Bioactive Carbohydrates and Dietary Fibre最新文献

{"title":"Molecular docking and GC-MS profiling of seaweed bioactive components: Unraveling antibacterial and antibiofilm activity in carbohydrate-rich extracts","authors":"Eman A. Alwaleed,&nbsp;Aya A. Alrashedi,&nbsp;Asmaa S. Abdelgeliel","doi":"10.1016/j.bcdf.2025.100516","DOIUrl":"10.1016/j.bcdf.2025.100516","url":null,"abstract":"<div><div>In this study, the antibacterial and antibiofilm activities of ethanolic and methanolic extracts of seaweed species<em>, Corallina officinalis, Padina pavonica, and Caulerpa lentillifera,</em> were systematically evaluated. Eleven clinically resistant bacterial strains, representing both Gram-positive and Gram-negative species, were tested to assess the broad-spectrum efficacy of the extracts. Phytochemical characterization using GC–MS and FTIR analyses revealed several bioactive compounds that may be responsible for the observed antimicrobial effects, including significant inhibition of biofilm formation. Among the tested samples, the methanolic extract of <em>P. pavonica</em> exhibited the most potent antibacterial activity, with a minimum inhibitory concentration (MIC) of 70 mg/mL against Streptococcus pyogenes and a minimum bactericidal concentration (MBC) of 160 mg/mL against <em>Bacillus velezensis</em>. These findings suggest that marine algae represent a valuable source of novel antimicrobial agents with potential pharmaceutical and medicinal applications. Furthermore, molecular docking results provide additional insight into the possible mechanisms of action, supporting the development of seaweed-derived compounds as promising candidates for future therapeutic interventions.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100516"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145801978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutraceutical potential of low methylated pectin derived from pectin rich agrowaste","authors":"Rajesh Kumar,&nbsp;Jagan Mohan Rao Tingirikari","doi":"10.1016/j.bcdf.2025.100518","DOIUrl":"10.1016/j.bcdf.2025.100518","url":null,"abstract":"<div><div>Increase in global population has led to significant rise in new diseases and bringing new challenges. The current treatment methods being employed are rather non-specific and have several side effects. There is a great need to find alternate, safe, prevention and treatment strategies to combat against various diseases. With global challenges such as food insecurity, increasing chronic diseases, and the pursuit of sustainable economic practices, the need for dietary fibres or nutraceuticals derived from plant waste is gaining importance. Recent studies performed on low methylated pectin (LMP) derived from pectin rich agro waste has displayed good functional properties in prevention and treatment of diseases. LMPs are generally recognized as safe, nontoxic and biocompatible. It was reported that LMPs bind to galactin-3 receptor to prevent cancer metastasis, exhibit anti-diabetic property by inhibiting α-glucosidase activity, promote anti-inflammatory activity by regulating TLR-2, IL-1β, and IL-6. LMPs exhibit antimicrobial activity by promoting the growth of beneficial bacteria, which neutralize toxins by producing short chain fatty acids. LMPs promote antioxidant activity by reducing the free radicles and reactive oxygen species. The functional properties of LMPs greatly depends on degree of methylation, source, structure, and sugar composition. Recently, LMPs are used in food industry as emulsifying, gelling, flocculation and foaming agent. This paper highlights the recent technological advancements in production, and functional properties of LMPs derived from pectin rich agro waste. In future, LMP based nutraceutical products can be developed by pharma and food industry.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100518"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation on physical modifications enhance the functional and glycaemic modulation potential of finger millet soluble dietary fiber","authors":"Kotinadham Sai Lahari ,&nbsp;Sai Babu ,&nbsp;Chagam Koteswara Reddy ,&nbsp;Tapasya Kumari","doi":"10.1016/j.bcdf.2026.100521","DOIUrl":"10.1016/j.bcdf.2026.100521","url":null,"abstract":"<div><div>This study investigates the effects of three physical modification techniques including ultrasonication (UMF), high pressure (HPMF), and high temperature (HTMF) on the physicochemical, functional, structural, and <em>in vitro</em> digestibility properties of soluble dietary fiber (SDF) extracted from finger millet. Among the treatments, ultrasonication significantly enhanced key functional properties, including water-holding capacity (19.13 g/g), swelling capacity (11.07 mL/g), oil-binding capacity (0.34 g/g), and adsorption capacities for glucose (21.24 mmol/L), cholesterol (14.55 mg/g), and sodium cholate (21.71 mg/g). In addition, ultrasonication improved the cation exchange capacity (0.87 mM/g). Structural characteriztion using Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD) revealed that ultrasonication increased surface porosity, disrupted fiber matrix, and exposed more number of active functional groups compared to high pressure and high temperature treatments. These structural modifications contributed to improved glucose diffusion retardation (35.22 %) and α-amylase inhibition (25.54 %), demonstrating improved glycaemic control potential. Ultrasonication's ability to generate localized cavitation effects led to efficient structural breakdown without requiring extreme thermal or pressure conditions. Overall, these results highlight ultrasonication as a promising, and eco-friendly approach for improving the nutritional and functional characteristics of millet-derived SDF, making it a valuable technique for development of high-quality, health-promoting functional food ingredients.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100521"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pectic polysaccharides from Açaí (Euterpe oleracea) show antitumoral effects on melanoma cell line","authors":"Suelen Cristina Soares Baal ,&nbsp;Amanda Plaça Bialli ,&nbsp;Rafaella Fernanda Angeli ,&nbsp;Luiz Claudio Fernandes ,&nbsp;Katya Naliwaiko ,&nbsp;Lucimara Mach Côrtes Cordeiro ,&nbsp;Marcia Helena Appel ,&nbsp;Fabíola Iagher","doi":"10.1016/j.bcdf.2025.100520","DOIUrl":"10.1016/j.bcdf.2025.100520","url":null,"abstract":"<div><div>Brazil has a rich biodiversity of natural compounds with high biotechnological potential that can play an essential role in preventing and treating diseases, including cancer. Açaí (<em>Euterpe oleracea</em>), a fruit native to Brazil, is known for its notable biological properties, primarily attributed to its phenolic compounds. However, despite the recognized biological activities of pectic polysaccharides from various fruits, those derived from açaí remain largely unexplored. This research evaluated the <em>in vitro</em> antitumor activity of a pectic polysaccharide fraction obtained from the açaí pulp (APF) on the murine melanoma B16F10 cell line. According to the monosaccharide composition analysis, gel permeation chromatography analysis and ¹H/¹³C HSQC-DEPT correlation map, APF is composed of type II arabinogalactan, homogalacturonan and small amounts of type I rhamnogalacturonan. The cytotoxicity of the polysaccharides was evaluated on normal BALB/c 3T3 murine fibroblast cells. Treatment with the APF fraction at concentrations of 5 and 10 μg/mL exhibited cytotoxic effects against the tumor cell line, without affecting the viability or inducing cytotoxicity in normal cells. In addition, treatment with APF at concentrations of 5 and 10 μg/mL reduced the proliferation of melanoma cells and promoted apoptosis. At 10 μg/mL, APF significantly decreased the clonogenic capacity of the tumor cell line, as indicated by a reduction in the average number of colonies, and induced cell cycle arrest. The fraction had no effect on the migratory capacity of the tumor cells. These findings highlight the promising antitumor potential of the pectic polysaccharide fraction derived from açaí fruit.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100520"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary lignocellulose and probiotic enhance immune response, intestinal morphometry, and gene expression in weaned piglets","authors":"J.M.S. Almeida ,&nbsp;L.A.F. Pascoal ,&nbsp;J.L.S. Almeida ,&nbsp;W.A. Silva ,&nbsp;J.A.L. Barbosa ,&nbsp;P.H. Watanabe ,&nbsp;R.R. Guerra ,&nbsp;P.E.N. Givisiez ,&nbsp;D.B. Campos","doi":"10.1016/j.bcdf.2026.100534","DOIUrl":"10.1016/j.bcdf.2026.100534","url":null,"abstract":"<div><div>This study evaluated the immune response, intestinal morphology, and gene expression of weaned piglets fed diets with lignocellulose and probiotics. Forty piglets weaned at 21 days of age and with an initial weight of 6.81 ± 0.45 kg were distributed in a randomized block design, with four treatments and five replicates per treatment. The treatments were: DC: control diet; DL: diet with 1% lignocellulose; DP: diet with 0.2% probiotic; DLP: diet with 1% lignocellulose and 0.2% probiotic. Performance and fecal score were not affected by dietary inclusion of lignocellulose and probiotic. The group supplemented with DLP had the highest IgM and IgG. IgA was higher in DLP compared with DC and DL (P &lt; 0.05). DL, DP and DLP increased duodenum and ileum villus height (VH), while jejunum crypt depth (CD) was smaller and VH/CD ratio was better. Jejunum VH was higher in animals fed DLP. Higher butyrate levels were detected in the cecal contents of piglets fed DL and DP, and higher valerate levels in piglets fed DP (P &lt; 0.05). Interleukin 1β expression was higher in animals fed DL and Muc2 gene expression was higher in animals fed DP. Dietary inclusion of 1% lignocellulose, 0.2% probiotic or the combination of lignocellulose and probiotic were associated with changes in immune markers and short-chain fatty acid profiles, gene expression and intestinal morphology in weaned piglets.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100534"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147802619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Relative Ordered Structure of Polysaccharide: a case study on polysaccharide characterization from Gymnadenia conopsea","authors":"Junqiao Wang,&nbsp;Chengxi Feng,&nbsp;Hui Yan,&nbsp;Zhe Wang,&nbsp;Yajie Wang,&nbsp;Junyi Yin,&nbsp;Shaoping Nie","doi":"10.1016/j.bcdf.2025.100519","DOIUrl":"10.1016/j.bcdf.2025.100519","url":null,"abstract":"<div><div>Polysaccharide, one of the major bioactive components in food materials, is hard to be characterized duo to complex structures. Previous theoretical framework of “relative ordered structure of the polysaccharide” has been well-documented in several mushroom polysaccharides but have not been demonstrated in plant bioactive polysaccharides. This study utilized this theory to guide fractionation and characterization of polysaccharide from tubes of <em>Gymnadenia conopsea</em> (<em>G. conopsea</em>). Two polysaccharides were extracted and characterized with regard to molecular weight, monosaccharide composition, substitution position, linkage patterns, and sequence. Results showed that two polysaccharide fractions showed distinctive structures. One was an O-acetyl-glucomanan containing →4)-β-Man<em>p</em>-(1→ and →4)-β-Glc<em>p</em>-(1→ as main chain structure and mono-substituted with acetyl groups at <em>O</em>-2, <em>O</em>-3 or <em>O</em>-6 position. The other was an α-glucan comprising backbone structure of →4)-α-Glc<em>p</em>-(1→ with branch substituted at C-6 and C-3 and α-Glc<em>p</em>-(1→ as the side chains. Altogether, this findings enrich the definition of “relative ordered structure of the polysaccharide” regarding plant polysaccharide, and was also the first study to fully understand the chemistry of such bioactive polysaccharides in <em>G. conopsea</em>.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100519"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of quantitative and qualitative changes in the composition of polysaccharides of Fomitopsis betulina at different stages of maturity of mushroom fruiting bodies","authors":"Lidiia Panchak ,&nbsp;Semen Khomyak ,&nbsp;Ivan Korabel ,&nbsp;Alina Zyn ,&nbsp;Olga R. Vrubel ,&nbsp;Alexandru Rotaru ,&nbsp;Volodymyr Antonyuk","doi":"10.1016/j.bcdf.2026.100535","DOIUrl":"10.1016/j.bcdf.2026.100535","url":null,"abstract":"<div><div>In this work lipophilic substances and polysaccharides from fruiting bodies <em>Fomitopsis betulina</em> (Bull.) B.K. Cui, that were collected at different stages of its development (young, mature and overripe) were investigated. The conditions of extraction water-soluble and alkali-soluble polysaccharides, their quantitative content and some physicochemical properties of the obtained substances were studied. The bulk of the lipophilic extract consists of higher fatty acids. Moreover, with the aging of fruit bodies, the percentage content of saturated fatty acids (palmitic and stearic) increases, and unsaturated (linoleic and linolenic) decreases. Squalene content decreases from young to old fruiting bodies, while ergosta-5,7,22-trien-3-ol content increases. The main mass of the fruiting body consists of carbohydrates in the composition of polysaccharides of various nature. Among them, alkali-extracted hemicellulose A predominates, and its content increases ≈2.5 times as the fruit bodies age and makes up more than 70% of their mass in overripe fruit bodies. In the case of water-soluble polysaccharides, changes are observed both in the appearance of the product obtained, and there is a significant decrease in its molecular weight (from 1500 kDa to 120 kDa). Examination of the FTIR spectra of water-soluble polysaccharides suggests that the possible cause of such changes is the formation of covalent complexes of these polysaccharides with proteins and phenolic compounds (most likely melanin). The molecular weight of pectin substances also decreases as the fruit bodies age from 180 kDa to 30 kDa.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100535"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147802620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revealing the interaction mechanisms of characteristic aroma compounds in apples (Malus × domestica) by S-curve modeling, molecular docking, and molecular dynamics simulation","authors":"Ning Ma ,&nbsp;Jiancai Zhu ,&nbsp;Heng Wang ,&nbsp;Bingjian Shen ,&nbsp;Michael C. Qian ,&nbsp;Zuobing Xiao","doi":"10.1016/j.bcdf.2026.100523","DOIUrl":"10.1016/j.bcdf.2026.100523","url":null,"abstract":"<div><div>The aroma of apples is one of the major sensory characteristics to evaluate the quality of apples. The mechanism for perceiving the aroma of apples is currently unclear. In this study, the interactions between the aroma compounds and olfactory receptors were explored by the S-curve modeling, molecular docking, and molecular dynamics simulation (MDS) technology. Hexyl acetate and β-damascenone(D = 0.46),hexyl acetate and phenethyl alcohol (D = 0.15), linalool and trans-2-hexenal (D = 0.30) etc., have synergistic effects. The molecular docking results revealed noticeable changes in the stability and affinity between the binary and single compounds combined with olfactory receptors (OR1A1 and OR2W1). In addition, molecular dynamic simulation (MDS) analysis indicated that the hydrogen bonding residues of the OR2W1-hexyl acetate were changed from ASN155 to TRP149 and ASN65 after the addition of β-damascenone. Similarly, the hydrophobic interactions of the system were increased, which played an indispensable role in forming a stable ternary system between β-damascenone-hexyl acetate and OR2W1. Meanwhile, the binding free energy decreased from −36.69 kcal/mol (hexyl acetate- OR2W1) to −37.7 kcal/mol (β-damascenone-hexyl acetate-OR2W1), which showed that the new ternary system has better stability. The results provided a theoretical basis and technical guidance for improving apple flavor and its products.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"35 ","pages":"Article 100523"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semisynthetic and amylase-treated Taraxacum officinale galactans: Combat colorectal cancer with cytokine modifier response","authors":"Jilan A. Nazeam ,&nbsp;Ian Black ,&nbsp;Varughese A. Mulamoottil ,&nbsp;Ahmed F. Hikal ,&nbsp;Ahmed Esmat ,&nbsp;Temesgen Samuel ,&nbsp;Dilip Reddy Gunturu ,&nbsp;Parastoo Azadi","doi":"10.1016/j.bcdf.2025.100492","DOIUrl":"10.1016/j.bcdf.2025.100492","url":null,"abstract":"<div><div>Polysaccharides are naturally abundant, biodegradable, and cost-effective sustainable biomaterials. However, their limited pharmacodynamic properties often hinder clinical efficacy. Hence, structural modifications of polysaccharides can enhance their therapeutic efficacy in response to application demands. In this study, a galactan polysaccharide (TOP₅₀) was purified from <em>Taraxacum officinale</em>, and three derivatives were prepared by sulfation (STOP₅₀), acetylation (ACTOP₅₀), and enzymatic hydrolysis using amylase (TOP_50am). The physicochemical properties were investigated using gas chromatography, size-exclusion chromatography, linkage analysis, infrared spectroscopy, scanning electron microscopy, and ¹H NMR spectroscopy, alongside the determination of the degree of substitution (DSS). The cytotoxic activities of the native and modified polysaccharides were evaluated against colorectal cancer cell lines (HT-29, HCT-116, and RKO), and their immunomodulatory effects were assessed by measuring cytokine levels (IL-6, IL-8, IL-10, and IL-12). Native TOP₅₀ (50 kDa) was identified as a pectic galactan with a chain of 4-linked glucoses (4-Glc), 3,6-linked galactose (3,6-Gal), terminal galactopyranosyl (t-Gal), and glucopyranosyl (t-Glc) residues. Among the derivatives, STOP₅₀ exhibited the most pronounced cytotoxic effect on RKO cells. Both STOP₅₀ and TOP_50am markedly suppressed the expression of pro-inflammatory cytokines IL-8 and IL-10 while significantly enhancing IL-12 production. Remarkably, TOP_50am induced a 15-fold upregulation of IL-12, indicating its potent immunostimulatory effects. These findings highlight the potential of structurally modified <em>T. officinale</em> galactans as multifunctional anticancer agents, supporting their potential in colorectal cancer therapy. The elucidated structure–activity relationships serve as a pivotal basis for developing polysaccharide-based therapeutics aimed at modulating tumor growth and regulating immune responses.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"34 ","pages":"Article 100492"},"PeriodicalIF":3.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144892905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microencapsulation of Fridericia chica extract: stability, anthocyanin retention, and antioxidant properties for food and therapeutic applications","authors":"Vitória Ribeiro Garcia de Figueiredo Muniz ,&nbsp;Ailane Souza de Freitas ,&nbsp;Luan da Silva Dias Rabelo ,&nbsp;Luís Felipe Perdigão Rodrigues ,&nbsp;Karina Rodrigues Honorato ,&nbsp;Ana Carolina Rorato ,&nbsp;Ana Lúcia Tasca Gois Ruiz ,&nbsp;Ilza Maria de Oliveira Sousa ,&nbsp;Luciana Igarashi-Mafra ,&nbsp;Mary Ann Foglio ,&nbsp;Alvaro Luiz Mathias ,&nbsp;Marcos R. Mafra","doi":"10.1016/j.bcdf.2025.100483","DOIUrl":"10.1016/j.bcdf.2025.100483","url":null,"abstract":"<div><h3>Relevance</h3><div><em>Fridericia chica</em> (Bonpl.) L.G. Lohmann (syn. <em>Arrabidaea chica</em> Verlot) is a medicinal plant traditionally utilized by Indigenous communities and local populations in the Amazon and tropical South America for its antioxidant, anti-inflammatory, and anticancer activities, attributed to its anthocyanin-rich composition.</div></div><div><h3>Aim of the study</h3><div>To enhance aqueous infusion extraction of processed <em>F. chica</em> leaves to maximize anthocyanin content and stabilize bioactive compounds through microencapsulation via spray drying.</div></div><div><h3>Materials and methods</h3><div>Mineral water acidified with varying concentrations of Tahiti lemon juice was used to extract bioactive compounds. The extract with the highest anthocyanin content was microencapsulated using maltodextrin or Arabic gum as protective matrices. High-Performance Liquid Chromatography (470 nm detector) identified key anthocyanidins (hydroxycarajurone, carajurone, carajurin). Total phenolic compounds (TPC), total flavonoid compounds (TFC), and antioxidant properties (ABTS, DPPH, FRAP) were assessed over 180 days under refrigerated (4 °C) and room temperature (25 °C) storage conditions.</div></div><div><h3>Results</h3><div>The extract microparticles (FEC, control) showed significant degradation in bioactive content (88 % reduction in TPC, 35 % in TFC). Microencapsulation improved stability: Microcapsules with maltodextrin (FEMM) exhibited a 7.15 % loss of total phenolic content (TPC) and a 10.22 % loss of total flavonoid content (TFC), whereas microcapsules with gum Arabic (FEMA) showed minimal loss of TPC (0.74 %) and an 11.66 % reduction of TFC. Refrigeration mitigated degradation, and Arabic gum had better-preserved antioxidant activity than maltodextrin under both conditions.</div></div><div><h3>Conclusions</h3><div>Microencapsulation significantly enhanced the stability of <em>F. chica</em> bioactive compounds, with Arabic gum outperforming maltodextrin. These powders demonstrate high potential as functional food ingredients, offering stability, antioxidant preservation, and suitability for extended storage.</div></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"34 ","pages":"Article 100483"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}