Bioactive Carbohydrates and Dietary Fibre最新文献

{"title":"Fecal fermentation and gut microbiota modulation of dietary fibre and polyphenols from Gnetum gnemon Linn. leaves","authors":"Nata Anisong ,&nbsp;Sunisa Siripongvutikorn ,&nbsp;Panupong Puttarak ,&nbsp;Santad Wichienchot","doi":"10.1016/j.bcdf.2023.100380","DOIUrl":"10.1016/j.bcdf.2023.100380","url":null,"abstract":"<div><p>The purpose of this study was to analyze the effects of <span><em>Gnetum</em><em> gnemon</em></span> var<strong>.</strong> <em>tenerum</em> leaf powder, dried using a vacuum microwave, on gut health properties<strong>.</strong><span><span> The two alternative drying conditions were 3600 Watts for 12 min (G1) and 2400 Watts for 15 min (G2) compared to the commercial Japanese green tea matcha powder (M) and the gut health effects were assessed by human fecal fermentation in a one-stage colon system. The enumeration of gut microbiota at 24 h of fermentation by </span>next generation sequencing (NGS) confirmed elevated </span><span><em>Bacteroides</em></span> levels and significantly (<em>P</em> &lt; 0.05) higher numbers of <span><em>Bifidobacterium</em></span><span> with G1 (33%) and G2 (37%) compared to M (31%). Additionally, short-chain fatty acid (SCFA) profile for acetic, propionic and butyric acids was analysed using gas chromatography-flame ionization detector (GC-FID), and especially butyric acids was significantly (</span><em>P</em> &lt; 0.05) higher with G1 (4.698 ± 0.61 mM) and G2 (2.768 ± 0.10 mM) compared to M, 1.805 ± 0.01 mM at 24 h. The <em>Gnetum</em> leaf powders G1 and G2 were investigated for promoting γ-aminobutyric acid (GABA) microbial metabolite, which was detected using liquid chromatography-mass/mass spectrometry (LC-MS/MS). Thus, <em>Gnetum gnemon</em> var. <em>tenerum</em> leaf powder could provide gut health benefits with good potential for use as a functional food ingredient in the future.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100380"},"PeriodicalIF":0.0,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48409196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bionanocomposite scaffolds based on MnS-nanorods loaded acacia-Senegal-gum hydrogels: Fabrication, characterization and biological evaluation","authors":"Hidayat Ullah ,&nbsp;Junaid Ihsan ,&nbsp;Rasha M.K. Mohamed ,&nbsp;Muhammad Aslam Khan ,&nbsp;Marvi Ghani ,&nbsp;Naseem Rauf ,&nbsp;Shafqat Ullah ,&nbsp;Asif Javed ,&nbsp;Muhammad Farooq","doi":"10.1016/j.bcdf.2023.100368","DOIUrl":"https://doi.org/10.1016/j.bcdf.2023.100368","url":null,"abstract":"<div><p><span>This study demonstrates a biocompatible nanofabrication based on novel </span><em>Acacia senegal</em><span> gum-manganese sulphide hydrogels (p(ASG)-MnS) to achieve enhanced biological venture. Here, p(ASG-MnS) were prepared in the presence of divinyl sulfone (DS) cross-linker, and then loaded with Manganese sulphide (MnS) nano-rods via </span><em>in situ</em> reduction method.</p><p><span><span>Various techniques for example, Scanning electron microscopy (SEM), Transmission electron microscopy<span> (TEM), X-Ray Diffraction (XRD) analysis, Thermogravimetric Analysis (TGA) and </span></span>Fourier Transform Infrared spectroscopy (FT-IR) was carried out to comprehensively characterize p(ASG)-MnS. The FTIR peak at position 1025 cm</span>⁻¹ clarifies the attachment of DS with the carboxylic group of ASG for successful crosslinking, whereas, the frequencies in 2900–3400 cm⁻¹ range are due Mn-(OH)₂<span> formation upon nanofabrication. The morphologically spherical p(ASG) particles with size distribution in 5–60 μm range were further loaded with MnS nanorods with size in 5–20 nm range as indicated from SEM and TEM, respectively.</span></p><p>Biomedical investigation of pristine and p(ASG)-MnS was carried out by evaluating their biocompatibility, antioxidant and antidiabetic activities.</p><p>In brief, the pristine, as well as, nanocomposites of the prepared scaffolds demonstrated remarkable biocompatibility with 0.758% and 2.386% hemolysis against p(ASG), and p(ASG)-MnS, respectively over the 400 μg/mL incorporated dose.</p><p><span>In addition, p(ASG)-MnS demonstrated notable antioxidant response obtained via multiple assays. The nanocomposite scaffold exhibit 66.91 ± 0.22 (%), and 98.40 ± 0.58 (%) DPPH and ABTS scavenging activities, whereas, pristine scaffold demonstrated 7.5 ± 0.58 (%) FRSA, and 4.40 ± 0.28 TEAC activity. Total </span>antioxidant capacity (TAC), and total reducing power (TRP) represented by the nanocomposite scaffold was 184.32 ± 2.3 μg AAE/mg, and 179.83 ± 0.1.2 μg AAE/mg, respectively to exhibit remarkable antioxidant response.</p><p>Additionally, the nanocomposite scaffolds exhibited considerable α-amylase inhibition with 16.7 ± 1.4 (%) that is greater than pristine scaffolds with 4.18 ± 0.98 (%) inhibition.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100368"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49714875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of brewers’ spent grain on cardiovascular disease risk factors in adults: Lessons learned from a pilot study","authors":"Shannon Schmidt-Combest ,&nbsp;Cynthia Warren ,&nbsp;Marley Grams ,&nbsp;Wanyi Wang ,&nbsp;Derek Miketinas ,&nbsp;Mindy Patterson","doi":"10.1016/j.bcdf.2023.100367","DOIUrl":"10.1016/j.bcdf.2023.100367","url":null,"abstract":"<div><p>The beer industry generates large amounts of leftover barley called brewers’ spent grain (BSG). Fiber-rich grains like barley are associated with ameliorating cardiovascular disease (CVD) risk factors. This randomized pilot study investigated the influence of daily BSG consumption for 8 weeks on lipid profiles, inflammation, and metabolic functions in healthy adults. Subjects (<em>n</em> = 37, 26 ± 4 y; BMI 23 ± 3 kg/m²) received muffins containing 8.3 g BSG or 0 g BSG daily for 8 weeks. Body composition, blood pressure, and fasting blood were collected at baseline and week 8. Gastrointestinal symptoms and Bristol stool scale ratings remained stable throughout the study in both groups. Dietary fiber intake increased in the BSG group (5 g/day; 26%; <em>p</em> = 0.003); however, there were no significant between-group effects on blood lipids, glucose, insulin sensitivity, C-reactive protein, body composition, or blood pressure. Consuming 8.3 g BSG for 8 weeks is well tolerated and improves dietary fiber intake but does not significantly impact CVD risk factors in this sample of healthy adults. Subject health status, sample size, and BSG flour substitution rate may support the lack of effect in the current study. Larger controlled trials are needed to understand the potential of BSG as a value-added ingredient and its impact on human health.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100367"},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46970596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel soluble powder containing high Dendrobium huoshanense polysaccharide and its in vitro hypoglycemic activities evaluation","authors":"Yuhui Pan ,&nbsp;Mengnan Wang ,&nbsp;Zhiqiang Wang ,&nbsp;Xiaojun Huang ,&nbsp;Xiaobo Hu ,&nbsp;Qin Wang ,&nbsp;Shaoping Nie","doi":"10.1016/j.bcdf.2023.100362","DOIUrl":"10.1016/j.bcdf.2023.100362","url":null,"abstract":"<div><p><span><em>Dendrobium</em><em> huoshanense</em></span><span> polysaccharide possesses a variety of biologic activities, but their high viscosity leads to poor water solubility which limit their industrialized production and practical application. In this study, two granulation techniques, spray drying and wet granulation were used to prepare the powders containing high </span><em>Dendrobium huoshanense</em> polysaccharide. The yield, polysaccharides content and solubility were investigated. The results showed that the powders containing high <em>Dendrobium huoshanense</em> polysaccharide prepared by wet granulation (DHP-WG) were more suitable for industrialized production and practical application. The optimal product was DHP-WG-70 with a granulation yield of 78.54 ± 1.02%, polysaccharides content of 70.85 ± 1.67% and dissolution time of 60.05 ± 5.02s. The hypoglycemic activity of DHP-WG and DHP was compared by <em>in vitro</em> experiments including inhibition assay for α-glucosidase, kinetics of inhibition on α-glucosidase, glucose adsorption capacity, glucose dialysis retardation index and inhibition assay for α-amylase activity. In general, DHP had better hypoglycemic activity than DHP-WG. In DHP-WGs, DHP-WG-50 and DHP-WG-70 showed better hypoglycemic activity than DHP-WG-30 and DHP-WG-90. This study provided a theoretical basis for the development and production of powders with high polysaccharides content of <em>Dendrobium huoshanense</em><span> and hypoglycemic effect in the food industry.</span></p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100362"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42799012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A controversial topic: The double edge sword of dietary β-fructans in IBD","authors":"Heather Armstrong","doi":"10.1016/j.bcdf.2023.100375","DOIUrl":"10.1016/j.bcdf.2023.100375","url":null,"abstract":"","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100375"},"PeriodicalIF":0.0,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47378949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of biocompatible amino acid-functionalized cellulose composites: Characterizations, molecular modeling, anticoagulant activity, and cytocompatibility","authors":"Sawsan Dacrory,&nbsp;Amal H. Abdel Kader,&nbsp;Mohamed Hasanin,&nbsp;Samir Kamel","doi":"10.1016/j.bcdf.2023.100372","DOIUrl":"10.1016/j.bcdf.2023.100372","url":null,"abstract":"<div><p><span><span>This study explored the anticoagulant activity of biocompatibility and </span>biodegradability<span> of all-natural composite based on cellulose cysteine </span></span>Schiff's base<span><span><span><span> composites and compared it with molecular modeling calculations. These composites were prepared through two steps: cellulose was oxidized to dialdehyde cellulose (DAC) via </span>sodium<span> periodate, followed by coupling with a different ratio of cysteine. The oxidation and coupling reactions were confirmed by studying the </span></span>chemical structures via physiochemical analysis and </span>surface morphology<span><span> via scanning electron microscope (SEM) techniques. In addition, the prepared samples' anticoagulant activity was studied by determining blood agglutination factors regarding </span>prothrombin time<span> (PT) and partial thromboplastin time (PTT) compared with the activity of native cellulose and DAC. The obtained results demonstrated that cellulose cysteine Schiff's base composites enhance the coagulation times of blood plasma, and maximum anticoagulant activities were recorded at 45, 40, and 35 μg/mL for loading of 0.4, 0.8, and 1.2 mmoL cysteine, respectively. The cytotoxicity of the prepared composites was also tested using a Vero cell (normal fibroblast cell line). Results revealed that cellulose cysteine Schiff's base composites had negligible cytotoxicity.</span></span></span></p><p><span>Additionally, the activity of the prepared composites was performed and referred to as capitulation calcium ion. Moreover, the molecular modeling of bovine thrombin complexes (PDB: </span><span>1ETT</span><svg><path></path></svg><span>) with cellulose cysteine Schiff's base was studied to confirm the functionalization of composite toward the calcium ion to prevent blood coagulation. This study suggests using cellulose cysteine Schiff's base composites as a coating in blood packs in the blood donation process.</span></p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100372"},"PeriodicalIF":0.0,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45787213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of prebiotic supplementation on the low-temperature storage stability and in vitro gastrointestinal tolerance of Bifidobacterium breve and Bifidobacterium longum in lactose and sucrose systems","authors":"Priyanka Parhi,&nbsp;Keang Peng Song,&nbsp;Wee Sim Choo","doi":"10.1016/j.bcdf.2023.100369","DOIUrl":"10.1016/j.bcdf.2023.100369","url":null,"abstract":"<div><p><span>The objective of this study was to investigate the effect of fructooligosaccharides (FOS) and inulin supplementation on the stability of </span><span><em>Bifidobacterium breve</em></span> and <span><em>Bifidobacterium longum</em></span><span> grown in lactose and sucrose systems over 12-week low-temperature storage at 4 °C. FOS and inulin supplementation in the lactose and sucrose systems improved the low-temperature storage stability of </span><em>B. breve</em> and <em>B. longum.</em> On week 12, the highest lactic (29.7 ± 0.7%) and acetic acid (28.7 ± 1.3%) concentrations were observed in <em>B. breve</em> in 2% lactose with 3% inulin supplementation. In week 12, <em>B. breve</em><span> auto-aggregation rate and hydrophobicity significantly increased in 2% lactose with 3% inulin supplementation than non-supplemented (2% lactose). At week 0, the co-aggregation of </span><em>B. longum</em> and <em>B. breve</em> with <em>E. faecalis</em> and <span><em>E. coli</em></span> significantly increased compared to non-supplemented media. However, as the storage week proceeded, the co-aggregation ability of <em>B. longum</em> and <em>B. breve</em> drastically declined. FOS and inulin supplementation in these sugar systems significantly improved hydrophobicity, auto-aggregation, and co-aggregation ability with <span><em>Enterococcus faecalis</em></span> and <em>Escherichia coli</em><span> compared to non-supplemented media. In addition, the increase in the bacterial survival rate </span><em>in vitro</em> gastrointestinal tolerance assay showed that FOS and inulin supplementation in these sugar systems improved the gastric-intestinal tolerance of <em>B. breve</em> and <em>B. longum</em>.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100369"},"PeriodicalIF":0.0,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47815419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of pH-sensitive nanocarrier-based acrylic acid-grafted-flaxseed gum for quercetin delivery for anti-cancer application","authors":"Brijesh Kumar,&nbsp;Sharad Kumar Panday,&nbsp;Pramendra Kumar","doi":"10.1016/j.bcdf.2023.100370","DOIUrl":"10.1016/j.bcdf.2023.100370","url":null,"abstract":"<div><p><span>This study deals with the fabrication and characterization of quercetin-loaded acrylic acid-grafted-flaxseed gum nanoparticles<span> (QUR@AA-g-FGS) to delivers quercetin to the targeted colonic area and to enhances anti-cancer activity. The acrylic acid-grafted-flaxseed gum (AA-g-FGS) was synthesized using ceric ammonium nitrate (CAN) as a redox initiator via the conventional method. The synthesized acrylic acid-grafted-flaxseed (AA-g-FGS) gum was also optimized through varying grafting parameters such as acrylic acid and CAN concentration, time and temperature to obtain the maximum yield of acrylic acid-grafted-flaxseed gum. The quercetin release behavior of QUR@AA-g-FGS was studied at several biological pH and the highest drug release (95%) was observed at pH 7.4 and 8 h. The quercetin release kinetic data was following the first order (R</span></span>² = 0.9842) kinetic model. The cytotoxicity of QUR@AA-g-FGS was investigated on HCT-15 cell line (cancerous human cell line) and, QUR@AA-g-FGS demonstrated outstanding toxicity toward HCT-15 cell line. Thus, the present study procures a worthwhile, nominal and ecologically sound approach toward the synthesis of QUR@AA-g-FGS for colon targeted drug delivery system.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100370"},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43631880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upregulation of tight junction-related proteins by hyaluronic acid in human HaCaT keratinocytes","authors":"Ha-Young Park ,&nbsp;Dong-Keon Kweon ,&nbsp;Jae-Kyung Kim","doi":"10.1016/j.bcdf.2023.100374","DOIUrl":"10.1016/j.bcdf.2023.100374","url":null,"abstract":"<div><p>Hyaluronic acid (HA) is a natural polysaccharide widely used in dermatology; however, HA effects on the expression of proteins related to skin barrier function and their dependence on the HA molecular weight are still limited. In this study, we treated immortalized human keratinocytes with HA samples of low and high molecular weights (LMW-HA, &lt;100 kDa and HMW-HA, &gt;500 kDa, respectively) and analyzed the expression of tight junction-forming proteins. Both LMW-HA and HMW-HA significantly increased the expression of claudin-3 and claudin-4, whereas HMW-HA also upregulated junctional adhesion molecule JAM-1. These results indicate that HA could improve the skin barrier function by inducing the expression of tight junction-related genes in keratinocytes and that the effect could depend on the molecular weight of HA fragments.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100374"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45160970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of polysaccharides from a new variety of Stevia rebaudiana","authors":"Maria Rosa T. Zorzenon ,&nbsp;Lorena G.B. Aristides ,&nbsp;Cynthia Leticia S. Cabeça ,&nbsp;Wellington F. dos Santos ,&nbsp;Giuliana C.C. Grande ,&nbsp;Laiza B. Beltran ,&nbsp;Cecília E. Mareze-Costa ,&nbsp;Antonio S. Dacome ,&nbsp;Paula G.M. Fernandes ,&nbsp;Thales R. Cipriani ,&nbsp;Silvio Claudio da Costa","doi":"10.1016/j.bcdf.2023.100371","DOIUrl":"10.1016/j.bcdf.2023.100371","url":null,"abstract":"<div><p><span><em>Stevia</em><em> rebaudiana</em></span><span><span><span> (Bert.) is a plant known worldwide for containing steviol glycosides in its leaves, high-intensity sweetener. The Stevia UEM-13 variety was developed in Brazil and is considered an elite variety for containing high levels of rebaudiodiside A, the sweetener with the best sensory profile in Stevia. However, it is necessary to investigate other metabolites of this variety, such as </span>polysaccharides<span><span><span>, which have shown functional and antiviral activities. In this sense, the objective of this work was to obtain and investigate the </span>chemical structure<span> of polysaccharides from the Stevia variety UEM-13. An aqueous extraction was performed from the dried and ground leaves and precipitation with ethanol. The precipitate was subjected to dialysis, a high-intensity and subsequently to a DEAE-cellulose column. The contents of total carbohydrates<span>, proteins, phenolic compounds, and </span></span></span>uronic acids<span> were determined during all steps. A fraction (F2) was obtained containing 50% carbohydrates with heterogeneous profile by HPSEC. The </span></span></span>monosaccharide<span><span> composition performed by GC-MS identified 35.7% arabinose and 16.5% </span>galactose and by NMR it was possible to suggest that the polysaccharide is a type II arabinogalactan (AG-II). AG-II was also found in other varieties of Stevia and has shown functional properties, which may contribute to disease prevention and health promotion.</span></span></p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"30 ","pages":"Article 100371"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46836929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}