Revista de Senologia y Patologia Mamaria最新文献

{"title":"Linfedema secundario a cáncer de mama: una revisión narrativa del papel del ejercicio físico","authors":"Ana Belén Puentes Gutiérrez ,&nbsp;Elena Vaquero Ramiro ,&nbsp;María García Bascones","doi":"10.1016/j.senol.2025.100681","DOIUrl":"10.1016/j.senol.2025.100681","url":null,"abstract":"<div><div>The role of exercise in breast cancer-related lymphedema (BCRL) is not clearly defined. The main target of this review is to describe the effects of the different types of exercises on this kind of patient. Bibliographic research was done through the databases of PubMed and PEDro. Controlled trials published between 2017 and 2023 in both Spanish and English, were included. Article selection was carried out separately by 2 researchers using the PICO strategy. Forty-three articles were selected and, after the authors´ review, 19 were included, the majority focused on strength exercises. Strength physical exercise in women with BCRL or at risk of developing it, proved to be safe, even with heavy loads and even during taxanes treatment. Furthermore, it has a beneficial effect on the patients quality of life, in lymphedema symptoms, extremities functionality, and strength gain, although it could not prove its positive role in the prevention or treatment of BCRL. There are no specific protocols for the strength exercise. Other types of exercises such as water sports, pilates, and yoga are considered adequate for these patients.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100681"},"PeriodicalIF":0.3,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cirugía oncoplástica reconstructiva: reconstrucción prepectoral inmediata y matrices acelulares dérmicas. Revisión sistemática, indicaciones y resultados","authors":"Manuel Nogueira Sixto,&nbsp;Gonzalo de Castro Parga,&nbsp;Vanesa Rodríguez Fernández","doi":"10.1016/j.senol.2025.100702","DOIUrl":"10.1016/j.senol.2025.100702","url":null,"abstract":"<div><div>In the last decade, we have witnessed an exponential increase in the use of acellular dermal matrices (ADMs) as a result of increased rates of immediate prepectoral breast reconstruction (IPBR) after mastectomy. We performed a systematic search on IPBR with ADMs with the aim of understanding the results obtained and identifying which subgroup of patients benefit from the use of ADMs in IPBR. We recorded the anthropometric characteristics and medical history of the patients, the therapy carried out, and the results obtained.</div><div>A total of 159 articles were identified, of which 46 were selected. These describe a reduction in the onset of global complications after IPBR with ADMs from 27.5% to 23.3%, and a reduction in the incidence of capsular contracture from 12.4% to 2.3%, as well as the disappearance of animation deformity. In this review, the following factors were found to be risk factors for morbidity and/or worse aesthetic results: adjuvant radiotherapy, smoking, larger volume mastectomy, and axillary surgery. BMI &gt; 30, diabetes, age &gt;<!--> <!-->50, and prosthetic volume have not been confirmed as risk factors. Mastectomies &gt;<!--> <!-->1000 g have been described as protective factors. Prepectoral breast reconstruction with ADMs is a safe technique with good functional and aesthetic results. At present, it is not possible to determine which ADM provides the best results.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100702"},"PeriodicalIF":0.3,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cystic neutrophilic granulomatous mastitis associated with Corynebacterium: A systematic review of clinical, pathological, and therapeutic insights","authors":"André R. Guimarães ,&nbsp;Ana Pereira Marques ,&nbsp;António Sarmento","doi":"10.1016/j.senol.2025.100704","DOIUrl":"10.1016/j.senol.2025.100704","url":null,"abstract":"<div><div>Cystic neutrophilic granulomatous mastitis (CNGM) is a rare and underrecognized subtype of granulomatous mastitis, increasingly associated with <em>Corynebacterium</em> species, particularly <em>Corynebacterium kroppenstedtii</em>. Despite a growing number of reports, its diagnosis remains challenging, and treatment approaches are highly variable.</div><div>This systematic review aimed to consolidate the clinical, microbiological, and therapeutic characteristics of CNGM to better inform clinical management. A structured search of PubMed using MeSH terms identified 13 studies, of which 11 met inclusion criteria.</div><div>These studies, encompassing 387 patients, were analyzed for clinical presentation, diagnostic methods, histopathological findings, bacterial species, antimicrobial susceptibility, treatment strategies, and outcomes. CNGM typically presented as a unilateral painful breast mass, frequently accompanied by abscess, nipple inversion, or fistulae. Diagnosis was established via histopathology and confirmed by microbiological testing, often through MALDI-TOFMS or 16S rRNA sequencing. While <em>C. kroppenstedtii</em> was most frequently isolated, recent studies suggest <em>C. parakroppenstedtii</em> may be more prevalent than previously recognized. Antimicrobial susceptibility data revealed consistent resistance to beta-lactams and variable susceptibility to clindamycin and fluoroquinolones, whereas linezolid and vancomycin demonstrated consistent efficacy. Directed antibiotic therapy, particularly with lipophilic agents, combined with abscess drainage, was associated with improved outcomes and lower recurrence. In contrast, higher recurrence rates were reported with corticosteroids or immunosuppressants used in isolation.</div><div>These findings support a multimodal approach as the most effective strategy for CNGM management. Further prospective studies are needed to establish standardized diagnostic criteria and evidence-based treatment guidelines.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 3","pages":"Article 100704"},"PeriodicalIF":0.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silent complications: Liquid silicone granuloma in a patient after unregulated cosmetic mamary augmentation","authors":"Guillermo Lillo-Albert ,&nbsp;Ernesto Muñoz-Sornosa ,&nbsp;Marcos Adrianzén-Vargas ,&nbsp;Vicente López-Flor ,&nbsp;Elvira Buch-Villa","doi":"10.1016/j.senol.2025.100701","DOIUrl":"10.1016/j.senol.2025.100701","url":null,"abstract":"","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 3","pages":"Article 100701"},"PeriodicalIF":0.3,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radioterapia adyuvante en el cáncer de mama: análisis comparativo de la toxicidad de 2 esquemas de hipofraccionamiento","authors":"Laura Vaya González,&nbsp;Clara Iglesias Melero,&nbsp;María Soledad Quesada Muñoz,&nbsp;María Domínguez Rodríguez,&nbsp;José Manuel Rico Pérez,&nbsp;Nuria Azahara Linares Mesa","doi":"10.1016/j.senol.2025.100697","DOIUrl":"10.1016/j.senol.2025.100697","url":null,"abstract":"<div><h3>Objective</h3><div>Adjuvant radiotherapy (RT) for breast cancer has been given in 1.8–2 Gy daily fractions for decades. Protracted schemes have proven as effective and safe as conventional. Schemes involving 5 fractions once a week are as safe as those involving one daily fraction for three weeks. We compared acute and late toxicity of two hypofractionated regimes.</div></div><div><h3>Material and methods</h3><div>Retrospective single-center observational study involving 100 unselected patients, treated with adjuvant radiotherapy for breast cancer with either 40 Gy/15 fr/3 weeks or 28,5 Gy/5 fr/5 weeks (1:1 ratio). Statistical tests used: Mann–Whitney U and Chi-square (χ²). Toxicity (assessed by physicians/nurses using RTOG/CTCAE Score at end of treatment, one month and six months later) was retrieved from patients notes.</div></div><div><h3>Results</h3><div>Median follow-up: 16.6 months. Average age: 59 years. The comparison between the 15-session and 5-session groups revealed the following results: boost: 24% vs. 2%; lumpectomy: 62% vs. 92%; mastectomy 38% vs. 14%; lymphadenectomy 36% vs. 14%; RT to SCF + level III: 54% vs. 8%; acute skin toxicity 70% vs. 60%; acute odynophagia: 16% vs. 2%; late toxicity (induration, edema, deformity-distortion, telangiectasias, hyperpigmentation) 30% vs. 52%.</div></div><div><h3>Conclusion</h3><div>Odynophagia was more frequent in weekly treatments. Prophylactic nodal irradiation rates could be a confounding factor. A modest excess of G1 breast induration in 5 fractions schemes was detected. To summarize, both schemes are similar concerning acute and late toxicity.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100697"},"PeriodicalIF":0.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143923626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subutilización de los colgajos perforantes en cirugía oncoplástica: análisis clínico y barreras terminológicas","authors":"Pablo Sciuto ,&nbsp;Maite Campos ,&nbsp;Daniel Gonzalez","doi":"10.1016/j.senol.2025.100698","DOIUrl":"10.1016/j.senol.2025.100698","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the safety, efficacy, and esthetic outcomes of chest wall perforator flaps in breast-conserving surgery and to analyze the terminological barriers affecting their adoption.</div></div><div><h3>Materials and methods</h3><div>A retrospective observational study was conducted on 27 patients treated between 2020 and 2024 with breast-conserving surgery and partial breast reconstruction using perforator flaps of the lateral intercostal artery (LICAP, Lateral Intercostal Artery Perforator), lateral thoracic artery (LTAP, Lateral Thoracic Artery Perforator), and medial intercostal artery (MICAP, Medial Intercostal Artery Perforator). Clinical variables, flap selection, complications, and esthetic outcomes were analyzed using the Harvard Scale. Follow-up included immediate postoperative assessment and evaluation at one year.</div></div><div><h3>Results</h3><div>A total of 85.2% of patients achieved good or excellent esthetic outcomes, with no changes in Harvard Scale scores at one year. No patient requested symmetry surgery. Eight complications were reported (29.6%), mostly minor (seromas, hematomas, partial fat necrosis), all managed conservatively. One case of flap necrosis required mastectomy. No surgical site infections or wound dehiscence were documented. The complication rate and esthetic success were comparable to international series.</div></div><div><h3>Conclusion</h3><div>Chest wall perforator flaps represent a safe and effective option in breast-conserving surgery, with low morbidity and excellent esthetic acceptance. The lack of consensus in nomenclature remains a barrier to widespread adoption. Standardization and structured training programs are essential to optimize their clinical application.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100698"},"PeriodicalIF":0.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143918216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tissue reaction of the hydrogel marker HydroMARK©","authors":"Francesc Tresserra,&nbsp;Jorge Perez-Fuentes,&nbsp;Carmen Ara","doi":"10.1016/j.senol.2025.100699","DOIUrl":"10.1016/j.senol.2025.100699","url":null,"abstract":"","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 3","pages":"Article 100699"},"PeriodicalIF":0.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic cortisol correlates with poor prognosis parameters in women with breast cancer and excessive body fat","authors":"Aedra Carla Bufalo Kawassaki ,&nbsp;Carolina Coradi ,&nbsp;Elaine Minatti ,&nbsp;Janaina Carla da Silva ,&nbsp;Daniel Rech ,&nbsp;Thalita Basso Scandolara ,&nbsp;Fernanda Tomiotto-Pelissier ,&nbsp;Carolina Panis ,&nbsp;Wander Rogerio Pavanelli","doi":"10.1016/j.senol.2025.100700","DOIUrl":"10.1016/j.senol.2025.100700","url":null,"abstract":"<div><h3>Introduction</h3><div>Excessive body fat can lead to systemic hormonal deregulation associated with poor cancer prognosis. This study analyzed the relationship between systemic cortisol levels and clinicopathological parameters in breast cancer patients categorized by body mass index (BMI).</div></div><div><h3>Material and methods</h3><div>Peripheral blood samples were collected from 223 women with or without breast cancer to investigate daytime cortisol levels. Circulating cortisol was measured using an enzyme immunoassay kit and correlated with clinicopathological data. The Cancer Genome Atlas (TCGA) data were collected to visualize cortisol axis-related gene expression in breast tumors (<em>n</em> = 1215).</div></div><div><h3>Results</h3><div>No significant difference in cortisol levels was found concerning breast cancer diagnosis. However, when breast cancer patients were stratified by BMI, cortisol levels were significantly higher in obese patients compared to eutrophics. Eutrophic patients exhibited lower cortisol levels when they had Luminal A tumors compared to those with HER2-amplified tumors. Obese patients with Luminal B tumors had higher cortisol levels than those carrying Luminal A, HER2, or triple-negative tumors. Additionally, lymph node metastasis correlated with high cortisol levels and obesity, as did the presence of blood clots.</div></div><div><h3>Conclusions</h3><div>These findings suggest that obesity and systemic cortisol levels in breast cancer patients should be further explored to understand their relationship with clinicopathological parameters.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100700"},"PeriodicalIF":0.3,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inteligencia artificial en el diagnóstico por imagen de patología mamaria","authors":"Marina Álvarez-Benito,&nbsp;Esperanza Elías-Cabot,&nbsp;Sara Romero-Martín","doi":"10.1016/j.senol.2025.100684","DOIUrl":"10.1016/j.senol.2025.100684","url":null,"abstract":"<div><div>Artificial Intelligence systems are showing great development in the field of medical imaging. Its role in population screening programs stands out, where these systems can solve many of the problems detected, such as the lack of sensitivity and specificity of mammography, the workload involved in reading a significant number of studies or the introduction of tomosynthesis.</div><div>The ability of AI systems to establish the risk of breast cancer in an agile way undoubtedly represents a very important step towards personalized screening that will allow the selection of technique and frequency for each patient, or the administration of preventive measures and treatments in women at high risk.</div><div>Radiomics analysis of breast cancers from different modalities and in combination with other clinical-pathological data improves tumor characterization, as well as the prediction of prognosis and response to certain therapies.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100684"},"PeriodicalIF":0.3,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fundamentals of artificial intelligence","authors":"Rafael Guzmán Robles","doi":"10.1016/j.senol.2025.100685","DOIUrl":"10.1016/j.senol.2025.100685","url":null,"abstract":"<div><div>Artificial Intelligence (AI) is revolutionizing various industries, with healthcare being one of the most impacted sectors. This article explores the fundamentals of AI, with a specific focus on machine learning, deep learning, and generative AI. Machine learning, a subset of AI, enables systems to identify patterns in large data sets, improving over time without being explicitly programmed. Deep learning, a more advanced subfield, uses multi-layered neural networks to process complex information. The advent of generative AI, such as GPT and GANs, has expanded the potential of AI to create new content autonomously, transforming areas like drug discovery and personalized medicine. The article also addresses the ethical considerations surrounding the use of AI, particularly concerning data privacy, algorithmic bias, and equitable access to AI-driven technologies. These considerations are essential for ensuring the responsible development and implementation of AI in healthcare.</div></div>","PeriodicalId":38058,"journal":{"name":"Revista de Senologia y Patologia Mamaria","volume":"38 4","pages":"Article 100685"},"PeriodicalIF":0.3,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}