Journal of the Mechanical Behavior of Biomedical Materials最新文献

{"title":"Green synthesis of copper oxide nanoparticles from Murraya koenigii and its corrosion resistivity on Ti-6Al-4V dental alloy","authors":"Delinta Devadoss ,&nbsp;Ajila Asirvatham ,&nbsp;Ashok Kujur ,&nbsp;Geo Saaron ,&nbsp;Nirmala Devi ,&nbsp;John Mary S.","doi":"10.1016/j.jmbbm.2023.106080","DOIUrl":"10.1016/j.jmbbm.2023.106080","url":null,"abstract":"<div><p><span>The present work describes green-mediated copper oxide nanoparticles<span><span> as a potential corrosion inhibitor for the </span>dental alloy<span> Ti-6Al-4V. The salt of copper was reduced to metal nanoparticles using </span></span></span><em>Murraya koenigii</em><span><span> leaves, which helps with the agglomeration and nanocluster<span> formation through a reduction mechanism. The current synthesis is a single-step process and is cost-effective. The synthesized nanoparticle was characterized using UV, FTIR, XRD, </span></span>Zeta potential<span> and Particle size analyzer, SEM, and EDX<span>. The particles were then electrodeposited on Ti-6Al-4V alloy, and the corrosion resistivity in the dental medium was analyzed using Electrochemical parameters such as Corrosion current, Corrosion potential<span>, and anodic and cathodic intercepts through the Tafel and Nyquist plots. The synthesized nanoparticles showed characteristic absorbance at 359 nm. FTIR peaks confirm the phytochemical constituents present in the </span></span></span></span><em>Murraya koenigii</em><span><span> that accounts for the formation of nanoparticles. The XRD predicts the crystalline nature, which is further studied using SEM and EDX. The Zeta potential and Particle size analyzer confirms the negative-negative interactive nature of the synthesized CuO NPs. The NPs showed explicit corrosion inhibition properties with an overall inhibition efficiency of 58.15% and 25.6%, respectively. The study confirms the advantage of using Copper Oxide nanoparticles as a potential coating agent in </span>dental implant alloys in increasing its corrosion efficiency.</span></p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"146 ","pages":"Article 106080"},"PeriodicalIF":3.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro-CT analysis and mechanical properties of low dimensional CFR-PEEK specimens additively manufactured by material extrusion","authors":"Yiqiao Wang ,&nbsp;Alexander Ulbricht ,&nbsp;Franziska Schmidt ,&nbsp;Bernd R. Müller ,&nbsp;Andreas Kupsch ,&nbsp;Andreas Dominik Schwitalla","doi":"10.1016/j.jmbbm.2023.106085","DOIUrl":"10.1016/j.jmbbm.2023.106085","url":null,"abstract":"<div><p><span>Material extrusion<span> of thermoplastic polymers enables the realization of complex specific designs with high performance composites. The present study aims at evaluating the </span></span>mechanical properties<span><span> of carbon fiber-reinforced semi-crystalline thermoplastic polymer polyether ether ketone (CFR-PEEK) manufactured by material extrusion and correlating them with results obtained by micro-CT. Samples in the shape of small bars were provided by Kumovis (Munich, Germany). The determination of </span>surface roughness<span><span> and density was followed by three-point bending tests. To reveal the pore distribution as well as the fusion quality of CFR PEEK when applied with external forces, micro-CT scans were performed with an X-ray microscope before and after the mechanical test to localize the sites where the fracture is generated. The density of CFR-PEEK bars indicated that they had superior mechanical properties compared with our previous study on unfilled 3D printed PEEK (bending modulus: (5.4 ± 0.5) GPa vs. (1.05 ± 0.05) GPa to (1.48 ± 0.10) GPa; bending strength: (167 ± 11) MPa vs. (51 ± 15) to (193 ± 7) MPa). Micro-CT analyses revealed the local 3D-distribution of voids. Voids of 30 μm diameter are nearly spherical and make up the main part of the total porosity. The larger the voids, the more they deviate from a spherical shape. Significant lack-of-fusion voids are located between the deposited filaments. By growing and merging, they act as seeds for the forming fracture line in the region of the flexural specimens where the maximum local </span>tensile stresses occurred under bending load. Our work provides a detailed analysis of printed PEEK with fiber additive and relates this with mechanical properties.</span></span></p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"146 ","pages":"Article 106085"},"PeriodicalIF":3.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10651403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecularly engineered dual-network photothermal hydrogel delivery system with enhanced mechanical properties, antibacterial ability and angiogenic effect for accelerating wound healing","authors":"Guo Chen,&nbsp;Qiaoqiao Wang,&nbsp;Yumeng Zhu,&nbsp;Minqian Zhao,&nbsp;Siyuan Ma,&nbsp;Yifeng Bai,&nbsp;Jingfeng Wang,&nbsp;Meijuan Zou,&nbsp;Gang Cheng","doi":"10.1016/j.jmbbm.2023.106081","DOIUrl":"10.1016/j.jmbbm.2023.106081","url":null,"abstract":"<div><p><span><span>Bacterial infection caused by trauma and chronic wounds in the most mobile area remains a challenge in clinic. It is difficult to achieve the synergistic effects of antibacterial capacity and skin regeneration using conventional therapeutic methods. Developing a multi-functional hydrogel dressing that can cope with the complex wound environment will contribute to the healing and therapeutic effects. In this work, a novel Cur@PAM/TA-Cu photothermal hydrogel delivery system was prepared by engineering tannic acid (TA) into covalent cross-linked polyacrylamide (PAM) on which the chelating tannic acid-copper metal–polyphenolic network (TA-Cu MPN) was imposed to form dual-crosslinked networks, and the natural medicine curcumin was loaded eventually. The molecularly engineered dual-crosslinked networks resulted in enhanced </span>mechanical properties<span> including bio-adhesion, tensile strength and self-healing, which made the hydrogel suitable for dynamic wound and various application scenarios. In addition, the excellent photothermal capacity, antioxidant effect and biocompatibility of the hydrogel were demonstrated. Notably, this curcumin loaded photothermal hydrogel exhibited superior antibacterial capacity (almost 100% killing ratio to </span></span><em>E</em>. coli and <em>S</em><span>. aureus) under 808 nm laser irradiation. Meanwhile, the </span><em>in vivo</em> wound healing experiment results revealed that the anti-inflammation and proangiogenic effect of Cur@PAM/TA-Cu hydrogel successfully shortened the healing time of wound and the reconstruction of skin structure and function. Thus, this dual-crosslinked multi-functional hydrogel delivery system is a promising wound dressing for accelerating wound healing.</p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"146 ","pages":"Article 106081"},"PeriodicalIF":3.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10306810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of mechanical properties of yttria stabilized zirconia monolithic and bilayer configuration for dental application","authors":"Raíssa Monteiro Pereira ,&nbsp;Tiago Moreira Bastos Campos ,&nbsp;Estevam Augusto Bonfante ,&nbsp;Gilmar Patrocínio Thim","doi":"10.1016/j.jmbbm.2023.106160","DOIUrl":"10.1016/j.jmbbm.2023.106160","url":null,"abstract":"<div><p><span><span><span><span>Zirconia multilayer presents promising prospects, but there is scarce information about its microstructural and mechanical characterization. Therefore, this study sought to produce them in-house and to perform their characterization by comprising four groups of specimens to assess the biaxial flexural strength, </span>microhardness, </span>fracture toughness, phase characterization and quantification, </span>fractography<span><span>, and microstructural features. Weibull analysis was performed to determine the </span>Weibull modulus and characteristic strength. The results showed that bilayers 3YSZ and 5YSZ presented intermediate </span></span>mechanical properties when compared to 3YSZ and 5YSZ monolithic controls (680 MPa, 464 MPa, 885 MPa, 594 MPa, respectively). Fractographic analysis revealed that the failure origin was not at the interface in the bilayer groups, but residual stress was present between the layers. Hardness and fracture toughness were not affected by the interface.</p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"148 ","pages":"Article 106160"},"PeriodicalIF":3.9,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling the biomechanics of laser corneal refractive surgery","authors":"Andrea Montanino ,&nbsp;Sanne van Overbeeke ,&nbsp;Anna Pandolfi","doi":"10.1016/j.jmbbm.2023.105998","DOIUrl":"https://doi.org/10.1016/j.jmbbm.2023.105998","url":null,"abstract":"<div><p>We present a finite element<span> model of the human cornea used to simulate corneal refractive surgery according to the three most diffused laser procedures, i. e., photo-refractive keratectomy (PRK), laser in-situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE). The geometry used for the model is patient-specific in terms of anterior and posterior surfaces of the cornea and intrastromal surfaces originated by the planned intervention. The customization<span> of the solid model prior to finite element discretization avoids the struggling difficulties associated with the geometrical modification induced by cutting, incision and thinning. Important features of the model include the identification of the stress-free geometry and an adaptive compliant limbus to account for the surrounding tissues. By the way of simplification, we adopt a Hooke material model extended to the finite kinematics, and consider only the preoperative and short-term postoperative conditions, disregarding the remodeling and material evolution aspects typical of biological tissues. Albeit simple and incomplete, the approach demonstrates that the post-operative biomechanical state of the cornea, after the creation of a flap or the removal of a small lenticule, is strongly modified with respect to the preoperative state and characterized by displacement irregularities and stress localizations.</span></span></p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"145 ","pages":"Article 105998"},"PeriodicalIF":3.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2969770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Jacketed elastomeric tubes for passive self-regulation of pulsatile flow","authors":"Nathan Jen ,&nbsp;Jake Hadfield ,&nbsp;Guilherme M. Bessa ,&nbsp;Marco Amabili ,&nbsp;David S. Nobes ,&nbsp;Hyun-Joong Chung","doi":"10.1016/j.jmbbm.2023.105994","DOIUrl":"https://doi.org/10.1016/j.jmbbm.2023.105994","url":null,"abstract":"<div><p><span><span>Regulating pulsatile flow is important to achieve optimal separation and mixing and enhanced heat transfer in microfluidic devices, as well as maintaining homeostasis in biological systems. The human aorta, a composite and layered tube made (among others) of </span>elastin<span> and collagen, is an inspiration for researchers who seek an engineering solution for a self-regulation of pulsatile flow. Here, we present a bio-inspired approach showing that fabric-jacketed elastomeric tubes, manufactured using commercially available silicone rubber and knitted textiles, can be used to regulate pulsatile flow. Our tubes are evaluated via incorporation into a mock-circulatory ‘flow loop’ that replicates the pulsatile fluid flow conditions of an ex-vivo heart perfusion (EVHP) device, a machine used in heart transplants. Pressure </span></span>waveforms measured<span> near the elastomeric tubing clearly indicated an effective flow regulation. The ‘dynamic stiffening’ behavior of the tubes during deformation is analyzed quantitatively. Broadly, the fabric jackets allow for the tubes to experience greater magnitudes of pressure and distension without risk of asymmetric aneurysm within the expected operating time of an EVHP. Owing to its highly tunable nature, our design may serve as a basis for tubing systems that require passive self-regulation of pulsatile flow.</span></p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"145 ","pages":"Article 105994"},"PeriodicalIF":3.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1629483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated model discovery for muscle using constitutive recurrent neural networks","authors":"Lucy M. Wang,&nbsp;Kevin Linka,&nbsp;Ellen Kuhl","doi":"10.1016/j.jmbbm.2023.106021","DOIUrl":"https://doi.org/10.1016/j.jmbbm.2023.106021","url":null,"abstract":"<div><p>The stiffness of soft biological tissues not only depends on the applied deformation, but also on the deformation rate. To model this type of behavior, traditional approaches select a specific time-dependent constitutive model and fit its parameters to experimental data. Instead, a new trend now suggests a machine-learning based approach that simultaneously discovers both the best model and best parameters to explain given data. Recent studies have shown that feed-forward constitutive neural networks can robustly discover constitutive models and parameters for hyperelastic materials. However, feed-forward architectures fail to capture the history dependence of viscoelastic soft tissues. Here we combine a feed-forward constitutive neural network for the hyperelastic response and a recurrent neural network for the viscous response inspired by the theory of quasi-linear viscoelasticity. Our novel rheologically-informed network architecture discovers the time-independent initial stress using the feed-forward network and the time-dependent relaxation using the recurrent network. We train and test our combined network using unconfined compression relaxation experiments of passive skeletal muscle and compare our discovered model to a neo Hookean standard linear solid, to an advanced mechanics-based model, and to a vanilla recurrent neural network with no mechanics knowledge. We demonstrate that, for limited experimental data, our new constitutive recurrent neural network discovers models and parameters that satisfy basic physical principles and generalize well to unseen data. We discover a Mooney–Rivlin type two-term initial stored energy function that is linear in the first invariant <span><math><msub><mrow><mi>I</mi></mrow><mrow><mn>1</mn></mrow></msub></math></span> and quadratic in the second invariant <span><math><msub><mrow><mi>I</mi></mrow><mrow><mn>2</mn></mrow></msub></math></span> with stiffness parameters of 0.60 kPa and 0.55 kPa. We also discover a Prony-series type relaxation function with time constants of 0.362s, 2.54s, and 52.0s with coefficients of 0.89, 0.05, and 0.03. Our newly discovered model outperforms both the neo Hookean standard linear solid and the vanilla recurrent neural network in terms of prediction accuracy on unseen data. Our results suggest that constitutive recurrent neural networks can autonomously discover both model and parameters that best explain experimental data of soft viscoelastic tissues. Our source code, data, and examples are available at <span>https://github.com/LivingMatterLab</span><svg><path></path></svg>.</p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"145 ","pages":"Article 106021"},"PeriodicalIF":3.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3209012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the use of antioxidant agents after dental bleaching compromise the aesthetic results of ceramic laminate veneers?","authors":"Henrico Badaoui Strazzi-Sahyon ,&nbsp;André Luiz Fraga Briso ,&nbsp;Paulo Henrique dos Santos","doi":"10.1016/j.jmbbm.2023.106027","DOIUrl":"10.1016/j.jmbbm.2023.106027","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;p&gt;This &lt;em&gt;in vitro&lt;/em&gt;&lt;span&gt; study aimed to evaluate the aesthetic compromise generated in adhesive interface of ceramic laminate veneer luted after tooth bleaching and the use of antioxidant agents. Thus, the chromatic coordinates and whitening index (&lt;/span&gt;&lt;em&gt;WI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt;) were evaluated, comparing whiteness changes &lt;em&gt;(ΔWI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt;&lt;em&gt;)&lt;/em&gt; results to perceptibility and acceptability thresholds.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Material and methods&lt;/h3&gt;&lt;p&gt;&lt;span&gt;In total, 88 bovine enamel samples (7 × 8 × 4 mm; n = 8) were submitted to the ceramic laminate veneer luting protocol according to surface treatment (unbleached and bleached enamel), antioxidant agents (control; 10% ascorbic acid and 10% α-tocopherol), and luting periods (after 24 h and after 14 days). To lute IPS e.max ceramic restorations (7 × 8 × 0.6 mm), Tetric N-Bond Universal adhesive system and Variolink Aesthetic LC resin cement were used. An ultraviolet–visible spectrophotometer (UV–VIS) was utilized to measure CIE L*a*b* coordinates prior to and after UV-B artificial accelerated aging for 252, 504, and 756 h. L*, a*, and b* axes were evaluated separately, and the whitening stability (Δ&lt;/span&gt;&lt;em&gt;WI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt;) effect was assessed by varying the whiteness index for dentistry (&lt;em&gt;WI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt;). The 50:50% visual threshold was used to evaluate &lt;em&gt;ΔWI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt; values (whiteness perceptibility [WPT] and whiteness acceptability [WAT]). Color parameters changes (&lt;em&gt;Δ&lt;/em&gt;L*&lt;em&gt;Δ&lt;/em&gt;a*&lt;em&gt;Δ&lt;/em&gt;b*), &lt;em&gt;WI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;,&lt;/sub&gt; and &lt;em&gt;ΔWI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt; data were subjected to 2-way repeated measures ANOVA followed by Tukey's test (α = 0.05).&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;Different UV-aging periods influenced the chromatic coordinates, &lt;em&gt;WI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D,&lt;/em&gt;&lt;/sub&gt; and &lt;em&gt;ΔWI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt; of the ceramic restorations regardless of the bleaching treatment, antioxidant solutions and luting periods (P &lt; .05). In general, &lt;em&gt;ΔWI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt; values after UV-aging periods were above perceptibility and acceptability thresholds (WPT = 0.72 and WAT = 2.62, respectively) for all experimental groups (P &lt; .05). Unbleached and 10% ascorbic acid-treated enamels luted after 14 days of the antioxidant action exhibited lower &lt;em&gt;Δ&lt;/em&gt;L* and &lt;em&gt;Δ&lt;/em&gt;b* values, while control group showed lower &lt;em&gt;Δ&lt;/em&gt;a* values. All experimental groups showed similar performance on &lt;em&gt;ΔWI&lt;/em&gt;&lt;sub&gt;&lt;em&gt;D&lt;/em&gt;&lt;/sub&gt; compared to the control group, regardless of the UV-aging period analyzed (P &gt; .05).&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;p&gt;α-tocopherol is a suitable antioxidant solution to be used 24 h post enamel bleaching not compromising clinical acceptability of ceramic laminate veneers.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Clinical relevance&lt;/h3&gt;&lt;p&gt;The adhesive interface of ceramic laminate veneers may appear darker after the use of antioxidant agents affecting the clinical acce","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"145 ","pages":"Article 106027"},"PeriodicalIF":3.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10318651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Impact of test environment on the fracture resistance of cortical bone” [J. Mech. Behav. Biomed. Mater. 129 (2022) 105155]","authors":"Mihee Shin ,&nbsp;Min Zhang ,&nbsp;Annika vom Scheidt ,&nbsp;Matthew H. Pelletier ,&nbsp;William R. Walsh ,&nbsp;Penny J. Martens ,&nbsp;Jamie J. Kruzic ,&nbsp;Björn Busse ,&nbsp;Bernd Gludovatz","doi":"10.1016/j.jmbbm.2023.106024","DOIUrl":"10.1016/j.jmbbm.2023.106024","url":null,"abstract":"","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"145 ","pages":"Article 106024"},"PeriodicalIF":3.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1751616123003776/pdfft?md5=29f6ffa8f6eb36e69aca9a0a84e6ec06&pid=1-s2.0-S1751616123003776-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9935737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collagen fibril tensile response described by a nonlinear Maxwell model","authors":"Martin Handelshauser ,&nbsp;You-Rong Chiang ,&nbsp;Martina Marchetti-Deschmann ,&nbsp;Philipp J. Thurner ,&nbsp;Orestis G. Andriotis","doi":"10.1016/j.jmbbm.2023.105991","DOIUrl":"https://doi.org/10.1016/j.jmbbm.2023.105991","url":null,"abstract":"<div><p>Collagen fibrils are the basic structural building blocks that provide mechanical properties such as stiffness, toughness, and strength to tissues from the nano- to the macroscale. Collagen fibrils are highly hydrated and transient deformation mechanisms contribute to their mechanical behavior. One approach to describe and quantify the apparent viscoelastic behavior of collagen fibrils is to find rheological models and fit the resulting empirical equations to experimental data. In this study, we consider a nonlinear rheological Maxwell model for this purpose. The model was fitted to tensile stress-time data from experiments conducted in a previous study on hydrated and partially dehydrated individual collagen fibrils via AFM. The derivative tensile modulus, estimated from the empirical equation, increased for decreasing hydration of the collagen fibril. The viscosity is only marginally affected by hydration but shows a dependency with strain rate, suggesting thixotropic behavior for low strain rates.</p></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"145 ","pages":"Article 105991"},"PeriodicalIF":3.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3340916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}