Bioactive Carbohydrates and Dietary Fibre最新文献

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Bio synthesis of chitosan from shrimp shell chitin using Streptomyces griseoincarnatus RB7AG:Characterization and application as coating material to enhance shelf life of tomatoes (var. Ruby pusa) in post-harvest storgae condition 利用链霉菌 Griseoincarnatus RB7AG 从虾壳甲壳素中生物合成壳聚糖:表征及作为涂层材料的应用,以提高西红柿(Ruby pusa 变种)收获后贮藏条件下的货架寿命
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-10-20 DOI: 10.1016/j.bcdf.2024.100455
Subhransu Sekhar Behera , Suchismita Nivedita , Himadri Tanaya Behera , Abhik Mojumdar , Badri Narayana Sahoo , Lopamudra Ray
{"title":"Bio synthesis of chitosan from shrimp shell chitin using Streptomyces griseoincarnatus RB7AG:Characterization and application as coating material to enhance shelf life of tomatoes (var. Ruby pusa) in post-harvest storgae condition","authors":"Subhransu Sekhar Behera ,&nbsp;Suchismita Nivedita ,&nbsp;Himadri Tanaya Behera ,&nbsp;Abhik Mojumdar ,&nbsp;Badri Narayana Sahoo ,&nbsp;Lopamudra Ray","doi":"10.1016/j.bcdf.2024.100455","DOIUrl":"10.1016/j.bcdf.2024.100455","url":null,"abstract":"<div><div>In this investigation, chitosan was successfully obtained from shrimp shell chitin through microbial degradation by <em>Streptomyces griseoincarnatus</em> RB7AG. The resulting chitosan showcased remarkable characteristics, including high solubility, a high degree of deacetylation, a well-defined crystalline structure, and a rough surface with minimal pores. The application of chitosan as a coating material for tomatoes demonstrated significant preservation benefits compared to commercially available chitosan. The chitosan coating proved effective in minimizing weight loss, reducing the production of reactive oxygen species (ROS), and preserving essential compounds such as anthocyanin content and antioxidant enzymes in tomatoes. Firstly, the chitosan coating served as a physical barrier, preventing moisture loss and maintaining the tomatoes' structural integrity. Secondly, the antimicrobial properties of chitosan hindered the growth of spoilage-causing microorganisms, extending the shelf life of the tomatoes. Additionally, the chitosan coating exhibited antioxidant properties, scavenging ROS and preserving the natural antioxidants in tomatoes. Furthermore, the chitosan coating facilitated controlled gas exchange, allowing optimal levels of oxygen and carbon dioxide to maintain the freshness of the tomatoes without accelerating the ripening process. With the help of the above-mentioned mechanisms, the potential of the microbially synthesized chitosan to enhance the shelf life of the tomatoes can be explained which was found better than the commercially synthesized chitosan coating. This research underscores the potential of microbially synthesized chitosan as an effective coating material but also provides insights into the intricate mechanisms involved in preserving tomatoes. The findings pave the way for innovative applications of chitosan-based coatings in the food industry, ensuring prolonged freshness and nutritional quality of perishable fruits and vegetables.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100455"},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of cooking and market classes on nutritional and antioxidant properties of dry bean flours and soluble dietary fiber-rich fractions 烹饪和市场等级对干豆粉和富含可溶性膳食纤维部分的营养和抗氧化特性的影响
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-10-11 DOI: 10.1016/j.bcdf.2024.100454
Ana M. Magallanes López , Osvaldo H. Campanella , Senay Simsek
{"title":"Effects of cooking and market classes on nutritional and antioxidant properties of dry bean flours and soluble dietary fiber-rich fractions","authors":"Ana M. Magallanes López ,&nbsp;Osvaldo H. Campanella ,&nbsp;Senay Simsek","doi":"10.1016/j.bcdf.2024.100454","DOIUrl":"10.1016/j.bcdf.2024.100454","url":null,"abstract":"<div><div>Dry beans are a rich source of proteins, starch, dietary fiber, and phenolic compounds, thus exhibiting potential health benefits. Fractionating dry beans, especially soluble dietary fiber (SDF), could be considered a valuable functional food ingredient. This study investigated the effects of pinto and black dry bean market classes and atmospheric pressure cooking on the physicochemical attributes of dry bean flours and the extraction and characterization of SDF-rich fractions. Cooking significantly (p &lt; 0.05) increased the dietary fiber content, altering the macronutrient profile. Raw flours exhibited higher levels of extractable phenols and antioxidant capacity, while cooked flours had more hydrolyzable phenols and associated antioxidant activities. Pinto beans were found to have higher levels of slowly digestible starch (23.76%) and resistant starch (5.24%) compared to black beans (20.63% and 3.22%, respectively). The SDF-rich fraction from cooked flours showed a reduced residual protein content and included pectic polysaccharides, hemicelluloses, and raffinose family oligosaccharides (RFOs), with cooking affecting their molecular weight distribution. These fractions demonstrated shear-thinning behavior and temperature-dependent viscosity. The study highlights the significant influence of market class and cooking process on the nutritional and antioxidant properties of dry beans, suggesting their potential contributions to dietary health.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100454"},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prebiotic activity of enzymatically modified pea peel dietary fiber: An in vitro study 酶解改性豌豆皮膳食纤维的益生元活性:体外研究
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-09-24 DOI: 10.1016/j.bcdf.2024.100452
Tapasya Kumari , Arup Jyoti Das , Amit Baran Das , Chagam Koteswara Reddy , Sankar Chandra Deka
{"title":"Prebiotic activity of enzymatically modified pea peel dietary fiber: An in vitro study","authors":"Tapasya Kumari ,&nbsp;Arup Jyoti Das ,&nbsp;Amit Baran Das ,&nbsp;Chagam Koteswara Reddy ,&nbsp;Sankar Chandra Deka","doi":"10.1016/j.bcdf.2024.100452","DOIUrl":"10.1016/j.bcdf.2024.100452","url":null,"abstract":"<div><div>The study examined the prebiotic index of enzymatically modified insoluble dietary fiber from pea peel by using three probiotic bacterias; <em>Lactobacillus rhamnosus</em> ATCC 7469, <em>Lactobacillus sakei</em> ATCC 15521, <em>Lactobacillus plantarum</em> ATCC 8014 and one pathogenic bacteria; <em>Escherichia coli</em> ATCC 4157. A positive value for prebiotic potential was determined which was greater than inulin, unmodified dietary fiber, and standard glucose. The 30 h of cultivation, the cell density obtained from <em>Lactobacillus rhamnosus</em> ATCC 7469 culture conducted in MRS was 7.45 ± 0.08 log CFU/mL in glucose medium and 7.37 ± 0.07 log CFU/mL in dietary fiber medium. Growth kinetics analysis showed a positive effect for <em>Lactobacillus</em> spp. in DF medium. DF could boost cell biomass and relative growth rate of probiotic bacteria. Thus, the microbiome of the colon facilitates dietary fiber fermentation by bacteria shown in <em>in vitro</em> simulated gastrointestinal model.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100452"},"PeriodicalIF":0.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of antioxidant, antidiabetic, and antimicrobial properties of hybrid mushroom strains derived through intergeneric hybridization between Pleurotus sajor-caju and Calocybe indica 评估通过红豆杉和姬松茸属间杂交获得的杂交蘑菇菌株的抗氧化、抗糖尿病和抗菌特性
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-09-08 DOI: 10.1016/j.bcdf.2024.100450
Piu Das , Arnab De , Arpita Das , Amalesh Samanta
{"title":"Assessment of antioxidant, antidiabetic, and antimicrobial properties of hybrid mushroom strains derived through intergeneric hybridization between Pleurotus sajor-caju and Calocybe indica","authors":"Piu Das ,&nbsp;Arnab De ,&nbsp;Arpita Das ,&nbsp;Amalesh Samanta","doi":"10.1016/j.bcdf.2024.100450","DOIUrl":"10.1016/j.bcdf.2024.100450","url":null,"abstract":"<div><p>Our present study aims to evaluate the biological activities of the six hybrid mushrooms (APS) obtained through the protoplast fusion technique between two mushrooms <em>Calocybe indica and Pleurotus sajor-caju</em>, in our previous study. Antioxidant activity of hybridized mushroom samples was determined by the free radical scavenging method, using DPPH radical, Superoxide radical, and Hydroxyl radical. Additionally, all the mushroom extract has shown a good amount of total phenolic content, and total flavonoid content and also has potent Ferric reducing antioxidant power. The Total phenolic content, Total flavonoid content, and Ferric reducing antioxidant power were estimated. Six constituents: gallic acid, catechin, protocatechuic acid, p-hydroxybenzoic acid, p-coumaric acid, and cinnamic acid were identified by UHPLC. The MIC values, zone of inhibition, growth kinetic, and scanning electron microscopy (SEM) were performed to establish the antimicrobial efficacy. The tested samples exhibited antimicrobial activity against selected microorganisms <em>Staphylococcus aureus</em>, <em>Klebsiella pneumoniae</em>, <em>Bacillus subtilis</em>, <em>Pseudomonas aeruginosa</em>. A clear morphological change was observed under SEM when <em>Bacillus subtilis</em> and <em>Pseudomonas aeruginosa</em> were treated with APS-4 and APS-3 mushroom extracts. The ability to inhibit carbohydrate hydrolyzing enzymes such as α-amylase and α-galactosidase has also been studied to explore antidiabetic properties. The inhibitory activity of α-glucosidase was APS-4 reflected a very prominent result with the lowest IC<sub>50</sub> value i.e.,118.058 ± 1.515, APS-2 and APS-6 showed almost similar IC<sub>50</sub> values. α – galactosidase inhibitory activity of APS-4 and APS-6 exhibit better results than other strains.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100450"},"PeriodicalIF":0.0,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brewer's spent yeast improves human gut microbiota and ameliorates clinical blood parameters: A randomized, double-blind, placebo-controlled trial 啤酒酵母能改善人体肠道微生物群并改善临床血液指标:随机、双盲、安慰剂对照试验
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-09-05 DOI: 10.1016/j.bcdf.2024.100442
Priscila Aparecida Horn , Ana Lúcia Bertarello Zeni , Marcos Edgar Herkenhoff , Luana Curbani , Gustavo Henrique Pereira Gonçalves , Camila Fatima Rutkoski , Nicole Grasmuk Israel , Eduardo Alves de Almeida
{"title":"Brewer's spent yeast improves human gut microbiota and ameliorates clinical blood parameters: A randomized, double-blind, placebo-controlled trial","authors":"Priscila Aparecida Horn ,&nbsp;Ana Lúcia Bertarello Zeni ,&nbsp;Marcos Edgar Herkenhoff ,&nbsp;Luana Curbani ,&nbsp;Gustavo Henrique Pereira Gonçalves ,&nbsp;Camila Fatima Rutkoski ,&nbsp;Nicole Grasmuk Israel ,&nbsp;Eduardo Alves de Almeida","doi":"10.1016/j.bcdf.2024.100442","DOIUrl":"10.1016/j.bcdf.2024.100442","url":null,"abstract":"<div><p>This study investigated the effects of Brewer's spent yeast (BSY) on blood clinical parameters, changes in the intestinal production of short-chain fatty acids, and microbiota composition. A double-blind, placebo-controlled, randomized clinical trial intervention study was conducted on 50 healthy volunteers for four weeks, in which participants took a pill containing 500 mg of BSY or an equivalent placebo pill containing maltodextrin. After the intervention, plasma total cholesterol level decreased, and fecal short-chain fatty acids in the form of butyric acid and acetic acid increased in the BSY group but not in the control group. Microbiome analysis by qPCR showed a higher abundance of healthy associations of <em>Lactobacillus</em> and Firmicutes in the BSY-T group, suggesting that the dietary metabolic response may depend on the specific composition of the gut microbiota. These results indicate the potential positive impact of Brewer's yeast on metabolic health and intestinal microbiota.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100442"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Eucommia ulmoides leaf extracts and caltrate on osteoblasts proliferation and differentiation 杜仲叶提取物和钙盐对成骨细胞增殖和分化的影响
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-08-30 DOI: 10.1016/j.bcdf.2024.100448
Xuan Ma , Dongli Yin , Tingting Liu , Yilei Wang , Shengcan Zou , TianYu Yang , Likang Zhao , Feng Wang
{"title":"Effects of Eucommia ulmoides leaf extracts and caltrate on osteoblasts proliferation and differentiation","authors":"Xuan Ma ,&nbsp;Dongli Yin ,&nbsp;Tingting Liu ,&nbsp;Yilei Wang ,&nbsp;Shengcan Zou ,&nbsp;TianYu Yang ,&nbsp;Likang Zhao ,&nbsp;Feng Wang","doi":"10.1016/j.bcdf.2024.100448","DOIUrl":"10.1016/j.bcdf.2024.100448","url":null,"abstract":"<div><p>Osteoporosis is a significant and escalating public health issue. It is a skeletal disorder in which there is a decrease in bone strength, resulting in a heightened susceptibility to fractures. <em>Eucommia ulmoides</em> leaves (EUL) has been traditionally employed to alleviate muscle and bone weakness. In order to investigate the induction of osteoblast proliferation and differentiation by the two EUL extracts under non-stress conditions, as well as their combined effects with Caltrate, this study examined cell proliferation, alkaline phosphatase activity, mineralization, and abundance of osteogenic differentiation-related proteins. The results demonstrated that EUL extract 1 and Caltrate intervention alone could promote osteoblast proliferation and differentiation, and their combined treatment exhibited a synergistic effect. EUL extract 2, when administered alone, was capable of enhancing osteoblast proliferation and differentiation; however, it did not exhibit a strong synergistic effect when combined with Caltrate. Therefore, administering EUL extract 1 either individually or in combination with Caltrate serve as a potential dietary supplement for osteoporosis.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100448"},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional and structural characteristic of plant protein isolates as emulsifier by ultrasound-assisted extraction: A review 超声辅助提取植物分离蛋白作为乳化剂的功能和结构特征:综述
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-08-30 DOI: 10.1016/j.bcdf.2024.100449
Abdurohman Zakki, Nita Aryanti, Hadiyanto Hadiyanto
{"title":"Functional and structural characteristic of plant protein isolates as emulsifier by ultrasound-assisted extraction: A review","authors":"Abdurohman Zakki,&nbsp;Nita Aryanti,&nbsp;Hadiyanto Hadiyanto","doi":"10.1016/j.bcdf.2024.100449","DOIUrl":"10.1016/j.bcdf.2024.100449","url":null,"abstract":"<div><p>Depletion of natural-based resources is a common problem in many countries. This worse condition is in line with the people suffering from malnutrition when consuming food. The Sustainable Development Goals (SDGs) challenge ensuring global food security. More exploration of underutilized sustainable protein resources is required to preserve the protein sources. Ultrasound-assisted extraction (UAE) is a model-promoting extraction to isolate the plant-based protein effectively. UAE is a green extraction technique that provides high-performance results with power and time variation of protein isolates. This study aims to review the impact of UAE on functional and structural characteristics of plant protein isolation (PPI). The previous review reveals the optimum condition of extraction variables, whereas the contribution of UAE in protein isolate. The mechanism of UAE focused on extracting plant protein isolates such as protein yield, solubility, water or oil holding capacity, surface hydrophobicity, foaming capacity, emulsifying activities, and zeta potential. The UAE effect successfully maintains emulsion stability by lowering surface tension and increasing protein solubility in the aqueous phase. The aggregation of protein film at the interface between hydrophilic and hydrophobic media affects its stability in obtaining homogeneous mixtures. The findings clarified that the UAE can enhance the functional characteristics of PPI to fit and proper processing in food industries and support SDGs.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100449"},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of enzymatically derived manno-oligosaccharides on the growth of select lactobacillus strains under aerobic and anaerobic conditions 酶解甘露寡糖对有氧和厌氧条件下特定乳酸菌菌株生长的影响
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-08-28 DOI: 10.1016/j.bcdf.2024.100445
Erica Di Pede , Oreoluwa Kolade , Bradley Saville
{"title":"Impact of enzymatically derived manno-oligosaccharides on the growth of select lactobacillus strains under aerobic and anaerobic conditions","authors":"Erica Di Pede ,&nbsp;Oreoluwa Kolade ,&nbsp;Bradley Saville","doi":"10.1016/j.bcdf.2024.100445","DOIUrl":"10.1016/j.bcdf.2024.100445","url":null,"abstract":"<div><p>This study highlights the ability of beta-MOS derived from coconut processing residues (copra meal) to promote the <em>in vitro</em> growth of <em>Lactobacillus</em> probiotics. Enzymatic hydrolysis conditions were manipulated to produce Low Molecular Weight (LMW) and (HMW) Manno-oligosaccharide (MOS) extracts. The LMW MOS contained more mannose and mannobiose, and the HMW MOS contained more mannotriose and higher molecular weight oligosaccharides. The growth of <em>Limosilactobacillus reuteri</em>, <em>Lactiplantibacillus plantarum</em> and <em>Lacticaseibacillus rhamnosus GG</em> on the MOS Extracts was evaluated and compared with growth on Inulin, FOS and XOS. There was significant growth of each probiotic on the MOS extracts. Probiotic growth was similar on MOS extracts and on FOS, while growth was much lower on XOS and Inulin. Probiotic growth was greater under anaerobic than under aerobic conditions. The results confirm the value of a bioactive compound from copra meal to support human and animal health, while contributing to a circular bioeconomy.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100445"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212619824000457/pdfft?md5=b4e5cdedf905d92367880fdbc04e281e&pid=1-s2.0-S2212619824000457-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancement of Candida albicans phagocytosis and inhibitory potency of Alternative Complement Pathway by an arabinoxylan extracted from Plantago ciliata Desf. Seeds and its oligosaccharides 从车前子种子中提取的阿拉伯木聚糖及其低聚糖增强白念珠菌的吞噬能力和替代性补体途径的抑制效力种子中提取的阿拉伯木聚糖及其寡糖
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-08-26 DOI: 10.1016/j.bcdf.2024.100446
Aziza Safaa Chenine , Zakaria Boual , Mohamed Didi Ould Elhadj , Noura Addoun , Reguia Mahfoudi , Aicha Khemili , Djahida Bey , Hakim Belkhalfa , Youcef Rahmani , Pascal Dubessay , Cédric Delattre , Guillaume Pierre , Philippe Michaud
{"title":"Enhancement of Candida albicans phagocytosis and inhibitory potency of Alternative Complement Pathway by an arabinoxylan extracted from Plantago ciliata Desf. Seeds and its oligosaccharides","authors":"Aziza Safaa Chenine ,&nbsp;Zakaria Boual ,&nbsp;Mohamed Didi Ould Elhadj ,&nbsp;Noura Addoun ,&nbsp;Reguia Mahfoudi ,&nbsp;Aicha Khemili ,&nbsp;Djahida Bey ,&nbsp;Hakim Belkhalfa ,&nbsp;Youcef Rahmani ,&nbsp;Pascal Dubessay ,&nbsp;Cédric Delattre ,&nbsp;Guillaume Pierre ,&nbsp;Philippe Michaud","doi":"10.1016/j.bcdf.2024.100446","DOIUrl":"10.1016/j.bcdf.2024.100446","url":null,"abstract":"<div><p>Leveraging bioactive compounds with immunomodulatory effects to boost immune functions represents a promising strategy for therapeutic intervention. The main objective of this work was to investigate the influence of the partial acid hydrolysis of an arabinoxylan extracted from <em>Plantago ciliata</em> Desf. seeds into oligosaccharides on its immunomodulatory effect. The resulting oligosaccharides and their polymer were evaluated for their potential to improve the phagocytic capacity (PC) and the phagocytic activity (PA) of polymorphonuclear neutrophils (PMNs) through the uptake of <em>Candida albicans</em> and to moderate alternative complement pathway (ACP) activation. As a result, the arabinoxylan derived from <em>P. ciliata</em> seeds (AXPCs) and its oligosaccharides (AXOPCs) significantly enhanced the PC of PMN cells, with EC50 values of 0.14 ± 0.23 and 0.12 ± 0.10 mg/mL, respectively. Zymosan used as a reference exhibited the highest PC with an EC50 0.07 ± 0.08 mg/mL. However, for PA, zymosan still demonstrated the highest activity with an EC50 of 0.22 ± 0.46 mg/mL compared to 0.33 ± 1.36 and 0.30 ± 0.74 mg/mL for AXPCs and AXOPCs, respectively. Moreover, AXPCs and AXOPCs were tested as moderator inhibitors of the complement system, showing maximum inhibition percentages of 40.11 ± 8.38% and 50.57 ± 10.45% at 1 mg/mL, with IC50 values of 1.49 ± 0.40 and 1.02 ± 0.20 mg/mL, respectively, compared to 61.52 ± 7.17% and 70.89 ± 5.78% for heparin used as a reference. These results suggest that AXPCs and AXOPCs can serve as relevant therapeutic immunomodulatory factors.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"32 ","pages":"Article 100446"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and antioxidant activity of flaxseed mucilage and evaluation of its dietary supplementation in improving calcium absorption in vivo 亚麻籽粘液的特性和抗氧化活性及其膳食补充剂在改善体内钙吸收方面的评估
Bioactive Carbohydrates and Dietary Fibre Pub Date : 2024-08-23 DOI: 10.1016/j.bcdf.2024.100444
Engy M. Akl , Rasha S. Mohamed , Sherein S. Abdelgayed , Karem Fouda , Mosaad A. Abdel-Wahhab
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