Journal of the Mechanical Behavior of Biomedical Materials最新文献

{"title":"Elastic moduli and strain-dependent lateral strain to axial strain ratio in semi-dilute polyacrylamide hydrogels","authors":"Satya Pal ,&nbsp;Thomas E. Angelini ,&nbsp;Abir Bhattacharyya","doi":"10.1016/j.jmbbm.2025.107244","DOIUrl":"10.1016/j.jmbbm.2025.107244","url":null,"abstract":"<div><div>Regulating elastic modulus of basic synthetic hydrogels, such as polyacrylamide, is crucial for their application in various fields of biotechnology. However, the measurement of elastic modulus and stress-strain response under different deformation modes is challenging in soft and fragile hydrogels. In this study, a non-contact, 2-dimensional digital image correlation (2D-DIC) technique is used to measure tensile and simple shear stress-strain responses of fully swelled polyacrylamide hydrogels at semi-dilute concentrations, over strain rates ranging between 10⁻³-10⁻¹/s. The measured strain fields exhibit uniformity across all the deformation modes up to threshold strain levels. The elastic moduli were found to be strain-rate insensitive, except at small strains for 10⁻¹/s due to strain acceleration and inertia of the specimen. The <em>E</em> and <em>G</em> determined from the initial slopes of stress-strain responses of lower strain-rate experiments followed De Genne's <em>c</em>^9/4 power law scaling with equilibrium gel concentrations. The Poisson's ratio determined from the measured axial and lateral strains at small strains was found to closely match with the Poisson's ratio determined from <em>E/G</em>, indicating that the gels follow linear elasticity for nearly incompressible solids at small strains, but deviate from linear elasticity and becoming compressible at higher tensile strains leading to nonlinearity in tensile stress-strain response marked by reduction in instantaneous tensile modulus. The simple shear stress-strain response remains linear throughout. Finally, a polymer physics-based explanation connecting hydrogel concentration, mesh size and elastic moduli is proposed to explain strain-dependent evolution of stresses in semi-dilute polyacrylamide hydrogels for different deformation modes. Therefore, design of technologies using hydrogels must consider active deformation mode.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107244"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical evaluation of shape-optimized CAD/CAM magnesium plates for mandibular reconstruction","authors":"Philipp Ruf ,&nbsp;Kilian Richthofer ,&nbsp;Vincenzo Orassi ,&nbsp;Claudius Steffen ,&nbsp;Georg N. Duda ,&nbsp;Max Heiland ,&nbsp;Sara Checa ,&nbsp;Carsten Rendenbach","doi":"10.1016/j.jmbbm.2025.107222","DOIUrl":"10.1016/j.jmbbm.2025.107222","url":null,"abstract":"<div><div>Magnesium CAD/CAM miniplates are a promising alternative to titanium plates for mandibular reconstruction. However, gas formation is an inherent part of the magnesium degradation process, and thus, the quantity of magnesium used in fixation scenarios should be limited. Previous studies described several strategies to limit material volume, such as plate thickness reduction and shape-optimization. In particular, shape-optimization has been described as a strategy to limit material volume while maintaining mechanical integrity.</div><div>In consequence, the present study compared a shape-optimized CAD/CAM magnesium miniplate with standard CAD/CAM magnesium miniplates of varying thicknesses using a biomechanical finite element model. A single-segment mandibular reconstruction was chosen as the investigative scenario, evaluated under different biting tasks to assess the different plate shapes.</div><div>The shape-optimized magnesium plate demonstrated similar primary fixation stability compared to standard CAD/CAM magnesium miniplates, despite having reduced plate material and surface area. Shape optimization could help minimize magnesium volume and surface area to mitigate the issue of gas formation during the degradation process <em>in vivo</em> while maintaining biomechanical performance comparable to common CAD/CAM miniplates.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107222"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145263114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of adipose and muscle tissue thickness on skeletal muscle echo intensity and passive shear modulus: An ultrasound elastography approach","authors":"Heinrich Leon Souza Viera,&nbsp;Fábio Juner Lanferdini","doi":"10.1016/j.jmbbm.2025.107253","DOIUrl":"10.1016/j.jmbbm.2025.107253","url":null,"abstract":"<div><div>Although the growing studies investigating muscle echo intensity (EI) and shear modulus, little is known about the effects of adipose tissue thickness (ATT) on these measures. We investigated whether ATT influences the EI and shear modulus measurements of the human tibialis anterior superficial (TA_superficial) and deep (TA_deep) compartments. Ultrasound measurements were taken from the TA at rest, near the highest cross-sectional area, in ten physically active adults in the following conditions: without fat layers and with one and two fat layers. The EI and shear modulus of both TA_superficial and TA_deep were determined, and the best-fit regression model was calculated to assess the influence of ATT on EI and shear modulus. A repeated measures ANOVA were adopted to investigate the differences in EI and shear modulus in the different fat layers. The ATT was seen to affect the EI of both TA_superficial (R² = 0.58; p &lt; 0.001) and TA_deep (R² = 0.44; p &lt; 0.001). When the thickness of TA_superficial was summed with ATT, the EI of TA_deep was also affected but to a less extent (R² = 0.25; p = 0.004). No significant influence of ATT on shear modulus was seen for both TA compartments (p ≥ 0.061). While EI decreased in both TA compartments (p &lt; 0.05), the repeated measures ANOVA revealed that only TA_deep shear modulus decreased with the addition of two fat layers (p = 0.005). Corrective formula for EI measurements was determined. Thus, while skeletal muscle EI measurements should be corrected for the thickness of subcutaneous adipose tissue as well as the depth of region of interest, shear modulus does not.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107253"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145440284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health monitoring of NiTi endodontic instruments using acoustic Emission: Spectral indicators for predictive damage detection","authors":"Jeanne Davril ,&nbsp;Romain Hocquel ,&nbsp;Marin Vincent ,&nbsp;Andrea Cappella ,&nbsp;Rémy Balthazard ,&nbsp;Éric Mortier ,&nbsp;Adrien Baldit ,&nbsp;Rachid Rahouadj","doi":"10.1016/j.jmbbm.2025.107246","DOIUrl":"10.1016/j.jmbbm.2025.107246","url":null,"abstract":"<div><div>Nickel-titanium (NiTi) endodontic instruments, also known as files, are widely used in root canal treatments due to their superelastic and shape memory properties. However, their unpredictable failure remains a major concern in clinical practice. In this study, acoustic emission (AE) monitoring is used to assess tool wear and detect early-stage damage in real-time. By segmenting the AE frequency spectrum into four bands corresponding to the sensor's sensitivity range (195–742 kHz), high- and low-frequency acoustic energy indicators are defined. The ratio of high-to low-frequency acoustic energy—termed AEDI—is proposed as a damage indicator associated with the initiation and propagation of microcracks. Its evolution during sequential blocks of use is analyzed for about ten instruments. In parallel, the number of acoustic events and the maximum penetration force are recorded and analyzed. The analysis reveals mechanical and acoustic instabilities that can inform the development of early damage detection criteria. Two predictive approaches are proposed: one based on the cumulative high-frequency AE energy (an energy threshold criterion), and another based on the progressive amplitude and recurrence of mechanical and acoustic instabilities (an incremental criterion). The cumulative AEDI-based criterion considers the total energy of high-frequency signals exceeding a defined threshold, and generally predicts damage later, after an average of 5.81 blocks (SD = 0.92). In contrast, the incremental criterion, which is based on changes in maximum force drop and AEDI increases observed at the end of each block, provides earlier warnings, with an average of 3.75 blocks (SD = 1.16). These findings lay the groundwork for the development of a real-time predictive maintenance method for NiTi endodontic files, aimed at enhancing procedural safety and instrument reliability.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107246"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145403505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the fluoride concentration in electrolyte on adhesion of an apatite layer formed on an anodized zirconium surface","authors":"Toshiki Miyazaki,&nbsp;Masaki Noguchi,&nbsp;Jin Nakamura","doi":"10.1016/j.jmbbm.2025.107206","DOIUrl":"10.1016/j.jmbbm.2025.107206","url":null,"abstract":"<div><div>Zirconium is used clinically as a material for hard-tissue repair because it has excellent corrosion resistance, low magnetic susceptibility, and low cytotoxicity. Bone-bonding ability is required to stably fix zirconium implants in bone, and anodization in a fluoride solution has been proposed as a method to achieve this. Because the corrosion reaction rate and surface crystalline phase change according to the fluoride concentration, it is assumed that the fluoride concentration in the electrolyte will affect bone bonding and mechanical properties. However, few studies have investigated this. In this study, zirconium was anodized in an electrolyte containing 0–1 M NH₄F, and apatite formation in a simulated body fluid was investigated for in vitro evaluation of bone bonding. Adhesion of the apatite layer to the substrate was also investigated. Differences in the NH₄F concentration had a negligible effect on the apatite formation ability of zirconium. However, adhesion was greatly affected by the fluorine concentration, with an intermediate concentration of 0.1 M resulting in the best adhesion. Adhesion was correlated with surface roughness of the anodized surface.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107206"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing glaucoma research with multiphysics continuum mechanics modelling: Opportunities and open challenges","authors":"Daniel Sebastia-Saez ,&nbsp;Jinyuan Luo ,&nbsp;Mengqi Qin ,&nbsp;Tao Chen ,&nbsp;Cynthia Yu-Wai-Man","doi":"10.1016/j.jmbbm.2025.107240","DOIUrl":"10.1016/j.jmbbm.2025.107240","url":null,"abstract":"<div><div>This review examines the emerging role of mechanistic mathematical models based on continuum mechanics to address current challenges in glaucoma research. At present, the advent of Artificial Intelligence and data-based models have resulted in significant progress in drug candidate screening, target identification and delivery optimization for glaucoma treatment. Physics-based models on the other hand offer mechanistic insight by modelling fundamental physical knowledge. Mechanistic models, and specifically those based on continuum mechanics, have the potential to contribute to a better understanding of glaucoma through the description of intraocular fluid dynamics, mass and heat transfer, and other basic physical phenomena. So far, these models have expanded our understanding of ocular fluid dynamics, including descriptions of fluid flow profiles, within the anterior chamber of the eye under glaucomatous conditions. With the ongoing development of multiphysics modelling frameworks, there is increasing potential to apply these tools to a wide range of current challenges within the field of glaucoma. These challenges include glaucoma drainage devices, minimally invasive surgical procedures, therapeutic contact lenses, laser-based interventions like peripheral iridotomy, and the design and optimization of biodegradable drug-releasing intracameral implants, which support patient-specific strategies for glaucoma diagnosis and treatment.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107240"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal characterization of intracranial biomechanics in a 3D biofidelic head surrogate","authors":"Ahmed A. Alshareef ,&nbsp;J. Sebastian Giudice ,&nbsp;Daniel F. Shedd ,&nbsp;Yuan-Chiao Lu ,&nbsp;Curtis L. Johnson ,&nbsp;Dzung L. Pham ,&nbsp;Matthew B. Panzer","doi":"10.1016/j.jmbbm.2025.107250","DOIUrl":"10.1016/j.jmbbm.2025.107250","url":null,"abstract":"<div><div>Rapid head motion causes the brain to deform, which may lead to acute and chronic consequences to normal brain health and function. Since the risk and severity of brain injury correlates with brain strain, computational and physical models of the brain response to impact are commonly used to assess risk and evaluate safety devices <em>in silico</em>. Most physical head surrogates that are used for equipment evaluation, however, are simplified and lack internal measures of brain deformation, relying instead on the interpretation of the resulting head kinematics to predict injury. Developing a more biofidelic physical brain surrogate to improve brain injury risk assessments requires the use of experimental brain motion data. Two techniques, sonomicrometry and tagged magnetic resonance imaging (tMRI), have been independently developed to characterize the <em>in situ</em> and <em>in vivo</em> brain response. Combining data acquired from both techniques can leverage the advantages of each method while alleviating the limitations. The objectives of this study were to create a head surrogate with realistic intracranial geometry and brain simulant for use in multimodal brain deformation experiments. Six gel simulants were tested using shear rheometry, with Sylgard 527 chosen as the best simulant for this study. The headform was created using the average geometry from an MRI template of 20 healthy volunteers, and was tested under non-injurious loading conditions using tMRI and sonomicrometry. The prototype headform showed good contrast in T1-weighted MRI and captured similar strain patterns when compared to the <em>in vivo</em> human response, although maximum principal strains (MPS) were approximately double what is measured <em>in vivo</em>. The two techniques showed good correspondence in brain motion response with trade-offs in temporal resolution and measurement density. Both techniques also showed similar displacement and strain magnitudes with a finite element simulation of the headform. Future studies will focus on including a more realistic sliding condition between skull and brain, as well as optimizing the material properties to better match the <em>in vivo</em> and <em>in situ</em> data.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107250"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vat photopolymerization of Nb2O5-Doped 3Y-TZP ceramics: Correlation between microstructure, mechanical properties, and aging resistance","authors":"Zhiquan Huang ,&nbsp;Yang Sheng ,&nbsp;Li Wang ,&nbsp;Yannan Cao ,&nbsp;Rui Dou ,&nbsp;Fangyong Zhu","doi":"10.1016/j.jmbbm.2025.107209","DOIUrl":"10.1016/j.jmbbm.2025.107209","url":null,"abstract":"<div><div>In this study, 3 mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP) ceramics with four levels of Niobium pentoxide (Nb₂O₅) doping (0, 0.3, 0.6, and 1.2 wt%) were fabricated using vat photopolymerization (VPP) and subsequently sintered at 1500 °C. The influence of Nb₂O₅ doping on the phase composition, microstructure, mechanical properties, and hydrothermal aging behavior of the ceramics was investigated. All ceramic pastes showed similar rheological behavior, and no significant difference were observed in shrinkage during sintering. X-ray diffraction revealed an increase in monoclinic phase content with increasing Nb₂O₅ doping (from 1.03 wt% to 37.60 wt% m-ZrO₂). SEM analysis showed grain growth from 0.433 to 0.558 μm with increasing dopant content. Mechanical testing revealed that low Nb₂O₅ doping (0.3 wt%) significantly improved fracture toughness (from 4.36 to 7.52 MPa m¹/²), while higher doping levels led to a decline in flexural strength (from 999.68 to 380.23 MPa) and hardness (from 12.71 to 9.51 GPa). Accelerated aging tests (134 °C/0.2 MPa, for up to 50 h) demonstrated that Nb₂O₅ addition promoted t→m transformation, increasing monoclinic content and surface roughness, ultimately reduced aging stability. These results highlight a trade-off between improved toughness and hydrothermal degradation in Nb₂O₅-doped 3Y-TZP ceramics prepared by VPP.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107209"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fused filament fabrication manufactured biological scaffolds: An investigation of mechanical properties by using the Taguchi method and machine learning techniques","authors":"Idil Tartici ,&nbsp;Paulo Bartolo","doi":"10.1016/j.jmbbm.2025.107215","DOIUrl":"10.1016/j.jmbbm.2025.107215","url":null,"abstract":"<div><div>Tissue engineering scaffolds are three-dimensional, biocompatible, biodegradable, and porous structures designed to support cell attachment, proliferation, and differentiation, leading to new tissue formation. Designing optimal scaffolds is complex, requiring the optimisation of various physical, chemical, and biological properties, which are cell- or tissue-dependent. For hard tissue applications such as bone, compressive strength is a critical property and can be adjusted by modifying printing conditions. The mechanical properties of scaffolds produced using different microstructural polymers (semi-crystalline and amorphous) depend on parameters that significantly impact filament extrusion and the crystallisation process. This study investigates the effect of key process parameters (printing temperature, printing speed, and flow) on scaffold mechanical properties using the Taguchi method. Three biocompatible polymers with different microstructures—polycaprolactone, polylactic acid, and polyethylene terephthalate glycol—were examined. Results show a high correlation between process parameters and compressive strength using the Taguchi method, but prediction accuracy remained low. Therefore, four machine learning algorithms—Random Forest (RF), Support Vector Regression (SVR), K-Nearest Neighbor (K-NN), and Gradient Boosting Regression (GBR)—were applied to enhance predictive performance. Notably, the RF and GBR algorithms achieved approximately 99 % prediction accuracy when evaluated on the test dataset.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107215"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical characterisation of hand first dorsal interosseous muscle during gripping","authors":"Simon Vauthier ,&nbsp;Christophe Noël ,&nbsp;Nicla Settembre ,&nbsp;Emmanuel Foltête ,&nbsp;Jérôme Chambert ,&nbsp;Emmanuelle Jacquet","doi":"10.1016/j.jmbbm.2025.107072","DOIUrl":"10.1016/j.jmbbm.2025.107072","url":null,"abstract":"<div><div>Prolonged exposure to vibrations from handheld tools can result in various disorders. Understanding how vibrations propagate through the hand is a key area of research involved in preventing these disorders. Within this, it is essential to grasp the mechanical behaviour of hand intrinsic muscles, especially as their properties may change during gripping due to muscular contraction. In order to achieve this objective, a homemade setup was elaborated with a view to measuring the mechanical characteristics of the first dorsal interosseous (FDI) muscle, which is located between the thumb and index finger. The apparatus featured quasi-static indentation, dynamic mechanical analysis (DMA), and shear wave elastography to investigate muscle hyperelastic, viscoelastic, and anisotropic properties, respectively. Measurements were conducted on 27 volunteers with grip instructions ranging from 0 to 40% of their maximal grip strength. The use of repeated measures analysis of variance and the computation of cross-correlations between the proposed measurement techniques unveiled that grip forces significantly modulate the mechanical behaviour of the FDI muscle. In addition, our results emphasised that the FDI muscle stiffened as grip force increased, primarily in the direction longitudinal to muscle fibres. The muscle static stiffness also rose non-linearly with the indenter penetration, thus exhibiting the hyperelastic behaviour of living tissues. The muscle dynamic stiffness was found to be strongly reshaped by vibration frequencies. It remained roughly constant up to around 100 Hz (when no grip), then climbed steeply. Grip force revealed its greatest influence on the muscle dynamic stiffness for vibrations with frequencies ranging from 20 Hz to approximately 300 Hz: the greater the grip force, the higher the dynamic stiffness. Furthermore, the FDI muscle was shown to exhibit a four- to six-fold increase in mechanical power dissipation between 20 Hz and 80 Hz when the handle was gripped at the maximum tested force, in comparison to no grip. Elevating grip forces increased vibration dissipated power within the hand muscles, thereby arguably leading to what are possibly the foremost vibration-induced risks.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"173 ","pages":"Article 107072"},"PeriodicalIF":3.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}