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A Giant Lipoma in the Distal Forearm of a Cadaver. 尸体前臂远端的巨大脂肪瘤。
Acta medica academica Pub Date : 2023-08-01 DOI: 10.5644/ama2006-124.414
Konstantinos Natsis, Vlasios Achlatis, Maria Piagkou, Trifon Totlis
{"title":"A Giant Lipoma in the Distal Forearm of a Cadaver.","authors":"Konstantinos Natsis, Vlasios Achlatis, Maria Piagkou, Trifon Totlis","doi":"10.5644/ama2006-124.414","DOIUrl":"10.5644/ama2006-124.414","url":null,"abstract":"Objective. Lipomas are very common tumors which usually prefer the upper limbs and, depending on their size, may cause nerve compression, or may be asymptomatic. The current cadaveric report describes a giant lipoma in the distal forearm area. Case Report. A large mass (5.1 × 3.2 × 1.6 cm) was identified on the palmar surface of the distal forearm, during dissection of a 63-year-old male cadaver. The mass caused anteromedial displacement and flattening of the median nerve (MN). Despite the lack of information about the subject’s medical history, MN compression was assumed on the basis of the lipoma’s size, its vicinity to neural structures, and the MN displacement and flattening. Conclusion. The enlarged distal forearm lipoma, located adjacent to the carpal tunnel, displaced and flattened the MN. The cadaveric finding described is clinically relevant for both differential diagnosis and surgical treatment of carpal tunnel syndrome.","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 2","pages":"142-145"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10698365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical Variations in the Celiac Trunk: A Short Review. 腹腔主干的解剖学变异:一个简短的回顾。
Acta medica academica Pub Date : 2023-08-01 DOI: 10.5644/ama2006-124.413
Ioannis Vougadiotis, Vasileios Karampelias, Dimosthenis Chrysikos, Ioannis Antonopoulos, Eirini Solia, Ypatios Spanidis, George Tsakotos, Theodore Troupis
{"title":"Anatomical Variations in the Celiac Trunk: A Short Review.","authors":"Ioannis Vougadiotis, Vasileios Karampelias, Dimosthenis Chrysikos, Ioannis Antonopoulos, Eirini Solia, Ypatios Spanidis, George Tsakotos, Theodore Troupis","doi":"10.5644/ama2006-124.413","DOIUrl":"10.5644/ama2006-124.413","url":null,"abstract":"<p><strong>Objective: </strong>The objective of the current study was the examination of possible variants of the celiac trunk.</p><p><strong>Methods: </strong>An advanced review of the literature search was undertaken by means of the PubMed database and Google Scholar, searching for new studies published up to October 2022. Additional articles provided useful information in relation to the aim of this review. Hence, articles that met the inclusion criteria were included in this review and the collected data were organized into a table.</p><p><strong>Results: </strong>The search of the literature retrieved 10 articles that referred to the anatomical variations of the celiac trunk. According to the available literature, the most common anatomical variations are: hepatosplenic trunk where the left gastric artery originates from the abdominal aorta, hepatosplenic trunk, where the left gastric artery originates from the splenic artery, and hepatogastric trunk and splenic artery origin from the superior mesenteric artery. Many other anatomical variations of the celiac trunk may exist, such as tetrafurcation, pentafurcation and hexafurcation, that refer to the division of the celiac trunk into four, five or six branches, respectively, and should be reported as they can affect surgical approaches and the development of the appropriate treatment strategy in patients.</p><p><strong>Conclusion: </strong>Every visceral surgeon, interventional radiologist and abdominal imager should be familiar with these variants.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 2","pages":"134-141"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10698368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pneumomediastinum: Experience with 87 Patients. 纵隔肺炎87例诊治体会。
Acta medica academica Pub Date : 2023-08-01 DOI: 10.5644/ama2006-124.408
Dimitrios E Magouliotis, Ioanna Sgantzou, Nikolaos S Salemis, Christos Rountas, Athina Samara, Prokopis-Andreas Zotos, Thanos Athanasiou, Kyriakos Spiliopoulos
{"title":"Pneumomediastinum: Experience with 87 Patients.","authors":"Dimitrios E Magouliotis, Ioanna Sgantzou, Nikolaos S Salemis, Christos Rountas, Athina Samara, Prokopis-Andreas Zotos, Thanos Athanasiou, Kyriakos Spiliopoulos","doi":"10.5644/ama2006-124.408","DOIUrl":"10.5644/ama2006-124.408","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present series was first to present our experience in the management of 37 patients with spontaneous pneumomediastinum (SPM), and further to indicate the necessity of identifying true SPM cases as they are currently inadequately defined.</p><p><strong>Methods: </strong>This is a single-center, retrospective study, conducted in a university hospital. Consecutive adult patients with pneumomediastinum (PM) between January 2009 and March 2020 were involved in the series. The data about age, gender, symptoms, signs, treatment, length of hospital stay (LOS), and in-hospital mortality were evaluated.</p><p><strong>Results: </strong>In total, 87 cases with pneumomediastinum (37 with spontaneous and 50 with secondary PM) were analyzed. Patients in both groups were of similar ages (P=0.4). Sufferers with secondary PM were more likely to have: an associated pneumothorax (19% vs 58%, P<0.05), a chest tube placed (18.9% vs 58%, P<0.05), an associated pleural effusion (0% vs 18%, P<0.05). They presented with a longer LOS (3.9 vs 5.3 days, P<0.05), and were more likely to die (0% vs 10%, P<0.05). Additionally they showed a higher prevalence of radiologic subcutaneous emphysema (49% vs 74%, P<0.05).</p><p><strong>Conclusion: </strong>Spontaneous pneumomediastinum is an onset of clinical importance with a low mortality rate, short LOS and good longterm prognosis. It often presents with chest pain, dyspnea and/or subcutaneous emphysema. However, secondary causes of mediastinal air must be ruled out, due to their potential devastating outcome if not diagnosed promptly. A consensus aimed at an update of the classification guidelines is more than indispensable.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 2","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10698360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Seroprevalence in Children during Pandemic Waves in Sarajevo, a Single Center Experience. 萨拉热窝大流行期间儿童COVID-19血清阳性率:单一中心体验
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.403
Senka Mesihović-Dinarević, Mirela Lisičić-Konaković, Jasminka Prguda-Mujić, Anes Jogunčić
{"title":"COVID-19 Seroprevalence in Children during Pandemic Waves in Sarajevo, a Single Center Experience.","authors":"Senka Mesihović-Dinarević,&nbsp;Mirela Lisičić-Konaković,&nbsp;Jasminka Prguda-Mujić,&nbsp;Anes Jogunčić","doi":"10.5644/ama2006-124.403","DOIUrl":"https://doi.org/10.5644/ama2006-124.403","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to present data on the prevalence of seropositive children tested in the laboratory of the Eurofarm polyclinic in Sarajevo, from September 2020 to May 2021.</p><p><strong>Materials and methods: </strong>Peripheral blood samples were collected and anti-SARS-CoV-2 antibodies were detected using an electrochemiluminescence immunoassay.</p><p><strong>Results: </strong>In the total of 762 tested children, 187 were positive (24.5%), based on cut-off value. Of all the positive cases 42.8% were female while 57.2% were male. There were 10.1% of positive children in the first age group (0-5 years), 44.4% in the second group (6-13 years), and 45.5% in the third group (14-18 years). There was no statistically significant difference in seroprevalence between age groups and gender. The lowest seroprevalence (3.6%) was observed in October 2020 after the first pandemic wave, and the highest seroprevalence (60.3%) was observed in April 2021, corresponding to the third pandemic wave.</p><p><strong>Conclusion: </strong>The results of our study showed that the seroprevalence in children was low, especially during the first year of the pandemic. In the second year of the pandemic, there was an evident statistically significant increase in the number of seropositive children. Similar data have been shown in studies for adults.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"56-62"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/e0/AMA-52-56.PMC10316078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9740837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family Physicians' Perceptions of Primary Health Care Use in Bosnia and Herzegovina during the Covid-19 Pandemic, a Cross-sectional Study. 在2019冠状病毒病大流行期间,波斯尼亚和黑塞哥维那家庭医生对初级卫生保健使用的看法:一项横断面研究
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.397
Zaim Jatić, Eman Smlatic, Madelynne McGowan, Hasiba Erkočević, Elvira Hasanović, Nataša Trifunović
{"title":"Family Physicians' Perceptions of Primary Health Care Use in Bosnia and Herzegovina during the Covid-19 Pandemic, a Cross-sectional Study.","authors":"Zaim Jatić,&nbsp;Eman Smlatic,&nbsp;Madelynne McGowan,&nbsp;Hasiba Erkočević,&nbsp;Elvira Hasanović,&nbsp;Nataša Trifunović","doi":"10.5644/ama2006-124.397","DOIUrl":"https://doi.org/10.5644/ama2006-124.397","url":null,"abstract":"<p><strong>Objectives: </strong>The main objective of this paper was to examine the perceptions of family physicians on the use of primary health care in Bosnia and Herzegovina during the COVID-19 pandemic.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted using a short online questionnaire that was sent to primary care physicians in Bosnia and Herzegovina from April 20th, 2022, to May 20th, 2022.</p><p><strong>Results: </strong>The research sample consisted of 231 doctors of primary health care from Bosnia and Herzegovina, with an average age of 45 years and 85% women. About 70% of participants reported having COVID-19 at least once from March 2020 to March 2022. Participants had an average of 1,986 registered patients and approximately 50 encounters per day. The study revealed a high degree of reliability between test-retest measurements, with a single measure Intraclass correlation coefficient of 0.801, and internal consistency determined using Cronbach's alpha of 0.89. Participants reported that the following health services were most affected during the COVID-19 pandemic: care for patients with chronic diseases, home visits, navigating the health system with patients making appointments with specialists, cancer screening, and preventive health services. The study also found statistically significant perceived differences in the use of these health services based on age, gender, postgraduate education in family medicine, participation in COVID-19 clinics, and personal history of Covid-19.</p><p><strong>Conclusion: </strong>There were significant disturbances to the use of primary health care during the COVID-19 pandemic. Future research could investigate patient outcomes compared to family physician perceptions.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"13-23"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/f9/AMA-52-13.PMC10316076.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9740839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Predictive of In-Hospital Mortality in Patients with Systemic Lupus Erythematosus: A Single-Centre Retrospective Analysis. 预测系统性红斑狼疮患者住院死亡率的因素:单中心回顾性分析
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.400
Sujin Lertwises, Attapon Rattanasupar, Arunchai Chang
{"title":"Factors Predictive of In-Hospital Mortality in Patients with Systemic Lupus Erythematosus: A Single-Centre Retrospective Analysis.","authors":"Sujin Lertwises,&nbsp;Attapon Rattanasupar,&nbsp;Arunchai Chang","doi":"10.5644/ama2006-124.400","DOIUrl":"https://doi.org/10.5644/ama2006-124.400","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to investigate the causes and factors predictive of in-hospital death among patients with systemic lupus erythematosus (SLE) admitted to a tertiary care hospital in Thailand.</p><p><strong>Materials and methods: </strong>We retrospectively reviewed the records of patients with SLE admitted between 2017 and 2021. We collected data related to age, sex, body mass index, comorbidities, disease duration, medication usage, clinical symptoms, vital signs, laboratory results, evidence of infection, presence of systemic inflammatory response syndrome, quick sepsis-related organ assessment scores, and SLE disease activity on the date of admission. The length of hospitalization, treatment administered, and subsequent clinical outcomes (including in-hospital complications and death) were also recorded.</p><p><strong>Results: </strong>Among 267 enrolled patients, the overall in-hospital mortality rate was 25.5%, and infection was the most common cause of death (75.0%). Multivariate analysis revealed that prior hospitalization within 3 months (odds ratio [OR]: 2.311; 95% confidence interval [CI]: 1.002-5.369; P=0.049), initial infection on admission (OR: 2.764; 95% CI: 1.006-7.594; P=0.048), use of vasopressor drugs (OR: 2.940; 95% CI: 1.071-8.069; P=0.036), and mechanical ventilation (OR: 5.658; 95% CI: 2.046-15.647; P=0.001) were independent risk factors for in-hospital mortality.</p><p><strong>Conclusion: </strong>Infection was the major cause of mortality in patients with SLE. Prior hospitalization within 3 months, initial infection on admission, vasopressor use, and mechanical ventilation during admission are independent risk factors for in-hospital mortality in patients with SLE.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"37-46"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/19/AMA-52-37.PMC10316072.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Coexistence of an Incomplete Superficial Palmar Arch and a Berrettini Anastomosis: A Case Report. 掌浅弓不全与Berrettini吻合并存1例。
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.401
Ioannis Antonopoulos, Panagiotis Giavopoulos, Dimosthenis Chrysikos, Dimitrios Filippou, Theodore Troupis
{"title":"The Coexistence of an Incomplete Superficial Palmar Arch and a Berrettini Anastomosis: A Case Report.","authors":"Ioannis Antonopoulos,&nbsp;Panagiotis Giavopoulos,&nbsp;Dimosthenis Chrysikos,&nbsp;Dimitrios Filippou,&nbsp;Theodore Troupis","doi":"10.5644/ama2006-124.401","DOIUrl":"https://doi.org/10.5644/ama2006-124.401","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to present a relatively rare case of the coexistence of an incomplete superficial palmar arch and a Berrettini anastomosis, identified in a cadaveric specimen, and further discuss the potential clinical implications of such anatomical variations.</p><p><strong>Case report: </strong>The variation was found in the left hand of a formalin-fixed male cadaver of Greek origin, that was dissected under an operating microscope (×4, ×10 magnification) in our Anatomy Department. In the specimen, we found an incomplete superficial palmar arch, formed only by the superficial branch of the ulnar artery, and a Type 1 Berrettini Anastomosis, originating from the ulnar nerve and joining a branch of the median nerve.</p><p><strong>Conclusion: </strong>To avoid iatrogenic damage and permanent loss of sensation, hand surgeons and microsurgeons should be aware of the presence of a BA, and the potential coexistence of this variation with vascular abnormalities in the hand that may complicate surgical procedures.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/46/AMA-52-47.PMC10316074.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9740836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When to Attend a Webinar? 什么时候参加网络研讨会?
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.404
Farrokh Habibzadeh
{"title":"When to Attend a Webinar?","authors":"Farrokh Habibzadeh","doi":"10.5644/ama2006-124.404","DOIUrl":"https://doi.org/10.5644/ama2006-124.404","url":null,"abstract":"<p><strong>Objective: </strong>To determine the most appropriate delay to start a webinar.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on weekly general staff scientific webinars held by the Institute of Human Virology (IHV), University of Maryland School of Medicine, Baltimore, USA. 35 observations were made at arbitrary chosen times of three consecutive IHV webinars. After standardizing the number of participants, a 4th-degree polynomial fit was applied to the data. A cost function was defined as the sum of the time wasted for those who attended the webinar early and the lost for those who attend with delay. The cost function was minimized to compute the most appropriate delay to start the webinar.</p><p><strong>Results: </strong>The model could explain almost 95% of the observed variance in the number of participants. Normally, half of the participants attended the meeting at the webinar set starting time. The cost was a minimum if the webinar was delayed for about 3 minutes.</p><p><strong>Conclusion: </strong>It seems that the most appropriate time for starting the IHV general staff meetings is around 3 minutes after the webinar set starting time.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"63-66"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/89/7d/AMA-52-63.PMC10316075.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Brachiocephalic Trunk Variant Origin and High-Riding Course: Two Cadaveric Cases. 头臂躯干变异起源与高程:两例尸体。
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.402
George Tsakotos, Theano Demesticha, Vasilios Karampelias, Konstantinos Natsis, Vasilios Protogerou, Dimitrios Schizas, Ilenia Chatziandreou, Georgia Kostare, Maria Piagkou
{"title":"The Brachiocephalic Trunk Variant Origin and High-Riding Course: Two Cadaveric Cases.","authors":"George Tsakotos,&nbsp;Theano Demesticha,&nbsp;Vasilios Karampelias,&nbsp;Konstantinos Natsis,&nbsp;Vasilios Protogerou,&nbsp;Dimitrios Schizas,&nbsp;Ilenia Chatziandreou,&nbsp;Georgia Kostare,&nbsp;Maria Piagkou","doi":"10.5644/ama2006-124.402","DOIUrl":"https://doi.org/10.5644/ama2006-124.402","url":null,"abstract":"<p><strong>Objective: </strong>The current report describes two rare cadaveric findings of a left sided brachiocephalic trunk (BCT) in relation to the trachea, and its high-riding course above the suprasternal notch (SN).</p><p><strong>Cases description: </strong>In two elderly body donors dissected after death, a left-sided BCT was identified with a high-riding course (0.5 and 0.8 cm above the SN). The BCT originated from the aortic arch, in common with the left common carotid artery, more distally than the typical left-side location and crossed in front of the trachea. In the 1st case, the ascending and descending aortae, and the left subclavian artery had aneurysmal dilatation. In both cases, the trachea was displaced to the right side and had a stenosis due to the chronic compression.</p><p><strong>Conclusion: </strong>A high-riding BCT is of paramount clinical importance, as it may complicate tracheotomy, thyroid surgery and mediastinoscopy, leading to fatal complications. BCT injury leads to a massive bleeding during neck dissection (level VI), when the vessel crosses the anterior tracheal wall.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"51-55"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/03/8c/AMA-52-51.PMC10316069.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SARS-CoV-2 Vaccination IgG Antibody Responses in Patients with Hematologic Malignancies in a Myeloid Enriched Cohort: A Single Center Observation. 骨髓富集队列血液恶性肿瘤患者的SARS-CoV-2疫苗IgG抗体反应:单中心观察
Acta medica academica Pub Date : 2023-04-01 DOI: 10.5644/ama2006-124.399
Fieke W Hoff, Suleyman Y Goksu, Naveen Premnath, Prapti A Patel, Ruth Ikpefan, Gurbakhash Kaur, Madhuri Vusirikala, Taha Bat, Weina Chen, Praveen Ramakrishnan Geethakumari, Larry D Anderson, Farrukh T Awan, Robert H Collins, Olga K Weinberg, Alagarraju Muthukumar, Stephen S Chung, Yazan F Madanat
{"title":"SARS-CoV-2 Vaccination IgG Antibody Responses in Patients with Hematologic Malignancies in a Myeloid Enriched Cohort: A Single Center Observation.","authors":"Fieke W Hoff,&nbsp;Suleyman Y Goksu,&nbsp;Naveen Premnath,&nbsp;Prapti A Patel,&nbsp;Ruth Ikpefan,&nbsp;Gurbakhash Kaur,&nbsp;Madhuri Vusirikala,&nbsp;Taha Bat,&nbsp;Weina Chen,&nbsp;Praveen Ramakrishnan Geethakumari,&nbsp;Larry D Anderson,&nbsp;Farrukh T Awan,&nbsp;Robert H Collins,&nbsp;Olga K Weinberg,&nbsp;Alagarraju Muthukumar,&nbsp;Stephen S Chung,&nbsp;Yazan F Madanat","doi":"10.5644/ama2006-124.399","DOIUrl":"https://doi.org/10.5644/ama2006-124.399","url":null,"abstract":"<p><strong>Objective: </strong>Patients diagnosed with hematologic malignancies are at increased risk for severe SARS-CoV-2 infection. We evaluated the serological IgG response following two doses of the SARS-CoV-2 vaccine in patients with hematologic malignancies.</p><p><strong>Methods: </strong>Patients treated at UT Southwestern Medical Center with a diagnosis of a myeloid or lymphoid neoplasm were included. SARS-CoV-2 vaccination response was defined as a positive quantifiable spike IgG antibody titer.</p><p><strong>Results: </strong>Sixty patients were included in the study and 60% were diagnosed with a myeloid neoplasm. The majority (85%) of the patients with a myeloid malignancy and 50% of the patients with a lymphoid malignancy mounted a serological response after receiving two doses of the vaccine.</p><p><strong>Conclusion: </strong>Vaccination should be offered irrespective of ongoing treatment or active disease. Findings require validation in a larger cohort of patients.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"52 1","pages":"30-36"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/2b/AMA-52-30.PMC10316070.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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