in the pyriform sinus （PS） in 91 cases, posterior wall （PW） in 18, and postcricoid area （PC） in 8. cT classification was cT1 in 62 cases, cT2 in 51, and cT3 in 4. We compared patients by patient background; prognosis, including postoperative complications; Results: Median operation time was 40 minutes （12-240） for TOS and 118 minutes （58-250） for PP-PC. Postoperative complications occurred in 10 cases （10/87, 11.5％） with TOS and 10 （10/30, 33.3％） with PP-PC （P ＝ 0.0275）. postoperative hospital stay was 7 days （4-137） with TOS and 15 days （9-37） with PP-PC （P ＝ 0.002）. function Five-year overall survival rate for 0.99）. hypopharyngeal cancer （cT1N0, cT2N0 and some cT3N0 without muscular infiltration）.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiotherapy for adenoid cystic carcinoma of the head and neck 头颈部腺样囊性癌的放射治疗

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.279

N. Mizoguchi, K. Shirai, Kio Kano, Wataru Anno, K. Tsuchida, Y. Takakusagi, Itsuko Serizawa, K. Akahane, Masahiro Kawahara, T. Kamada, D. Yoshida, H. Katoh

引用次数: 1

Potential retropharyngeal lymph node metastasis on diagnostic image and changes in retropharyngeal regional dose depending on the irradiation technique in maxillary sinus cancer 上颌窦癌咽后淋巴结潜在转移的诊断影像及不同照射技术下咽后区域剂量的变化

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/JJHNC.47.47

Y. Kosugi, T. Kawamoto, M. Oshima, Michimasa Suzuki, M. Fujimaki, S. Ohba, F. Matsumoto, N. Shikama, K. Sasai

{"title":"Potential retropharyngeal lymph node metastasis on diagnostic image and changes in retropharyngeal regional dose depending on the irradiation technique in maxillary sinus cancer","authors":"Y. Kosugi, T. Kawamoto, M. Oshima, Michimasa Suzuki, M. Fujimaki, S. Ohba, F. Matsumoto, N. Shikama, K. Sasai","doi":"10.5981/JJHNC.47.47","DOIUrl":"https://doi.org/10.5981/JJHNC.47.47","url":null,"abstract":"We retrospectively analyzed the frequency of retropharyngeal lymph node （Rp） metastasis on diagnostic images and the irradiation dose to the same area in 55 patients with advanced maxillary sinus squamous cell carcinoma who underwent external radiotherapy and superselective intra-arterial chemotherapy at Juntendo Hospital. Reassessment of pretreatment images revealed potential Rp metastases in 10 patients （18％）; 9 who were diagnosed with a minor axis of ≥ 5 mm and 1 diagnosed with a major axis of ≥ 10 mm. Patients who underwent MRI or PET-CT tended to have a high rate of Rp node metastases （P ＝ 0.090）. The median irradiation dose for Rp metastasis was 57.7 Gy, and 8/10 patients were irradiated with high doses without targeting. As a result, no recurrence of Rp metastasis was observed. When the Rp region is not targeted during intensity-modulated radiation therapy, the Rp region dose is significantly lower than that of three-dimensional radiation therapy （47.4 Gy vs. 36.0 Gy, respectively; p ＝ 0.040）.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A case of scarring stenosis of the transferred free jejunum due to temporary obstruction of the vascular anastomosis site 游离空肠移植因血管吻合处暂时性阻塞致瘢痕性狭窄1例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.348

Ryotaro Nakazawa, K. Akashi, S. Kishimoto

{"title":"A case of scarring stenosis of the transferred free jejunum due to temporary obstruction of the vascular anastomosis site","authors":"Ryotaro Nakazawa, K. Akashi, S. Kishimoto","doi":"10.5981/jjhnc.47.348","DOIUrl":"https://doi.org/10.5981/jjhnc.47.348","url":null,"abstract":"of the transferred free jejunum due to temporary obstruction of the vascular anastomosis site: Total pharyngolaryngoesophagectomy （TPLE） is performed on patients with advanced head and neck cancer. It is most frequently followed by pharyngoesophageal reconstruction with free jejunal flap because there is a relatively low operative risk and it improves postoperative function of the reconstructed pharynx and esophagus. A 79-year-old man developed hypopharyngeal carcinoma and underwent TPLE, neck dissection on both sides, and free jejunal transfer at our hospital. Early after surgery, we conducted thrombectomy because obstruction by the artery anastomotic region occurred. Blood flow was improved by early thrombectomy, and the flap sur-vived. However, a scarring stenosis which gradually reached full length occurred, and so we performed free jejunal transfer again. The pathological findings indicated that the mucosa had atrophied and been lost, while blood vessels were preserved. Even if the free jejunal flap survives early reoperation for vascular problems after TPLE, it may gradually develop scarring and stenosis.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of radiation-induced malignant tumor in the head and neck area 头颈部放射性恶性肿瘤1例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/JJHNC.47.83

Naoki Akisada, N. Monden, Jiro Aoi, Y. Hayashi, Saori Takahashi, Masataka Nakamura

引用次数: 0

Diffuse sclerosing variant of papillary thyroid carcinoma 甲状腺乳头状癌的弥漫性硬化变型

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.382

T. Hirata, Tomohito Fuke, Mamika Kaneko, Daisuke Kobayashi, Hiroyuki Yamada

引用次数: 0

Superficial cervical lymph node metastasis as the initial manifestation of occult papillary thyroid carcinoma: A case report 隐匿性甲状腺乳头状癌以颈部浅表淋巴结转移为首发表现1例

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.337

Alisa Kimura, Shigefumi Morioka, K. Toyoda

{"title":"Superficial cervical lymph node metastasis as the initial manifestation of occult papillary thyroid carcinoma: A case report","authors":"Alisa Kimura, Shigefumi Morioka, K. Toyoda","doi":"10.5981/jjhnc.47.337","DOIUrl":"https://doi.org/10.5981/jjhnc.47.337","url":null,"abstract":"要旨甲状腺オカルト癌の多くはリンパ節転移により同定されるが,浅頸リンパ節への転移を契機に診断されることは稀である。今回,浅頸リンパ節への単独転移により診断に至った甲状腺オカルト癌の 1 例を経験した。症例は 51 歳男性,胸骨上縁の境界明瞭な腫瘤に対して摘出術を施行し,前頸筋群より浅層に存在する浅頸リンパ節への甲状腺乳頭癌の転移と診断した。甲状腺には原発巣を確認できず,他に中央区域,外側区域リンパ節転移を認めなかったことから,浅頸リンパ節への単独転移を伴う甲状腺オカルト癌と診断した。本人希望で経過観察中,術後 14 ヶ月経過時に中央区域リンパ節転移を認め,甲状腺全摘術,両側 D1 郭清を施行し,甲状腺両葉に多発する微小腺内転移ならびに喉頭前,気管前,気管傍リンパ節転移を認めた。本例は特異な進展形式と比較的速い進行を示したオカルト癌症例であり,今後の診断の一助となると考え文献的考察を加えて報告する。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report of oropharyngeal clear cell carcinoma with revised pathological diagnosis after multi-gene cancer panel testing 口咽透明细胞癌1例经多基因肿瘤小组检查后病理诊断修改

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.342

Keiichi Koshizuka, K. Yamasaki, T. Kinoshita, T. Iinuma, S. Yonekura, T. Hanazawa

{"title":"A case report of oropharyngeal clear cell carcinoma with revised pathological diagnosis after multi-gene cancer panel testing","authors":"Keiichi Koshizuka, K. Yamasaki, T. Kinoshita, T. Iinuma, S. Yonekura, T. Hanazawa","doi":"10.5981/jjhnc.47.342","DOIUrl":"https://doi.org/10.5981/jjhnc.47.342","url":null,"abstract":"要旨標準治療が終了となった肺転移を伴う中咽頭癌患者に対して,がん遺伝子パネル検査を行った結果,扁平上皮癌から明細胞癌に病理学的診断が修正された患者を経験したので報告する。症例は 57 歳,女性,中咽頭扁平上皮癌,HPV 陰性,cT3N2bMX。シスプラチン併用放射線治療を施行したが,肺転移を疑っていた病変が増大した。ニボルマブ投与を行ったが,肺転移は更に増大し,セツキシマブ+パクリタキセル投与を開始した。その後,標準治療終了後の固形がんとしてがん遺伝子パネル検査を行った。治療対象となる遺伝子異常は認められなかったが,EWSR1-ATF1 融合遺伝子が検出された。この遺伝子は唾液腺明細胞癌の 80 ~ 90%の症例に検出される。この結果から,病理診断が扁平上皮癌から明細胞癌に修正された。後方視的に組織を確認しても,明細胞癌の診断は困難であり,がん遺伝子パネル検査が診断修正の契機となった症例であった。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strategy of neck dissection for early tongue cancer based on tumor invasion potential 基于肿瘤侵袭潜力的早期舌癌颈部清扫策略

Japanese Journal of Head and Neck Cancer Pub Date : 2021-01-01 DOI: 10.5981/jjhnc.47.295

Tomoya Ishida, Akimichi Minesaki, Eriko Shimazaki, M. Yamauchi, Rintaro Shimazu, Y. Kuratomi

{"title":"Strategy of neck dissection for early tongue cancer based on tumor invasion potential","authors":"Tomoya Ishida, Akimichi Minesaki, Eriko Shimazaki, M. Yamauchi, Rintaro Shimazu, Y. Kuratomi","doi":"10.5981/jjhnc.47.295","DOIUrl":"https://doi.org/10.5981/jjhnc.47.295","url":null,"abstract":"tumor invasion potential: pT re-classiﬁcation according to the UICC, 8th edition and evaluation of tumor invasion potential by the Yama-moto-Kohama （YK） classiﬁcation were performed for 45 patients with pT1, 2N0 oral tongue cancers （UICC, 7th edition） who had undergone surgical resection as initial treatment followed by observation. Association between the two factors and late cervical metastases and survival rates were analyzed. The number of patients with pT1/2/3 （UICC, 8th edition） and YK-1, 2/3/4C, 4D was 17/20/8 and 10/18/17, respectively. The late cervical metastasis rate and 5-year disease-speciﬁc survival rate for pT1/2/3 were 29/45/63％ and 88/85/63％, and for YK-1, 2/3/4C, 4D were 10/39/65％ and 100/100/53％, respectively. Tumor invasion potential was more strongly associated with prognosis than pT classiﬁcation （8th edition）. All of the low to moderately invasive YK-1-3 tumors were controlled by neck dissection after the appearance of late cervical metastasis, and therefore, the observation strategy seems to be appropriate for these tumors. In contrast, the highly invasive YK-4C, 4D tumors presented poor control rates by the observation strategy, and therefore, might need more intensive treatments such as additional neck dissection following primary tumor resection before late cervical metastasis appears.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0