Acta medica academica最新文献

{"title":"Researching the Phenomenon of Poor Ovarian Responders and Management Strategies in IVF: A Narrative Review.","authors":"Dionysios Galatis,&nbsp;Konstantina Kalopita,&nbsp;Ioannis Grypiotis,&nbsp;Ioannis Flessas,&nbsp;Nikolaos Kiriakopoulos,&nbsp;Georgia Micha","doi":"10.5644/ama2006-124.379","DOIUrl":"https://doi.org/10.5644/ama2006-124.379","url":null,"abstract":"<p><p>This narrative review aims to summarize all the latest studies published between 2015-2021 concerning the management protocols adopted for poor ovarian response (POR) cases. Patients defined as \"poor responders\" show minimal response to controlled ovarian hyperstimulation, although there is no standard definition for POR. Although infertility specialists are endeavoring to improve cycle outcomes in poor responders by adopting multiple management strategies, still the estimated risk of cycle cancellation is about 20%. All the studies performed during this study period were evaluated and their results were recorded. The latest published protocols to improve oocyte retrieval in poor responders include: anti-Mϋllerian hormone, clomiphene citrate, co-enzyme Q10, corifollitropin, dehydroepiandrosterone, double stimulation, Follicle Stimulation Hormone, Growth Hormone, Gonadotropin-releasing hormone agonists, letrozole, human chorionic gonadotropin, Luteinizing Hormone, progesterone and testosterone. CONCLUSION: Although many strategies have been suggested to manage POR, none has been proven superior to the others. Further large-scale randomized studies are needed to validate experimental techniques leading towards successful individualized treatment regimens.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"108-122"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/e3/AMA-51-108.PMC9982854.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9102513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Analysis of the Supraorbital Foramen and Notch in the Population of Bosnia and Herzegovina.","authors":"Alma Voljevica,&nbsp;Elvira Talović,&nbsp;Maida Šahinović,&nbsp;Amna Pleho-Kapić","doi":"10.5644/ama2006-124.377","DOIUrl":"https://doi.org/10.5644/ama2006-124.377","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to learn about the morphological characteristics of the supraorbital foramen and to determine its precise position in relation to the surrounding anatomical landmarks in the adult population of Bosnia and Herzegovina.</p><p><strong>Material and methods: </strong>For this purpose, 60 skulls from the Bosnia and Herzegovina population of known sex (32 males and 28 females), taken from the osteological collection of the Department of Human Anatomy of the Medical Faculty in Sarajevo, were subjected to morphological and morphometric analysis. Morphometric measurements were performed using a digital vernier caliper (Mitutoyo Corporation, Japan).</p><p><strong>Results: </strong>The study showed that most supraorbital nerves exit the orbit through the supraorbital notch (73.8%) and the rest through the foramen (26.2%). Of this number, bilateral supraorbital notches were recorded in 58.33% of cases, a bilateral supraorbital foramen in 18.34% of cases, while in 23.33% of cases a notch was recorded on one side and a foramen on the contralateral side. Morphometric measurements performed to determine the exact position of the supraorbital foramen relative to the surrounding landmarks showed different values in males and females. An accessory foramen was also observed on the examined skulls in 16.67% of cases.</p><p><strong>Conclusion: </strong>Detailed knowledge of anatomical variations of the supraorbital foramen is required for safe and successful administration of regional anesthesia, in order to avoid iatrogenic nerve injuries during orbitofacial region surgery.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"92-98"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/a6/AMA-51-92.PMC9982859.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9106999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Text Neck Syndrome: Disentangling a New Epidemic.","authors":"Alexandra-Regina Tsantili,&nbsp;Dimosthenis Chrysikos,&nbsp;Theodore Troupis","doi":"10.5644/ama2006-124.380","DOIUrl":"https://doi.org/10.5644/ama2006-124.380","url":null,"abstract":"<p><p>The aim of this report is to provide a brief review of the predisposing factors for Text Neck Syndrome, along with diagnostic and therapeutic approaches in young and adult populations. Text neck pain is a worldwide public health problem, largely reported nowadays. Currently, data have shown that the erroneous use of personal computers and cell phones might be correlated with the development of various clinical symptoms that are defined as \"text neck syndrome\". Modified radical changes in everyday life may ameliorate the powerful forces on the cervical spine that can lead to cervical degeneration, along with other developmental, medical, psychological, and social complications that are attributed to text neck syndrome. CONCLUSION: New technologies and the potentially harmful addiction to cell phones and computers while reading or texting are inducing an epidemic of text neck syndrome. By focusing on postural correction, both pain alleviation and a better quality of life can be achieved for the patient. The predisposing factors and therapeutic approaches for this syndrome that affects public health remain to be further elucidated.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"123-127"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/17/fd/AMA-51-123.PMC9982850.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9102514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On Measuring Vaccine Effectiveness with Observational Study Designs.","authors":"Farrokh Habibzadeh,&nbsp;Parham Habibzadeh,&nbsp;Mahboobeh Yadollahie","doi":"10.5644/ama2006-124.383","DOIUrl":"https://doi.org/10.5644/ama2006-124.383","url":null,"abstract":"Herein, we present a bird’s eye view of common observational study designs utilized for measurement of vaccine effectiveness. Assessing vaccines effectiveness is an integral part of vaccine research, particularly for the newly developed vaccines. A cohort study is prospective, directing from an exposure to one or more outcomes. The design is the best method to ascertain the attack rate of an infectious disease. A traditional case-control study is retrospective, directing from a given outcome to one or more exposures. The design cannot provide the relative risk, but it can provide the odds ratio, which is a good estimation of the relative risk when the attack rate is low. Critically depending on laboratory test results and performance, the test-negative case-control study design is another type of observational study commonly used nowadays for the evaluation of the vaccine effectiveness. Comparing to cohort and traditional case-control designs, conducting a test-negative case-control study is relatively cheaper and faster. Herein, we describe each of the above-mentioned study designs through examples generated by a Monte-Carlo simulation program assuming real-world conditions. Conclusion. The simulation shows that regardless of the study design employed, the diagnostic test specificity is of utmost importance in providing a valid estimate of the vaccine effectiveness.","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"134-146"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/be/85/AMA-51-134.PMC9982864.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9102512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Giant Polypoid Gastric Heterotopia of the Ileum as a Cause of Intussusception in an Adolescent.","authors":"Jasmina Redzepagic,&nbsp;Kenan Karavdic,&nbsp;Alena Firdus,&nbsp;Haris Kuric,&nbsp;Deniz Bulja,&nbsp;Nermina Ibisevic,&nbsp;Zlatan Zvizdic,&nbsp;Semir Vranic","doi":"10.5644/ama2006-124.382","DOIUrl":"https://doi.org/10.5644/ama2006-124.382","url":null,"abstract":"No abstract available.","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"132-133"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/f8/AMA-51-132.PMC9982848.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9102515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudohyponatremia Secondary to Hypercholesterolemia in the Setting of Intrahepatic Cholestasis due to Metastatic Liver Disease: A Case Report and Review of the Literature.","authors":"Leili Pourafkari,&nbsp;Christian Cavalieri,&nbsp;Seyedeh Kimia Yavari,&nbsp;Nader D Nader","doi":"10.5644/ama2006-124.381","DOIUrl":"https://doi.org/10.5644/ama2006-124.381","url":null,"abstract":"<p><strong>Objective: </strong>We describe a rare case of pseudohyponatremia in the setting of hypercholesterolemia caused by cholestasis due to metastatic liver disease and provide a review of the published cases in the literature.</p><p><strong>Case report: </strong>We report a case of pseudohyponatremia in a 60-year-old man with rectal cancer with extensive metastasis to the liver. While assessing the patient for hyponatremia, extremely elevated serum cholesterol with normal serum osmolality was detected leading to the diagnosis of pseudohyponatremia. This is one of very few reports of pseudohyponatremia in patients with elevated cholesterol in cholestatic liver disease.</p><p><strong>Conclusion: </strong>Hypercholesterolemia is an exceedingly rare cause for pseudohyponatremia. Although pseudohyponatremia per se does not carry a risk to the patient, the delay in diagnosis and treatment plans may pose additional risks. Pseudohyponatremia needs to be considered in patients with low sodium and co-existing cholestasis from metastatic liver disease.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"128-131"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d3/76/AMA-51-128.PMC9982855.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9102517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Biography of Isak Samokovlija: The Famous Bosnian-Herzegovinian Writer.","authors":"Husref Tahirović","doi":"10.5644/ama2006-124.384","DOIUrl":"https://doi.org/10.5644/ama2006-124.384","url":null,"abstract":"<p><p>The purpose of this paper is to shed light on the biographical, professional, and health-educational works of Dr. Isak Samakovlija, who was better known as a writer than a doctor in the country where he was born. He was born in 1889 in Goražde, the easternmost province in the Austrian-Hungarian monarchy, into a modest Jewish merchant family. He attended high school in Sarajevo and completed his studies in medicine in Vienna in 1917. During the First World War, he served twice in the Austro- Hungarian army. After the end of the First World War in 1918, he completed a medical internship at the National Hospital in Sarajevo. He began his service as a doctor, first in Goražde and then in Fojnica and Sarajevo. After the establishment of the Independent State of Croatia in May 1941, he was dismissed from his duties in the service without the right to pension or support, and without the right to appeal. In the Independent State of Croatia, he was twice mobilized into the Home Guard and was manager of the clinic in the Alipašin Most refugee camp. After World War II, he was the head of the Health Education Department of the Ministry of Public Health of the People's Republic of Bosnia and Herzegovina in Sarajevo. Together with a group of enthusiastic doctors, he founded and edited the first Bosnian medical journal Život i Zdravlje (Life and Health). In that journal, Dr. Samokovlija published 29 articles of health and educational content. In 1949, Dr. Samokovlija left the Ministry of Public Health and continued to edit the literature and art journal Brazda, but he still had a private practice until the end of his life. He died in Sarajevo on January 15, 1955. He was buried with the highest state honors at the Jewish cemetery in Sarajevo. CONCLUSION: Isak Samakovlija (1889-1955) was one of the first medical doctors born in Bosnia and Herzegovina. He made a significant contribution to the improvement of people's health after the First and Second World Wars in the places where he worked. His special contribution are his articles on health education.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"147-162"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/49/AMA-51-147.PMC10018996.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9130345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of SARS-CoV-2 Antibody Response Post Third Dose COVID-19 mRNA Vaccination at Universitas Indonesia Hospital.","authors":"Rakhmad Hidayat,&nbsp;Alyssa Putri Mustika,&nbsp;Fhathia Avisha,&nbsp;Zlatikha Djuliannisaa,&nbsp;Dinisa Diah Winari,&nbsp;Ria Amiliah Putri,&nbsp;Heydi Marizky Lisman,&nbsp;Vandra Davin,&nbsp;Gemia Clarisa Fathi,&nbsp;Alvina Widhani,&nbsp;Muhammad Hafiz Aini,&nbsp;Yudhistira Yudhistira,&nbsp;Siti Azizah,&nbsp;Meilisa Rahmadani,&nbsp;Novita Dwi Istanti,&nbsp;Astuti Giantini","doi":"10.5644/ama2006-124.374","DOIUrl":"https://doi.org/10.5644/ama2006-124.374","url":null,"abstract":"<p><strong>Objective: </strong>The longevity of vaccine effectiveness and antibody titer after the Moderna mRNA COVID-19 vaccination booster in healthcare workers in Indonesia is not known.</p><p><strong>Materials and methods: </strong>We performed a prospective observational study of healthcare workers at the Universitas Indonesia Hospital after Moderna mRNA COVID-19 booster vaccination. An Immunology Analyzer with Chemiluminescence Immunoassay (CLIA) test was used to examine Anti SARS-CoV-2 S-RBD levels. Antibody levels were classified into two systems (3 categories, and 2 categories).</p><p><strong>Results: </strong>There were 31 male subjects (75.6%), 33 subjects (80.5%) aged 25-39 years, 17 subjects (41.5%) with overweight BMI, 35 subjects (85.4%) without comorbidities, and 29 subjects without previous history of COVID-19 infection (70.7%) who had antibody titer >1000 AU/ml. There were 27 subjects (65.9%) who had a booster shot ≥6 months after the second vaccination with antibody titer >1000 AU/ml. In this study, there was no significant correlation between antibody titer with factors such as gender, age, BMI, comorbidities, history of COVID-19 infection and time between the 2nd vaccination and booster vaccination.</p><p><strong>Conclusion: </strong>There is no significant correlation between antibody titer with factors such as gender, age, BMI, comorbidities, history of COVID-19 infection and time between the 2nd vaccination and booster vaccination.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"69-78"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/9a/AMA-51-69.PMC9982858.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9102516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Effectiveness between Wycope Video Laryngoscope, C-MAC Video Laryngoscope, and Direct Laryngoscope in Intubation of Elective Surgery Patients.","authors":"Jayadi Jayadi,&nbsp;Anna Surgean Veterini,&nbsp;Edward Kusuma,&nbsp;Christrijogo Sumartono Waloejo,&nbsp;Prananda Surya Airlangga,&nbsp;Bambang Pujo Semedi","doi":"10.5644/ama2006-124.378","DOIUrl":"https://doi.org/10.5644/ama2006-124.378","url":null,"abstract":"<p><strong>Objective: </strong>Airway management has undergone a dramatic transformation since the arrival of video laryngoscope (VL). VL has higher intubation success rate on first try and lower complications in comparison to direct laryngoscope (DL). The use of VL is recommended in intubating COVID-19 patients to speed up intubation time and reduce failure rate. A team from Airlangga University developed Wycope Video Laryngoscope (Wycope VL), a VL with Wi-Fi connection to smartphones for an easier VL with low cost. This study aimed to compare the effectiveness of Wycope VL, C-MAC Video Laryngoscope (C-MAC VL), and DL.</p><p><strong>Materials and methods: </strong>This study was an analytic observational study with a cross sectional design, involving 63 patients who were divided into 3 groups based on the type of laryngoscope, namely Wycope VL, C-MAC VL, and DL. Intubation is carried out by 4th year anaesthesiology resident. Research subjects were patients who will undergo elective surgery at Dr. Soetomo General Hospital under general anaesthesia using orotracheal tube. Inclusion age of 19-64 years, PS ASA 1-2, no anatomical abnormalities of the airway, did not have difficult airway, and was willing to participate in the study.</p><p><strong>Results: </strong>All patients were successfully intubated without complications. C-MAC VL (5.33±1.42 seconds) and Wycope VL (5.95±0.74 seconds) was significantly faster in seeing vocal folds and glottis compared to DL (7.14±0.72 seconds) with P=0.000. DL was significantly faster in average time of intubation (15.52±5.90 seconds) compared to C-MAC VL (16.95±1.11 seconds) and Wycope VL (20.29±2.81 seconds) with P=0.000.</p><p><strong>Conclusion: </strong>DL was faster compared to VL in speed of intubation while C-MAC VL and Wycope VL was faster in viewing the vocal folds and glottis compared to DL.</p>","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 2","pages":"99-107"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/dc/AMA-51-99.PMC9982846.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9106998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large Bowel Obstruction Secondary to Urinary Retention.","authors":"Seyedeh Kimia Yavari,&nbsp;Leili Pourafkari","doi":"10.5644/ama2006-124.372","DOIUrl":"https://doi.org/10.5644/ama2006-124.372","url":null,"abstract":"No abstract available.","PeriodicalId":38313,"journal":{"name":"Acta medica academica","volume":"51 1","pages":"64-65"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1a/b0/AMA-51-64.PMC9982847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9101481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}