Journal of the Mechanical Behavior of Biomedical Materials最新文献

{"title":"Mechanical behavior of torsional honeycomb implants during mastication","authors":"Qiwen Ding ,&nbsp;Jinghu Yu ,&nbsp;Yumin Yang ,&nbsp;Shanhua Qian ,&nbsp;Fangyong Zhu ,&nbsp;Haifeng Xu","doi":"10.1016/j.jmbbm.2025.107046","DOIUrl":"10.1016/j.jmbbm.2025.107046","url":null,"abstract":"<div><div>Dental implant technology addresses masticatory dysfunction caused by tooth loss, with honeycomb structures emerging as promising candidates due to their exceptional energy absorption properties. This study systematically investigates the mechanical performance of titanium alloy honeycomb implants featuring variable twisted angles (0°–180°), aiming to optimize implant design for improved stress distribution in peri-implant bone tissue. Combined with finite element (FE) simulation and an in-vitro experimental platform based on a masticatory robot, the mechanical response of the implant under static compression and chewing different textures of food were analyzed. The results demonstrated an inverse relationship between torsional angle and both relative density and energy absorption capacity. Low-torsion configurations (≤60°) exhibited superior performance, reducing stress concentrations at thread roots and tails by 1.3–5.3 % compared to conventional designs under single axial load, while reducing by 1.5–7.2 % under combined load. The maximum strain at implant-bone interface was reduced by 1.6–3.4 % under single load and 8.9–14 % under combined load through the geometric torsion of the internal honeycomb structure, respectively. In-vitro test results showed that the low-torsion structure (&lt;90°) was more advantageous in reducing mechanical stimulation of bone tissue during chewing hard and brittle food. These findings highlight torsional honeycomb designs as a dual-functional solution combining biomechanical compatibility with structural resilience, providing actionable insights for next generation dental implant optimization.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"169 ","pages":"Article 107046"},"PeriodicalIF":3.3,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143924517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the influence of sol-gel bioactive glass 92S6 P123 on 3D-Printed scaffold fabrication","authors":"Théodore Berthelot ,&nbsp;Ronan Lebullenger ,&nbsp;Damien Brézulier ,&nbsp;Sylvie Tricot ,&nbsp;Sandrine Cammas-Marion ,&nbsp;Bertrand Lefeuvre ,&nbsp;Anita Lucas","doi":"10.1016/j.jmbbm.2025.107041","DOIUrl":"10.1016/j.jmbbm.2025.107041","url":null,"abstract":"<div><div>Additive manufacturing techniques for scaffold fabrication have shown remarkable potential in tissue engineering and regenerative medicine. In this study, a novel approach involving a composite material consisting of an association of sol-gel bioactive glass, 92S6 P123, with polylactic acid (PLA) was explored to create intricate three-dimensional (3D) scaffolds. The main objective was to analyze the impact of incorporating bioactive glass 92S6 P123 on the properties of 3D-printed scaffolds, subsequently optimizing the architectural design (grid versus gyroid), pore size, and porosity to obtain the best compromise between mechanical properties and porosity. The selected scaffold architecture, the gyroid, exhibits morphological features reminiscent of cancellous bone; this structure was carefully tailored to promote mechanical support and facilitate cell proliferation.</div><div>This study sheds light on the significance of incorporating bioactive glass 92S6 P123 into 3D-printed scaffolds. Moreover, the tailored scaffold architecture exhibited promising results in terms of the mechanical stability and cellular invasion. This study contributes to the evolving field of scaffold design for tissue engineering applications, offering insights into the interplay between scaffold composition, architecture, and <em>in vivo</em> performance. The knowledge gained from this study holds implications for the development of advanced regenerative therapies and implantable constructs in orthopaedic and tissue engineering disciplines.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107041"},"PeriodicalIF":3.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting osteosynthesis screw failure by peri-implant bone morphology in multiple loading conditions","authors":"Juan D. Silva-Henao ,&nbsp;Dieter H. Pahr ,&nbsp;Andreas G. Reisinger","doi":"10.1016/j.jmbbm.2025.107043","DOIUrl":"10.1016/j.jmbbm.2025.107043","url":null,"abstract":"<div><div>Osteosynthesis screws are critical in orthopaedic surgery for stabilizing and aligning bone fracture fragments. Despite their importance, screw failure remains a significant complication, often due to excessive movement at the implant-bone interface resulting from both physiological loading and external mechanical forces. This study aims to enhance understanding of screw failure mechanisms by investigating the relationship between peri-implant CT-based trabecular bone morphology and screw failure under axial-, shear-, and mixed loading conditions, including the effect of plate elevation. Using high-resolution micro-computed tomography (micro-CT) and mechanical testing, 100 porcine epiphyseal bone samples were extracted and analysed to measure key CT-based trabecular morphometric indices and correlate them with mechanical failure. The study tested screws under ten different loading configurations. Statistical analyses revealed that bone volume (BV) and bone volume over total volume (BV/TV) are strong predictors of screw failure force, explaining 70–90 % of the variance in failure forces across different loading scenarios. The findings suggest that BV and BV/TV can be used to determine optimal screw implantation sites based on local bone morphology, potentially improving surgical outcomes and reducing postoperative complications. This research contributes to a more comprehensive understanding of orthopaedic screw behaviour and offers a predictive model for clinical use.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107043"},"PeriodicalIF":3.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of biodegradation on the mechanical and fatigue properties of 3D-printed PLA bone scaffolds","authors":"Hamed Bakhtiari ,&nbsp;Alireza Nouri ,&nbsp;Muhammad Aamir ,&nbsp;Mohadeseh Najafi ,&nbsp;Majid Tolouei-Rad","doi":"10.1016/j.jmbbm.2025.107039","DOIUrl":"10.1016/j.jmbbm.2025.107039","url":null,"abstract":"<div><div>A proper degradation rate of bone scaffolds ensures optimal mechanical support and effective tissue regeneration. The present study examines the degradation effects of simulated body fluids (SBF) on the compressive and fatigue strength of 3D-printed PLA bone scaffolds. Scaffolds with varying surface-to-volume (S/V) ratios and identical porosity (60 %) were immersed in Hanks' solution for a maximum period of 30 days. Static and dynamic compression tests were performed at different immersion times to assess how S/V ratio influences the degradation process. CT images showed that scaffold pore structure remained interconnected after biodegradation, with no significant change in strut thickness or dry weight. Results also indicated that while the compressive strength and modulus of scaffolds remained largely unchanged during biodegradation, their fatigue resistance reduced significantly. This reduction in fatigue resistance was attributed to the embrittlement of PLA material caused by crystalline phase changes during degradation. Microscopic images and X-ray analysis revealed the brittle fracture of scaffolds at the diagonal shear plane and the presence of SBF's salts within the scaffold material. Scaffolds with higher S/V ratios exhibited a greater decrease in fatigue resistance. The failure cycle of scaffolds with S/V ratios of 3.4, 2.4, and 1.9 mm⁻¹ decreased by 77 %, 76 %, and 60 %, respectively after 30 days of biodegradation. Higher S/V ratios increased the surface exposure to the corrosive media. This resulted in higher water absorption, which subsequently intensified the embrittlement of the scaffolds.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107039"},"PeriodicalIF":3.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable reinforcement: Mechanical and tribological performance of gel-cast fused silica composites","authors":"Rakesh Kanakam ,&nbsp;Subhash Chandra Bose Pulcharu ,&nbsp;Satish Jain ,&nbsp;Dheeraj Kumar Gara ,&nbsp;Raghavendra Gujjala ,&nbsp;Shakuntala Ojha ,&nbsp;Aswani Kumar Bandaru","doi":"10.1016/j.jmbbm.2025.107040","DOIUrl":"10.1016/j.jmbbm.2025.107040","url":null,"abstract":"<div><div>The present study investigates the mechanical performance of gel-cast fused silica composites doped with bio-waste-derived natural silica. Natural silica was extracted from rice husk, and ceramic composites were fabricated using gel casting. The tribological performance of the composites was evaluated in terms of wear rate and coefficient of friction, and mechanical performance was assessed in terms of hardness and compressive strength. Results revealed that silica doping at 10 wt% significantly enhanced wear resistance and increased the hardness from 486 HV to 569 HV and compressive strength from 0.79 GPa to 2.17 GPa. However, at 15 wt% doping, wear resistance deteriorated due to structural inconsistencies, reducing hardness to 535 HV and compressive strength to 1.43 GPa. Further insights were gained through Fourier transform Infrared spectroscopy (FTIR) analysis, which confirmed silica presence with characteristic absorption peaks at 805 cm⁻¹ and 1100 cm⁻¹. Additionally, ANOVA and regression analysis established that material composition and applied load were the most influential factors, accounting for 97.57 % of wear rate variation. This study provides a foundational benchmark for optimizing silica-doped ceramics in wear-resistant applications.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"169 ","pages":"Article 107040"},"PeriodicalIF":3.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143924516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Region-dependent properties of lamellae constituents: A microscopic insight into intervertebral disc herniation mechanisms","authors":"Jackie D. Zehr ,&nbsp;Venus Joumaa ,&nbsp;Jack P. Callaghan ,&nbsp;Walter Herzog","doi":"10.1016/j.jmbbm.2025.107045","DOIUrl":"10.1016/j.jmbbm.2025.107045","url":null,"abstract":"<div><div>Joint bending is associated with intervertebral disc (IVD) herniations. To better understand herniation disorders, the mechanics of annulus layers have been studied extensively. However, the properties and potential contributions of independent constituents (i.e., collagen fibres and the intra-lamellar matrix) to these larger-scale responses remain poorly understood but this knowledge could uncover molecular insights into herniation pathways. This study characterized the tensile properties of isolated collagen fibres and the adhesion properties of the intra-lamellar matrix in the posterior and anterior IVD regions. IVDs were extracted from eight porcine cervical spines. Single annulus layers were dissected from the anterior and posterior regions. From each layer, two separate samples were harvested: i) isolated collagen fibre and ii) two adjacent collagen fibres together with the matrix that connects them, totalling 32 samples. Once mounted, isolated fibres were longitudinally stretched while double fibre specimens were displaced with respect to each other. All preloaded specimens were strained at 1 % per second of the initial specimen length until failure occurred. From the stress-strain relationships, the Young's modulus along with stress and strain at yield and ultimate failure were determined. Within-specimen differences were evaluated with paired-tests and non-parametric Wilcoxon tests. In isolated collagen fibres, the Young's modulus and ultimate stress were 45 % and 51 % greater in the posterior region compared to the anterior region (p ≤ 0.047). All properties of intra-lamellar matrix adhesion were similar between regions (p ≥ 0.345). Interestingly, these constituents experienced comparable strains at yield (30 %) and failure (40 %), but the tensile strength of isolated fibres was approximately 5 times greater than the intra-lamellar matrix adhesion. This study demonstrated unique mechanical properties of annulus layer constituents. When incorporated into future models, these data could help discern the sequence of molecular damage leading to IVD herniations.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107045"},"PeriodicalIF":3.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hierarchical cellular structures based on TPMS mimicking cancellous bone","authors":"Fatih Pehlivan ,&nbsp;İsmail Aykut Karamanlı ,&nbsp;Abdurrahim Temiz ,&nbsp;Fatih Huzeyfe Öztürk ,&nbsp;Muhammet Mevlüt Karaca","doi":"10.1016/j.jmbbm.2025.107037","DOIUrl":"10.1016/j.jmbbm.2025.107037","url":null,"abstract":"<div><div>Innovative lightweight materials have significance in various sectors, including biomedical applications, automotive, and aerospace industries. Triply periodic minimal surface (TPMS) structures enhance the performance of these materials by providing consistent energy absorption, high specific strength, and an extensive surface area. Creating hierarchical TPMS structures has emerged as a significant research focus to enhance and optimize these features. This work investigates the mechanical performance and surface-to-volume (S/V) ratio of TPMS-based hierarchical cellular structures modelled inspired by cancellous bone. Specimens with the designated TPMS structures were constructed, systematic production planning was conducted by Taguchi design of experiments (DOE) approach and the specimens were fabricated using bio-resin on a Masked Stereolithography (MSLA) type 3D printer. The mechanical characteristics of the created constructions, including initial peak, maximum peak, and absorbed energy, were investigated using compression tests. Results showed that the DP (main diamond and wall primitive) specimen has a maximum force and initial peak of 1700 N. DP and GP specimens, specifically the main gyroid and wall primitive, exhibit enhanced energy absorption and specific energy absorption capabilities. However, while the S/V ratio, a desirable characteristic particularly in biological applications, was below 0.5 mm⁻¹ in bulk volumes, it surpassed 0.5 mm⁻¹ in TPMS structures. In hierarchical structures, this value is approximately 2 mm⁻¹ for primitive wall structures and around 4 mm⁻¹ for diamond and gyroid structures. These findings highlight the potential of hierarchical TPMS designs to improve bone integration and tissue compatibility by increasing mechanical properties and surface area.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107037"},"PeriodicalIF":3.3,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiscale characterization of jawbone treated with osteoporosis therapeutic agents","authors":"Keiichiro Watanabe ,&nbsp;Cheol-Min Han ,&nbsp;Allison R. Altman-Singles ,&nbsp;Jie Liu ,&nbsp;Xiaohan Guo ,&nbsp;Ai Ni ,&nbsp;Mason Bahador ,&nbsp;Tala Ebrahimian ,&nbsp;Jayoung Kim ,&nbsp;Beth S. Lee ,&nbsp;X. Sherry Liu ,&nbsp;Do-Gyoon Kim","doi":"10.1016/j.jmbbm.2025.107036","DOIUrl":"10.1016/j.jmbbm.2025.107036","url":null,"abstract":"<div><div>The objective of the current study was to determine whether treatments of bisphosphonate (alendronate (ALN)), parathyroid hormone (PTH), and their combination have an effect on the jawbone in estrogen deficient rats. Six female rats (4-month-old) were used for each sham surgery (SHAM). Twenty-four rats (4-month-old) were ovariectomized and randomly assigned to four equal groups: saline injection (VEH), PTH following saline injection (VEH/PTH), bisphosphonate (ALN), or a combination (ALN/PTH). A hemimandible was randomly dissected from each rat for multiscale (10⁻² to 10⁻⁷ m) characterization including static and dynamic mechanical stability of teeth in the alveolar socket, tissue mineral density distribution (TMD), and nanoindentation properties of the jawbone matrix. Most jawbone characteristics in OVX and its treatment groups were not significantly different from those of the SHAM group. The surface of alveolar bone (AB) surrounding teeth showed a trend of more erosion and addition of new bone tissues in the OVX rat groups compared to the SHAM group. All TMD parameters rapidly increased up to 60 μm from the periodontal ligament surrounding teeth regardless of the treatment groups. Treatments using each therapeutic agent and its combination did not substantially change those characteristics of jawbones in OVX rats. These findings are different from those of lumbar vertebrae in the same rats that showed a significant bone alteration by OVX and treatments. Thus, the current multiscale characterization of jawbone provides comprehensive information that can help better understand jawbone-specific responses to bone-related complications, including postmenopausal osteoporosis and bisphosphonate-related osteonecrosis of the jaw.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"169 ","pages":"Article 107036"},"PeriodicalIF":3.3,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of constitutive relations and variational formulations for modeling gastrointestinal peristalsis","authors":"Swati Sharma,&nbsp;Martin Lindsay Buist","doi":"10.1016/j.jmbbm.2025.107013","DOIUrl":"10.1016/j.jmbbm.2025.107013","url":null,"abstract":"<div><div>Gastrointestinal (GI) peristalsis is a vital process for food transport and digestion. Many methods have been formulated to model this process computationally in recent years. One such approach is the finite element (FE) method, which is efficient and robust to model peristalsis in a single framework. However, to construct a FE model, a suitable constitutive relation is required to represent the intrinsic stress–strain behavior of the tissue. Furthermore, as the GI tissues experience large deformation, an efficient variational formulation is needed to model finite deformation without numerical instabilities and volume locking. Therefore, the objective of this work was to examine the nearly incompressible and purely incompressible versions of different constitutive models and determine the most suited constitutive model for GI tissue characterization. Furthermore, we investigated various variational principles to decide on an appropriate FE approach for modeling GI peristalsis. In our study, the incompressible Humphrey’s material model was efficient in recreating experimental observations, whereas the two-field formulation for an incompressible material was an adequate variational formulation for modeling large deformation. Our model was able to recreate the experimental stress–strain data accurately with <span><math><mrow><msup><mrow><mi>R</mi></mrow><mrow><mn>2</mn></mrow></msup><mo>&gt;</mo><mn>0</mn><mo>.</mo><mn>99</mn></mrow></math></span>.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107013"},"PeriodicalIF":3.3,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of orientation of myocardial fibers on the contractility of left ventricle","authors":"Peijin Li ,&nbsp;Anqiang Sun ,&nbsp;Caixia Guo ,&nbsp;Zhilong Peng ,&nbsp;Chao Wang","doi":"10.1016/j.jmbbm.2025.107025","DOIUrl":"10.1016/j.jmbbm.2025.107025","url":null,"abstract":"<div><div>Myocardial fibers of the left ventricle (LV) play a pivotal role in electrical conduction, mechanical contraction, and numerous clinical malfunctions. While the general fiber orientation of the LV has been revealed through histological analysis and magnetic resonance diffusion tensor imaging, its impact on LV deformation remains largely unknown. In this paper, we adopt an idealized hollow semi-ellipsoid LV model, allowing for adjustable fiber orientations using a widely-accepted rule-based method. Simulations are conducted using a robustly coupled excitation-contraction nonlinear finite element algorithm. Our primary focus is on exploring the orientation angle of regularly-distributed fibers and the proportion of chaotic fibers, whose orientation angles are randomly assigned, on the end-systolic volume and ejection fraction of the LV.‌ By employing this model, we successfully recreate the changes in LV volume over a cardiac cycle and capture the typical twisting motion observed in clinical practice. Furthermore, our findings reveal that when myocardial fibers are regularly distributed and the orientation angle increases, the ejection fraction of the LV decreases along with an increase in end-systolic volume, indicating a decline in LV contractility. Additionally, both the proportion and spatial distribution of chaotic fibers within the LV influence its contractility. Specifically, an LV with a higher proportion of chaotic fibers in the basal area exhibits weaker contractility. These results provide deeper insights into the quantitative influence of myocardial fibers on LV contractility and failure, offering valuable information for further research and clinical applications.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"168 ","pages":"Article 107025"},"PeriodicalIF":3.3,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}